Sat.Feb 11, 2023 - Fri.Feb 17, 2023

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Current treatments for cramps aren’t cutting it. Why aren’t there better options?

STAT

One day last fall, Kiran’s period cramps became so painful they woke her up from a nap. The 19-year-old took some ibuprofen, but found little relief. “The pain was so bad, it felt like someone was punching me,” said Kiran, who asked to be referred to by only her first name for privacy. It felt “like I was giving birth.

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Brian Fox is bringing ‘fresh eyes’ to ad agency Klick

PharmaVoice

Why the recently appointed president of commercial solutions sees near limitless potential to expand Klick’s footprint across the life sciences — and how generative AI is playing a role.

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ACMT Toxicology Visual Pearl: Swollen Lips

ALiEM - Pharm Pearls

Photo used with permission The following physical finding would be most consistent with exposure to which of the following? Bee sting Household bleach Isopropyl alcohol Potassium hydroxide Reveal the Answer Answer 4 – Potassium hydroxide Background The markedly swollen lips and drooling in this photo are seen following a caustic ingestion. Potassium hydroxide, also known as potash, is a caustic substance found in fertilizers, cleaning supplies, and some hair products.

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Virtual reality training in pharma: just a headset away?

European Pharmaceutical Review

The COVID-19 pandemic led to an unparalleled paradigm shift in the use of and the incorporation of new technologies into our workflows. This was particularly apparent in academia and the pharmaceutical industry, where we have seen words such as Teams and Zoom becoming part of our new lexicon of language for meetings. Now we reach for these types of online meetings without a second thought, due to the clear productivity benefits they provide over real in-person meetings. 1 However, notwithstandin

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From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

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Opinion: The haunting brain science of long Covid

STAT

Matt Fitzgerald used to bike up and down 3,500 feet through the Santa Ana Mountains on three-hour rides just for fun. Now, nine months after being infected with SARS-CoV-2, the virus that causes Covid-19, he can’t muster walking on flat surfaces for 20 minutes without days of exhaustion. “My long Covid life remains terrifying,” he told me.

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Pheast’s new CEO on how its ‘don’t eat me’ platform could deliver next-gen precision immunotherapies

PharmaVoice

Jacopo Leonardi’s latest venture is in the burgeoning field of macrophage inhibitors that could target a wide range of cancers.

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More Trending

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Weight loss jabs to be sold via high street chemists in England

The Guardian - Pharmaceutical Industry

Appetite suppressant Wegovy, popular with celebrities, seen as breakthrough treatment but not permanent remedy Weekly weight-loss jabs that are popular with celebrities will soon be made available through high street chemists in England, despite controversy over their use. Many people struggle to tackle obesity through diet and exercise alone as they often find they regain the weight that they lose.

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STAT+: In about-face, Moderna vows Americans won’t have to pay for its Covid-19 vaccine

STAT

In an unexpected shift, Moderna has decided not to ask Americans to pay for its Covid-19 vaccine, a move that follows intense criticism over initial plans to charge $110 to $130 per dose after the company pivots from government contracts to commercial distribution. The vaccine maker released a brief statement that it “remains committed” to ensuring everyone in the U.S. has access to its Covid-19 shot, regardless of whether they have health insurance coverage.

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Managing for resilience: Passage’s ups and downs in gene therapy

PharmaVoice

After a rocky year, Passage Bio’s CEO is focused on helping the rare disease specialist bounce back.

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Sun Pharma recalls at least 34,000 bottles of generic drug

Pharmafile

Mumbai-based pharma company, Sun Pharma, has announced that it is recalling over 34,000 bottles of a generic drug, Diltiazem Hydrochloride, from the US market. The drug is used for treating high blood pressure, angina and some types of irregular heartbeat. This recall follows the FDA’s Enforcement Report, which saw “failed impurity (Deacetyl Diltiazem Hydrochloride) specification during stability testing and failed dissolution testing at FDA laboratory.

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Why Every Small Business Needs an HCM Solution: A Comprehensive Guide

Managing HR tasks like payroll, compliance, and employee data can overwhelm small businesses. That’s where a Human Capital Management (HCM) solution comes in. Our eBook, Why Every Small Business Needs an HCM Solution: A Comprehensive Guide , shows how an HCM system automates tedious processes, ensuring your business stays compliant and efficient. You’ll learn how to simplify payroll, eliminate costly errors, and empower your employees with self-service tools.

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European Commission awards €7.7 million to mechanochemistry project

European Pharmaceutical Review

The European Commission (EC) has awarded IMPACTIVE almost €7.7 million to study the possibilities of mechanochemistry in the synthesis of active pharmaceutical ingredients (APIs). The ‘green’ project is a collaboration led by the University of Montpellier, in France. It is anticipated to reinvent and reinforce the pharmaceutical supply chain. The mechanochemistry initiative is funded by Horizon Europe and works with 17 partners in academia and industry working together towards greener chemistry.

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STAT+: CRISPR pioneer Feng Zhang launches new genetic delivery startup with $193 million

STAT

Akin Akinc was scouring his email spam box last summer, looking for a missing message, when he stumbled across an unexpected email from a quite recognizable name: Feng Zhang. Zhang, one of the leading scientists in the groundbreaking field of genetic editing, had reached out two days prior to discuss a new company he was working on. Since helping to discover CRISPR-Cas9 — often referred to as molecular scissors that can cut into the genome and edit DNA — Zhang has founded at least

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Survey results: Social influences HCP perceptions and prescriptions

PharmaVoice

Build social strategies into marketing plans to reach HCPs with sharply focused messaging.

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How epilepsy researchers are moving the needle past anti-seizure treatments

Pharmaceutical Technology

While several therapeutics are available for treating symptoms associated with epilepsy, researchers and patients have strongly called out the need for more holistic treatments that would address the condition as a whole. Although recently approved drugs can treat seizures more safely, they do not treat the comorbidities that patients experience. Several biotech companies and researchers are now exploring medical devices and gene therapies to address not just common forms of epilepsy, but also r

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Best Practices to Streamline Compensation Management: A Foundation for Growth

Speaker: Joe Sharpe and James Carlson

Payroll optimization can be one of the most time-consuming and complex factors of small business management. Yet, organizations that crack the code on streamlining employee compensation often discover innovative avenues for growth. With the right strategies in place, outsourcing and streamlining payroll processes can result in substantial time and resource savings.

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Analytical platform could advance mRNA medicine QC

European Pharmaceutical Review

Tokyo researchers have developed a new analytical platform based on liquid chromatography, mass spectrometry and software analysis that quantifies the structure of messenger RNA (mRNA)-based medicines. The method is an important innovation for quality control ( QC) in production lines. The platform can elucidate mRNA sequences while quantifying ‘capping’ at one end of the molecule and the integrity of the tail on the other, all vital in mRNA pharmaceuticals.

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A rare Marburg outbreak sparks a race against time to test vaccines and drugs

STAT

A Marburg fever outbreak in Equatorial Guinea is galvanizing efforts to test drugs and vaccines for a virus that currently has none. But every day counts, warned experts who gathered virtually on Tuesday to try to chart a course for the work. The outbreak is believed to have begun in early January, but the confirmation that the Marburg virus was responsible for the growing cluster of people sick with hemorrhagic-fever-like illness was only confirmed on Monday.

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The post-COVID outlook for decentralized clinical trials

PharmaVoice

The COVID-19 pandemic had many pharmas turning to DCTs as a way to keep the clinical wheel turning. Can the industry keep that flexibility going forward?

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Leading innovators in kidney disorder treatment compositions for the pharmaceutical industry

Pharmaceutical Technology

The pharmaceutical industry continues to be a hotbed of innovation, with activity driven by the evolution of new treatment paradigms, and the gravity of unmet needs, as well as the growing importance of technologies such as pharmacogenomics, digital therapeutics, and artificial intelligence. In the last three years alone, there have been over 633,000 patents filed and granted in the pharmaceutical industry, according to GlobalData’s report on Innovation in Pharmaceuticals: Kidney disorder treatm

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Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

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Pfizer and BioNTech mRNA shingles vaccine study begins

European Pharmaceutical Review

Pfizer Inc. and BioNTech SE have announced the start of a Phase I/II trial for the companies’ mRNA vaccines for shingles (Herpes Zoster), for which there is no currently approved vaccine. Without vaccination, about half of the people who live to age 85 are expected to develop shingles, stated BioNTech. Both the incidence and severity of shingles rise with age, the company acknowledged.

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STAT+: FDA approves first treatment for leading cause of blindness in older people

STAT

The Food and Drug Administration approved on Friday the first treatment for geographic atrophy, a progressive eye disease and a leading cause of blindness in older people. The new drug, called Syfovre, is made by Apellis Pharmaceuticals.

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Woman of the Week: Bristol Myers Squibb’s Ester Banque

PharmaVoice

The 30-year veteran is heading up the “transformation” of one of the Big Pharma’s most important therapeutic portfolios: hematology.

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Innovation in immuno-oncology: Leading companies in cancer monoclonal antibody therapy

Pharmaceutical Technology

The pharmaceutical industry continues to be a hotbed of innovation, with activity driven by the evolution of new treatment paradigms and the gravity of unmet need, as well as the growing importance of technologies such as pharmacogenomics, digital therapeutics, and artificial intelligence. In the last three years alone, there have been over 633,000 patents filed and granted in the pharmaceutical industry, according to GlobalData’s report on Immuno-oncology: Leading companies in cancer monoclonal

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Enhance Healthcare Efficiency With Top Payroll & HCM Services

Running a healthcare facility requires precision and care, not just for patients but also for your staff. Our guide, "A Buyer’s Guide to Payroll & HCM Services," helps healthcare providers choose the best provider. Efficient payroll management ensures timely, accurate payments, critical for maintaining staff morale and trust. Compliance support helps navigate complex healthcare regulations and avoid costly fines.

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Key developments: mRNA vaccines and therapeutics

European Pharmaceutical Review

Recently there have been several key advances in the clinical development of messenger RNA (mRNA) vaccines, including vaccines for RSV and a personalised cancer vaccine. Since the COVID-19 pandemic, the industry has seen a spike in interest in mRNA therapeutics, due to the success of mRNA vaccines treating the virus, observed GlobalData. Initially developed to treat viral infections, mRNA vaccines deliver a piece of genetic material that instructs the body to make a protein fragment of a target

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Opinion: Improving patient safety shouldn’t be a financial calculation

STAT

A recent study of medical error published in The New England Journal of Medicine reached a shocking conclusion about patient safety: Nearly a quarter century after a highly publicized Institute of Medicine report on the prevalence of patient harm sparked vows to cut the rate by half in five years , “in-hospital adverse events” remain so common that they affect roughly one in four patients.

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Nectin’s Keytruda combo could fill gaps in immuno-oncology’s treatment paradigm

PharmaVoice

The Israeli biotech just entered into a collaboration with Merck to develop its own checkpoint inhibitor alongside the bestselling cancer treatment.

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Pfizer update Lyme disease vaccine candidate

Pharma Times

Research concerning candidate VLA15 has been discontinued across certain trial sites

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5 Reasons to Upgrade Your Pharmacy Management Software

Are you still using workarounds to manage your daily operations? To achieve peak performance, it's time to explore other options for specialty and infusion pharmacy software. Streamline pharmacy operations and improve clinical performance with automated processing, real-time data exchange, and electronic decision support. Download this helpful infographic to: Drive efficiency and patient adherence from referral receipt to delivery and ongoing care – all with our Pharmacy Cloud.

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Enzyme replacement therapy for alpha-mannosidosis gets FDA approval

European Pharmaceutical Review

The US Food and Drug Administration (FDA) has approved Lamzede ® (velmanase alfa-tycv) for non-central nervous system manifestations of alpha-mannosidosis (AM) in adult and paediatric patients. AM is an ultra-rare, progressive lysosomal storage disorder caused by deficiency in the enzyme α-mannosidase. Giacomo Chiesi, Head of Chiesi Global Rare Diseases stated that symptoms of the disorder include “impaired hearing, speech and mobility that progress from childhood into adulthood.

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Survey: Nearly 3 in 5 teen girls felt persistently sad or hopeless in 2021

STAT

Teen girls reported record levels of violence, sadness, and thoughts of suicide in 2021, experiencing distress at twice the rate of teen boys, according to new federal data released Monday. The nearly 3 in 5 teen girls who felt persistently sad or hopeless in 2021 was a 60% increase compared to a decade earlier.

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For Complement’s CEO, storytelling could be just as critical as data

PharmaVoice

Dr. Rafiq Hasan has his sights on bringing lessons learned at Bayer to ophthalmology-focused Complement Therapeutics.

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NAC for Thyroid Antibody Reduction, Detoxification and Gut Health

The Thyroid Pharmacist

A few years ago, I was asked: “If the supplement police came to your house and said you had to give up all but one of your supplements, which supplement would you keep, and why?” My answer: N-Acetyl Cysteine (also known as NAC for short), because it has numerous benefits on multiple body systems! Research has shown that NAC helps to reduce thyroid antibodies.

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I. AM. THE. DOCTOR. – Story From The Front Lines

Med Ed 101

This article was originally written by Christine Meyer, MD and I found this story too good not to share. I’m appreciative to her for letting me share it. Deprescribing and dose reductions require all hands on deck. Kudos to all of you pharmacists out there doing your best to ensure patients are taking necessary medication […] The post I.

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