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People in Republican-voting states more likely to report Covid-19 vaccine side effects, study says

STAT

People in Republican-voting states were more likely to report adverse events after receiving a Covid-19 vaccination than people living in Democratic-leaning states, a new analysis finds, suggesting that how people view their post-vaccine side effects or decide whether to report them may be shaped by their political views.

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Opinion: Better safety studies could restore America’s confidence in vaccines

STAT

In February 2021, I received my second Covid-19 shot — the newly developed vaccine that would eventually save millions of lives worldwide — with great anticipation. It was as if an audible dog whistle began blaring right next to me.

Vaccines 364
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STAT+: Novavax and Gavi end a bitter dispute over Covid-19 vaccines with a refund up to $400 million

STAT

After a contentious dispute, Novavax has agreed to refund up to $400 million to the international organization that purchased Covid-19 shots as part of a global vaccination program, but found itself with vaccines that were no longer needed. But as demand dried up last year, the vaccine makers kept $1.4

Vaccines 350
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STAT+: CRO claims there was no misconduct in Lyme vaccine trial it ran for Pfizer

STAT

A company that Pfizer blamed for problems with a clinical trial testing a Lyme vaccine claims that regulators gave its procedures a clean bill of health during a recent inspection. Care Access served as a contract research organization and had enrolled about 3,000 patients in the late-stage trial.

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STAT+: Pharmalittle: Novartis is losing its chief commercial officer; vaccine experts urge more inclusivity in clinical trials

STAT

In any event, there is work to be done, so as always, we have assembled a few items of interest for you. But the trials for the vaccines, which have been approved for adults 60 and older, included few participants 80 and older. But this is to be expected at this time of year, yes? Hope you have a successful day and conquer the world.

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STAT+: Pharmalittle: Pfizer scraps half of participants in Lyme vaccine trial over quality issues; Ginkgo CEO may have possible conflict of interest

STAT

who had been enrolled in a Phase 3 study testing a vaccine against Lyme disease due to violations of good clinical practice at certain trial sites run by a third party , STAT says. … Pfizer discontinued a significant percentage of participants in the U.S.

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SAEM Clinical Images Series: Post-Vaccination Rash

ALiEM - Pharm Pearls

A 42-year old Bengali man with a history of hyperlipidemia presented to the Emergency Department with facial swelling, diffuse rash, renal insufficiency and proteinuria after receiving his COVID-19 vaccine (Moderna) booster dose. Erythema multiforme has been reported as a cutaneous reaction after the COVID-19 mRNA vaccine.

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