Presentation - Pharmacist Digest

Experts say leaked messages present false link between gender-affirming care and cancer

STAT

MARCH 11, 2024

Hundreds of messages from an internal chat board for an international group of transgender health professionals were leaked in a think tank report last week and framed as revealing serious health risks associated with gender-affirming care, including cancer.

Opinion: Diagnostic tests for rare conditions present a mathematical conundrum

STAT

NOVEMBER 30, 2023

Worried about your health? You can now avail yourself of noninvasive diagnostics that claim to screen for rare birth defects, cancer-associated mutations, and even Alzheimer’s.

Labelling

STAT+: Genentech, a biotech with a storied past, confronts new turbulence in the present

STAT

SEPTEMBER 16, 2024

For decades, the biotech company Genentech has carved out a reputation in the industry as a scientist’s paradise, a place where researchers have developed new therapies in-house and published high-impact papers.

STAT+: Recursion presents mixed data on lead AI-derived drug candidate for potentially fatal brain condition

STAT

SEPTEMBER 3, 2024

Recursion Pharmaceuticals announced results of a clinical trial for its lead drug candidate Tuesday that, while a success on paper, likely won’t satisfy many investors closely watching the AI drug developer.

Drug Development

Opinion: Racism infects neuroscience’s past and present. What about its future?

STAT

DECEMBER 20, 2023

De-Shaine Murray is working at the cutting edge of neurotechnology. As a postdoctoral fellow at Yale, he is developing a device to monitor the brain following traumatic brain injury or stroke. He is also trying to fight the long legacy of racism in neuroscience.

STAT+: Truvian presents data for its desktop blood-testing device in a field still in Theranos’s shadow

STAT

JULY 25, 2023

The findings were presented at the annual meeting of the American Association for Clinical Chemistry, recently rebranded as the Association for Diagnostics & Laboratory Medicine. It’s the first time Truvian has shared clinical data on its product, though they have not been published in a peer-reviewed journal.

STAT+: From Epic to FDA, all the leaders presenting at HHS’ invite-only AI in health care event

STAT

SEPTEMBER 17, 2024

Federal health officials wrestling with when and how to use artificial intelligence will on Wednesday host an invitation-only meeting of AI leaders across industry, academia, and government. Called “AI in Action: Transforming Health and Human Services,” the three-hour event is hosted by the federal health department.

Medical Schools

Medical Schools Hospitals

Opioid cravings were reduced by anti-obesity drug in small study

STAT

FEBRUARY 17, 2024

DENVER — The GLP-1 medication liraglutide significantly reduced opioid cravings in a small analysis presented on Saturday. It is the first randomized controlled trial to test anti-obesity drugs against opioid addiction, which kills around 80,000 people in the U.S. Read the rest…

STAT+: At ASCO, AstraZeneca says its CAR-T therapy shrank solid liver tumors in early trial

STAT

JUNE 3, 2024

CHICAGO — A next-generation CAR-T therapy was able to substantially shrink tumors in patients with liver cancer in early clinical data presented Monday at the American Society of Clinical Oncology annual meeting.

STAT+: Nvidia says a biological revolution is happening now. But is it?

STAT

JANUARY 9, 2024

The occasion: Nvidia, the chipmaker whose market capitalization has soared beyond $1 trillion because of its role in the revolutionary work occurring in artificial intelligence, was presenting at the J.P. ” When Kimberly Powell, Nvidia’s vice president of health care, finished her presentation, the room erupted in applause.

STAT+: Roche drug slashes recurrence, death risk in lung cancer that afflicts younger patients

STAT

OCTOBER 21, 2023

MADRID — A Roche drug lowered the risk of recurrence or death by 76% versus chemotherapy for patients with a type of early non-small cell lung cancer, according to data from a Phase 3 trial presented Saturday. The results from the Alina trial were presented here at the annual meeting of the European Society for Medical Oncology.

Chemotherapy

Chemotherapy Drug Development

STAT+: Under-the-skin injection of Eisai’s Leqembi is as effective as IV infusion, new Alzheimer’s data show

STAT

OCTOBER 25, 2023

A version of the Alzheimer’s disease drug Leqembi that can be given with a simpler, under-the-skin injection is equally effective as the currently approved intravenous infusion, according to study results presented Wednesday by its maker, Eisai.

Palliative care for cancer patients is found to be as effective given virtually as in person

STAT

JUNE 2, 2024

CHICAGO — Comfort can be delivered to patients with advanced cancer virtually just as well as in person, according to a new study presented on Sunday at the American Society of Clinical Oncology annual meeting in Chicago.

Hospitals

STAT+: Could kidney transplant patients be spared a lifetime of immunosuppressants?

STAT

NOVEMBER 2, 2023

These treatments have side effects and toxicities that impact patients’ long-term health, and even survival, leading to a transplant failure rate of 30-50% at the 10-year mark. Continue to STAT+ to read the full story…

Scientists document first-ever transmitted Alzheimer’s cases, tied to no-longer-used medical procedure

STAT

JANUARY 29, 2024

Part of it was the patients’ presentations: Some didn’t have the classic symptoms of the condition. LONDON — There was something odd about these Alzheimer’s cases. But it was also that the patients were in their 40s and 50s, even their 30s, far younger than people who normally develop the disease.

Documentation

STAT+: ResMed CEO on how wearables, GLP-1s will impact sleep apnea device sales

STAT

OCTOBER 2, 2024

NEW YORK — The morning after presenting an upbeat outlook to analysts in a gilded hall in the New York Stock Exchange building, Mick Farrell, the CEO of ResMed, looked refreshed, despite a post-presentation cocktail reception. If the sleep tech magnate could have used more shuteye, he didn’t show it.

Global health leader critiques ‘ineptitude’ of U.S. response to bird flu outbreak among cows

STAT

JUNE 13, 2024

In a presentation in London about vaccine development, Berkley, the former CEO of Gavi, the Vaccine Alliance, raised the issue of H5N1 bird flu when discussing whether the world was ready for another pandemic following its experience with Covid-19.

Vaccines

Dietary experts advise skipping guidelines on ultra-processed foods — for now

STAT

OCTOBER 21, 2024

Meeting Monday, the first of two days of presentations, they discussed research findings to inform a report to the Department of Health and Human Services and the Department of Agriculture. The results will be published in December.

STAT+: With an old approach but new energy, ADCs take center stage as promising cancer treatments

STAT

OCTOBER 24, 2023

MADRID — If you had to pinpoint one subject that stood out at this year’s European Society for Medical Oncology meeting , a massive conference with thousands of people from 140-some countries and 2,500 studies presented, it would be a burgeoning type of cancer treatment called antibody-drug conjugates.

Compounding

Compounding Drug Development

SAEM Clinical Images Series: Purple Finger

ALiEM - Pharm Pearls

MARCH 18, 2024

A 30-year-old female with a past medical history of Crohn’s Disease presented to the ED for evaluation of an acutely bruised right 4th finger. She stated she was typing on a computer keyboard approximately 10 minutes prior to presentation and she noticed a sudden popping sensation at the base of her right ring finger.

Opinion: Pumping milk at JPM was a nightmare. It’s part of a bigger problem in the industry

STAT

JANUARY 11, 2024

Somehow, between back-to-back meetings and presentations, I’d have to bust out that abominable contraption and do my thing. But skipping a session ends up being even more painful. Naturally, I expected navigating the J.P. Morgan Healthcare Conference in San Francisco would be more complicated this year.

Male birth control research wins audience over at STAT Madness event

STAT

MARCH 22, 2024

That’s what attendees at the Breakthrough Summit East in New York had on their hands Thursday, as four participants presented their work in this year’s STAT Madness competition — an annual March Madness bracket-style battle to find the best innovation in science and medicine. A little madness. Read the rest…

STAT+: Summit Therapeutics vs. Merck: Prepping for a big lung cancer study reveal

STAT

SEPTEMBER 5, 2024

Let’s set the table for Sunday’s presentation of the lung cancer immunotherapy trial known as HARMONi-2. Sunday’s HARMONi-2 presentation at the World Conference on Lung Cancer should provide the answers. Continue to STAT+ to read the full story…

Opinion: Tested in Africa, used in America

STAT

SEPTEMBER 18, 2024

At the recent annual International AIDS Conference, a startling presentation about the newest wonder drug in HIV prevention brought a raucous standing ovation. Lenacapavir, a novel drug given as an injection under the skin every six months, was 100% successful in preventing HIV in adolescent girls and young women in two countries in Africa.

Vaccines

RSV vaccines may be linked to small increased risk of developing Guillain-Barré syndrome, data suggest

STAT

FEBRUARY 29, 2024

At a meeting Thursday of the Advisory Committee on Immunization Practices, vaccine safety experts from the two agencies presented data that showed what appears to be an elevated rate of GBS, as the condition is called, among people who got the Pfizer vaccine, although there were also cases detected among people who got the GSK product.

Vaccines

Vaccines Immunity Immunization

Inhaled vaccines could stop Covid infections, monkey studies show

STAT

DECEMBER 20, 2023

Plus, Jason Mast pops in to give an update on Uniqure’s puzzling approach to presenting trial results. Today, we get into why Amy Abernethy is leaving Verily, and why the ongoing reckoning with AI doesn’t necessarily need the voice of Google to chime in. Read the rest…

Vaccines

Vaccines Drug Pricing Drug Development

Off-label treatment for alcohol use disorder is linked to slower liver decline, study suggests

STAT

MAY 22, 2024

The data, presented this week as an abstract at Digestive Disease Week in D.C., But a different medication, one frequently used off-label for the condition, could provide greater benefit to patients with alcohol-associated liver disease, a new study suggests.

Labelling

STAT+: Relay Therapeutics drug shows promise in early trial

STAT

SEPTEMBER 8, 2022

The results were released in an abstract at the annual meeting of the European Society of Molecular Oncology, where they will be presented in full on Sunday. Continue to STAT+ to read the full story…

STAT+: Merus drug, with immunotherapy, boosts tumor response in patients with head and neck cancer

STAT

MAY 28, 2024

But the Dutch drugmaker on Tuesday withheld additional information from the study related to the safety and durability of petosemtamab’s tumor responses, pending presentation at the annual meeting of the American Society of Clinical Oncology on June 3. Continue to STAT+ to read the full story…

The fight for control of methadone, addiction treatment’s ‘miracle molecule’

STAT

OCTOBER 20, 2023

A doctor, a patient advocate, and the most powerful figure in the methadone treatment industry presented competing visions for the future of American addiction medicine this week — a conversation that touched on stigma, patients’ rights, and a stark divide in health provider attitudes toward patients with addiction.

Opinion: Functional neurological disorder is not an appropriate diagnosis for people with long Covid

STAT

JULY 15, 2024

Long Covid — the name adopted for cases of prolonged symptoms after an acute bout of Covid-19 — is an umbrella diagnosis covering a broad range of clinical presentations and abnormal biological processes.

Millions fewer people may need statins, a new study suggests. But guidelines have yet to agree

STAT

JUNE 10, 2024

That conversation may happen less often if changes in the risk model presented by the American Heart Association in November translate into new guidelines for prescribing statins.

STAT+: Eli Lilly’s obesity drug Zepbound improved liver scarring in mid-stage MASH study

STAT

JUNE 5, 2024

of patients on placebo who achieved this outcome, the results were statistically significant, according to an abstract of data that will be presented at the annual meeting of the European Association for the Study of the Liver. from the lowest to highest doses. When compared with the 29.7% Continue to STAT+ to read the full story…

Diabetes

The state of Medicare Advantage, in one chart

STAT

JANUARY 16, 2024

Notably absent from many presentations, though, was mention of their losses on patient care, my colleague Tara Bannow reports from the conference. Hospitals want you to look here, not over there Hospital leaders took pains to draw investors’ attention to their sizable cash and investment reserves at JPM. Read the rest…

Hospitals

STAT+: In major test for prime editing, scientists successfully correct mutations in monkeys

STAT

OCTOBER 27, 2023

The results, presented at the European Society of Gene & Cell Therapy meeting in Brussels, are a major step for a technology that could transform treatment of numerous diseases. Prime Medicine said Friday it successfully used a new, ultra-versatile form of genetic surgery called prime editing to edit liver cells in monkeys.

STAT+: Pear’s shadow effect: Data from a Medicaid digital health experiment does the policy rounds

STAT

SEPTEMBER 19, 2023

In recent months, representatives of the Massachusetts state Medicaid program, MassHealth, have been presenting data suggesting reSET and reSET-O, Pear’s prescription apps that treat substance use disorder and opioid use disorder, saved the state money over a one-year period from 2021 to 2022.

STAT+: Gene therapies for deafness dredge up an old question: Do deaf people want a ‘cure’?

STAT

MAY 28, 2024

In October, he presented extraordinary data at a conference: His team had successfully enabled hearing in four congenitally deaf children using gene therapy. ’ said Shu, who is hearing and a professor at Fudan University in China. “That’s what really inspired me to think about developing a drug.”

Drug Development

Surge of respiratory disease in China triggers anxiety, but experts see likely explanation

STAT

NOVEMBER 23, 2023

But at present, a number of experts say the activity has a likely explanation: China’s population, especially its young children, probably developed significant immunological susceptibility to a range of respiratory pathogens during the years of China’s zero Covid policy.

STAT’s 2024 Diversity and Inclusion Report

STAT

OCTOBER 30, 2024

The STAT Diversity and Inclusion Committee presents STAT’s 2024 Diversity and Inclusion Report. Here, we share the self-reported gender and racial/ethnic demographics of our staff from STAT’s inception in 2015 through 2023, as well as our 2023 new hire demographics.

Opinion: It’s time for a new medical specialty in asynchronous care

STAT

OCTOBER 4, 2024

We know there is nothing more important than being fully present. A patient is sitting in front of us, explaining her symptoms: She could have difficulty breathing, stress at home, fatigue.

Vaccines

New study sparks debate about whether H5N1 virus in cows is adapted to better infect humans

STAT

JULY 8, 2024

One of the things that determines what kind of animal a given flu virus can infect is the type of receptors present on the outside of tissues that virus comes in contact with. Across the globe, different influenza viruses are constantly circulating in many different kinds of animals.

Can MRIs ensure prostate cancer screening does more good than harm?

STAT

SEPTEMBER 25, 2024

Prostate cancer presents a tricky screening challenge. Catching it early could mean dodging a painful journey with advanced cancer.

The surprising environmental cost of rapid testing, mosquito nets, and other lifesaving health products

STAT

NOVEMBER 30, 2023

Many commonly suggested ways to addressing climate change present few ethical challenges: Cut fossil fuels. Eat less meat. Don’t buy fast fashion. But what happens when products that contribute to climate change also save lives — millions of them? A new report , published on Nov.

STAT+: ASCO24: AstraZeneca won cancer’s big meeting — again. Will that help it fulfill its $80 billion ambition?

STAT

JUNE 3, 2024

That pin represents the number of years in a row that the London-based drug giant has had a presentation in the ASCO plenary, the conference’s biggest showcase for new data. This year, the company has two. Scientific credibility is great, of course. But AstraZeneca’s shareholders want something else: return on investment.

Experts say leaked messages present false link between gender-affirming care and cancer

Opinion: Diagnostic tests for rare conditions present a mathematical conundrum

Trending Sources

STAT+: Genentech, a biotech with a storied past, confronts new turbulence in the present

STAT+: Recursion presents mixed data on lead AI-derived drug candidate for potentially fatal brain condition

Opinion: Racism infects neuroscience’s past and present. What about its future?

STAT+: Truvian presents data for its desktop blood-testing device in a field still in Theranos’s shadow

STAT+: From Epic to FDA, all the leaders presenting at HHS’ invite-only AI in health care event

Opioid cravings were reduced by anti-obesity drug in small study

STAT+: At ASCO, AstraZeneca says its CAR-T therapy shrank solid liver tumors in early trial

STAT+: Nvidia says a biological revolution is happening now. But is it?

STAT+: Roche drug slashes recurrence, death risk in lung cancer that afflicts younger patients

STAT+: Under-the-skin injection of Eisai’s Leqembi is as effective as IV infusion, new Alzheimer’s data show

Palliative care for cancer patients is found to be as effective given virtually as in person

STAT+: Could kidney transplant patients be spared a lifetime of immunosuppressants?

Scientists document first-ever transmitted Alzheimer’s cases, tied to no-longer-used medical procedure

STAT+: ResMed CEO on how wearables, GLP-1s will impact sleep apnea device sales

Global health leader critiques ‘ineptitude’ of U.S. response to bird flu outbreak among cows

Dietary experts advise skipping guidelines on ultra-processed foods — for now

STAT+: With an old approach but new energy, ADCs take center stage as promising cancer treatments

SAEM Clinical Images Series: Purple Finger

Opinion: Pumping milk at JPM was a nightmare. It’s part of a bigger problem in the industry

Male birth control research wins audience over at STAT Madness event

STAT+: Summit Therapeutics vs. Merck: Prepping for a big lung cancer study reveal

Opinion: Tested in Africa, used in America

RSV vaccines may be linked to small increased risk of developing Guillain-Barré syndrome, data suggest

Inhaled vaccines could stop Covid infections, monkey studies show

Off-label treatment for alcohol use disorder is linked to slower liver decline, study suggests

STAT+: Relay Therapeutics drug shows promise in early trial

STAT+: Merus drug, with immunotherapy, boosts tumor response in patients with head and neck cancer

The fight for control of methadone, addiction treatment’s ‘miracle molecule’

Opinion: Functional neurological disorder is not an appropriate diagnosis for people with long Covid

Millions fewer people may need statins, a new study suggests. But guidelines have yet to agree

STAT+: Eli Lilly’s obesity drug Zepbound improved liver scarring in mid-stage MASH study

The state of Medicare Advantage, in one chart

STAT+: In major test for prime editing, scientists successfully correct mutations in monkeys

STAT+: Pear’s shadow effect: Data from a Medicaid digital health experiment does the policy rounds

STAT+: Gene therapies for deafness dredge up an old question: Do deaf people want a ‘cure’?

Surge of respiratory disease in China triggers anxiety, but experts see likely explanation

STAT’s 2024 Diversity and Inclusion Report

Opinion: It’s time for a new medical specialty in asynchronous care

New study sparks debate about whether H5N1 virus in cows is adapted to better infect humans

Can MRIs ensure prostate cancer screening does more good than harm?

The surprising environmental cost of rapid testing, mosquito nets, and other lifesaving health products

STAT+: ASCO24: AstraZeneca won cancer’s big meeting — again. Will that help it fulfill its $80 billion ambition?

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