Sat.Aug 31, 2024 - Fri.Sep 06, 2024

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Missouri resident who had no contact with animals tests positive for bird flu

STAT

This is a developing story and will be updated. A person in Missouri who didn’t report any contact with animals has tested positive for H5 bird flu, the state’s Department of Health and Senior Services and the Centers for Disease Control and Prevention said Friday. It’s not yet clear if the person was infected with the same virus strain that’s causing the ongoing outbreak among dairy cattle.

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FDA adcomm reform talks heat up

PharmaVoice

As the agency considers eliminating adcomm votes from the approval process, members vie to have their voices heard.

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A decade of cancer immunotherapy: Keytruda, Opdivo and the drugs that changed oncology

BioPharma Dive

Over the past 10 years, PD1-blocking medicines have transformed cancer care. But the steady expansion of their use has slowed and, despite much trying, pharmaceutical companies have largely failed to top the drugs’ successes.

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The Life Sciences Generative AI Council and a sustainable technological future

pharmaphorum

Listen to the podcast interview with Manny Belabe from ArisGlobal as he discusses The Life Sciences Generative AI Council and its role in creating a sustainable technological future. Gain insights into the future of AI in life sciences.

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Why Every Small Business Needs an HCM Solution: A Comprehensive Guide

Managing HR tasks like payroll, compliance, and employee data can overwhelm small businesses. That’s where a Human Capital Management (HCM) solution comes in. Our eBook, Why Every Small Business Needs an HCM Solution: A Comprehensive Guide , shows how an HCM system automates tedious processes, ensuring your business stays compliant and efficient. You’ll learn how to simplify payroll, eliminate costly errors, and empower your employees with self-service tools.

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In a first, living mice are made transparent

STAT

When a dye called tartrazine is added to food, it creates a bright yellow hue often associated with lemon-flavored candy. But when mixed with a little water and daubed on the skin of mice, the dye makes their skin nearly transparent.  Researchers reported the new use for the common food dye today in the journal Science. The technique creates a fresh opportunity for researchers to understand what is going on under the skin of a live animal, which could eventually allow them to study the inne

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Pharma’s ‘it’ therapy — a new drug class gaining steam

PharmaVoice

More companies are investing in protein degraders, which leverage a unique approach to harnessing the immune system in cancer, neurological diseases and more.

More Trending

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China detains AstraZeneca workers in data, imports probe

pharmaphorum

A "small number" of AstraZeneca employees have been detained in China in an investigation into suspected data privacy and drug import breaches

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Trying to time your seasonal vaccines just right? There are no easy answers, but here are some factors to consider

STAT

With fall coming into view, public health officials across the country are turning to the annual task of persuading legions of Americans to get vaccinated against some combination of influenza, Covid-19, and respiratory syncytial virus, three bugs that sicken mass numbers of people over the winter months, often overwhelming hospitals and health care delivery in the process.

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What 3 layoff stories reveal about pharma’s troubles

PharmaVoice

The factors driving the industry’s layoffs — and what could help turn the tide.

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New research could ease concerns over suicide risk of obesity drugs

BioPharma Dive

While results from two after-the-fact analyses were “reassuring,” outside experts urged “continued vigilance” to ensure GLP-1 drugs don’t worsen problems in people with preexisting mental health conditions.

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From Payroll Pains to Growth Gains: Streamlining Payroll & HR for Success

Speaker: Joe Sharpe and James Carlson

In the world of small business management, the challenge of managing payroll & HR efficiently while scaling operations can be overwhelming. Yet, with the right strategies in place, these challenges can become opportunities for growth and innovation. In this session, Joe Sharpe, Senior Director of Managed Payroll Services at IRIS, will reveal practical methods and expert insights for outsourcing and streamlining payroll processes, resulting in substantial time and resource savings.

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GSK says Nucala hits the target in new COPD trial

pharmaphorum

GSK's severe asthma therapy Nucala could find a new lease of life as a treatment for chronic obstructive pulmonary disease (COPD) after showing a clear benefit in a phase 3 trial.

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Doctors use problematic race-based algorithms to guide care every day. Why are they so hard to change?

STAT

Pediatrician Alexandra Epee-Bounya had had enough. In her 20 years caring for children in Boston, she had seen hundreds of kids with suspected urinary tract infections. Each time, she’d turn to a calculator, used by all Boston Children’s Hospital clinicians, to judge the youngest childrens’ risk. Did the infant have a high fever?

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Pharmacy contract negotiations expected to resume 'soon'

The Pharmacist

Negotiations on the delayed community pharmacy contract in England are expected to resume 'soon', Community Pharmacy England (CPE) has said following a meeting with the pharmacy minister. CPE chief executive Janet Morrison, along with two community pharmacy members of the CPE negotiating team, has met with care minister Stephen Kinnock, the negotiator said.

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Immuneel Therapeutics welcomes Amit Mookim as CEO

Express Pharma

Immuneel Therapeutics a cell and gene therapy platform, announced the appointment of Amit Mookim as its new Chief Executive Officer. He brings over two decades of experience across life sciences, technology and private equity, making him ideally suited to lead Immuneel into its next phase of growth and innovation. Mookim joins Immuneel from IQVIA, a Fortune 500 in clinical research, technology and analytics, where he served as Managing Director for South Asia.

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Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

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Company Profile: Medscape WebMD

pharmaphorum

Medscape WebMD is a leading provider of medical information and services online, catering to the Medical Affairs field. Learn more about their company profile and offerings.

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Opinion: Letting funding for the All of Us research program lapse will cost the U.S. far more than it saves

STAT

I was in high school when I first encountered the ruthlessness of the number one killer in the U.S. A close friend of mine, then only 16 years old, witnessed his father having a heart attack while checking the mail. Despite desperate attempts at CPR on the driveway, he wasn’t able to save his dad, a seemingly healthy man in his early 40s. That event put me on a path to become a cardiologist.

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NPA warns of 'pharmacy deserts' in rural and deprived areas

The Pharmacist

Disproportionately low pharmacy provision and over-reliance on one pharmacy group could put rural areas at risk of becoming a 'pharmacy desert', the National Pharmacy Association (NPA) has warned. And above-average levels of closures in deprived areas risk widening health inequalities, the association added. In new analysis published today, the NPA found that 87% of local […] The post NPA warns of 'pharmacy deserts' in rural and deprived areas appeared first on The Pharmacist.

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Moderna’s updated Covid-19 vaccine receives positive EMA CHMP opinion

Pharmaceutical Business Review

This recommendation will aid in the potential authorisation of the vaccine for use in individuals aged six months and older to prevent Covid-19 in the upcoming 2024-2025 autumn/winter season. The CHMP’s positive opinion is grounded in a comprehensive evaluation, including manufacturing and preclinical data, as well as earlier clinical, non-clinical, and real-world evidence confirming the vaccine’s efficacy and safety.

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Enhance Healthcare Efficiency With Top Payroll & HCM Services

Running a healthcare facility requires precision and care, not just for patients but also for your staff. Our guide, "A Buyer’s Guide to Payroll & HCM Services," helps healthcare providers choose the best provider. Efficient payroll management ensures timely, accurate payments, critical for maintaining staff morale and trust. Compliance support helps navigate complex healthcare regulations and avoid costly fines.

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Lykos CEO steps down after MDMA is rejected by FDA

pharmaphorum

The fallout from the FDA's recent decision not to approve Lykos Therapeutics' psychedelic treatment has spread to its senior management, with chief executive Amy Emerson stepping down.

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STAT+: Diagnosed with cancer, a pharmaceutical executive became a patient advocate and changed drug development. It took decades

STAT

Kathy Giusti was diagnosed with multiple myeloma in 1996, when she was a 37-year-old executive at the drug company G.D. Searle. She was told she had three years to live. Twenty-eight years later, Giusti, 65, is thriving. One reason is the patient advocacy group she founded in 1998: the Multiple Myeloma Research Foundation. The group has raised more than $600 million for research, launched nearly 100 clinical trials, and helped bring more than 15 new drugs to market.

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HDA 2024 Traceability Seminar: Best Practices Amid the Forthcoming Stabilization Period

Pharmaceutical Commerce

In the second part of her interview with Pharma Commerce Editor Nicholas Saraceno, Ilisa B.G. Bernstein, President of Bernstein Rx Solutions, LLC, discusses the best practices that compliance teams should consider as the end of the stabilization period approaches this November.

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The Role of Green Chemistry in Generic Drug Development: A Sustainable Approach to Medicine

Drug Patent Watch

The pharmaceutical industry is a significant contributor to global carbon emissions, with a projected increase of over 300% by 2050 if left unchecked. This alarming trend has led to a growing need for sustainable practices in the industry, particularly in the development of generic drugs.

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5 Reasons to Upgrade Your Pharmacy Management Software

Are you still using workarounds to manage your daily operations? To achieve peak performance, it's time to explore other options for specialty and infusion pharmacy software. Streamline pharmacy operations and improve clinical performance with automated processing, real-time data exchange, and electronic decision support. Download this helpful infographic to: Drive efficiency and patient adherence from referral receipt to delivery and ongoing care – all with our Pharmacy Cloud.

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Alnylam hails vutrisiran data, but investors seem sceptical

pharmaphorum

Alnylam Pharma has been riding high since revealing top-line results from its HELIOS-B trial of vutrisiran in transthyretin-mediated amyloidosis (ATTR) – but a look at the full data seems to have disappointed investors.Shares in the company retreated after the presentation of the results at the European Society of Cardiology (ESC) conference, which confirmed a 28% reduction in the primary endpoint of deaths from any cause and recurrent cardiovascular events after at least 33 months of follow-up.

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Moderna reports encouraging results on its mpox vaccine, as outbreaks in Africa spread

STAT

The emergence of a second mpox outbreak in which the virus is spreading from person-to-person, as well as a sharp increase in overall cases of the disease in several African countries, is straining the world’s capacity to make and distribute vaccine to battle the threat. New options are needed, and a study published Wednesday suggests another may be on the horizon.

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High-dose psilocybin may be effective in treating depression

The Pharmacist

High doses of psilocybin – the psychedelic ingredient in magic mushrooms – appear to have a similar effect on depressive symptoms as an antidepressant, according to a meta-analysis of the evidence. But some of the promise of psychedelic treatment for depression may have been overestimated due to issues with trial design, the results suggest. The […] The post High-dose psilocybin may be effective in treating depression appeared first on The Pharmacist.

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HDA 2024 Traceability Seminar: Legal Advice for DSCSA Compliance Teams

Pharmaceutical Commerce

In an interview with Pharma Commerce Editor Nicholas Saraceno, Ilisa B.G. Bernstein, President of Bernstein Rx Solutions, LLC, highlights the hard-hitting points that she anticipated will be covered during her session at the 2024 HDA Traceability Seminar.

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Roche trumpets new fenebrutinib data in relapsing MS

pharmaphorum

Data from a phase 2 trial of Roche's oral BTK inhibitor fenebrutinib have shown "near-complete suppression" of disease activity and disability progression in relapsing multiple sclerosis (MS).The full results of the FENopta open-label extension study are due to be reported in full at the ECTRIMS congress in Copenhagen later this month, but top-line findings include that 99% of patients treated with fenebrutinib were free of T1 gadolinium-enhancing lesions, markers of active inflammation, at 48 w

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Upending a longstanding paradigm, cardiologists embrace ZIP codes, not race, to predict heart risk

STAT

N ot only is Joseph Wright a physician, he’s the chief health equity officer for the American Academy of Pediatrics. So he was skeptical when, at his annual checkup in January, an alert popped up on his doctor’s computer screen. A calculator embedded in Wright’s health record had automatically pulled in his data, including the blood test he had done that morning.

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Primary care staff need more support to manage rise in food allergies, say researchers

The Pharmacist

Primary care staff need urgent support and training to care for people with food allergies, according to researchers who found that numbers have doubled since 2008. An analysis published in The Lancet Public Health said the largest rise had been seen in young children but the reasons behind the trend were not clear. In a study of […] The post Primary care staff need more support to manage rise in food allergies, say researchers appeared first on The Pharmacist.

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FDA grants ODD to Abdera’s neuroendocrine carcinoma treatment

Pharmaceutical Technology

The US FDA has granted orphan drug designation (ODD) to Abdera Therapeutics’ ABD-147 aimed at neuroendocrine carcinoma.

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Illumina avoids hefty EU fine over Grail merger

pharmaphorum

EU had no grounds to probe Illumina's takeover of Grail, says ECJ, but while spinoff has already taken place Illumina can now avoid a €432m fine

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STAT+: Vor Biopharma’s ‘shielded’ transplant delays relapse in leukemia patients

STAT

A CRISPR-augmented stem cell transplant that protects healthy cells from the toxic effects of anti-cancer medicines has shown preliminary evidence that it can delay relapse in patients with an aggressive form of leukemia, its maker Vor Biopharma said Thursday.  In the early stage study, eight of 10 patients with high-risk acute myeloid leukemia remain in remission after receiving a transplant with the Vor therapy, called trem-cel, followed by maintenance treatment with intensified doses of

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