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German pharmaceutical firm Merck has extended its partnership with Moderna to jointly develop and sell mRNA-4157/V940, an investigational personalised cancer vaccine (PCV). They subsequently expanded the collaboration to include the development of antigen mRNA cancer vaccines in 2018.
Moderna and MSD have announced follow-up data from the Phase IIb clinical trial evaluating cancer vaccine mRNA-4157 (V940) in combination with MSD’s Keytruda in patients with resected high-risk melanoma. The post Positive results for mRNA vaccine in melanoma patients appeared first on European Pharmaceutical Review.
These programmes will include therapies and vaccines in infectious disease and oncology areas. Preclinical data showed the potential of oRNA expression and delivery as a method for advanced development in various areas, including vaccines and oncology treatments. Topic sponsors are not involved in the creation of editorial content.
Merck ResearchLaboratories president Dr Dean Li said: “Targeting CYP11A1 provides a compelling approach to suppressing the production of steroid hormones, a key driver of prostate cancer. “We The latest deal complements and bolsters the oncology pipeline of Merck.
These prestigious awards, organized by IMAPAC, recognize organizations and technologies that contribute to vaccineresearch and development (R&D) and biologics manufacturing excellence in developing economies, particularly India. The focus is on enhanced speed, reduced cost, and superior quality.
Merck (MSD outside of the US and Canada) has entered into a collaboration agreement with Orna Therapeutics to discover, develop and commercialise multiple programmes of engineered circular RNA (oRNA) therapies, including vaccines and therapeutics in the areas of infectious disease and oncology.
The US Food and Drug Administration (FDA) has granted approval for Merck's (MSD outside the US and Canada) pneumococcal 15-valent conjugate vaccine, Vaxneuvance, for use in children aged six weeks to 17 years. The post US FDA grants approval for Merck’s pneumococcal vaccine for children appeared first on Pharmaceutical Technology.
The safety and efficacy of mRNA vaccines should be a game changer and is the likely solution to antibiotic-resistant microorganisms and emerging viral pathogens.” The previous record for vaccine development and approval was four years for the measles vaccine. Perhaps we will see a universal flu vaccine in the near future.
MSD has announced it has opened a new $1 billion vaccine manufacturing facility at its site in Durham, North Carolina, US. MSD shared that a further $8 billion of US capital investment is anticipated by 2028.
Expanding treatment options for atherosclerosis with an Lp(a) inhibitor “The drug is an important addition that expands and complements our cardio-metabolic pipeline, remarked Dr Dean Li, President, Merck ResearchLaboratories.
The formal signing ceremony of the MoU today at Cerba Research’s Ghent office was led by Mario Papillon, CEO of Cerba Research, and Xu Yi, CEO of Teddy Lab, on behalf of their respective organisations. I am proud and humble to say that, together, Cerba Research and Teddy Lab have contributed greatly to the fight against the pandemic.
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