This site uses cookies to improve your experience. To help us insure we adhere to various privacy regulations, please select your country/region of residence. If you do not select a country, we will assume you are from the United States. Select your Cookie Settings or view our Privacy Policy and Terms of Use.
Cookie Settings
Cookies and similar technologies are used on this website for proper function of the website, for tracking performance analytics and for marketing purposes. We and some of our third-party providers may use cookie data for various purposes. Please review the cookie settings below and choose your preference.
Used for the proper function of the website
Used for monitoring website traffic and interactions
Cookie Settings
Cookies and similar technologies are used on this website for proper function of the website, for tracking performance analytics and for marketing purposes. We and some of our third-party providers may use cookie data for various purposes. Please review the cookie settings below and choose your preference.
Strictly Necessary: Used for the proper function of the website
Performance/Analytics: Used for monitoring website traffic and interactions
Subscribe on iTunes , Android , or Stitcher The label of “penicillin allergic” usually sticks to a patient’s medical record forever. A 50 y/o male with an SSTI had an unknown allergy to penicillin, received a single dose of ceftriaxone in the ED and was then switched to piperacillin-tazobactam as an inpatient.
In this episode, I’ll discuss how to predict the pharmacotherapy needs of your patient and team during an inpatient medical emergency. This is when you do regular pharmacist things like drawing up and labeling medications, and calculating doses. This work is valuable because it frees a nurse up to be hands-on with a patient.
Back in episode 473 , I talked about the evidence behind the discrepancy between the labeled dose and the analgesic ceiling dose of IV ketorolac. If you like this post, check out my book – A Pharmacist’s Guide to Inpatient Medical Emergencies: How to respond to code blue, rapid response calls, and other medical emergencies. <–
The US labeling states: Anti-FXa activity adjusted for exposure to apixaban was similar across renal function categories. Using inverse probability of treatment weighting analysis, the US labeling recommendation of apixaban 5 mg was associated with a higher risk of bleeding at an incidence rate 4.9 or greater. mg twice daily.
The US labeling states: Anti-FXa activity adjusted for exposure to apixaban was similar across renal function categories. Using inverse probability of treatment weighting analysis, the US labeling recommendation of apixaban 5 mg was associated with a higher risk of bleeding at an incidence rate 4.9 or greater. mg twice daily.
By predicting this need in advance, calculating doses, preparing and labeling syringes, the pharmacist can also enhance medication safety and free up the rest of the care team to remain hands-on with the patient ensuring adequate pre-oxygenation, IV access, and supportive care.
Authors recently published in New England Journal of Medicine an open label multi center trial looking at early vs later anticoagulation in patients with afib who had an ischemic stroke. To access my free download area with 20 different resources to help you in your practice, go to pharmacyjoe.com/free.
If using this off-label strategy, give preference to the preservative-free version of IV tranexamic acid due to the potential adverse effects of nebulized preservatives. There were no side effects noted in either group throughout the follow-up period. A reduced hemoptysis recurrence rate was noted at the 1-year follow-up (P =.009
If using this off-label strategy, give preference to the preservative-free version of IV tranexamic acid due to the potential adverse effects of nebulized preservatives. There were no side effects noted in either group throughout the follow-up period. A reduced hemoptysis recurrence rate was noted at the 1-year follow-up (P =.009
However, the origins of these so called evidence practices, it all just started from off-label use too. Summary In the face of a shortage, the fundamental roles of pharmacists in both inpatient and outpatient settings should be prioritized before expanding into other services.
Subscribe on iTunes , Android , or Stitcher Whether torsemide improves patient Heart Failure (HF) symptoms and quality of life better than furosemide is a matter of debate among clinicians, and a group of authors recently published an open-label, multi-center, randomized trial in the journal Circulation in an effort to resolve this question.
If you like this post, check out my book – A Pharmacist’s Guide to Inpatient Medical Emergencies: How to respond to code blue, rapid response calls, and other medical emergencies. <– To access my free download area with 20 different resources to help you in your practice, go to pharmacyjoe.com/free.
If you like this post, check out my book – A Pharmacist’s Guide to Inpatient Medical Emergencies: How to respond to code blue, rapid response calls, and other medical emergencies. <– To access my free download area with 20 different resources to help you in your practice, go to pharmacyjoe.com/free.
This was an open label randomized trial of 110 patients who were evenly split between IV and nebulized tranexamic acid groups. If you like this post, check out my book – A Pharmacist’s Guide to Inpatient Medical Emergencies: How to respond to code blue, rapid response calls, and other medical emergencies. <–
Authors recently published in New England Journal of Medicine an open label multi center trial looking at early vs later anticoagulation in patients with afib who had an ischemic stroke. To access my free download area with 20 different resources to help you in your practice, go to pharmacyjoe.com/free.
Such a recommendation, even though it is labeled as weak and based on very low-quality evidence is likely to make its way into hospital protocol in the form of automatically discontinuing a C diff test for a patient with recent laxative use. Members of my Hospital Pharmacy Academy have access to practical trainings on C.
Provide infusions to the nurse in the most ready-to-use form possible including obtaining the smart pump, IV tubing, spiking the bag and priming the tubing, and labeling the lines. Establish a plan for ongoing sedation with the provider. To get immediate access, go to pharmacyjoe.com/academy.
This was a multi-center trial that randomized over 800 hemodynamically unstable potential heart donors within 24 hours after declaration of death according to neurologic criteria to either an open-label infusion of intravenous levothyroxine at 30 mcg/hr or saline placebo.
This was a multi-center trial that randomized over 800 hemodynamically unstable potential heart donors within 24 hours after declaration of death according to neurologic criteria to either an open-label infusion of intravenous levothyroxine at 30 mcg/hr or saline placebo.
Provide infusions to the nurse in the most ready-to-use form possible including obtaining the smart pump, IV tubing, spiking the bag and priming the tubing, and labeling the lines. Establish a plan for ongoing sedation with the provider. To get immediate access, go to pharmacyjoe.com/academy.
The ACORN randomized trial sought to compare rates of AKI and neurotoxicity in patients hospitalized with acute infection who were randomized 1:1 in an open-label fashion to receive either piperacillin-tazobactam or cefepime for gram-negative coverage. However, other studies have examined a link between increased neurotoxicity with cefepime.
The ACORN randomized trial sought to compare rates of AKI and neurotoxicity in patients hospitalized with acute infection who were randomized 1:1 in an open-label fashion to receive either piperacillin-tazobactam or cefepime for gram-negative coverage. However, other studies have examined a link between increased neurotoxicity with cefepime.
The study was an open-label, multicenter, randomized controlled trial in 9 Australian Emergency Departments. If you like this post, check outmy book A Pharmacists Guide to Inpatient Medical Emergencies: How to respond to code blue, rapid response calls, and other medical emergencies. <–
Back in episode 473 , I talked about the evidence behind the discrepancy between the labeled dose and the analgesic ceiling dose of IV ketorolac. If you like this post, check out my book – A Pharmacist’s Guide to Inpatient Medical Emergencies: How to respond to code blue, rapid response calls, and other medical emergencies. <–
If using this off-label strategy, give preference to the preservative-free version of IV tranexamic acid due to the potential adverse effects of nebulized preservatives. There were no side effects noted in either group throughout the follow-up period. A reduced hemoptysis recurrence rate was noted at the 1-year follow-up (P =.009
To improve the data available in this patient population, investigators in Brazil completed a multicenter, randomized, open-label, noninferiority trial with 1000 patients comparing rivaroxaban with warfarin for patients with atrial fibrillation and a bioprosthetic mitral valve.
The RECOVERY Trial, which is a randomized, controlled, open-label trial, underway at 177 hospitals recently published results of using colchicine in patients admitted to hospital with COVID-19. Patients received either placebo or colchicine 1 mg oral load followed by 0.5
If you like this post, check out my book – A Pharmacist’s Guide to Inpatient Medical Emergencies: How to respond to code blue, rapid response calls, and other medical emergencies. <– To access my free download area with 20 different resources to help you in your practice, go to pharmacyjoe.com/free.
Recently published in Lancet was a non-inferiority, open-label, multicentre, randomized trial that sought to clarify the safety of early antibiotic discontinuation in hematology patients with fever of unknown origin during chemotherapy-induced neutropenia.
Milrinone labeling suggests a renal dose adjustment for patients with creatinine clearance between 10 and 50 mL/min but has no recommendations or data available for patients with ESRD or who are receiving CRRT.
This was an open label randomized trial of 110 patients who were evenly split between IV and nebulized tranexamic acid groups. If you like this post, check out my book – A Pharmacist’s Guide to Inpatient Medical Emergencies: How to respond to code blue, rapid response calls, and other medical emergencies. <–
By predicting this need in advance, calculating doses, preparing and labeling syringes, the pharmacist can also enhance medication safety and free up the rest of the care team to remain hands-on with the patient ensuring adequate pre-oxygenation, IV access, and supportive care.
Provide infusions to the nurse in the most ready-to-use form possible including obtaining the smart pump, IV tubing, spiking the bag and priming the tubing, and labeling the lines. Establish a plan for ongoing sedation with the provider. To get immediate access, go to pharmacyjoe.com/academy.
Such a recommendation, even though it is labeled as weak and based on very low-quality evidence is likely to make its way into hospital protocol in the form of automatically discontinuing a C diff test for a patient with recent laxative use. Members of my Hospital Pharmacy Academy have access to practical trainings on C.
Secondary outcome measures were numerically favorable for haloperidol including the need for open-label haloperidol or other antipsychotics, and self-extubation or invasive device removal. However none of these secondary outcomes reached statistical significance.
Secondary outcome measures were numerically favorable for haloperidol including the need for open-label haloperidol or other antipsychotics, and self-extubation or invasive device removal. However none of these secondary outcomes reached statistical significance.
Back in episode 473 , I talked about the evidence behind the discrepancy between the labeled dose and the analgesic ceiling dose of IV ketorolac. If you like this post, check out my book – A Pharmacist’s Guide to Inpatient Medical Emergencies: How to respond to code blue, rapid response calls, and other medical emergencies. <–
A group of authors recently published in NEJM the results of a randomized, multicenter, open-label, parallel-group trial in the UK examining this issue. If you like this post, check out my book – A Pharmacist’s Guide to Inpatient Medical Emergencies: How to respond to code blue, rapid response calls, and other medical emergencies. <–
A group of authors from Sorbonne University in Paris, France conducted a randomized open label multicenter trial to examine whether an 8 day course of therapy for Pseudomonas VAP (PA-VAP) could be non-inferior to a 15 day course. 25 of 98 patients in the 15-day group and 31 of 88 patients in the 8-day group reached the composite endpoint.
This was a multicenter, open-label, noninferiority randomized clinical trial of 206 ICU patients with VAP. If you like this post, check out my book – A Pharmacist’s Guide to Inpatient Medical Emergencies: How to respond to code blue, rapid response calls, and other medical emergencies. <–
The study was a prospective, randomized, open-label, parallel assignment, single-center clinical trial of 801 patients. If you like this post, check out my book – A Pharmacist’s Guide to Inpatient Medical Emergencies: How to respond to code blue, rapid response calls, and other medical emergencies. <–
Recently published in Lancet was a non-inferiority, open-label, multicentre, randomized trial that sought to clarify the safety of early antibiotic discontinuation in hematology patients with fever of unknown origin during chemotherapy-induced neutropenia.
Milrinone labeling suggests a renal dose adjustment for patients with creatinine clearance between 10 and 50 mL/min but has no recommendations or data available for patients with ESRD or who are receiving CRRT.
By predicting this need in advance, calculating doses, preparing and labeling syringes, the pharmacist can also enhance medication safety and free up the rest of the care team to remain hands-on with the patient ensuring adequate pre-oxygenation, IV access, and supportive care.
We organize all of the trending information in your field so you don't have to. Join 11,000+ users and stay up to date on the latest articles your peers are reading.
You know about us, now we want to get to know you!
Let's personalize your content
Let's get even more personalized
We recognize your account from another site in our network, please click 'Send Email' below to continue with verifying your account and setting a password.
Let's personalize your content