STAT

FEBRUARY 21, 2023

A bedrock of the U.S. mental health system — a nine-item questionnaire used to spot depression — began not with a doctor, but with a marketing man. Howard Kroplick, now 73 years old and living on Long Island, is obsessed with antique racing cars and, in his storied career in the pharmaceutical industry, crucially urged Pfizer to avoid the word “impotence” when promoting Viagra.

340

340

PharmaVoice

FEBRUARY 21, 2023

The rare disease market is set for major growth in the decade to come, and pharma companies are securing their footholds now.

245

245

ALiEM - Pharm Pearls

FEBRUARY 24, 2023

What is the proposed mechanism for the pictured antidote when used as a pressor for refractory vasoplegic shock? Alpha-1-adrenergic agonist Angiotensin II receptor antagonist Nitric oxide/cyclic GMP pathway inhibition Vasopressin-1 receptor agonist Reveal the Answer Answer 3 – Inhibition along the nitric oxide (NO)/cyclic GMP pathway Background Vasoplegic shock is a maldistribution of blood flow and inadequate oxygen delivery secondary to an abnormally low systemic vascular resistance [1].

Labelling 173

Labelling 173

European Pharmaceutical Review

FEBRUARY 21, 2023

The UK medicinal cannabis sector has witnessed important regulatory advances in recent years. After the substance became legal in the UK in 2018, pharmaceutical companies have faced numerous obstacles to attain a fairer position in the industry. Crucially, January 2023 marked a key moment: the Medicines and Healthcare products Regulatory Agency (MHRA) granted Celadon Pharmaceuticals the first good manufacturing practice (GMP) registration since legalisation in 2018 for high Δ9-tetrahydrocannabin

Pharmaceutical Companies 132

Pharmaceutical Companies Pharmaceutical Companies Compounding Drug Development 132

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

Communication

STAT

FEBRUARY 24, 2023

A classic warning in public health goes like this: “A society that spends so much on health care that it cannot or will not spend adequately on other health enhancing activities may actually be reducing the health of its population.” No nation is as guilty of this practice as the United States, with its extremely high health expenditures alongside abysmal population-level health outcomes.

292

292

PharmaVoice

FEBRUARY 22, 2023

Kristen Fortney, CEO of BioAge Labs, wants to improve the human life span by focusing on the human health span.

246

246

European Pharmaceutical Review

FEBRUARY 24, 2023

University Hospital Erlangen in Germany is the first in the world to use chimeric antigen receptor (CAR) T-cells to successfully treat a patient suffering from a severe case of muscle inflammation (myositis). The researchers noted that risk of developing a very severe form of the autoimmune inflammatory disease is high. The patient who received the CAR T treatment was diagnosed with anti-synthetase syndrome.

Immunization 128

Immunization Immunity Hospitals 128

STAT

FEBRUARY 24, 2023

Ever since fentanyl entered the U.S. drug supply, many Americans seeking treatment for opioid addiction have found that only a single medication is effective at easing cravings and withdrawal: methadone. But even though the drug is widely considered to be safe and effective, there’s not much data about how methadone stacks up against its main alternative, buprenorphine.

274

274

PharmaVoice

FEBRUARY 23, 2023

Despite a court ruling, the FDA is sticking to its narrow orphan drug exclusivity approach. But confusion remains over the policy’s future.

130

130

PhRMA

FEBRUARY 23, 2023

State legislative sessions across the country are in full swing, and many state officials have made lowering the cost of medicine for patients a top priority. If policymakers are serious about addressing high out-of-pocket costs for patients, they should start by taking steps to finally hold pharmacy benefit managers (PBMs) accountable.

110

110

Advertisement

Managing HR tasks like payroll, compliance, and employee data can overwhelm small businesses. That’s where a Human Capital Management (HCM) solution comes in. Our eBook, Why Every Small Business Needs an HCM Solution: A Comprehensive Guide , shows how an HCM system automates tedious processes, ensuring your business stays compliant and efficient. You’ll learn how to simplify payroll, eliminate costly errors, and empower your employees with self-service tools.

European Pharmaceutical Review

FEBRUARY 23, 2023

Advances with microbiological methods are providing more accurate and sensitive datasets at a faster rate, relating to bacterial identity, numbers, responses to environments and so on. Recent years have seen progress with applying a long-established spectrophotometric phenomenon – Raman spectra – to advance our understanding of bacterial populations, including differentiating between living and dead cells and interpreting phenotypic variations to different environmental stressors.

Labelling 121

Labelling Packaging Drug Development 121

STAT

FEBRUARY 19, 2023

Watching news reports of the heroic relief efforts underway in Turkey and Syria following the devastating earthquake there, I can imagine the terrible weight of emotional trauma that so many people are experiencing right now because I’ve experienced it myself. A dozen years ago, as a young doctor with a background in emergency medicine, I felt prepared to handle disaster response situations.

261

261

PharmaVoice

FEBRUARY 21, 2023

A slew of early stage biotechs were forced to shut down last year as the market tanked. Will the trend continue?

148

148

Pharma Times

FEBRUARY 21, 2023

Final draft guidance from NICE ensures people at highest risk will have access to COVID-19 therapies

143

143

Speaker: Joe Sharpe and James Carlson

Payroll optimization can be one of the most time-consuming and complex factors of small business management. Yet, organizations that crack the code on streamlining employee compensation often discover innovative avenues for growth. With the right strategies in place, outsourcing and streamlining payroll processes can result in substantial time and resource savings.

European Pharmaceutical Review

FEBRUARY 21, 2023

Included in this issue of European Pharmaceutical Review : FOREWORD Accelerating drug development David Elder, David P Elder Consultancy RAMAN SPECTROSCOPY Shining a light on Raman for microbiological analysis Tim Sandle, Bio Products Laboratory LIMS Overcoming barriers to capturing data in a laboratory Samantha Kanza, University of Southampton ENVIRONMENTAL MONITORING Endotoxin trends: sustainability, automation and beyond Miriam Guest, AstraZeneca UK REGULATORY INSIGHT UPC opt-out – a strateg

Drug Development 111

Drug Development 111

STAT

FEBRUARY 21, 2023

This year could shape up to be a historic one for tobacco control — or one in which Big Tobacco accelerates its steady transformation into Big Nicotine. We are hoping for the former, but aren’t betting against the latter. For the last few years, the tobacco industry has publicly endorsed harm reduction. This public health strategy includes efforts designed to reduce, though not eliminate, risks for people who engage in harmful behaviors.

261

261

PharmaVoice

FEBRUARY 24, 2023

With a scientific platform based on muscle biology, the late-stage biotech is addressing cardiovascular and neuromuscular diseases.

130

130

Pharma Times

FEBRUARY 23, 2023

Next phase of Newel Health’s digital therapeutics solution for Parkinson’s disease gains vital grant

132

132

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

European Pharmaceutical Review

FEBRUARY 23, 2023

Pharmaceutical microbiologists are subordinate to the firms they are employed by, so usually a firm’s challenges – and how they choose to address them – will dictate the challenges of its employees. Although there is some overlap between the challenges relevant to firms and to their microbiologists, there is some attendant level of misalignment that does need frank recognition, robust discussion and which necessarily demands reconciliation.

Dosage 111

Dosage Vaccines 111

STAT

FEBRUARY 23, 2023

The shouting began soon after my son was born. “We’ve got an inversion!” the doctor yelled to his team. Moments earlier, a nurse had pressed my newborn son against my chest. I bent to kiss his dark curls through my surgical mask, then he and my husband were escorted out of the operating room.

254

254

PharmaVoice

FEBRUARY 22, 2023

The first-time CEO has her sights on addressing thousands of diseases with the company’s tRNA platform.

130

130

Pharmaceutical Technology

FEBRUARY 22, 2023

Amgen could be the winner of a high-stakes patent spat with Sanofi as tensions run high weeks before the March 27 US Supreme Court hearing. While some courts were previously on Sanofi’s side, it is possible that Amgen’s case could win this time, some legal experts say. However, Sanofi’s side also has significant support, highlighting the dispute’s contentious nature.

104

104

Advertisement

Running a healthcare facility requires precision and care, not just for patients but also for your staff. Our guide, "A Buyer’s Guide to Payroll & HCM Services," helps healthcare providers choose the best provider. Efficient payroll management ensures timely, accurate payments, critical for maintaining staff morale and trust. Compliance support helps navigate complex healthcare regulations and avoid costly fines.

European Pharmaceutical Review

FEBRUARY 24, 2023

The Committee for Medicinal Products for Human Use (CHMP) has issued a positive opinion recommending approval of ruxolitinib cream (Opzelura ) for non-segmental vitiligo with facial involvement in people over 12 years old. “With no centrally approved treatment option currently available in the EU, this positive opinion marks a significant milestone for the vitiligo community,” explained Dr Steven Stein, Chief Medical Officer, Chief Medical Officer, Incyte.

105

105

STAT

FEBRUARY 20, 2023

Heather Rendulic yearns to use both hands to fill up her plate at a hotel buffet, or slice up her own steak. She wants to pull her hair into a ponytail. She’s tried to teach her husband, but it always comes out a bit messy. Almost nine years after a stroke paralyzed the left side of her body at age 23, Rendulic sat in a lab at the University of Pittsburgh and used her left hand to cut a steak.

246

246

PharmaVoice

FEBRUARY 23, 2023

The VP of public affairs at Kyowa Kirin discusses her role in advocating for advocacy.

130

130

Pharma Times

FEBRUARY 22, 2023

Research will analyse how Huawei’s wearable technology detects atrial fibrillation in post-stroke patients

124

124

Advertisement

Are you still using workarounds to manage your daily operations? To achieve peak performance, it's time to explore other options for specialty and infusion pharmacy software. Streamline pharmacy operations and improve clinical performance with automated processing, real-time data exchange, and electronic decision support. Download this helpful infographic to: Drive efficiency and patient adherence from referral receipt to delivery and ongoing care – all with our Pharmacy Cloud.

Pharmacy Management

European Pharmaceutical Review

FEBRUARY 23, 2023

Two newer simplified treatment options are at least as effective as standard of care in achieving viral suppression, according to results from a world-first international study into second-line human immunodeficiency virus (HIV) therapy. “This finding of non-inferiority has significant implications for the management of HIV globally,” commented Professor Matthew Law from the Kirby Institute.

105

105

STAT

FEBRUARY 20, 2023

Dan Brickey was stunned when he learned the news. The cost of the cystic fibrosis medicine that his 2-year-old daughter, Ali, had recently started taking was about to climb from just $180 out of pocket each year to a whopping $43,600 in 2023. The dramatic change was due to a decision by the drug’s manufacturer, Vertex Pharmaceuticals, to slash the amount of financial assistance that it offers to patients this year.

Drug Pricing 246

Drug Pricing 246

PharmExec

FEBRUARY 22, 2023

Sermo and LiveWorld survey of 50+ pharma marketers and 200+ physicians finds that social media plays a major role in influencing perceptions of medications, prescribing Habits, ongoing medical education and professional networking.

98

98

Pharma Times

FEBRUARY 21, 2023

Boost for effected patients as HEMGENIX receives green light from European Commission

138

138

European Pharmaceutical Review

FEBRUARY 22, 2023

Biologics represent an increasingly large part of the pharmaceutical industry. Of the 175 new drugs approved by the US Food and Drug Administration (FDA) between 2016 and 2019, most were biologics. 1 Used to treat a range of chronic diseases (eg, diabetes, rheumatoid arthritis, psoriasis, Crohn’s disease, haemophilia, etc), it is projected that the sales of biologics will rise from $380 billion in 2022 to $416 billion in 2023, and to almost $600 billion in 2027. 2 Most biotherapeutics are delive

Biosimilars 105

Biosimilars Diabetes Immunity Immunization 105