Sat.May 04, 2024 - Fri.May 10, 2024

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Farmers resist push for workers to wear protective gear against bird flu virus

STAT

WASHINGTON — The Centers for Disease Control and Prevention recommended this week that dairy and poultry farms with infected animals supply protective gear to workers in a bid to stave off human transmission of the H5N1 virus. The challenge now is making it happen. The CDC has no legal authority to order those protective measures, and health officials in some of the nine states with reported outbreaks in cattle have had little luck getting farmers to take them up on offers of free persona

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As drug shortages reach record highs, regulators float next steps

PharmaVoice

With many chemo and ADHD drugs stuck in stubborn shortages, several agencies are looking for new solutions to boost supplies.

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Trending Sources

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Hot off the press: Bridge to EM curriculum (2nd edition) released

ALiEM - Pharm Pearls

It has been 3 years since the 8-week, self-guided Bridge to Emergency Medicine (EM) curriculum was launched to help graduating medical students prepare for EM residency. The curriculum has been viewed over 43,000 times and we have awarded over 5,000 ALiEMU course certificates. It is now a part of many residency programs’ intern boot camp. Launching the 2nd edition of Bridge to EM (2024) We are thrilled to announce that we launching the second edition of the curriculum.

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Oregon and Lantern collaborate to develop drug candidate for various cancer indications

Pharma Times

Anticancer drugs will be responsible for 90% of nearly 612,000 predicted US cancer deaths in 2024

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Navigating Payroll Compliance: Future-Proofing Payroll in an Evolving Regulatory Landscape

Speaker: Jennifer Hill

Payroll compliance is a cornerstone of business success, yet for small and midsize businesses, it’s becoming increasingly challenging to navigate the ever-evolving landscape of federal, state, and local regulations. Mistakes can lead to costly penalties and operational disruptions, making it essential to adopt advanced solutions that ensure accuracy and efficiency.

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STAT+: Sanofi enters vaccine licensing deal with Novavax, giving beleaguered biotech a lifeline

STAT

LONDON — Novavax, the beleaguered maker of a Covid-19 vaccine, just got a boost of its own.   The French pharma company Sanofi on Friday said it had reached a licensing deal to sell Novavax’s Covid shot going forward as well as to try to combine the vaccine with Sanofi’s own flu shot. The pact includes a $500 million upfront payment, with up to $700 million more on the table if certain regulatory and launch milestones are reached.

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Revealed: key files shredded as UK government panic grew over infected blood deaths lawsuit

The Guardian - Pharmaceutical Industry

Lost documents prevented victims from finding out the truth, official inquiry told Disastrous failures that caused the contaminated blood scandal were denied by ministers for decades after officials destroyed, lost and blocked access to key documents, memos submitted to the official inquiry reveal. Several batches of files involving the work of a blood safety advisory committee were shredded as the government faced the threat of legal action, documents show.

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Chiesi and Gossamer collaborate to develop drug to treat respiratory diseases

Pharma Times

Gossamer’s seralutinib is designed to treat pulmonary arterial hypertension and other indications

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Federal officials will fund farms’ protective measures to contain H5N1 bird flu

STAT

WASHINGTON — The federal government will provide livestock farms as much as $28,000 apiece to bolster protective measures and testing for the avian flu virus spreading among dairy cows, officials said Friday. The Agriculture Department also allotted $98 million to aid states restricting the interstate movement of affected cattle, and health officials announced they would put an additional $101 million toward expanded surveillance, tests, treatments, and vaccines for the virus, which has n

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AZ oncology chief says AI can help solve cancer’s ‘ZIP code lottery’ as health disparities persist

PharmaVoice

Partnerships have been key to building the company’s AI capabilities and patient-focused R&D, said AstraZeneca’s head of U.S. oncology.

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From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

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Patient dies in Pfizer study of Duchenne gene therapy

BioPharma Dive

Pfizer said the patient, a young boy who was treated earlier last year, had died suddenly. The company is working with trial researchers to investigate further.

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NHS to roll out fibre optic laser therapy to prevent seizures in epileptic patients

Pharma Times

The chronic brain disease that causes seizures currently affects around 600,000 people living in the UK

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Bird flu keeps rewriting the textbooks. It’s why scientists are unsettled by the U.S. dairy cattle outbreak

STAT

Twenty-seven years ago today, a 3-year-old boy in Hong Kong developed a sore throat, spiked a fever, and started to cough. Six days later, he was hospitalized; six days after that, he died of acute respiratory distress caused by viral pneumonia. Testing showed the toddler, who’d had contact with sick chickens before becoming ill, had been infected with H5N1 bird flu.

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FDA’s new diagnostic rules draw pharma criticism

PharmaVoice

Tests frequently used in clinical trials will soon be regulated like medical devices — with some exceptions.

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Why Every Small Business Needs an HCM Solution: A Comprehensive Guide

Managing HR tasks like payroll, compliance, and employee data can overwhelm small businesses. That’s where a Human Capital Management (HCM) solution comes in. Our eBook, Why Every Small Business Needs an HCM Solution: A Comprehensive Guide , shows how an HCM system automates tedious processes, ensuring your business stays compliant and efficient. You’ll learn how to simplify payroll, eliminate costly errors, and empower your employees with self-service tools.

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Patients 'put at risk' as pharmacies face medicine shortages 'multiple times a day'

The Pharmacist

Eight in 10 pharmacy team members report that medicine shortages are putting patients’ health at risk, according to a survey by Community Pharmacy England (CPE). The Pressures Survey, completed by more than 900 pharmacy owners and over 2,000 pharmacy team members, found that medicine supply issues were affecting the majority of pharmacy teams (72%) ‘multiple […] The post Patients 'put at risk' as pharmacies face medicine shortages 'multiple times a day' appeared first o

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OneChain’s CAR T trial treats its first cortical T-cell ALL patient

Pharma Times

The subtype accounts for 20% of all T-cell leukaemias, a rare form of blood cancer which produces too many abnormal T-cells

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Large amount of bird flu virus in milk suggests asymptomatic cows are infected with H5N1

STAT

Since March, when the first reported cases of H5N1 bird flu began showing up in dairy cattle in Texas, the Food and Drug Administration has been asking farmers to discard any milk from infected animals. Initially, spotting tainted milk was believed to be fairly easy because cows that get sick with H5N1 begin producing milk that is thick and yellowish.

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The Enhertu effect: Daiichi’s plan to build on the success of its crown jewel

PharmaVoice

The CEO of Daiichi Sankyo’s American business explains how the company plans to build off the momentum of its blockbuster cancer med.

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Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

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Drug patents protect pharma profits. Track when they’ll expire here.

BioPharma Dive

Intellectual property is the foundation of the drug industry’s business model. This database will track key patent expiry dates for 30 top-selling medicines.

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Johns Hopkins scientists depict molecular pathway to track replication in cancer cells

Pharma Times

The findings could potentially lead to new therapies and could stop the growth of cancers

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STAT+: Gene therapy trial targeting rare form of deafness shows ‘jaw-droppingly good’ results

STAT

Two congenitally deaf children can hear for the first time after being treated with gene therapy, according to data presented at a conference Wednesday. The results are “jaw-droppingly good, just shocking how good. It exceeded the wildest expectations of anybody who started this work,” said Larry Lustig, an otolaryngologist at Columbia University and an investigator on the study.

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Lilly’s donanemab will face an Alzheimer’s adcomm in June, setting the stage for a Leqembi showdown

PharmaVoice

The FDA announced a June advisory committee date, potentially introducing a new Alzheimer’s treatment to compete with Eisai and Biogen’s Leqembi.

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Best Practices to Streamline Compensation Management: A Foundation for Growth

Speaker: Joe Sharpe and James Carlson

Payroll optimization can be one of the most time-consuming and complex factors of small business management. Yet, organizations that crack the code on streamlining employee compensation often discover innovative avenues for growth. With the right strategies in place, outsourcing and streamlining payroll processes can result in substantial time and resource savings.

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Regeneron gene therapy restores hearing in deaf child

pharmaphorum

Regeneron’s gene therapy for otoferlin-related hearing loss restored hearing to normal levels in one profoundly deaf child within just 24 weeks

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Francis Crick Institute and Broken String Biosciences partner for ALS research

Pharma Times

The rare and fatal progressive neurodegenerative disease is estimated to affect 5,000 people in the UK

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Opinion: It shouldn’t be easy to buy synthetic DNA fragments to recreate the 1918 flu virus

STAT

It should be hard — exceedingly hard — to obtain the synthetic DNA needed to recreate the virus that caused the deadly 1918 influenza pandemic without authorization. But my lab found that it’s surprisingly easy, even when ordering gene fragments from companies that check customers’ orders to detect hazardous sequences. Our experiment demonstrates that the immense potential benefits of biotechnology are profoundly vulnerable to misuse.

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Potential best-in-class antibody shows “remarkable efficacy” in atopic dermatitis

European Pharmaceutical Review

New data from a Phase IIa trial in moderate-to-severe atopic dermatitis has demonstrated that a novel monoclonal antibody (mAb) could facilitate dosing every 12 weeks for induction therapy. This is due to a 31-day half-life at anticipated therapeutic dose levels, Inmagene Biopharmaceuticals confirmed. Humanised anti-OX40 IgG1 mAb IMG-007 works via a silenced antibody -dependent cellular cytotoxicity (ADCC) function, Inmagene explained.

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Enhance Healthcare Efficiency With Top Payroll & HCM Services

Running a healthcare facility requires precision and care, not just for patients but also for your staff. Our guide, "A Buyer’s Guide to Payroll & HCM Services," helps healthcare providers choose the best provider. Efficient payroll management ensures timely, accurate payments, critical for maintaining staff morale and trust. Compliance support helps navigate complex healthcare regulations and avoid costly fines.

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Spectral AI nears first sales of wound care system

pharmaphorum

The first commercial sales of Spectral AI's DeepView wound imaging system for burns are due to start in the UK, its first market, later this year

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NHS reduces long waits for cancer care and achieves faster ambulance responses

Pharma Times

For the second month in a row, the NHS has met the 28-day faster diagnosis target for cancer

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STAT+: No, alcohol isn’t good for you. Will new dietary guidelines be shaped more by health or industry interests?

STAT

In 1995, when Marion Nestle was on the committee drafting the Dietary Guidelines for Americans, things were run differently. She and other experts handled it all: deciding on nutrition-related research questions, collecting the evidence, issuing a scientific report, and then writing guidance for how Americans should eat. When it came time for that last part — the writing — Nestle and two co-authors got together at a bar, ordered glasses of wine, and got to work.