STAT

MARCH 27, 2025

And while the meeting took place two days after a report that the department had tapped vaccine critic David Geier to conduct a study looking for a link between immunizations and autism, the Louisiana senator said that issue did not come up.      Read the rest…

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STAT

JANUARY 18, 2024

New research published Thursday in Science has identified proteins present in the blood of people with long Covid that could point the way to a much-needed diagnostic test and possibly to future therapeutic targets.

Immunity 363

Immunity Immunization 363

STAT

NOVEMBER 24, 2023

The evidence presented to the WHO team pointed to what’s sometimes called an immunity gap that was created by the pandemic. But a rapidly organized meeting Thursday between the World Health Organization and health officials in China assuaged much of that concern.

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Immunity Immunization 364

STAT

JANUARY 22, 2025

Immune checkpoint inhibitors, drugs that can help make the immune system recognize and destroy cancer more aggressively, are one of the most important medicines in cancer treatment today.

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Immunity Immunization Compounding Drug Development 361

STAT

MARCH 21, 2024

This “summer of discovery,” as McKenna called it, brought him back to the immune system. McKenna discussed possibilities with his teenagers and Prometheus’ chief scientific officer.

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Immunity Immunization 332

STAT

OCTOBER 25, 2022

That’s the premise behind Normunity, which launched Tuesday with $65 million from investors to develop a suite of drugs that it dubs “immune normalizers” to help restore the natural ability of the immune system’s T cells to infiltrate and destroy tumors.

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Immunity Immunization 246

STAT

MARCH 22, 2024

The Food and Drug Administration on Friday authorized a new antibody to protect immunocompromised individuals against Covid-19.    The drug, known as Pemgarda and marketed by the biotech Invivyd, is the first such drug to become available since the agency pulled AstraZeneca’s Evusheld off the market in January 2023.

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Immunity Immunization Drug Development 364

STAT

MAY 10, 2023

Prior research has shown that people with obesity have deficiencies in their “natural killer” cells, or NK cells — immune cells that help in combating cancer. A new small study suggests they may also be useful in fighting cancer.

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Immunity Immunization Diabetes 254

STAT

JANUARY 17, 2025

Today, we see insulin-producing cells survive in a human body without triggering an immune rejection, and have some big news from CMS. Hope those of you who were in San Francisco for J.P. Morgan are resting, recovering, and not coping with any quad-emic strains. Read the rest…

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STAT

OCTOBER 10, 2023

LONDON — In this case, it was neither the chicken nor the egg that came first. Rather, it started with some specially engineered cells in a lab. The chicken cells had had their genomes edited, not to correct a faulty mutation, but in an effort to blunt the bird flu virus.

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Immunity Immunization 360

STAT

OCTOBER 25, 2023

Alison Buttenheim was floored by a sign she saw in her doctor’s office when she went to get the first jab of the two-dose shingles vaccine to protect her against painful flare-ups of varicella zoster. “Medicare patients cannot receive Tdap or zoster vaccines here. They need to obtain [them] at their pharmacy.

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Vaccines Immunity Immunization 363

STAT

APRIL 4, 2025

This time around, we note that  Immuneering hired Igor Matushansky as chief medical officer. Don’t be shy. Everyone wants to know who is coming and going. And here is our regular feature in which we highlight a different person each week.

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Immunity Immunization 229

PharmaVoice

SEPTEMBER 11, 2023

After dropping its neuroscience program earlier this year, the clinical-stage oncology company is doubling down on a candidate targeting the MAPK pathway.

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Immunity Immunization 246

STAT

AUGUST 16, 2024

Pfizer and BioNTech said Friday that their combined mRNA vaccine candidate against influenza and Covid-19 showed a lower immune response against one type of influenza, influenza B, in a Phase 3 trial, a setback for the vaccine. ” Continue to STAT+ to read the full story…

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Vaccines Immunity Immunization 350

STAT

FEBRUARY 21, 2024

Alison Sbrana was in the belly of an opera when her life changed. Down in the pit, surrounded by fellow orchestra members, she’d been straining to play her flute for half the show. As performers overhead enveloped the audience in arias, Sbrana felt like the Hulk was pulling on the tendons in the right side of her neck.

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Immunity Immunization 364

Pharma Times

MAY 2, 2024

Bacteroides fragilis in the gut improves immunity and immunotherapy treatment responses

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Immunity Immunization 146

Pharma Times

MAY 30, 2024

Affecting the immune system, various forms of SCID are estimated to affect one in 75,000 to 100,000 newborns

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Immunity Immunization Hospitals 142

STAT

JANUARY 24, 2024

This happens to people whose immune systems are compromised, whether through disease or treatment, leaving them vulnerable to infections that last weeks, months, or, in one known case, a year.

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Immunity Immunization 363

STAT

MAY 8, 2024

Tolerance is the holy grail in calming autoimmune disease, a truce in the immune system’s faulty battle against the body’s own fabric. In type 1 diabetes, immune fighters attack beta cells in the pancreas that produce insulin, the hormone that controls glucose levels in the blood.

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Diabetes Immunity Immunization 326

PharmaVoice

JULY 14, 2022

The company’s chief medical officer discusses its lead candidate and how it fits into wider oncology trends.

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Immunity Immunization 265

STAT

FEBRUARY 21, 2024

There’s symptom management, hopeful periods of remission often followed by relapses, but rarely a lasting fix for the way their immune system attacks healthy cells. If the immune system is an army, then those with conditions like lupus, multiple sclerosis, or rheumatoid arthritis are often fighting a never-ending war of friendly fire.

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Immunity Immunization 363

STAT

SEPTEMBER 16, 2022

Rheumatology — the study of immune-system-driven diseases of the bones, joints, muscles, and in-betweens — has inherited plenty of hand-me-downs from cancer research. For example, there are ways of squelching an immune system in order to shrink certain kinds of cancerous tumors.

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Immunity Immunization 342

STAT

OCTOBER 14, 2024

Companies that are developing new medicines for autoimmune conditions, as well as other immune system disorders, have brought in more money and closed more deals so far this year than most other areas, including the cardiometabolic field, data from investment bank Oppenheimer show.

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Immunity Immunization Drug Development 363

STAT

MAY 22, 2024

Biogen is joining the industry’s fervor over immune and inflammatory disease drug development with a new acquisition. HI-Bio, which is based in San Francisco, is developing therapies for immune-mediated diseases like primary membranous nephropathy and IgA nephropathy, both of which impact kidney function. The Cambridge, Mass.,

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Immunity Immunization Drug Development 330

STAT

MARCH 27, 2024

New research shows that certain bacteria can alter antibodies so much that they’re unrecognizable to the body’s defenses — potentially leading to immune friendly fire. The bacteria, called Akkermansia muciniphila, can strip the sugar coating from IgA antibodies, immune proteins abundant in the gut.

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Immunity Immunization 350

STAT

JUNE 27, 2024

Supreme Court rejected a controversial bankruptcy deal in which the owners of Purdue Pharma sought to contribute up to $6 billion in exchange for immunity from further lawsuits. The immunity had been a huge sticking point and prevented the settlement, which was first approved by a bankruptcy judge three years ago, from being finalized.

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Immunity Immunization 363

STAT

AUGUST 21, 2023

The Food and Drug Administration on Monday approved a Pfizer vaccine that aims to protect newborns against RSV by vaccinating pregnant people in the latter part of pregnancy. The vaccine, Abrysvo, has also been approved for use in adults 60 and older to protect them against respiratory syncytial virus. Read the rest…

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Vaccines Immunity Immunization 246

STAT

FEBRUARY 20, 2025

It does so through your immune system, a vast army of cells that mobilizes to fight off Every time you get sick, your body keeps a record of it.

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Immunity Immunization 307

STAT

SEPTEMBER 27, 2024

Dupixent is already a blockbuster therapy for a range of immune-mediated diseases, but the Food and Drug Administration’s approval of the drug for chronic obstructive pulmonary disease greatly expands its reach — and could give it an edge over rival treatments in development. There are 300,000 such people in the U.S.,

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Immunity Immunization 319

STAT

APRIL 4, 2024

Many of the effects of climate change play out at a very large scale: Heatwaves that grip entire continents. Flooding that submerges vast swaths of island nations and continental coastal areas. Other effects are far less visible because they’re taking place inside people’s bodies. That doesn’t make them any less dangerous.

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Immunity Immunization 279

STAT

SEPTEMBER 8, 2024

The rationale for that urgency is this: An unexplained H5 infection raises the possibility of person-to-person spread of a flu virus that has never before circulated in humans, and to which people would not have immunity. And this with a dangerous flu virus that scientists have long feared could someday trigger a pandemic.

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Immunity Immunization 364

STAT

DECEMBER 7, 2022

When tumors like melanoma form, the immune system mobilizes for war. White blood cells called lymphocytes rush to assault the tumor — but cancer has ways of disabling the immune system. But those immune cells still have the potential to kill cancer cells. It’s called TIL, or tumor infiltrating lymphocyte therapy.

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Immunity Immunization 261

STAT

JUNE 14, 2024

This is precisely because vaccination requirements ensure that virtually every child’s immune system has been prepared to recognize and resist these diseases. Troubling stories about outbreaks of previously eradicated diseases like measles notwithstanding, most schools are free of vaccine-preventable diseases. Read the rest…

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Vaccines Immunity Immunization 347

STAT

MAY 13, 2024

They should also be paying attention to adults as a new, first-of-its-kind report quantifying the economic impact of adult immunizations makes clear. The number of children who received their routine vaccinations declined during the pandemic, so public health officials have been focusing on getting kids back up to date.

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Vaccines Immunity Immunization 362

STAT

JANUARY 30, 2023

However, federal officials watered down one of the auditing policies by giving insurers seven years of immunity from having the samples of their diagnosis coding errors extrapolated to their broader Medicare Advantage membership. Continue to STAT+ to read the full story…

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Immunity Immunization 363

STAT

FEBRUARY 15, 2024

It’s still not clear why so many positions were left unfilled on the Advisory Committee on Immunization Practices. STAT reported on the vacancies , which had flummoxed public health experts in the country, last week. Read the rest…

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Vaccines Immunity Immunization 354

STAT

MAY 5, 2023

Early hypotheses as to what was driving the heart inflammation, called myocarditis , included an allergic response to the vaccine, vaccine-induced antibodies, or an autoimmune response in which the immune system attacks the body’s own healthy tissue by mistake.

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Vaccines Immunity Immunization 364