Sat.Jul 27, 2024 - Fri.Aug 02, 2024

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Opinion: The coronavirus lab leak hypothesis is damaging science

STAT

Where and when the Covid-19 pandemic began — in Wuhan, China in late 2019 — is well known. How it began is a matter of heated controversy. There are two competing hypotheses, one of which is hindering the process of scientific discovery and could hold back the development of vaccines and other antiviral agents in the U.S. The zoonosis hypothesis proposes that SARS-CoV-2, the virus that causes Covid-19, was naturally transmitted from an animal to one or more humans in a so-called we

Vaccines 363
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Read to lead: 6 books pharma execs swear by

PharmaVoice

From an epic, alternative reality fantasy to a ‘biography of cancer,’ these six reads have stuck with pharma execs as they navigate how to lead.

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Pharmacy contract delays causing 'stress, uncertainty and closures'

The Pharmacist

More and more pharmacies are closing as a six-month delay to the community pharmacy contract means core funding has still not been uplifted since 2019. Contractors told The Pharmacist that they struggle to keep up with increased demand for services and the knock-on impact of pressure elsewhere in the health system, while being unable to pay their […] The post Pharmacy contract delays causing 'stress, uncertainty and closures' appeared first on The Pharmacist.

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Frontiers Health 2024: Connecting changemakers, cultivating health system change

pharmaphorum

Frontiers Health 2024 is a platform connecting innovators and changemakers in the life sciences industry to cultivate positive changes in health systems. Discover the latest trends and insights in healthcare innovation.

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From Payroll Pains to Growth Gains: Streamlining Payroll & HR for Success

Speaker: Joe Sharpe and James Carlson

In the world of small business management, the challenge of managing payroll & HR efficiently while scaling operations can be overwhelming. Yet, with the right strategies in place, these challenges can become opportunities for growth and innovation. In this session, Joe Sharpe, Senior Director of Managed Payroll Services at IRIS, will reveal practical methods and expert insights for outsourcing and streamlining payroll processes, resulting in substantial time and resource savings.

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Behind the malaria vaccines: A 40-year quest against one of humanity’s biggest killers

STAT

Malaria is one of our most ancient foes — and one of the wiliest. Caused by parasites that certain mosquitoes spread through their bites, malaria overwhelms us, establishing an infection before we can put up a fight. It can go on to destroy red blood cells, batter organs, and even damage the brain.

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3 Big Pharma cancer drugs facing inflation penalties

PharmaVoice

The U.S. government will demand payment from Big Pharma to make up for dozens of drugs with prices that rose faster than the rate of inflation.

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Lilly gets first heart outcomes readout with tirzepatide

pharmaphorum

Eli Lilly's dual GLP-1/GIP agonist tirzepatide has been shown to reduce the risk of worsening disease in people with heart failure and obesity in a phase 3 trial, the first to show a benefit on cardiovascular outcomes with the drug.

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STAT+: Mount Sinai mounted aggressive campaign to stifle debate over revelations about its controversial brain research

STAT

Mount Sinai, a leading hospital network in New York City, has mounted an extraordinary behind-the-scenes campaign to blunt the fallout over revelations about its controversial research project in which brain biopsies are taken from patients undergoing deep brain stimulation, STAT has learned. That has included not only enlisting its own patients to defend the research but also seeking to stop a professional society of neurosurgeons from issuing a statement that could have jeopardized the researc

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What pharma has learned from AI

PharmaVoice

As AI tools move from hype to a daily reality at pharma companies, here are the insights users are gaining.

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Pfizer quits Duchenne gene therapy, lays off staff following study setback

BioPharma Dive

The company is letting go of 150 staffers alongside a decision to officially terminate the high-profile program, which was acquired in 2016.

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Enhance Healthcare Efficiency With Top Payroll & HCM Services

Running a healthcare facility requires precision and care, not just for patients but also for your staff. Our guide, "A Buyer’s Guide to Payroll & HCM Services," helps healthcare providers choose the best provider. Efficient payroll management ensures timely, accurate payments, critical for maintaining staff morale and trust. Compliance support helps navigate complex healthcare regulations and avoid costly fines.

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A symbiotic relationship for optimal AI-powered healthcare

pharmaphorum

Discover how OPEN Health and fusion's AI technology partnership is creating a symbiotic relationship that is revolutionising healthcare. Explore the benefits of this for optimal patient care.

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STAT+: Sarepta demanded Duchenne patient advocacy group censor video critical of the company

STAT

Sarepta Therapeutics demanded a prominent patient advocacy organization censor a video that contained pointed criticism of the company’s recently approved gene therapy for Duchenne muscular dystrophy, STAT has learned. The incident raises questions about the financial ties between Sarepta and the advocacy group, Parent Project Muscular Dystrophy, and whether the drugmaker uses its money to influence, or even muzzle, debate over its Duchenne medicines.

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Lowest summer registration pass rate in four years

The Pharmacist

The number of students passing the summer pharmacist registration exam is the lowest it has been in four years, figures published today have revealed. Just 75% of trainee pharmacists passed the common registration assessment for pharmacists this year, held jointly by the General Pharmaceutical Council (GPhC) and Pharmaceutical Society of Northern Ireland (PSNI).

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Rainwater Foundation, CurePSP, Aging Mind Foundation fund innovative tauopathy research

Outsourcing Pharma

The Rainwater Charitable Foundation (RCF), in collaboration with CurePSP and the Aging Mind Foundation (AMF), has announced the allocation of $2 million in grants to support groundbreaking research in primary tauopathies.

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Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

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Changing Faces: May and June 2024 supplier and digital hires

pharmaphorum

Changing Faces announces new supplier and digital hires for May and June 2024, including AxoSim, ERS Genomics, Newcells Biotech, SHINE Technologies and more. Stay updated with the latest industry developments.

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STAT+: In a big step for liquid biopsy, FDA approves a blood test for colorectal cancer

STAT

The Food and Drug Administration on Monday approved a blood test intended to detect colon cancer, a product many experts hope will help catch cases of the disease early enough so that they can be more easily treated. The test, called Shield and made by Guardant Health, a Palo Alto, Calif.-based biotech firm, comes with a drawback: It is not as good as a colonoscopy and other tests at detecting precancerous or early stage cancers.

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Eco HPLC-based method shows promise for Z-alkene synthesis

European Pharmaceutical Review

Japanese researchers have developed a new method for photoisomerisation of E -cinnamamides to Z -cinnamamides. The approach uses a recycling photoreactor coupled with a high-performance liquid chromatography (HPLC) system. As organic compounds, many Z -alkenes “cannot be prepared through conventional methods involving thermodynamic methods”. On the other hand, “photoisomerisation can offer good yields”, they noted.

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Lilly obesity drug shows heart benefit in late-stage trial

BioPharma Dive

The drug led to a 38% reduction in the risk of death or complications from a type of heart failure, a finding that compared favorably to available treatments.

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5 Reasons to Upgrade Your Pharmacy Management Software

Are you still using workarounds to manage your daily operations? To achieve peak performance, it's time to explore other options for specialty and infusion pharmacy software. Streamline pharmacy operations and improve clinical performance with automated processing, real-time data exchange, and electronic decision support. Download this helpful infographic to: Drive efficiency and patient adherence from referral receipt to delivery and ongoing care – all with our Pharmacy Cloud.

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Changing Faces – Pharma and biotech May and June 2024

pharmaphorum

Stay updated on the latest hiring news and developments from Pfizer, Lilly, Gilead, Epsilogen, and other pharma and biotech companies in May and June 2024 with Changing Faces.

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STAT+: Dental AI startup raises $30 million, including from Mark Zuckerberg’s dad

STAT

As the AI race in dentistry grows more heated, a startup called Perceptive is aiming to automate each stage of a dental visit, from imaging to treatment recommendations to the actual surgical procedure. The Boston startup, which recently came out of stealth mode, announced on Tuesday that it has received $30 million in funding to work on a dental system that includes a hand-held imaging machine, an AI algorithm to help diagnose and suggest treatment, and a surgical robot to complete the procedur

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Vizient projects drug price inflation at 3.81%

vizient

The report points to expanding indications of previously approved medications, such as semaglutide, as partial cause for the projected increase. It also urges providers to prepare for an increased number of high-cost cell and gene therapies entering the market that will significantly impact provider budgets and operational processes.

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First-of-its-kind cell therapy approved by FDA for rare soft tissue cancer

BioPharma Dive

Adaptimmune’s Tecelra is the first TCR cell therapy to reach market and, at $727,000, is also the priciest cellular medicine for cancer in the U.S.

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Going beyond the hype: Embracing AI for strategic advantage

pharmaphorum

Discover how AI is revolutionising the medical and pharmaceutical industries. Learn how to leverage AI for strategic advantage and stay ahead of the competition in this insightful article.

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Could cow vaccines help halt the spread of bird flu in U.S. herds? Experts are divided

STAT

With the number of U.S. dairy herds infected with H5N1 bird flu rising almost daily, fears are growing that the dangerous virus cannot be driven out of this species. That belief is amplifying calls for the development of flu shots for cows. Multiple animal vaccine manufacturers are reportedly at work trying to develop such products. And the U.S. Department of Agriculture is eagerly encouraging the effort, detailing in a notice last week what kinds of evidence would be needed to win licensing app

Vaccines 362
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'MHRA set to streamline UK medical device approvals'

The Pharmacist

An MHRA statement of policy intent is designed to recognise approvals from specific foreign territories and to simplify and speed-up the regulatory process for medical devices. Thorrun Govind, solicitor (Brabners LLP), pharmacist and TV health expert, explains what this means. Framework for medical device approvals Under the new MHRA proposed framework for international recognition of […] The post 'MHRA set to streamline UK medical device approvals' appeared first on The Pharmaci

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Moderna shares fall amid lower sales outlook for RSV, COVID shots

BioPharma Dive

The biotech cited competitive pressure and “very low” expected sales in Europe for its latest guidance cut, which sent shares down by nearly 20%.

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South Africa's HIV Research: Unlocking the mysteries of elite controllers

pharmaphorum

South Africa occupies a pivotal position in the global battle against HIV. As of 2022, it is home to around 7.8 million individuals living with HIV, representing the largest HIV burden in the world. However, it is this very challenge that has placed South Africa at the leading edge of innovative HIV research, with potential ramifications for the millions affected by the disease globally - and that starts with elite controllers.

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CDC will offer seasonal flu shots to farmworkers to lower bird flu risk

STAT

The Centers for Disease Control and Prevention announced Tuesday that it is funding a $5 million program to vaccinate livestock industry workers against seasonal flu in a bid to reduce the pandemic risk posed by the ongoing H5N1 bird flu outbreak in cattle. The voluntary program, which will be administered by state and local public health workers, is aimed at getting seasonal flu shots into as many people as possible who are working in proximity to animals — poultry, cows, or other livest

Vaccines 362
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'Outrageous' £9m monthly clawbacks after DHSC error

The Pharmacist

The Department of Health and Social Care (DHSC) will reduce Category M prices by £9m per month because it erroneously increased reimbursement prices in July. Community Pharmacy England (CPE) said that 'based on erroneous calculations' regarding market movements of wholesale prices, in July the DHSC implemented an increase in Category M reimbursement of approximately £21m […] The post 'Outrageous' £9m monthly clawbacks after DHSC error appeared first on The Pharmacist.

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Researchers reveal CAR-enhancer therapy could help overcome cancer relapse

Pharma Times

Cancer is estimated to affect more than three million people living in the UK, according to Macmillan Cancer Support

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UK partnership aims to support NHS use of depression app

pharmaphorum

Otsuka has teamed up with one of the innovation arms of the NHS to explore how a digital therapeutic (DTx) for major depressive disorder (MDD) could be deployed within the health service.The alliance with Health Innovation Oxford & Thames Valley (Oxford HIN) is focusing on Care for MDD, an app-based DTx that has been co-developed by Otsuka and digital health specialist Click Therapeutics.

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STAT+: Older GLP-1 drug may help protect brains of Alzheimer’s patients, early study suggests

STAT

A new study suggests that an older GLP-1 drug may help protect the brains of people with early Alzheimer’s disease, supporting the case for further research on the class of medications — originally developed for obesity and diabetes — in neurological diseases. The Phase 2 randomized trial, led by researchers at Imperial College London, tested Novo Nordisk’s liraglutide, the predecessor to Ozempic and Wegovy, in patients with early Alzheimer’s disease over one y

Diabetes 360
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Discover the latest digital solutions that promise to revolutionize mental health care

Outsourcing Pharma

In a significant development for mental health treatment, experts from the University of Oxfordâs Departments of Experimental Psychology and Psychiatry have introduced four innovative online therapies.

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