Sat.Oct 26, 2024 - Fri.Nov 01, 2024

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Top 10 CDMO Services You Didn’t Know You Needed

Drug Patent Watch

The pharmaceutical industry relies heavily on Contract Development and Manufacturing Organizations (CDMOs) to streamline the drug development and manufacturing process. CDMOs provide a wide range of services that cater to the diverse needs of pharmaceutical companies, from early-stage development to commercial manufacturing.

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STAT+: These 10 scientists are leading a new generation of gene editors developing CRISPR medicines

STAT

Barely 12 years after the publication of the first papers unveiling CRISPR-Cas9, a powerful enzyme for editing DNA, sickle cell patients are now receiving the first approved CRISPR-based medicine, Casgevy. Hundreds of patients with other inherited diseases, cancers, and chronic bacterial and viral infections are enrolled in clinical trials testing other CRISPR treatments.

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Trending Sources

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On the front lines of the superbug war, new treatments can’t arrive soon enough

PharmaVoice

As antimicrobial resistance rises, researchers are running out of time to fight each new wave of superbugs. And the funding isn’t enough.

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SAEM Clinical Images Series: Clot in Transit

ALiEM - Pharm Pearls

A 67-year-old male with a past medical history of CHF, MI, hypertension, and diabetes presented to the ED with complaints of headache, chest pain, and dyspnea for the past four days. He stated that he has been without his medications for the past few months due to cost. He denied any past surgical history. He stated that he primarily presented because he felt like “my blood pressure is high” Additional Images Physical Exam Cardiovascular : Tachycardic, 2+ pedal edema bilaterally Re

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From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

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Community Pharmacies in Crisis: Navigating the Challenges and Closures

Pharmaceutical Commerce

With today's pharmacy landscape shaken by unprecedented and wider disruption to healthcare support and delivery, community and independent entities strive to remain an integral cog in the mix.

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Limiting sugar in infancy is tied to less diabetes and hypertension in adulthood

STAT

Britain’s hardships during World War II famously included weeks of bombing during the Blitz, the mass evacuation of children, and food rationing. That rationing, researchers report, holds cautionary lessons for today on the health impact of consuming sugar early in life.  Black-and-white wartime photos capture long queues in the shops when supplies of meat, dairy, sugar, and other food were limited.

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SAEM Clinical Images Series: Wilma, Take a Look at This!

ALiEM - Pharm Pearls

A 2-year, 11-month-old female with a history of constipation was brought to the ED by her mother for abdominal pain. The mother noticed that the patient’s abdomen had been enlarging for months. When they visited the pediatrician several months ago, the pediatrician also noticed a mildly enlarged abdomen but the patient was asymptomatic at that time.

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Novo, with new results, to seek approval for obesity drug in MASH

BioPharma Dive

The Phase 3 findings position semaglutide to become the first drug of its kind for the liver disease. But they also confirm GLP-1s aren't a "silver bullet" for MASH, one analyst argued.

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Bird flu found in a pig in U.S. for the first time, raising concerns about potential risks to humans

STAT

H5N1 bird flu virus has been found in a pig on a farm in Oregon, the first time the virus has been seen in a pig in the United States, the U.S. Department of Agriculture reported Wednesday. The pig, one of five on the farm, did not display signs of illness. Two others tested negative and testing is ongoing on the other two. All five were euthanized to allow for study of whether the animals were truly infected.

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Where Big Pharma’s campaign cash is flowing in this election

PharmaVoice

Big Pharma CEOs are hedging all bets by supporting both sides of the aisle in the 2024 election.

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Why Every Small Business Needs an HCM Solution: A Comprehensive Guide

Managing HR tasks like payroll, compliance, and employee data can overwhelm small businesses. That’s where a Human Capital Management (HCM) solution comes in. Our eBook, Why Every Small Business Needs an HCM Solution: A Comprehensive Guide , shows how an HCM system automates tedious processes, ensuring your business stays compliant and efficient. You’ll learn how to simplify payroll, eliminate costly errors, and empower your employees with self-service tools.

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Tranq dope (fentanyl-xylazine combination): A new horizon in opioid withdrawal treatment

ALiEM - Pharm Pearls

‘Dope’ is no longer heroin in an increasing number of our communities. The biggest change has been the gradual replacement of diacetylmorphine (heroin) by fentanyl and other synthetic opioids. Due in large part to the proliferation of anonymous chemical factories able to produce industrial volumes of inexpensive synthetic opioids without opium or other controlled precursors, fentanyl spilled into the United States, Canada, and Europe, heroin soon fell to market forces [1, 2].

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NICE trumpets new standard for health AI evaluations

pharmaphorum

With artificial intelligence technologies for healthcare on the rise, UK health technology assessment (HTA) agency NICE has published an economic evaluation standard that it says will help inform coverage and reimbursement decisions.

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Lawsuit to fix pulse oximeter bias makes progress with device manufacturers

STAT

In 2022, Noha Aboelata noticed something troubling. The founding CEO of a health clinic that serves a predominantly Black and brown population, she realized that the racial biases built in pulse oximeters were hurting her patients in Oakland, California. The devices overestimate blood oxygen in people with darker skin tones, making them appear healthier than they are.

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Backlash builds against Novo’s Catalent takeover

PharmaVoice

Roche recently joined naysayers who argue the deal threatens competition in the burgeoning weight loss and diabetes drug market.

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Best Practices to Streamline Compensation Management: A Foundation for Growth

Speaker: Joe Sharpe and James Carlson

Payroll optimization can be one of the most time-consuming and complex factors of small business management. Yet, organizations that crack the code on streamlining employee compensation often discover innovative avenues for growth. With the right strategies in place, outsourcing and streamlining payroll processes can result in substantial time and resource savings.

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Informal referrals deprive pharmacies of 'more than £115m a year'

The Pharmacist

Informal referrals to community pharmacies deprive pharmacies of more than £115 million each year, Community Pharmacy England (CPE) has estimated. This is the amount that would have been paid if existing referral routes had been used appropriately by GPs and NHS 111, rather than patients being signposted informally to their local community pharmacy.

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Biogen refreshes its C-suite; Novartis writes down MorphoSys assets

BioPharma Dive

Daniel Quirk, an immunology and neuroscience executive at Bristol Myers Squibb, will be Biogen’s next chief medical officer, while Robin Kramer will replace retiring CFO Michael McDonnell.

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STAT+: Dreams of cancer vaccines are becoming more real. Here are 9 scientists making it happen 

STAT

Vaccines are the original immunotherapy, in the view of Ryan Sullivan, a cancer immunotherapy researcher and oncologist at Mass General Cancer Center. But many other modes of immunotherapy for cancer were approved first — checkpoint blockade drugs like Keytruda and engineered immune cell therapies like Yescarta. Shadowed by the successes of other therapies, the field of cancer vaccines was “seemingly dying,” Sullivan said.

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Big Pharma earnings hang hope on the next generation of blockbusters

PharmaVoice

Pfizer, J&J, Biogen and Novartis are banking on new products to make up for maturing blockbusters, but future growth is not guaranteed.

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Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

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Lilly touts new Kisunla regimen that reduces side effects

pharmaphorum

Eli Lilly says a new starting dose regimen for its Alzheimer's disease therapy Kisunla reduces the risk of side effects that have stood in the way of approvals and reimbursement decisions for drugs in its class.Simply shifting one vial of the anti-amyloid antibody from the first infusion to the third infusion of the titration phase of dosing – the period used to achieve therapeutic levels in the body – is enough to lower the incidence of a potentially serious side effect known as ARIA-E, accordi

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What does this week's Budget mean for pharmacists in general practice?

The Pharmacist

In the Autumn Budget this week, chancellor Rachel Reeves committed to providing an additional £22.6bn to the ‘day-to-day health budget’ – including £100m to use on upgrades to 200 general practice estates in England. The budget also outlined minimum wage increases which may have a knock-on impact across the board, but are currently unfunded in […] The post What does this week's Budget mean for pharmacists in general practice?

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U.S. death from Lassa fever, an Ebola-like virus, is reported in Iowa 

STAT

A person from Iowa who recently returned to the United States from West Africa has died after contracting Lassa fever, a virus that can cause Ebola-like illness in some patients. State health officials reported the case on Monday. “I want to assure Iowans that the risk of transmission is incredibly low in our state. We continue to investigate and monitor this situation and are implementing the necessary public health protocols,” Robert Kruse, state medical director of the Iowa Depa

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Novo takes big step toward ending Ozempic, Wegovy shortages

BioPharma Dive

All doses of the two drugs are now listed as available in the U.S., per an FDA database, although the company cautioned patients may still experience "variability" filling their prescriptions.

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Enhance Healthcare Efficiency With Top Payroll & HCM Services

Running a healthcare facility requires precision and care, not just for patients but also for your staff. Our guide, "A Buyer’s Guide to Payroll & HCM Services," helps healthcare providers choose the best provider. Efficient payroll management ensures timely, accurate payments, critical for maintaining staff morale and trust. Compliance support helps navigate complex healthcare regulations and avoid costly fines.

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Novartis gets FDA okay for frontline use of Scemblix in CML

pharmaphorum

Novartis says FDA approval for frontline use of its leukaemia drug Scemblix will boost the number of eligible patients four-fold, as it hunts blockbuster sales

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See how your pharmacy compares as July Pharmacy First data released

The Pharmacist

July 2024 saw the highest number of pharmacies meeting the Pharmacy First monthly threshold since it increased to 10 consultations in May, according to the latest Pharmacy First data. Nationally, clinical pathway consultations and urgent medicine supply referrals increased overall. But minor illness referrals decreased in July 2024. Scroll down for our interactive Pharmacy First […] The post See how your pharmacy compares as July Pharmacy First data released appeared first on The Pharmacis

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Tracking the U.S. bird flu outbreak has been hard. It’s about to get harder

STAT

If one can point to anything good about the H5N1 bird flu outbreak in dairy cattle — to be honest, there’s nothing good about this situation — it’s the timing. Transmission of the virus through U.S. dairy herds took off when last winter’s flu season was effectively over, making the job of looking for people infected with H5N1 an easier task in theory, though there have been plenty of human hurdles impeding those efforts.

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The quest for quality continues

Express Pharma

Quality was once again in the spotlight at two recent industry meets. While regulators kept their sights on raising the compliance bar, industry chiefs pledged adherence to these codes. Not surprisingly, most speakers focused on the importance of trust. At the Indian Pharmaceutical Alliance’s (IPA) virtual 9th Advanced Good Manufacturing Practices (GMP) Workshop Dr Rajeev Raghuvanshi, Drugs Controller General of India, CDSCO, Government of India commented, “At the heart of the pharmaceutic

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5 Reasons to Upgrade Your Pharmacy Management Software

Are you still using workarounds to manage your daily operations? To achieve peak performance, it's time to explore other options for specialty and infusion pharmacy software. Streamline pharmacy operations and improve clinical performance with automated processing, real-time data exchange, and electronic decision support. Download this helpful infographic to: Drive efficiency and patient adherence from referral receipt to delivery and ongoing care – all with our Pharmacy Cloud.

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Why language training is crucial for healthcare teams

pharmaphorum

Effective language training for healthcare teams within the NHS is crucial for providing quality care and communication with diverse patient populations. Learn why it is essential for healthcare professionals.

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Verastem Oncology submits NDA for ovarian cancer treatment

Pharmaceutical Technology

Verastem Oncology has concluded the rolling submission of a new drug application (NDA) to the US Food and Drug Administration (FDA) for a combination of avutometinib and defactinib for low-grade serous ovarian cancer (LGSOC).

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National Academies calls to change how biomedical research uses race and ethnicity

STAT

Race and ethnicity are applied in inappropriate and even harmful ways in biomedical research, the National Academies of Science, Engineering, and Medicine said in a report issued Wednesday , calling on scientists, research funders, and publishers to transform the way they use — and don’t use — the categories in research. “The current use of race and ethnicity in research is sometimes seen as an exercise in checking boxes or a matter of using the ‘right’

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A new biotech, built around protein design, springs from David Baker’s lab

BioPharma Dive

Archon Biosciences, co-founded by the winner of the 2024 Nobel Prize in Chemistry, emerged from stealth Wednesday with $20 million in seed capital.

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Teva fined €462.6m for antitrust delay to MS drug rivals

pharmaphorum

The European Commission has delivered a hefty fine to Teva for abusing a dominant position in multiple sclerosis by artificially extending the patent protection for former blockbuster Copaxone.

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