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STAT+: Dreams of cancer vaccines are becoming more real. Here are 9 scientists making it happenĀ 

STAT

Vaccines are the original immunotherapy, in the view of Ryan Sullivan, a cancer immunotherapy researcher and oncologist at Mass General Cancer Center. But many other modes of immunotherapy for cancer were approved first — checkpoint blockade drugs like Keytruda and engineered immune cell therapies like Yescarta.

Vaccines 355
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Opinion: The next frontier in biomedicine: AI models of the human immune system

STAT

If the Covid-19 pandemic has shown us one thing, it is how little we really know about how the human immune system works. Decoding and harnessing the power of the human immune system is one of the great frontiers of biomedicine. Read the rest…

Immunity 340
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STAT+: Cancer vaccines gain momentum, after years of disappointing results

STAT

SAN DIEGO — Cancer vaccines have traveled a potholed road over the last decade. But as researchers from different companies and academic institutions presented promising early data at the American Association for Cancer Research annual meeting in San Diego this week, experts said there’s a collective feeling of turning a corner.

Vaccines 362
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RSV vaccines may be linked to small increased risk of developing Guillain-BarrƩ syndrome, data suggest

STAT

The new vaccines that protect older adults against respiratory syncytial virus, or RSV, may be linked to a small increased risk of developing Guillain-Barré syndrome, new data from the Centers for Disease Control and Prevention and the Food and Drug Administration suggest. Read the rest…

Vaccines 356
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Flu vaccine offering decent levels of protection this winter, new data show

STAT

Flu vaccine appears to be offering reasonable levels of protection this winter, with particularly strong levels in children, new data from the Centers for Disease Control and Prevention suggest. Read the rest…

Vaccines 276
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Temperature-stable tuberculosis vaccine induces immune response

European Pharmaceutical Review

The first clinical trial of any subunit tuberculosis (TB) vaccine in a temperature-stable form has found that ID93+GLA-SE, a freeze-dried vaccine, was safe. The recombinant subunit vaccine is made from four proteins of Mycobacterium tuberculosis bacteria combined with GLA-SE, an immune-stimulating adjuvant.

Immunity 103
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Chikungunya vaccine demonstrates 99 percent immune response

European Pharmaceutical Review

If approved, VLA1553 could become the first licensed chikungunya vaccine” A single vaccination of VLA1553 has been shown to produce neutralising antibody levels, thought to protect against chikungunya disease in 99 percent of Phase III trial participants. What did the chikungunya vaccine study results show?

Immunity 105