Sat.Feb 17, 2024 - Fri.Feb 23, 2024

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Florida policy set amid measles outbreak alarms vaccination proponents

STAT

A Florida state policy set amid a measles outbreak in Broward County has vaccination proponents aghast, with many saying it leaves unvaccinated children especially vulnerable to the highly contagious disease. In a letter dated Tuesday about an outbreak at Manatee Bay Elementary School in Weston, located northwest of Miami and west of Fort Lauderdale, the state’s surgeon general, Joseph Ladapo, said that while it is normal policy to tell unvaccinated children to stay home during an outbrea

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For Moderna, COVID vaccines were a ‘proof of concept’ — now comes the big test

PharmaVoice

Following Moderna’s COVID-19 vaccine success, therapeutics head Dr. Kyle Holen discusses scaling mRNA development to bring candidates to the finish line in oncology and more.

Vaccines 265
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ACMT Toxicology Visual Pearl: Salt, not Shock

ALiEM - Pharm Pearls

What agent would most likely be responsible for these ECG findings? Cyclobenzaprine Digoxin Flecainide Sotalol Reveal the Answer 3. Flecainide Background [1-3] Flecainide is a class IC antiarrhythmic that binds to the voltage-gated sodium channel of the myocardium, slowing depolarization and prolonging phase 0 of the action potential. In toxicity, bradydysrhythmias, AV nodal blockade, ventricular tachycardia, and rate-dependent QRS widening occur.

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The opportunities and challenges facing rare disease therapies developers

pharmaphorum

Explore the opportunities and challenges facing rare disease therapies developers, including the impact of Rare Disease Day, FDA regulations, and cutting-edge technologies like CRISPR gene therapy.

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From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

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Presidential age debate obscures a simple fact: Some cognitive skills improve as we get older

STAT

When a psychology professor in Michigan looked through his data on interpersonal conflict a decade ago, he discovered something unexpected. The study , which examined differences across cultures and age groups, seemed to show Americans got wiser as they got older. Richard Nisbett was used to research showing poorer mental skills among elderly adults, but his work found they were better at recognizing multiple perspectives, encouraging compromise, and acknowledging the limits of their own knowled

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Value and potential of IoT and AI for chronic diseases treatment

PharmaVoice

A significant growth is predicted for both AI and IoT in healthcare. By 2030, the AI market is expected to reach $187.95 billion USD, while the IoT market is projected to climb even higher to $312.7 billion USD.

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More Trending

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Roche’s Xolair is first medicine for food allergy in US

pharmaphorum

Fast approaching the end of its patent life, Roche and Novartis’ Xolair is going out with a bang, picking up a new approval as the first and only drug therapy for people with food allergies in the US.

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Opinion: The Alabama IVF ruling uses faux scientific language to justify a religious position

STAT

Imagine having 15 miscarriages. Maybe you can shrug off the first one or two and keep trying to have children, to create a family. But soon every positive pregnancy test brings a sense of dread, of sad inevitability. Your body becomes your enemy.

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Behind the breakthrough cancer therapy that just won a historic FDA nod

PharmaVoice

The first-of-its-kind TIL therapy for solid tumors developed by Iovance Biotherapeutics won FDA approval last week.

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Iovance, with approval of ‘TIL’ cell therapy, readies for complex launch

BioPharma Dive

The biotech set a price of roughly $515,000 per patient for its therapy Amtagvi, the first to be approved based on a decades-old technique of using tumor-infiltrating lymphocytes.

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Why Every Small Business Needs an HCM Solution: A Comprehensive Guide

Managing HR tasks like payroll, compliance, and employee data can overwhelm small businesses. That’s where a Human Capital Management (HCM) solution comes in. Our eBook, Why Every Small Business Needs an HCM Solution: A Comprehensive Guide , shows how an HCM system automates tedious processes, ensuring your business stays compliant and efficient. You’ll learn how to simplify payroll, eliminate costly errors, and empower your employees with self-service tools.

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Transforming clinical data management systems for biotechnology trials

pharmaphorum

Learn how biotechnology trials are transforming clinical data management systems, leveraging machine learning and advanced protocols to enhance efficiency and accuracy in data collection and analysis.

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NIH study of ME/CFS points to immune dysfunction and brain abnormalities at core of long-dismissed disease

STAT

Alison Sbrana was in the belly of an opera when her life changed. Down in the pit, surrounded by fellow orchestra members, she’d been straining to play her flute for half the show. As performers overhead enveloped the audience in arias, Sbrana felt like the Hulk was pulling on the tendons in the right side of her neck. “I begged anybody for meds at intermission,” she said.

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Kite’s next-gen CAR-T aims include quicker production and more disease targets

PharmaVoice

While buzz builds around “off the shelf” CAR-T cell therapies, Kite is staying competitive with a shorter manufacturing turnaround and a focus on broadening applications.

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Frontier gets $80M, Galapagos’ backing to make a better KRAS drug

BioPharma Dive

The startup’s Series C round will support a clinical-stage drug the company thinks could address some of the weaknesses of other KRAS-targeting medicines.

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Best Practices to Streamline Compensation Management: A Foundation for Growth

Speaker: Joe Sharpe and James Carlson

Payroll optimization can be one of the most time-consuming and complex factors of small business management. Yet, organizations that crack the code on streamlining employee compensation often discover innovative avenues for growth. With the right strategies in place, outsourcing and streamlining payroll processes can result in substantial time and resource savings.

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AbbVie’s 24-hour Parkinson’s therapy to roll out on NHS

pharmaphorum

Around 1,000 people with Parkinson’s in England will be able to access treatment with AbbVie’s Produodopa, the first therapy delivered by a 24-hour subcutaneous infusion pump

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Meet the fetal surgeon forging CRISPR’s next frontier: curing diseases in the womb

STAT

SAN FRANCISCO — Outside, the August sun wasn’t yet visible through the thick folds of fog blanketing the San Francisco skyline. Its warmth did not reach the operating room tucked into the sprawling Parnassus Heights hospital complex. In there, the light was all cold and blue fluorescence washing over the sea of scrub caps huddled around an anesthetized young woman on a gurney.

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4 biotechs to watch in 2024

PharmaVoice

A splashy IPO, first-in-class treatments and upcoming approval dates are a few reasons we’ve got our eyes on these biotechs this year.

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BioMarin preaches patience amid slow sales for hemophilia gene therapy

BioPharma Dive

The company earned only $3.5 million last year from its Roctavian treatment, far below the $50 million to $150 million range it had forecast eight months ago.

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Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

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Clinical research is about trial and error

pharmaphorum

Clinical research involves trial and error as part of the drug development process. Learn more about how to optimise drug trials and the important role of participants in clinical research.

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Small study adds to growing hope CAR-T cell therapy could revolutionize autoimmune disease treatment

STAT

People with autoimmune disorders don’t usually get to talk about a cure. There’s symptom management, hopeful periods of remission often followed by relapses, but rarely a lasting fix for the way their immune system attacks healthy cells. If the immune system is an army, then those with conditions like lupus, multiple sclerosis, or rheumatoid arthritis are often fighting a never-ending war of friendly fire.

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UKHSA investigating rise in tuberculosis cases

The Pharmacist

The UK Health Security Agency (UKHSA) is investigating what is behind an 11% rise in tuberculosis cases in England last year. There were 4,850 tuberculosis cases in 2023 compared to 4,380 in 2022, representing a jump of 10.7%, according to provisional data. Even before the Covid-19 pandemic, TB incidence was lower than this, with 4,615 […] The post UKHSA investigating rise in tuberculosis cases appeared first on The Pharmacist.

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Long-Acting Injectable Cabenuva Found More Effective Than Daily ART at Suppressing HIV in Patients With Adherence Challenges

Pharmaceutical Commerce

Cabenuva (cabotegravir + rilpivirine) showed superior efficacy in maintaining viral load suppression in patients with HIV compared with standard of care daily oral antiretroviral treatment.

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Enhance Healthcare Efficiency With Top Payroll & HCM Services

Running a healthcare facility requires precision and care, not just for patients but also for your staff. Our guide, "A Buyer’s Guide to Payroll & HCM Services," helps healthcare providers choose the best provider. Efficient payroll management ensures timely, accurate payments, critical for maintaining staff morale and trust. Compliance support helps navigate complex healthcare regulations and avoid costly fines.

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FDA starts review of Argenx drug in rare disease CIDP

pharmaphorum

The FDA has said it plans to deliver a decision in June on the use of Argenx’ Vyvgart Hytrulo in rare autoimmune disease chronic inflammatory demyelinating polyneuropathy (CIDP).

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STAT+: UnitedHealth cyberattack cripples pharmacies’ and hospitals’ ability to process insurance claims

STAT

Hospitals, pharmacies, and other health care providers are getting stuck in an insurance processing logjam after UnitedHealth Group disclosed a cyberattack within a recently acquired subsidiary that serves as a central hub for payments across the industry. The cyberattack and subsequent system outage within UnitedHealth’s Change Healthcare has caught the attention of federal law enforcement agencies.

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Only half of pharmacists enjoy their work, survey suggests

The Pharmacist

Just 52% of pharmacists enjoy ‘some aspects’ of their work or study, a new wellbeing survey from the Royal Pharmaceutical Society (RPS) and charity Pharmacist Support has found. And nearly nine in 10 pharmacists are at high risk of burnout, the survey suggested, prompting calls to address the underlying factors contributing to poor mental health […] The post Only half of pharmacists enjoy their work, survey suggests appeared first on The Pharmacist.

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Celebrating Thank a Resident Day 

Board Vitals - Pharmacist

Medical residents play an important role in healthcare, from providing patient care to conducting research and collaborating with healthcare teams. To honor residents and their contributions and sacrifices, we celebrate Thank a Resident Day—a day dedicated to expressing gratitude for these remarkable individuals. What is Thank a Resident Day? Medical residency is a demanding journey filled with long hours, challenging cases, and constant learning.

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5 Reasons to Upgrade Your Pharmacy Management Software

Are you still using workarounds to manage your daily operations? To achieve peak performance, it's time to explore other options for specialty and infusion pharmacy software. Streamline pharmacy operations and improve clinical performance with automated processing, real-time data exchange, and electronic decision support. Download this helpful infographic to: Drive efficiency and patient adherence from referral receipt to delivery and ongoing care – all with our Pharmacy Cloud.

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Case Study: MGI and Alacris Theranostics

pharmaphorum

This case study explores the collaborative efforts of MGI and Alacris Theranostics in utilising molecular tumour profiling technology for advanced research. Discover the impact of this innovative approach on personalised medicine and treatment strategies.

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‘All of Us’ reports half of the genomes it has sequenced are from non-Europeans

STAT

Six years ago, the National Institutes of Health placed its biggest ever bet on precision medicine, launching a study to enroll over 1 million participants in an ambitious data-gathering gambit unmatched in its scope and diversity. Since then, Americans from all walks of life have been showing up and handing over their blood, spit, and pee to the project, dubbed “All of Us.

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EGFR inhibitor could provide major advance in lung cancer

European Pharmaceutical Review

Small molecule treatment TAGRISSO ® (osimertinib) demonstrated a “statistically significant and highly clinically meaningful improvement” in progression-free survival (PFS) for Stage III lung cancer patients, AstraZeneca has confirmed. This was established from positive high-level results seen in the LAURA Phase III trial. The data was based on observations from patients with unresectable, Stage III epidermal growth factor receptor-mutated (EGFRm) non-small cell lung cancer (NSCLC) after chemor

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Codeine linctus reclassified to prescription-only amid addiction risk

The Pharmacist

Codeine linctus has been reclassified to a prescription-only medicine (POM) following concerns it was being used recreationally for its ‘opioid effects’, the Medicines and Healthcare products Regulatory Agency (MHRA) has announced. The cough syrup, which is indicated for dry cough and contains the opioid painkiller codeine, was previously a Pharmacy (P) status medicine.

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Bavarian Nordic gets swift EU review of chikungunya shot

pharmaphorum

Bavarian Nordic will get an accelerated review of its chikungunya vaccine CHIKV VLP at the EMA, as it tries to chase down a lead held by rival Valneva. The Danish pharma group said it is planning to file for approval of its vaccine in the first half of this year, adding the EU regulator’s human medicine committee, the CHMP, has said it will cut the review time from 210 to 150 days under its accelerated assessment procedure.

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