Sat.Jun 15, 2024 - Fri.Jun 21, 2024

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STAT+: Vertex reports positive results in stem cell trial for type 1 diabetes

STAT

ORLANDO — Twelve people with type 1 diabetes who received a therapy derived from stem cells were able to produce enough of their own insulin to maintain healthy blood glucose levels 90 days later, Vertex Pharmaceuticals said Friday. All but one reduced or eliminated the need to inject insulin over those three months and three people followed for one year no longer needed to inject insulin at all.

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Avoiding the pharma ‘junk pile’ with launch readiness, pipeline rigor and ‘quick kills’

PharmaVoice

Drug launches have underperformed expectations at a high rate, and pharmas need to get better at thinning the pipeline to make room for the real wins, says a life sciences consultant.

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New data showcase promise, growing pains of CAR-T in autoimmune disease

BioPharma Dive

One expert described trial results presented at EULAR last week as “unprecedented.” But reports of relapses in some patients drew questions about the therapies’ ultimate potential.

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Pharmacists with a disability: Standing Up for Sitting Down campaign

The Pharmacist

When pharmacists with a disability told the Pharmacists’ Defence Association (PDA) they were having problems with suitable adjustments in their workplace, a campaign was launched to raise awareness of what employers need to consider. Liz Larkin reviews the issues. When members of the PDA’s Ability Network named their campaign against disability discrimination, ‘Standing Up for […] The post Pharmacists with a disability: Standing Up for Sitting Down campaign appeared first on The Pharmacist

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From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

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STAT+: Gilead’s twice-yearly antiviral protected women from HIV infection in large trial

STAT

Gilead said Thursday that twice-a-year injections of a new antiviral drug, called lenacapavir, completely protected cisgender women from contracting HIV in a large Phase 3 trial. In the study, none of the 2,134 women who received lenacapavir contracted HIV. By comparison, 16 of the 1,068 women who received the long-running daily pill Truvada contracted HIV.

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New data showcase promise, growing pains of CAR-T in autoimmune disease

PharmaVoice

One expert described trial results presented at EULAR last week as “unprecedented.” But reports of relapses in some patients drew questions about the therapies’ ultimate potential.

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Novavax seeks FDA approval for updated Covid-19 vaccine

Pharmaceutical Technology

Novavax has sought US FDA approval for an updated JN.1 version of its Covid-19 vaccine, NVX-CoV2705, for individuals aged 12 years and above.

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Opinion: Long Covid feels like a gun to my head

STAT

I have spent my career studying infectious diseases that fall under the heading of neglected tropical diseases. Now I have a neglected disease — long Covid — an incurable (for now and for me) disease. As a medical anthropologist working in global health, I thought I understood the despair of poor health. I didn’t. I join 7% of the U.S. adult population — or about 18 million Americans — who have experienced long Covid.

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NIH-funded trials fall flat on diversity goals

PharmaVoice

Many clinical trials aren’t meeting enrollment inclusion checkpoints — and some aren’t even setting targets, according to a recent OIG report.

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Two-thirds of pharmacies slash opening hours amid funding pressures

The Pharmacist

Almost two-thirds of pharmacies in England have decreased their opening hours since 2015, latest analysis from the National Pharmacy Association (NPA) has suggested. The research, based on a sample of 110 pharmacies, found that on average there has been a 6.1-hour (10%) reduction in opening hours for every pharmacy. The findings come as up to […] The post Two-thirds of pharmacies slash opening hours amid funding pressures appeared first on The Pharmacist.

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Why Every Small Business Needs an HCM Solution: A Comprehensive Guide

Managing HR tasks like payroll, compliance, and employee data can overwhelm small businesses. That’s where a Human Capital Management (HCM) solution comes in. Our eBook, Why Every Small Business Needs an HCM Solution: A Comprehensive Guide , shows how an HCM system automates tedious processes, ensuring your business stays compliant and efficient. You’ll learn how to simplify payroll, eliminate costly errors, and empower your employees with self-service tools.

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PulmCrit: Bilevel Sequence Intubation (BSI) – The new standard

EMCrit Project

introduction Bilevel Sequence Intubation (BSI) refers to initiation of noninvasive bilevel positive pressure ventilation with a backup rate prior to intubation (either using a BiPAP machine or a full-featured mechanical ventilator). BSI is distinct from traditional rapid sequence intubation (RSI), since BSI involves the delivery of machine-initiated, pressure-controlled breaths following administration of sedation and paralytics. […] EMCrit Project by Josh Farkas.

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New Merck pneumococcal vaccine wins FDA approval

STAT

The Food and Drug Administration on Monday approved Merck’s new pneumococcal vaccine for adults 18 and older. The vaccine, which will be sold under the name Capvaxive, is designed to protect against pneumococcal pneumonia, which hospitalizes about 150,000 adults in the United States every year and kills about 1 in 20 who develop it, according to the National Foundation for Infectious Diseases.

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Blood test could spot Parkinson’s years earlier

pharmaphorum

An AI-powered blood test that may be able to predict Parkinson’s years before symptoms develop could allow earlier treatment and guide trials of new treatments

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Paul Rees: 'We need to keep the pressure up'

The Pharmacist

The Pharmacist caught up with National Pharmacy Association (NPA) chief executive Paul Rees during today's ‘day of action’ to save community pharmacies, at a branch of Green Light Pharmacy in central London. Paul, tell us how the Save Our Pharmacies day of action campaign has been going today? For the first time ever, community pharmacies […] The post Paul Rees: 'We need to keep the pressure up' appeared first on The Pharmacist.

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Best Practices to Streamline Compensation Management: A Foundation for Growth

Speaker: Joe Sharpe and James Carlson

Payroll optimization can be one of the most time-consuming and complex factors of small business management. Yet, organizations that crack the code on streamlining employee compensation often discover innovative avenues for growth. With the right strategies in place, outsourcing and streamlining payroll processes can result in substantial time and resource savings.

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Adam Fabriwerk inaugurates its New Testing Facility in Ambad, Nashik

Express Pharma

Headquartered in Kandivali, Mumbai, Adam Fabriwerk inaugurated its new dedicated testing facility at Plot No. D-57, Ambad, MIDC on June 20 2024. The state-of-the-art facility specialises in Factory Acceptance Testing (FAT), capable of integrating and testing vessels up to 250,000 litres. Established in 1982, Adam Fabriwerk specialised in customised process system solutions for Pharmaceutical and Bio-pharmaceutical industries.

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Opinion: With the threat of H5N1 bird flu, hospitals must stay prepared

STAT

A third case of mammal-to-human transmission of the highly pathogenic H5N1 bird flu virus has been reported in the United States. This latest case, involving a dairy worker in Michigan , raises concerns due to the individual exhibiting respiratory symptoms, highlighting the pandemic potential of this virus. U.S. hospitals need to prepare for the worst and hope for the best.

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12 Questions with Caroline Phillips

pharmaphorum

Dive into an exclusive Medscape interview with HCP Caroline Phillips as she shares her insights, experiences, and advice. Discover the key takeaways that can benefit your medical practice.

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First patient dosed in Assembly Biosciences’ phase 1b trial for hepatitis B treatment

Pharmafile

Assembly Biosciences has announced that the first participant has been dosed in its phase 1b trial of ABI-4334, the company’s next-generation capsid assembly modulator (CAM) candidate currently being developed for the treatment of chronic hepatitis B virus (HBV) infection. The post First patient dosed in Assembly Biosciences’ phase 1b trial for hepatitis B treatment appeared first on Pharmafile.

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Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

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Life sciences industry forecasts significant revenue from connected health within 5 years

Express Pharma

A substantial 63 per cent of life sciences companies, including those in biopharma, currently have connected health products on the market or in development. Regardless of their product development stage, these organisations predict that connected health will generate over 20 per cent of their revenue within five years. Yet a lack of essential data capabilities could hamper this ambition.

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Inside Anthony Fauci’s ‘On Call’: 9 health and science takeaways from the memoir of America’s most famous doctor

STAT

Anthony Fauci spent 40 years in the top echelons of government. It was no accident. To read the forthcoming memoir by the country’s former top infectious disease expert, “On Call: A Doctor’s Journey in Public Service,” a copy of which was obtained by STAT, is to get a sense of his finesse while advising seven presidents. He strove, he writes, to speak with complete candor and stay out of politics, while remaining strategic in pushing for policies he considered vital t

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Neuroplastogens: A novel approach to treat neurological diseases

pharmaphorum

Learn about the innovative approach of using neuroplastogens, including psychedelics, to treat neurological diseases. Explore the potential benefits and risks of this novel treatment method.

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Public support 'Save Our Pharmacies' petition with over 100k signatures

The Pharmacist

A cross-sector petition to ‘save’ community pharmacies reached over 100,000 signatures even before yesterday’s ‘day of action’, during which even more members of the public were invited to sign. The National Pharmacy Association (NPA) reported ‘hundreds of signatures being collected at pharmacies across the four nations each day’, which, when combined with signatures collected online, […] The post Public support 'Save Our Pharmacies' petition with over 100k signatures appeared fi

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Enhance Healthcare Efficiency With Top Payroll & HCM Services

Running a healthcare facility requires precision and care, not just for patients but also for your staff. Our guide, "A Buyer’s Guide to Payroll & HCM Services," helps healthcare providers choose the best provider. Efficient payroll management ensures timely, accurate payments, critical for maintaining staff morale and trust. Compliance support helps navigate complex healthcare regulations and avoid costly fines.

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Syngene announces 2nd year of STEM scholarship and mentorship program for women in collaboration with RICH

Express Pharma

Syngene International, an integrated research, development and manufacturing services company, announced the second cohort of the scholarship, mentoring and industry orientation for women in STEM (science, technology, engineering, and mathematics) in collaboration with the Research and Innovation Circle of Hyderabad (RICH). This program offers scholarships to women studying STEM subjects at tier two and three institutions across various regions of the country to enable them to gain industry exp

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Vaping is just as good as Chantix at helping people quit cigarettes, new study finds

STAT

WASHINGTON — E-cigarettes were about as effective at helping people quit smoking as the gold-standard pharmaceutical drug, varenicline, according to a clinical trial published Monday in JAMA Internal Medicine. The trial randomized 458 people who smoked daily and wanted to quit to receive either a nicotine-containing e-cigarette and placebo tablets, varenicline and an e-cigarette without nicotine, or a placebo tablet and a nicotine-free e-cigarette for 12 weeks.

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How data is critical to commercialising drugs for rare diseases

pharmaphorum

Discover the importance of data in the process of commercialising drugs for rare diseases and how it plays a critical role in advancing treatment options for patients. Learn more about orphan diseases and drug development.

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FDA lifts hold on PTC Huntington’s disease trial

BioPharma Dive

The agency has lifted a partial trial suspension based on one-year data showing PTC’s pill suppressed a key protein associated with the disorder.

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5 Reasons to Upgrade Your Pharmacy Management Software

Are you still using workarounds to manage your daily operations? To achieve peak performance, it's time to explore other options for specialty and infusion pharmacy software. Streamline pharmacy operations and improve clinical performance with automated processing, real-time data exchange, and electronic decision support. Download this helpful infographic to: Drive efficiency and patient adherence from referral receipt to delivery and ongoing care – all with our Pharmacy Cloud.

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CALQUENCE plus chemoimmunotherapy reduced the risk of disease progression or death by 27% vs. standard of care in patients with untreated mantle cell lymphoma in ECHO Phase III trial

Express Pharma

The recent results from the ECHO Phase III trial showed AstraZeneca’s CALQUENCE (acalabrutinib) in combination with bendamustine and rituximab demonstrated an improvement in progression-free survival (PFS) and showed a favourable trend in overall survival (OS) compared to standard-of-care chemoimmunotherapy (bendamustine plus rituximab) in previously untreated patients with mantle cell lymphoma (MCL).

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Bird flu snapshot: A critic of the U.S. response speaks out, and USDA tries to ‘corner the virus’

STAT

Bird flu snapshot: This is the first in a series of regular updates on H5N1 avian flu that STAT is publishing on Monday mornings. To read future updates you can also subscribe to STAT’s Morning Rounds newsletter. Seth Berkley, the former head of Gavi, the Vaccine Alliance, gave voice last week to a point of view STAT has been hearing for a while about the U.S. response to the H5N1 bird flu outbreak in dairy cows.

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The next frontier: How to use AI-powered analytics for life sciences marketing

pharmaphorum

Discover how AI-powered analytics are revolutionising life sciences marketing. Learn how to leverage these cutting-edge technologies to drive insights and success in the industry.

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Obesity drug from Zealand shows potential in early trial

BioPharma Dive

Interim study data suggest the Danish drugmaker can remain in the race to develop new kinds of weight loss drugs as doctors seek alternatives to the now dominant GLP-1s.

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Powering India’s pharmacuetical innovation: The need for an industry-academia collaboration

Express Pharma

India, synonymous with the “pharmacy of the world” has rightfully earned the title, owing to its remarkable contribution in supplying 20 per cent of the global generic medicines, along with 60 per cent of the total vaccine demand worldwide. From the Covid-19 pandemic to the floods in Sri Lanka in 2017, India has made significant contributions in assisting several nations, irrespective of geographies – especially in terms of providing low-cost vaccines and other medical aid.

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