STAT

OCTOBER 29, 2024

But many other modes of immunotherapy for cancer were approved first — checkpoint blockade drugs like Keytruda and engineered immune cell therapies like Yescarta. Cancer vaccines may also be able to help train the immune system to recognize and kill cancers related to viruses like HPV.

Vaccines 351

Vaccines Immunity Immunization Drug Development 351

Express Pharma

JUNE 20, 2023

The vaccine efforts of the COVID-19 pandemic highlighted our knowledge about gaps in the immune system. Reductionist systems, such as genetically identical inbred mice, have long been the choice for immunology research, which focuses on studying the cells, tissues, and organs that make up the immune system.

Immunity 102

Immunity Immunization Vaccines Hospitals 102

pharmaphorum

JULY 26, 2021

While there are plenty of tests already available that can give a yes/no reading of whether antibodies are present, the Chembio test measures the level of antibodies as well, so can tell whether a patient is likely to be protected against the coronavirus. The post Rapid COVID immune status test launched in UK, Ireland appeared first on.

Immunity 137

Immunity Immunization Vaccines 137

STAT

FEBRUARY 29, 2024

At a meeting Thursday of the Advisory Committee on Immunization Practices, vaccine safety experts from the two agencies presented data that showed what appears to be an elevated rate of GBS, as the condition is called, among people who got the Pfizer vaccine, although there were also cases detected among people who got the GSK product.

Vaccines 347

Vaccines Immunity Immunization 347

pharmaphorum

NOVEMBER 4, 2021

While still preliminary, the experience with the two patients back up Talaris’ hope that giving a one-shot dose of FCR001 the day after an organ transplant could stimulate immune tolerance in the recipient, and avoid the side effects of current drug treatments such as infections, heart disease, and some forms of cancer.

Immunity 98

Immunity Immunization 98

Pharmacy Joe

OCTOBER 18, 2023

In this episode, I’ll discuss why hypokalemia can result from digoxin immune fab fragment administration. With the administration of antidote therapy with digoxin immune fab fragments, the function of the sodium-potassium ATPase pump is restored.

Immunity 52

Immunity Immunization Hospitals Inpatient 52

Pharmacy Joe

OCTOBER 18, 2023

In this episode, I’ll discuss why hypokalemia can result from digoxin immune fab fragment administration. With the administration of antidote therapy with digoxin immune fab fragments, the function of the sodium-potassium ATPase pump is restored.

Immunity 52

Immunity Immunization Hospitals Inpatient 52

STAT

FEBRUARY 29, 2024

The vaccine effectiveness estimates, which showed unusually robust protection of children against influenza B viruses but more modest protection of people aged 65 and older against influenza A viruses, were presented Wednesday at a meeting of the CDC’s expert vaccine panel, the Advisory Committee on Immunization Practices.

Vaccines 266

Vaccines Immunity Immunization 266

STAT

APRIL 10, 2024

But as researchers from different companies and academic institutions presented promising early data at the American Association for Cancer Research annual meeting in San Diego this week, experts said there’s a collective feeling of turning a corner. SAN DIEGO — Cancer vaccines have traveled a potholed road over the last decade.

Vaccines 362

Vaccines Immunity Immunization Drug Development 362

ALiEM - Pharm Pearls

OCTOBER 11, 2024

A 76-year-old female presented with a lingering cough and an oral lesion to the left lower cheek. On the day of presentation, she developed a painful, intermittently bleeding “blood blister” to the left lower cheek that had increased in size, as well as new red spots on her arms and legs. Physical Exam Vitals : 98.3°F; Plt 6, WBC 10.3

Immunity 152

Immunity Immunization 152

pharmaphorum

AUGUST 2, 2022

In May, another amyloid targeting drug for Alzheimer’s disease – AC Immune and Roche’s crenezumab – missed the mark in another clinical trial and looked destined for the scrap heap like so many drugs in the class before it. The post AC Immune tries to resurrect crenezumab with new data delve appeared first on.

Immunity 52

Immunity Immunization 52

STAT

FEBRUARY 22, 2023

The data were presented Wednesday to the Advisory Committee on Immunization Policy, which advises the Centers for Disease Control and Prevention. Read the rest…

Immunity 246

Immunity Immunization Hospitals Vaccines 246

STAT

OCTOBER 8, 2024

So join us as we hoist the ever-present cup of stimulation — our choice today is coconut rum — and attack the fast-growing to-do list. Lots of sunshine and clear blue skies are once again enveloping the Pharmalot campus, where the official mascots are bounding about the grounds in search of creatures to annoy. ” A U.S.

Compounding 204

Compounding Compounding Pharmacies Vaccines Immunity 204

STAT

DECEMBER 10, 2022

NEW ORLEANS — Researchers had hoped in recent years that a protein called GPRC5D might offer a new way to get the immune system to hunt down and destroy multiple myeloma cells. Now, the results of a Phase 2 study on a bispecific antibody targeting this protein offers confirmation.

Immunization 263

Immunization Immunity 263

European Pharmaceutical Review

AUGUST 25, 2022

This strategy has failed to gain a foothold in the past as the patient’s immune system interferes, destroying the unprotected oncolytic viruses. 7 Studies also sought to modify oncolytic viruses with additional genes that more efficiently recruit the patient’s immune system to target tumour cells. suppressing activity.

Immunity 111

Immunity Immunization Chemotherapy Packaging 111

PharmaTech

APRIL 2, 2024

Experts believe it is likely cancer cells are more common in the body than previously thought, but typically caught early and removed in the body’s cancer-immune cycle. When the system is in good working order (and protecting us), dead cancer cells release neoantigens.

Immunity 52

Immunity Immunization 52

World Pharma News

OCTOBER 9, 2023

NYSE: PFE) will present data across its infectious disease portfolio at the upcoming IDWeek 2023 held in Boston from October 11-15, 2023. Pfizer Inc. Data from 45 abstracts will highlight the advances Pfizer is making in helping prevent and treat certain infectious diseases, particularly respiratory illnesses.

Vaccines 85

Vaccines Immunization Immunity 85

Pharma Mirror

FEBRUARY 18, 2021

A novel approach for ensuring the virtually unlimited production of QS-21, the ‘Gold Standard’ adjuvant for improving vaccine efficacy, will be the subject of an upcoming presentation at the BIO CEO & Investor Digital Conference, starting February 16.

Immunity 52

Immunity Immunization Vaccines 52

Pharmacy Joe

FEBRUARY 13, 2022

In this episode, I’ll discuss when rabies immune globulin is indicated. Episode 687: How to decide when to give rabies immune globulin? Subscribe on iTunes , Android , or Stitcher Rabies immune globulin (RIG) administration is part of successful rabies post-exposure prophylaxis. appeared first on Pharmacy Joe.

Immunity 40

Immunity Immunization Vaccines Inpatient 40

pharmaphorum

APRIL 4, 2022

In particular, the findings suggest that disruption to innate immunity – the first line of defence against pathogens – as well as overly aggressive activity of white blood cells in the central nervous system called microglia. ” The post Study uncovers new Alzheimer’s genes, links to immune disruption appeared first on.

Immunity 52

Immunity Immunization 52

Pharmacy Joe

SEPTEMBER 23, 2021

In this episode, I’ll discuss a possible syndrome that might herald vaccine-induced immune thrombotic thrombocytopenia. Episode 646: Does vaccine-induced immune thrombotic thrombocytopenia have a “pre-VITT syndrome” ? All 11 patients presented with severe headache 5 to 18 days after adenovirus vector vaccination.

Immunity 40

Immunity Immunization Vaccines Inpatient 40

ALiEM - Pharm Pearls

OCTOBER 25, 2024

A 64-year-old male with a history of bipolar 1 disorder, PTSD, anxiety, depression, obsessive-compulsive disorder, GERD, and HTN presented to the ED with the chief complaint of foreign body and self-injury. Numerous linear metallic foreign bodies are present throughout the right forearm; several new foreign bodies are noted.

Vaccines 177

Vaccines Immunity Immunization 177

Pharmacy Joe

FEBRUARY 10, 2021

In this episode, I’ll discuss why hypokalemia can result from digoxin immune fab fragment administration. With the administration of antidote therapy with digoxin immune fab fragments, the function of the sodium-potassium ATPase pump is restored.

Immunity 40

Immunity Immunization Hospitals Inpatient 40

ALiEM - Pharm Pearls

OCTOBER 21, 2024

A 5-year-old generally healthy fully immunized boy presented to the ED with worsening left ear redness, swelling, and tenderness that his family noticed the day before presentation. His family had also recently noticed an abrasion over that ear.

Medical Schools 169

Medical Schools Immunity Immunization 169

Pharma Times

APRIL 17, 2023

Efti’s targeting activation of antigen-presenting cells delivers an adaptive immunity to fight cancer

Immunity 104

Immunity Immunization 104

Express Pharma

NOVEMBER 13, 2024

Bristol Myers Squibb and Cabaletta Bio are set to present promising Phase I data on CD19-directed CAR T therapies for severe, refractory lupus at the American College of Rheumatology 2024. Edits made by EP News Bureau The post CAR T cell therapies to promote drug-free remission in lupus care appeared first on Express Pharma.

Immunity 87

Immunity Immunization 87

European Pharmaceutical Review

DECEMBER 12, 2023

He discusses why NK cell therapy’s ability to generate ‘synthetic immunity’ in the body means this modality holds potential as an anti-cancer treatment. We specialise in the development of new cutting-edge immunotherapies , based on the use of therapeutic antibodies capable of activating the immune system to fight cancer.

Immunity 124

Immunity Immunization Chemotherapy Pharmaceutical Companies 124

Pharmafile

APRIL 18, 2023

read more

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Immunity Immunization Vaccines 40

Pharmacy Times

MAY 6, 2024

Merck presented results from the STRIDE-10 phase 3 trial at the 34th European Society of Clinical Microbiology and Infectious Diseases in Barcelona, Spain.

Immunity 26

Immunity Immunization 26

Express Pharma

SEPTEMBER 26, 2023

Their research, conducted in collaboration with scientists from Dayanand Medical College and Hospital in Punjab and the CSIR-Institute for Himalayan Bioresource Technology in Himachal Pradesh, presents a novel, faster, and more effective approach to producing vaccines for challenging infectious diseases.

Vaccines 102

Vaccines Immunity Immunization Hospitals 102

European Pharmaceutical Review

SEPTEMBER 20, 2023

Results of a Phase I/II study has revealed that a booster dose of a novel, self-amplifying messenger RNA (sa-mRNA) COVID-19 vaccine induces a robust, broadly cross-reactive, and durable immune response in adults. All three vaccines induced robust neutralising immune response against the D614G variant at Day 29.

Vaccines 98

Vaccines Immunity Immunization 98

Pharmafile

APRIL 3, 2023

aVaxziPen, a biotech company focusing on the development of a novel needle-free vaccine delivery platform, has announced that it will present data at the World Vaccine Congress (WVC) in Washington, US. read more

Vaccines 72

Vaccines Immunity Immunization 72

Pharmacy Times

OCTOBER 3, 2023

In addition to the annual flu vaccines, COVID-19 boosters and RSV vaccines present new opportunities for pharmacists to advise patients.

Immunity 26

Immunity Immunization Vaccines 26

ALiEM - Pharm Pearls

DECEMBER 18, 2023

A 19-year-old female with a past medical history of epilepsy presented to the emergency department for evaluation of rash and fever. Two days prior to presentation she began to experience fevers with a Tmax of 103°F. Diagnosis can be extremely challenging due to the variability in clinical presentation. Int J Mol Sci.

Immunity 177

Immunity Immunization 177

Pharmaceutical Technology

JUNE 6, 2023

PF-06835375 is a biologic commercialized by Pfizer, with a leading Phase II program in Idiopathic Thrombocytopenic Purpura (Immune Thrombocytopenic Purpura). The drug’s revenue forecasts along with estimated costs are used to measure the value of an investment opportunity in that drug, otherwise known as net present value (NPV).

Immunity 40

Immunity Immunization Biosimilars Hospitals 40

Express Pharma

AUGUST 27, 2024

This method is time-efficient and expected to present all antigens, mimicking natural infection. Codon deoptimization involves reducing the frequency of underrepresented codon pairs without changing amino acid sequences, resulting in a highly efficient virus attenuation strategy.

Vaccines 89

Vaccines Immunity Immunization Communication 89

Express Pharma

JULY 12, 2024

In the context of modern medicine, messenger RNA (mRNA) serves as the hacker, carrying genetic instructions to produce specific proteins within cells that can induce desired immune responses or sequester maladaptive cellular elements.

Immunity 86

Immunity Immunization Compounding Vaccines 86