Sat.Jan 27, 2024 - Fri.Feb 02, 2024

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Is Pharmacy Ownership for You? +4 Points to Consider

PioneerRx

There are many ladders to climb in the pharmacy industry. Clerks can become techs, techs can be lead techs, and lead techs can be pharmacists.

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Updated Covid vaccine has 54% effectiveness, new data suggest

STAT

New data released Thursday by the Centers for Disease Control and Prevention suggest that the most recent Covid-19 booster offers about 54% percent protection against infection with the virus. A study published in the CDC’s online journal Morbidity and Mortality Weekly Report showed that the updated vaccine was essentially equally effective at protecting against the strain targeted by the vaccine — called XBB.1.5 — and the JN.1 subvariant, which emerged after the vaccin

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Immunotherapy changed the cancer treatment landscape. Is the gut microbiome the next frontier?

PharmaVoice

The president of L.A.’s City of Hope Cancer Center believes the current state of cancer treatments can be greatly improved with a peek into the gut’s many mysteries.

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SAEM Clinical Images Series: Back Lesion

ALiEM - Pharm Pearls

An 18-year-old-female with no known past medical history presented with a lesion on her back that had been present and enlarging for five months. It was not painful unless she touched it, and then only mildly tender. She denied any known cause, wound, prior rash, or other lesions. Her review of systems and past medical history were negative. Additional Images Physical Exam Vitals : Normal Skin : An erythematous lenticular, or biconvex, lesion with distinct borders is noted at the left posterior

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From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

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CAR-T for lupus: the ‘tip of the iceberg’ for cell therapy in autoimmune disease

BioPharma Dive

Since a landmark paper in 2022, drugmakers have begun nearly a dozen trials of cell therapies for lupus, with more set to start. Here’s why their efforts are worth watching.

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Scientists document first-ever transmitted Alzheimer’s cases, tied to no-longer-used medical procedure

STAT

LONDON — There was something odd about these Alzheimer’s cases. Part of it was the patients’ presentations: Some didn’t have the classic symptoms of the condition. But it was also that the patients were in their 40s and 50s, even their 30s, far younger than people who normally develop the disease. They didn’t even have the known genetic mutations that can set people on the course for such early-onset Alzheimer’s.

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Merck is on the lookout for more opportunities within immunology

Pharmaceutical Technology

At the JP Morgan Healthcare conference, Merck (MSD) indicated its eagerness to continue to establish its place in the immunological space.

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AstraZeneca, Daiichi aim for first pan-tumor ADC approval

BioPharma Dive

The FDA is reviewing the companies’ application for a “tumor agnostic” indication for their drug Enhertu, which would break new ground for antibody-drug conjugates.

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Opinion: I’m an anesthesiologist. Kenneth Smith’s execution by nitrogen gas was far from ‘textbook’

STAT

On Thursday evening, the state of Alabama executed Kenneth Eugene Smith by nitrogen gas. Now, there are dueling narratives about what happened. Alabama claims it went perfectly, proving that nitrogen is a humane, effective alternative to lethal injection (which it previously tried, unsuccessfully, to use on Smith). It says that based on this experience, other states should follow its example.

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Tonix closes in on the first new fibromyalgia drug in more than a decade

PharmaVoice

In addition to the chronic disease, the non-opioid drug may have applications in other painful conditions.

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Why Every Small Business Needs an HCM Solution: A Comprehensive Guide

Managing HR tasks like payroll, compliance, and employee data can overwhelm small businesses. That’s where a Human Capital Management (HCM) solution comes in. Our eBook, Why Every Small Business Needs an HCM Solution: A Comprehensive Guide , shows how an HCM system automates tedious processes, ensuring your business stays compliant and efficient. You’ll learn how to simplify payroll, eliminate costly errors, and empower your employees with self-service tools.

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JP Morgan 2024 – Gene Kinney

pharmaphorum

In this exclusive interview, Gene Kinney, CEO of Prothena, discusses the latest developments in the field of neurodegenerative diseases such as Alzheimer's and Parkinson's. Gain insights and advancements being made in the treatment of these conditions.

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Non-opioid drug from Vertex cuts pain in major trial tests

BioPharma Dive

The company plans to soon ask the FDA for approval of the drug, which it has pitched as a safer alternative to addictive opioid painkillers.

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STAT+: AI therapy and ICU training: A first look at health apps for Apple Vision Pro

STAT

Apple Vision Pro, the company’s most important new product in a decade, promises to envelop consumers in an immersive world of interactive content while employing clever technologies to make the device more usable and less alienating than virtual reality headsets that have come before it. Marketing for Vision Pro has focused on the $3,499, 1.3-pound helmet’s potential for watching video, making work calls, viewing family photos, and other casual uses.

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The Path for Prescription Drug Sales

Pharmaceutical Commerce

A dive into this market reveals that the latest numbers yield promising results—a global value of a worldwide $1.6 trillion—but it will continue to be attributed to past, present, and future healthcare spending.

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Best Practices to Streamline Compensation Management: A Foundation for Growth

Speaker: Joe Sharpe and James Carlson

Payroll optimization can be one of the most time-consuming and complex factors of small business management. Yet, organizations that crack the code on streamlining employee compensation often discover innovative avenues for growth. With the right strategies in place, outsourcing and streamlining payroll processes can result in substantial time and resource savings.

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First impressions matter: Why getting your onboarding right is key for digital engagement

pharmaphorum

Creating a positive onboarding experience is crucial for engaging healthcare professionals (HCPs) in digital platforms and utilising data effectively. Discover why first impressions matter and how to get your onboarding process right for optimal digital engagement.

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FDA clears IND for Gracell Biotechnologies’ phase 1 clinical trial for multiple myeloma treatment

Pharmafile

Gracell Biotechnologies has announced that the US Food and Drug Administration (FDA) has cleared its Investigational New Drug (IND) application, which allows them to initiate a phase 1 trial of GC012F in the US for the early-line treatment of multiple myeloma (ELMM). GC012F is “an autologous CAR T therapeutic candidate dual-targeting B cell maturation antigen […] The post FDA clears IND for Gracell Biotechnologies’ phase 1 clinical trial for multiple myeloma treatment appeared first on Pha

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We’re naming cancers all wrong, oncology leader says

STAT

Naming cancers solely by the organs they originate in is getting a bit old, according to Fabrice André, a medical oncologist at Gustave Roussy in France and the president-elect of the European Society of Medical Oncology. Instead, André hopes to push for a new naming system that emphasizes the molecular characteristics of a cancer, regardless of its tissue of origin.

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FDA Can’t Reclassify Its Way Out of Reviewing 100,000 LDT Submissions

FDA Law Blog: Biosimilars

By Steven J. Gonzalez & Allyson B. Mullen — On January 31, 2024, FDA announced its intent to initiate the reclassification process for most in vitro diagnostic (IVD) products that are currently class III (high risk) into class II (moderate risk). Most of these reclassified tests will supposedly be infectious disease and companion diagnostic IVDs.

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Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

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Pharmacies to deliver first private Covid vaccinations

The Pharmacist

Independent community pharmacies across the UK will begin offering private Covid vaccinations this spring, services provider Pharmadoctor has announced. For pharmacies that sign up for Pharmadoctor’s a patient group direction (PGD) package from today, the Nuvaxovid XBB.1.5 dispersion for injection vaccines will be available by 1 April 'at the latest', the company said today.

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In-person, hybrid, or digital? State of pharma meetings and events in 2024

pharmaphorum

Explore the current state of pharmaceutical meetings and events in 2024, including the shift from in-person to virtual and hybrid formats. Discover how the industry is embracing diversity, equity, and inclusion in these gatherings.

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Some dementia patients might have reversible symptoms caused by cirrhosis, study says

STAT

The descent into dementia can feel like traversing a minefield, coming across new symptoms without the hope of a cure. But some dementia patients, even up to 10% of people diagnosed with the condition, might actually have undiagnosed liver disease and accompanying neurological problems, a new study in JAMA Open Network suggests. Most importantly, it’s possible their liver-related brain symptoms could be resolved with treatment.

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Pharmaceutical industry: 2023 in retrospect

European Pharmaceutical Review

N-Nitrosamines By far the biggest issue bedevilling industry during 2023 was the continuing N-nitrosamine contamination saga, which was covered in the third issue of EPR 2023. 1 Some five years after the initial NDMA (N-nitrosodimethylamine) contamination issue 2 initially affecting valsartan drug substance, then other active pharmaceutical ingredients (APIs), eg, sartans, ranitidine, metformin, etc; the toxic short alkyl chain N-nitrosamine issue appears, if not resolved, then well on the way t

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Enhance Healthcare Efficiency With Top Payroll & HCM Services

Running a healthcare facility requires precision and care, not just for patients but also for your staff. Our guide, "A Buyer’s Guide to Payroll & HCM Services," helps healthcare providers choose the best provider. Efficient payroll management ensures timely, accurate payments, critical for maintaining staff morale and trust. Compliance support helps navigate complex healthcare regulations and avoid costly fines.

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Work together to implement new safety measures for valproate

The Pharmacist

Dr Alison Cave, chief safety officer at the Medicines and Healthcare products Regulatory Agency (MHRA), asks healthcare professionals to work together to better protect patients from the unnecessary harms of valproate, and to prescribe safer alternatives. New guidance was launched on 31 January The teratogenic effects of valproate, prescribed in the UK to treat epilepsy […] The post Work together to implement new safety measures for valproate appeared first on The Pharmacist.

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Lundbeck study knocks confidence in alpha-syn as CNS target

pharmaphorum

A phase 2 trial of Lundbeck’s alpha-synuclein-targeting drug Lu AF82422 has failed to reach statistical significance in patients with multiple system atrophy (MSA), although the company says there are encouraging “signals of efficacy” in the data.

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Clues from mice could help explain why women face a higher risk of autoimmune disorders

STAT

Researchers have long known that women are more likely to develop autoimmune disorders than men, though they’ve struggled to fully understand why. Now a new study in mice suggests a key part of the answer may be that an RNA molecule that’s indispensable for female survival steers the body toward immune friendly fire. A team led by Stanford scientists found that Xist, a molecule that teams up with proteins to keep female cells from activating a double (and deadly) dose of X chromoso

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Ron Lanton, Partner, Lanton Law PLLC, Discusses New Drug Plus Pricing Models

Pharmaceutical Commerce

In an interview with Pharma Commerce Associate Editor Don Tracy, Ron Lanton, Partner, Lanton Law PLLC, discusses recent moves by CVS and Express Scripts to follow Mark Cuban's drug plus model.

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5 Reasons to Upgrade Your Pharmacy Management Software

Are you still using workarounds to manage your daily operations? To achieve peak performance, it's time to explore other options for specialty and infusion pharmacy software. Streamline pharmacy operations and improve clinical performance with automated processing, real-time data exchange, and electronic decision support. Download this helpful infographic to: Drive efficiency and patient adherence from referral receipt to delivery and ongoing care – all with our Pharmacy Cloud.

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Cour gets $105M, pharma help to ‘reprogram’ autoimmune disease

BioPharma Dive

Roche, Pfizer and Bristol Myers Squibb have all invested in the startup, which is using nanoparticle technology to retrain the body’s immune system.

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Digital prescriptions added to NHS App

pharmaphorum

From today, a new feature added to the NHS App used in the UK will allow millions of people to submit and view prescriptions, in a bid to save time for patients and doctors. The digital prescription function, which does away with the need for paper scrip, was put through its paces in a pilot trial last year involving a million users of the app, now being used by three-quarters of the UK population or around 33.5 million people.

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STAT+: Ultima Genomics launching high-end DNA sequencers that can read genome for $100

STAT

Ultima Genomics, an upstart some observers have called a “ dark horse ” in the world of DNA sequencing, will soon launch a line of high-power instruments that can read a human genome for as little as $100, the company’s leadership told STAT. The sequencer, dubbed the UG 100, is a $1.5 million machine that can read up to 20,000 human genomes a year.

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Industry lauds Union Budget’s focus on Women’s Health

Express Pharma

Overall, the Union Budget 2024 reflects a forward-looking approach OPPI commends the Government’s approach towards the healthcare and pharmaceutical sector in the Union Budget 2024. The emphasis on leveraging existing hospital infrastructure for establishing new medical colleges is a strategic move that aligns with the need for a robust healthcare workforce.

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Roche shuffles early stage pipeline as it joins obesity rush

BioPharma Dive

Roche said it was shelving those drugs in favor of experimental programs to treat obesity that it gained from its takeover of Carmot Therapeutics.

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