Sat.Nov 30, 2024 - Fri.Dec 06, 2024

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The Role of Artificial Intelligence (AI) and Machine Learning (ML) in Drug Repurposing

Drug Patent Watch

In the ever-evolving landscape of pharmaceutical research and development, a revolutionary force is reshaping the way we approach drug discovery and repurposing. This force is none other than Artificial Intelligence (AI) and Machine Learning (ML).

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With Makary set to face FDA commissioner hearings, how deep do his industry ties run?

PharmaVoice

Dr. Marty Makary’s conflicts of interest could come into question before he is confirmed as the next FDA commissioner.

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‘Leptin’s last chance’: Mouse study says infamous weight loss drug failure could boost GLP-1s

STAT

The hormone leptin was discovered 30 years ago to much fanfare. Scientists hoped that leptin, which regulates body fat, could pave the way for obesity treatments. The results in mice were hailed as “miraculous,” and Amgen licensed the hormone for $20 million from Rockefeller University. But its initial promise failed to pan out, as treatments mimicking leptin in the body didn’t spur weight loss.

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Genmab expands its pipeline with $630m Scancell deal

pharmaphorum

Genmab has licensed another anti-glycan antibody for cancer from UK biotech Scancell as it continues to expand its in-house pipeline.

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From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

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EMCrit 389 – Massive Transfusion Update and Hemostatic Resuscitation

EMCrit Project

John Holcomb, author of the PROPPR trial, on massive transfusion in 2024 EMCrit Project by Scott Weingart, MD FCCM.

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Milk-based therapies could be coming. This biotech CEO is aiming to lead the way.

PharmaVoice

Intrinsic Medicines is entering phase 2 trials in Parkinson’s disease and IBS for its human milk oligosaccharide drug candidates next year.

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More Trending

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Race for approval of first oral GLP-1R drug in obesity intensifies with four in phase III trials: GlobalData

Express Pharma

In recent years, GLP-1 receptor (GLP-1R) products have gained immense popularity. Currently, four innovative GLP-1Rs are approved worldwide for obesity, all of which are injectables. This leaves a gap in the obesity market for an oral GLP-1R product. 63 drugs are in active development, with four Phase III products racing to earn the inaugural approval in this untapped market, says GlobalData.

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Lilly’s Zepbound beats Novo’s Wegovy in high-stakes obesity drug trial

BioPharma Dive

Results from the head-to-head study showed treatment with Zepbound resulted in 47% greater relative weight loss than Wegovy, a finding that could advantage Lilly in the companies’ market competition.

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The big rebrand: Why these 4 biopharmas changed their name this year

PharmaVoice

Four companies that refreshed their mission and public persona with a new look.

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Conservative-led Supreme Court appears wary of weighing in on trans care bans

STAT

Conservative Supreme Court justices appeared skeptical Wednesday of arguments that they should intervene in Tennessee’s ban on gender-affirming care for minors.  The court heard arguments in U.S. v. Skrmetti that the state’s ban discriminated against transgender minors and denied them constitutionally equal protections. Outside the courthouse, in a sonic representation of the cultural divisiveness around the issue, advocates for gender-affirming care access blasted Bad Bunny a

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Why Every Small Business Needs an HCM Solution: A Comprehensive Guide

Managing HR tasks like payroll, compliance, and employee data can overwhelm small businesses. That’s where a Human Capital Management (HCM) solution comes in. Our eBook, Why Every Small Business Needs an HCM Solution: A Comprehensive Guide , shows how an HCM system automates tedious processes, ensuring your business stays compliant and efficient. You’ll learn how to simplify payroll, eliminate costly errors, and empower your employees with self-service tools.

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Deadline looms for post-Brexit label changes for UK meds

pharmaphorum

The MHRA has reminded pharma companies that from 1st January all medicines sold in the UK will have to comply with new labelling requirements

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Antag Therapeutics secures €80 million in weight loss therapy financing

Pharma Times

Versant Ventures leads investment round to advance drug

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How Astellas juggles the moving parts of cancer precision medicine development

PharmaVoice

While developing its first-in-class gastric cancer drug Vyloy, Astellas had to coordinate with another pharma giant to usher the precision med into the market.

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STAT+: U.S. Patent Office pulls controversial rule to curb pharma patent abuse

STAT

In an unexpected move, the U.S. Patent & Trademark Office has withdrawn a controversial proposal that was designed to prevent pharmaceutical companies from abusing the patent system. Specifically, the proposed rule was crafted to stem the use of so-called patent thickets , which are wielded by drug companies to delay the arrival of lower-cost generic medicines in the marketplace.

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Best Practices to Streamline Compensation Management: A Foundation for Growth

Speaker: Joe Sharpe and James Carlson

Payroll optimization can be one of the most time-consuming and complex factors of small business management. Yet, organizations that crack the code on streamlining employee compensation often discover innovative avenues for growth. With the right strategies in place, outsourcing and streamlining payroll processes can result in substantial time and resource savings.

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'Concerning reports' of scam websites targeting weight loss and other shortage meds

The Pharmacist

Fake online pharmacies are targeting vulnerable patients whose medicines are in short supply, including obesity drugs, ADHD medication and hormone replacement therapy (HRT), the Royal Pharmaceutical Society (RPS) has reported. The Medicines and Healthcare products Regulatory Agency (MHRA) said such fraudulent supply was the work of 'organised criminal gangs', while the General Pharmaceutical (GPhC) warned […] The post 'Concerning reports' of scam websites targeting weight loss an

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How automating flow cytometry is revolutionising cancer diagnosis and treatment

pharmaphorum

Discover how the automation of flow cytometry is transforming cancer diagnosis and treatment for breast, prostate, endometrial, pancreatic, kidney, and melanoma cancers. Explore the latest advancements in the field.

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Can the girl power of Arrivo’s depression drug help reverse its fortunes?

PharmaVoice

After failing a mid-stage trial, the biotech shifted course and is now targeting females with the goal of proving gender can play a role in depression outcomes.

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Bird flu theories, the worst-rated restaurants, and not your grandfather’s radiation therapy

STAT

Get your daily dose of health and medicine every weekday with STAT’s free newsletter Morning Rounds.  Sign up here. Good morning! I hope you had a lovely holiday weekend and feel rested and ready for the last sprint of 2024.

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Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

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NICE endorses Neuraxpharm’s ublituximab for treating MS

Pharma Times

New antibody therapy shows promise in managing condition

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Diabetes advocacy group discourages use of compounded GLP-1 drugs

BioPharma Dive

The ADA recommended doctors avoid prescribing unapproved, off-brand versions of drugs like Wegovy, wading into a dispute that has gripped the FDA and compounding pharmacies over the past few months.

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GSK taps a startup for shot at Alzheimer’s drug

PharmaVoice

The collaboration deal, which could be worth hundreds of millions of dollars, is a “pivotal moment” for Muna Therapeutics, a startup that launched less than four years ago.

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STAT+: Why Orexo is abandoning a digital therapeutic for depression

STAT

Swedish pharmaceutical company Orexo will no longer pursue an app for treating depression after many years of struggling to sell it. Orexo announced this week that it will no longer license the product, called Deprexis, from German manufacturer GAIA. The companies have worked together on Deprexis in the United States since 2020 and have deals for two other apps, including Modia, an app that provides psychosocial support to people being treated for opioid addiction.

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Enhance Healthcare Efficiency With Top Payroll & HCM Services

Running a healthcare facility requires precision and care, not just for patients but also for your staff. Our guide, "A Buyer’s Guide to Payroll & HCM Services," helps healthcare providers choose the best provider. Efficient payroll management ensures timely, accurate payments, critical for maintaining staff morale and trust. Compliance support helps navigate complex healthcare regulations and avoid costly fines.

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SAEM Clinical Images Series: This Rash Came Out of No Where

ALiEM - Pharm Pearls

A 26-year-old male with a past medical history of eczema presented to the Emergency Department with a rash for two days. The patient stated he first noticed a rash on his right arm that rapidly spread to his face, chest, and left arm. He reported having similar rashes before but never to this extent. The patient stated he was given Bactrim and amoxicillin about one month ago for another rash, though he was unsure of the diagnosis.

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Pharma giants vie for oral GLP-1R approval

Pharma Times

Race to create first oral drug for obesity intensifies

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How Alexion markets a rare disease drug by ‘starting with the end in mind’

PharmaVoice

The biopharma, now an arm of AstraZeneca, needs to build the plane while flying it to be first in rare diseases with no other option.

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STAT+: Using AI to design small molecule drugs is tough. Here are five companies trying to crack the code

STAT

Ian Quigley was employee #13 at AI drug company Recursion until 2021, when he quit and turned the basement of his Utah home into a lab to develop AI models for predicting which proteins small molecule drugs might target — a tool he and co-founder Andrew Blevins found was missing during their time at Recursion.  When he was setting up the lab, Quigley ordered an Illumina DNA sequencer that the delivery person had wanted to leave on his porch.

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5 Reasons to Upgrade Your Pharmacy Management Software

Are you still using workarounds to manage your daily operations? To achieve peak performance, it's time to explore other options for specialty and infusion pharmacy software. Streamline pharmacy operations and improve clinical performance with automated processing, real-time data exchange, and electronic decision support. Download this helpful infographic to: Drive efficiency and patient adherence from referral receipt to delivery and ongoing care – all with our Pharmacy Cloud.

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Janux impresses Wall Street with new prostate cancer drug results

BioPharma Dive

While early and from a small trial, the findings suggest Janux’s method of “masking” T cell engagers could lead to differentiated results, some analysts said.

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Everest therapy shows promise in nephropathy trial

Pharma Times

Data highlights effectiveness of EVER001 in treating pMN

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Note from the Editor-in-Chief

PharmaVoice

A change in ownership and what it means for our readers.

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STAT+: Pharmalittle: We’re reading about U.K. restricting Lilly’s obesity drug, pharma layoffs, and more

STAT

Top of the morning to you, and a fine one it is, despite the dreary gray skies hovering over the Pharmalot campus. We are doing our best to maintain sunny spirits, though, because once again, we recall some helpful wisdom from the Morning Mayor, who taught us that “every new day should be unwrapped like a precious gift.” To celebrate the notion, we are brewing still more cups of stimulation and inviting you to join us.

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Incubators and innovation hubs: Accelerating entrepreneurship in life sciences

Express Pharma

“The first wealth is health,” said the American philosopher Ralph Waldo Emerson in 1860, and strides in life sciences entrepreneurship pronouncedly affect this form of wealth in any country. In India, the life sciences innovation, which includes pharma, biotech, and medtech, is valued at $30 billion in 2024. The country’s health metrics, such as the growing burden of non-communicable diseases, rising life expectancy, malnutrition, and air pollution, present a further scope for innovations