Sat.Jun 29, 2024 - Fri.Jul 05, 2024

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‘Visionary’ study finds inflammation, evidence of Covid virus years after infection

STAT

Remember when we thought Covid was a two-week illness? So does Michael Peluso, assistant professor of medicine at the University of California, San Francisco.  He recalls the rush to study acute Covid infection, and the crush of resulting papers. But Peluso, an HIV researcher, knew what his team excelled at: following people over the long term.

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In the rapidly shrinking COVID market, this company still sees opportunity

PharmaVoice

GeoVax is developing a next-gen COVID vaccine targeting a population that’s so far been elusive: immunocompromised patients.

Vaccines 245
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10 clinical trials to watch in the second half of 2024

BioPharma Dive

Study results are expected for a pair of closely watched obesity drugs, while key tests await for a high-priced AbbVie acquisition and one of 2023’s largest IPOs.

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Changing Faces: Digital and supplier hires from April 2024

pharmaphorum

Changing Faces explores the digital and supplier hires from April 2024, with a focus on companies like SPT Labtech, Sphere Fluidics, Newel Health, and Diaceutics. Stay updated on the latest developments in the industry.

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Why Every Small Business Needs an HCM Solution: A Comprehensive Guide

Managing HR tasks like payroll, compliance, and employee data can overwhelm small businesses. That’s where a Human Capital Management (HCM) solution comes in. Our eBook, Why Every Small Business Needs an HCM Solution: A Comprehensive Guide , shows how an HCM system automates tedious processes, ensuring your business stays compliant and efficient. You’ll learn how to simplify payroll, eliminate costly errors, and empower your employees with self-service tools.

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Study links Ozempic to higher risk of eye condition that can cause vision loss

STAT

A new observational study on Wednesday reported for the first time a potential link between Novo Nordisk’s GLP-1 drugs Ozempic and Wegovy and an eye condition that can cause vision loss. After hearing anecdotes of patients on the diabetes and obesity drugs experiencing nonarteritic anterior ischemic optic neuropathy, or NAION, researchers at Massachusetts Eye and Ear analyzed data from a registry of patients at their institution to see if there was a broad trend.

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‘Accidental’ media switch leads to CAR T therapy discovery

European Pharmaceutical Review

Altering the conditions that T cells are grown in can improve CAR T-cell therapy, US researchers have found. Discovered by chance, their new method has potential to treat solid cancer tumours more efficiently, according to the findings. Putting T cells on a keto diet [putting our T cells on a three-day ‘keto’ diet] showed reduced maturity at the end of the manufacturing process.

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ASCO 2024: Emphasising the art and science behind enhanced cancer care

pharmaphorum

ASCO 2024 conference highlights the latest advancements in oncology, emphasising the art and science behind enhanced cancer care. Stay updated on the latest research, treatments, and innovations in the field of oncology.

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CDC looks to expand capacity to test for H5N1 bird flu in people

STAT

As the H5N1 bird flu outbreak in dairy cows enters its fourth month, the Centers for Disease Control and Prevention is taking steps to ramp up the nation’s capacity to test for the virus in people. In a call with reporters Tuesday, Nirav Shah, the CDC’s principal deputy director, emphasized that the risk to the general public remains low at this time.

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UK’s antibiotic subscription funding model – a route to market sustainability?

Pharmaceutical Technology

On 8 May, the UK was the world's first government to formally implement a new model for the funding and support of novel antibiotic commercialisation.

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Lilly drug for Alzheimer’s approved by FDA

BioPharma Dive

The drug, which Lilly will sell as Kinsunla, carries a warning for the risk of a certain kind of imaging abnormality that can be serious in rare cases.

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Best Practices to Streamline Compensation Management: A Foundation for Growth

Speaker: Joe Sharpe and James Carlson

Payroll optimization can be one of the most time-consuming and complex factors of small business management. Yet, organizations that crack the code on streamlining employee compensation often discover innovative avenues for growth. With the right strategies in place, outsourcing and streamlining payroll processes can result in substantial time and resource savings.

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The power and potential of regenerative medicine

pharmaphorum

The field of muscle stem cell research has been tangibly developing over the decades and in today’s pharmaphorum podcast wed editor Nicole Raleigh speaks with Dr Michael Rudnicki, co-founder and CSO of Satellos Biosciences, a company dedicated to developing novel therapeutics based on this science for those who live with Duchenne muscular dystrophy (DMD) and other degenerative muscle diseases.

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As bird flu spreads among U.S. cattle, veterinarians find themselves in a familiar position: the frontlines

STAT

When, in April, the federal government began requiring some cows to be tested for a strain of avian flu before their herds could be moved across state lines, it seemed like an obvious step to try to track and slow the virus that had started spreading among U.S. dairy cattle. But Joe Armstrong, a veterinarian at the University of Minnesota extension school, feared the U.S.

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Community pharmacy contract will be ‘one of new government’s first tasks’

The Pharmacist

Negotiating the new community pharmacy contract will be one of the first tasks of the new Labour government, Community Pharmacy England (CPE) has said. But even in a 'best-case scenario', negotiations might not begin for several weeks, CPE suggested. Commenting on the Labour Party’s win this morning, CPE chief executive Janet Morrison said that concluding […] The post Community pharmacy contract will be ‘one of new government’s first tasks’ appeared first on The Pharmacist.

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5 FDA decisions to watch in the third quarter

BioPharma Dive

Multibillion-dollar buyouts from Bristol Myers Squibb and Gilead could yield new drugs for brain and liver diseases, while a new cell therapy may reach market.

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Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

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Frontiers Health 2024: The foundational pillars

pharmaphorum

Frontiers Health, a prominent event in health innovation, has unveiled the foundational pillars that will define its legacy and future trajectory. The announcement of these pillars precedes their global conference, scheduled for the 17th and 18th of October in Berlin.

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STAT+: GLP-1s lower risk of 10 obesity-associated cancers, study shows

STAT

New research finds that the GLP-1 class of drugs — glucagon-like peptide receptor agonists — is more effective in mitigating the risk of 10 obesity-associated cancers than its type 2 diabetes drug alternatives. The retrospective study, published Friday in JAMA Network Open , measured results for a cohort of more than 1.6 million patients with type 2 diabetes from 2005 to 2018 who were prescribed GLP-1s, insulin, or metformin.

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Esteve invests €100 million in Spanish API manufacturing muscle

Outsourcing Pharma

The Spanish company Esteve Pharmaceuticals is building a manufacturing unit in its Girona plant with the aim to expand its production of active pharmaceutical ingredients (APIs).

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Eisai and Bristol Myers cancel cancer ADC deal

BioPharma Dive

The Japan-based drugmaker said its U.S. partner’s “portfolio prioritization efforts” led to the termination. It will refund part of an upfront payment.

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Enhance Healthcare Efficiency With Top Payroll & HCM Services

Running a healthcare facility requires precision and care, not just for patients but also for your staff. Our guide, "A Buyer’s Guide to Payroll & HCM Services," helps healthcare providers choose the best provider. Efficient payroll management ensures timely, accurate payments, critical for maintaining staff morale and trust. Compliance support helps navigate complex healthcare regulations and avoid costly fines.

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Innovation in generics: Increased efficiency through peptide API synthesis expertise

pharmaphorum

Discover how innovative approaches and specialised expertise in peptide API synthesis are increasing efficiency and driving advancements in the manufacturing of Active Pharmaceutical Ingredients (API).

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Bird flu snapshot: A pathologist sees familiar echoes in U.S. response to the outbreak

STAT

Bird flu snapshot: This is the latest installment in a series of regular updates on H5N1 avian flu that STAT is publishing on Monday mornings. To read future updates you can also subscribe to STAT’s Morning Rounds newsletter. When pathologist Thijs Kuiken looks at what’s happening in the U.S. response to the H5N1 bird flu outbreak in dairy cows, he’s reminded of a difficult period in the Netherlands, where he lives, back in the late aughts.

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Discover Vitamin B12 Types | An Essential Nutrient For Health

Welltopia Pharmacy

Vitamin B12 types are crucial for understanding how this nutrient impacts our health and how to choose the best form for supplementation. Vitamin B12, also known as cobalamin, is a crucial water-soluble vitamin that plays a vital role in various bodily functions. It is essential for DNA synthesis, red blood cell formation, and neurological function.

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Constipation Polypharmacy

Med Ed 101

JE is a 77-year-old male. He reports significant constipation despite the use of three laxative medications. In this case summary, I will outline the most important medications that can contribute to constipation polypharmacy. Past medical history includes: The current constipation medications he is taking include: Other medications include: Constipation Polypharmacy Review The first thing I […] The post Constipation Polypharmacy appeared first on Med Ed 101.

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5 Reasons to Upgrade Your Pharmacy Management Software

Are you still using workarounds to manage your daily operations? To achieve peak performance, it's time to explore other options for specialty and infusion pharmacy software. Streamline pharmacy operations and improve clinical performance with automated processing, real-time data exchange, and electronic decision support. Download this helpful infographic to: Drive efficiency and patient adherence from referral receipt to delivery and ongoing care – all with our Pharmacy Cloud.

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AstraZeneca files rival to Pemgarda for COVID PrEP

pharmaphorum

AstraZeneca may have exited the COVID-19 vaccine market, but it is still hoping to protect vulnerable patients with its antibody sipavibart for pre-exposure prophylaxis (PrEP).The drugmaker said this morning that an application for sipavibart (AZD3152) has been accepted for review by the EMA as PrEP for immunocompromised patients who often do not respond adequately to vaccination alone and remain at high risk of serious outcomes from COVID-19.

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STAT+: Ascension is racing to unload hospitals as execs work to stem losses

STAT

For 15 years, a formidable CEO-CFO duo often called “the two Tonys” ushered their St. Louis-based health system through a period of explosive growth, adding hospital after hospital until it became one of the country’s biggest health systems. The year after former CEO Anthony Tersigni and former finance chief Anthony Speranzo stepped down, their sprawling empire of roughly 140 hospitals underwent the ultimate stress test: the Covid-19 pandemic.

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CHMP meeting highlights – June 2024

European Pharmaceutical Review

At its recent June meeting, the EMA’s human medicines committee (CHMP) recommended 10 medicines for approval. Recommendations for regulatory approval The committee saw a need to give a marketing authorisation to Balversa (erdafitinib) as a treatment for adults with unresectable or metastatic urothelial carcinoma. In its meeting, the CHMP gave a positive opinion for the first nasally administered emergency treatment for allergic reactions.

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NeuroSense Therapeutics shares positive results of lead candidate in ALS

Pharma Times

The neurodegenerative disease currently affects more than 200,000 people worldwide

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Is the UK’s healthcare spending drop sustainable?

pharmaphorum

Explore the reasons behind the drop in the UK's healthcare spending and analyse whether this trend is sustainable for the NHS in the long term. Learn about the potential impacts and future implications.

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Opinion: Senate, FTC cracking down on pharma patent shenanigans

STAT

Why do Americans pay so much more for common medications than people in other countries? Why does an inhaler that costs $7 in France cost almost $500 in the United States? These are just a few of the questions the Senate Judiciary Committee looked to answer in a recent hearing. The common answer? Dominant corporations use a variety of patent-related strategies to protect their power, maximize their profits, and squash their competition.

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NSAID Problems – Polypharmacy Case Study

Med Ed 101

With this med review, I’m simply looking at a medication list to help formulate ideas to investigate. I’ll focus heavily on my concern for using an NSAID in this patient. NSAID and Heart Failure Concerns There are a few issues of note with the cardiac/heart failure medication regimen. I always have the prescribing cascade in […] The post NSAID Problems – Polypharmacy Case Study appeared first on Med Ed 101.

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Researchers find whole genome sequencing improves care for paediatric cancer

Pharma Times

Affecting around 3,755 young people in the UK every year, leukaemia is the most commonly diagnosed cancer in children

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Changing Faces: Pharma and biotech hires from April 2024

pharmaphorum

Explore the latest hires in pharma and biotech, including executive moves at Seaport Therapeutics, Anthos Therapeutics, Pfizer, and Novartis, from April 2024. Stay updated with the industry's top talent movements.

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STAT+: FDA approves Eli Lilly’s early Alzheimer’s treatment

STAT

Eli Lilly’s early Alzheimer’s treatment was approved by the Food and Drug Administration on Tuesday, making it the second drug on the U.S. market aimed at slowing progression of the debilitating neurological disease. The treatment, whose scientific name is donanemab and will be sold under the brand name Kisunla, will compete with Eisai and Biogen’s Leqembi, which got full approval last year.

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