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RVAC and University of Pennsylvania to develop mRNA vaccines

Pharmaceutical Technology

The collaboration, under a sponsored research agreement, will focus on mRNA vaccines that can help in modulating the normal immune response of the body for the treatment of certain autoimmune diseases as well as allergic conditions. Cell & Gene Therapy coverage on Pharmaceutical Technology is supported by Cytiva.

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Kite and Daiichi Sankyo update cell therapy licensing agreement

Pharmaceutical Technology

Directed against a cell membrane protein called CD19, Yescarta uses the immune system of the patient to destroy cancer. By downloading this Whitepaper, you acknowledge that we may share your information with our white paper partners/sponsors who may contact you directly with information on their products and services.

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Hospital Universitario and Josep Carreras develop cell therapy for leukaemia

Pharmaceutical Technology

CAR-T therapies are based on the patient’s immune cell modification and can express artificial chimeric receptors that can identify and remove tumour cells. This therapy is expected to be an improvement over CAR-T in relapsed patients, especially those who have less number of normal T lymphocytes.

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Boehringer Ingelheim partners with 3T Biosciences for cancer therapies

Pharmaceutical Technology

The collaboration will combine 3T Biosciences’ 3T- T-Cell Receptor Antigen and Cross-Reactivity Engine (TRACE) discovery platform with Boehringer Ingelheim’s two-pronged research strategy combining compounds that are directed towards cancer cells and target immune cells.

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OPQ’s 2023 Annual Report: an Upbeat Review of CDER’s Quality Efforts

FDA Law Blog: Biosimilars

It also noted that last year, FDA hosted a two-day public workshop and published a white paper on the regulatory framework for Artificial Intelligence in drug manufacturing, in addition to other efforts. Like many of us, OPQ seems intent on trying to keep up with how technology can/will impact pharmaceutical quality.

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NICE recommends Kite’s CAR-T therapy to treat lymphoma

Pharmaceutical Technology

It takes own immune cells of a patient and modifies them to attach and destroy cancer cells. The new CAR-T therapy will be given as a one-off intravenous infusion. Previously, it was available through the Cancer Drugs Fund (CDF).

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Eucure Biopharma and Chipscreen NewWay sign licence deal for YH008

Pharmaceutical Technology

It was engineered with an Fc-silent IgG1 isotype to avoid activation of Fc-receptor-mediated non-specific immune. The bispecific antibody was found to conditionally activate the immune pathway in the tumour microenvironment in vitro and in vivo trials.