Sat.Sep 14, 2024 - Fri.Sep 20, 2024

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Second health care worker tied to Missouri bird flu case had respiratory symptoms

STAT

A second health worker who cared for a person hospitalized in Missouri with H5N1 bird flu developed mild respiratory symptoms but was not tested for influenza, the Centers for Disease Control and Prevention reported on Friday. The CDC said Missouri health officials didn’t learn that the health worker had symptoms until after the individual had recovered, too late to run a diagnostic test.

Hospitals 364
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SAEM Clinical Images Series: Below the Chin, Badness Lies Within

ALiEM - Pharm Pearls

A 50-year-old male with insulin-dependent Type 2 Diabetes presented to the emergency department with three days of pain and swelling on the right side of his neck. He endorsed progression of his symptoms, reporting that he was now having fevers, myalgias, and intermittent difficulty swallowing solid foods. Additional Images Physical Exam Vitals : BP 153/96; HR 110; T 100.0°F; RR 16; O2 sat 97% General : Appears uncomfortable HEENT : Mild right-sided facial swelling.

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Agility in action: 5 ways to fast-track your clinical trial

PharmaVoice

Five ways to beat study timeline pressures and get medicines to patients faster.

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Vizient announces 2024 top performers in clinical quality, supplier diversity and environmental sustainability excellence

vizient

The awards recognize the achievements of participating hospitals and health systems in patient care quality and supply chain excellence and were announced Sept. 17 in Las Vegas.

Hospitals 139
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Why Every Small Business Needs an HCM Solution: A Comprehensive Guide

Managing HR tasks like payroll, compliance, and employee data can overwhelm small businesses. That’s where a Human Capital Management (HCM) solution comes in. Our eBook, Why Every Small Business Needs an HCM Solution: A Comprehensive Guide , shows how an HCM system automates tedious processes, ensuring your business stays compliant and efficient. You’ll learn how to simplify payroll, eliminate costly errors, and empower your employees with self-service tools.

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STAT+: FTC sues big 3 PBMs for ‘artificially inflated’ insulin prices caused by ‘perverse’ rebating

STAT

The U.S. Federal Trade Commission filed a lawsuit against the largest pharmacy benefit managers and their group purchasing organizations for allegedly anticompetitive practices that “artificially inflated” the price of insulin and, consequently, impeded patient access to the life-saving treatment. The administrative complaint accused CVS Caremark, Cigna’s Express Scripts, and UnitedHealth’s OptumRx of creating a “perverse” system of rebates that favored

Diabetes 363
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2275 pharmacies have closed so far in 2024

Ramblings of a pharmacist

“It’s not the way I wanted it to go,” he says sadly. “You do what you’re supposed to do. You go to college, get a doctorate, start a small business in a small town, support the community and it’s not even close to being a viable option.” “This isn’t because the community didn’t support us. It’s because we lose money on every prescription we fill.” Those are the words of Tom Wullstein, owner of Brandon Pharmacy.

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Apellis eye drug again turned back in Europe

BioPharma Dive

The decision against Syfovre’s approval follows efforts by Apellis to have reviewers reevaluate clinical evidence multiple times and, according to an analyst, will lead to a restructuring of the company’s operations in Europe.

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FDA approves first at-home flu vaccine in U.S., a nasal spray

STAT

The Food and Drug Administration on Friday approved AstraZeneca’s bid to allow its nasal spray influenza vaccine, FluMist, to be sold for home administration.  Starting next flu season, people who want to order the vaccine to give it to themselves or their children at home will be able to do so.

Vaccines 363
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GPhC proposes stricter guidance for online pharmacies and weight loss meds

The Pharmacist

The General Pharmaceutical Council (GPhC) has proposed new guidance to safeguard against the risks of online prescribing, including of weight loss medication. This follows 'significant risks to patient safety when online questionnaires have inappropriately been the only mode of consultation used', which the GPhC said it had observed through its inspections and investigations.

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Getting IND ready — how companies can avoid common traps

PharmaVoice

Overpromising, overcommitting and neglecting CMC are a few of the pitfalls that cause sponsors to stumble when submitting a new drug application.

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From Payroll Pains to Growth Gains: Streamlining Payroll & HR for Success

Speaker: Joe Sharpe and James Carlson

In the world of small business management, the challenge of managing payroll & HR efficiently while scaling operations can be overwhelming. Yet, with the right strategies in place, these challenges can become opportunities for growth and innovation. In this session, Joe Sharpe, Senior Director of Managed Payroll Services at IRIS, will reveal practical methods and expert insights for outsourcing and streamlining payroll processes, resulting in substantial time and resource savings.

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Ascendis trial data piles pressure on BioMarin

BioPharma Dive

Summary study results show Ascendis’ drug for achondroplasia could be competitive to BioMarin's Voxzogo, which is the foundation of the latter company's growth plans.

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Long-overlooked scientist shares Lasker Award with other GLP-1 researchers

STAT

GLP-1 based drugs are transforming the treatment of obesity and opening up new avenues for addressing heart disease , addiction , and even Alzheimer’s. Now, three scientists who played key roles in their invention have won a prestigious Lasker Award for biomedical research.  Announced on Thursday in New York, the Lasker-DeBakey Clinical Medical Research Award will be shared by Svetlana Mojsov and Joel Habener , who identified and characterized the GLP-1 hormone in the 1980s whil

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Negotiator 'interested' to hear outcome of NPA ballot

The Pharmacist

Community Pharmacy England (CPE) has suggested that the outcome of the National Pharmacy Association (NPA)'s ballot could inform considerations around its own negotiating tactics and positioning. Pharmacy sector leaders have today joined the NPA to deliver a petition to Downing Street and to voice concerns about pharmacy funding, following the membership organisation's announcement that it […] The post Negotiator 'interested' to hear outcome of NPA ballot appeared first on The Ph

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FDA inspection backlog overseas threatens new drug approvals

PharmaVoice

The FDA’s backlog of overseas drug manufacturer inspections is still mounting — and new drugs could be delayed as a result.

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Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

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Ten-year survival data show long-term benefit of immunotherapy in melanoma

BioPharma Dive

Final follow-up results suggest Opdivo and Yervoy could be close to a cure for some people with advanced melanoma, shifting how doctors administer follow-up care.

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Year-long fallout over retracted trans youth paper highlights new research era

STAT

Last year, a Springer Nature journal published a study surveying 1,700 parents of adolescents and young adults with gender dysphoria. Just a few months later, the study was retracted because there had been no formal process for those parents to consent to the study. But the story didn’t end there. Ongoing fallout from the paper and its retraction has opened up an internal rift among academic editors and journal staff that led to one editor’s resignation, as first reported by Retrac

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Top three trends in precision medicine

Pharmaceutical Technology

An innovative approach to healthcare, precision medicine is a new medical model that takes into account individual differences in genes, environments, and lifestyles to drive better outcomes through medicine.

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How a radiopharma up-and-comer builds momentum in a surging space

PharmaVoice

Big Pharma is embracing the radiopharmaceuticals boom that was a long time in the making.

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Enhance Healthcare Efficiency With Top Payroll & HCM Services

Running a healthcare facility requires precision and care, not just for patients but also for your staff. Our guide, "A Buyer’s Guide to Payroll & HCM Services," helps healthcare providers choose the best provider. Efficient payroll management ensures timely, accurate payments, critical for maintaining staff morale and trust. Compliance support helps navigate complex healthcare regulations and avoid costly fines.

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How to Develop a Competitive Generic Drug Portfolio

Drug Patent Watch

The generic drug market in the United States is characterized by significant price volatility and shortages, driven by the structure of the market and the incentives for manufacturers. To address these issues, several market-based proposals have been put forth to optimize generic drug cost and availability.

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Opinion: Tested in Africa, used in America

STAT

At the recent annual International AIDS Conference, a startling presentation about the newest wonder drug in HIV prevention brought a raucous standing ovation. Lenacapavir, a novel drug given as an injection under the skin every six months, was 100% successful in preventing HIV in adolescent girls and young women in two countries in Africa. It felt to many like a generational moment.

Vaccines 353
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PBM strikes back at FTC over drug pricing report

pharmaphorum

PBM Express Scripts has sued the FTC, claiming its recent report on the sector's role in drug pricing is defamatory and should be retracted

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Nura Bio gets another $68M, new CEO to advance ‘neuroprotective’ brain drugs

BioPharma Dive

The funding will support mid-stage testing of a drug the company believes to have the potential to treat a range of neurodegenerative conditions.

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5 Reasons to Upgrade Your Pharmacy Management Software

Are you still using workarounds to manage your daily operations? To achieve peak performance, it's time to explore other options for specialty and infusion pharmacy software. Streamline pharmacy operations and improve clinical performance with automated processing, real-time data exchange, and electronic decision support. Download this helpful infographic to: Drive efficiency and patient adherence from referral receipt to delivery and ongoing care – all with our Pharmacy Cloud.

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Novavax announces availability of Covid-19 vaccine in US pharmacies

Pharmaceutical Business Review

This vaccine is intended for individuals aged 12 and above and is now stocked at pharmacies including CVS Pharmacy, Walgreens, Rite Aid among others. The vaccine has been granted Emergency Use Authorization by the US Food and Drug Administration on 30 August 2024. This authorisation allows for the distribution of Novavax’s updated vaccine, which is the only protein-based option available in the country for the upcoming fall season.

Vaccines 111
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STAT+: Ginkgo Bioworks bets on protein AI model, and data generation to turn flailing company around

STAT

Amid layoffs and a disintegrating share price, former investor darling Ginkgo Bioworks is trying out a new tack to find customers. The biotech this week announced a new artificial intelligence model for use in biological research, as well as a data service academic researchers and companies can use to develop their own models. The announcement comes as a growing number of biotechs, big tech companies, and academics apply neural networks and machine learning to biology, promising that the same ba

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Roundtable: Six months of Pharmacy First

The Pharmacist

Joanna Robertson reports on an exclusive roundtable, held in August this year, which brought together community pharmacy and general practice representatives to discuss the successes, challenges and future of Pharmacy First, six months after the service began in England. Pharmacy First launched in England on 31 January 2024, and sees pharmacists funded to provide advice […] The post Roundtable: Six months of Pharmacy First appeared first on The Pharmacist.

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Cutting Costs with a CDMO: Strategies for Success in Biopharmaceutical Manufacturing

Drug Patent Watch

The biopharmaceutical industry is constantly evolving, with the demand for complex biologics on the rise. To stay competitive, companies must navigate the complexities of biopharmaceutical development while managing costs effectively. One key strategy for achieving this balance is partnering with Contract Development and Manufacturing Organizations (CDMOs).

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F2G raises $100 million to combat innovation 'paucity in antifungals

Outsourcing Pharma

One year after a rejection by the US Food and Drug Administration (FDA), the UK firm F2G has raised $100 million to push its candidate olorofim to the market for the treatment of rare fungal infections in 2026.

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Q&A: The U.S. can, and should, do more on H5N1 bird flu, a top WHO official says

STAT

More work needs to be done by the agricultural sector to get to the bottom of — and put a stop to — transmission of H5N1 bird flu in dairy cattle in the United States, a senior World Health Organization official said over the weekend. Maria Van Kerkhove, the WHO’s acting director of epidemic and pandemic preparedness and prevention, said the world is watching how the U.S., with its advanced scientific expertise, is responding to this outbreak.

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ESMO 2024 – Today’s oncological roots are branching

pharmaphorum

ESMO 2024 began on Friday 13th September. Prof Andres Cervantes discussed how building trust has been a several generation development, following five decades of effort in the oncological space.

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ADC developed by Daiichi, Merck outperforms chemo in lung cancer trial

BioPharma Dive

The FDA previously rejected patritumab deruxtecan over manufacturing issues. Tuesday's study data should boost the companies' case, however.

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Protest action hoped to spotlight pharmacy plight

The Pharmacist

National Pharmacy Association (NPA) members across the UK have participated in a second day of action today by wearing black, displaying posters and raising awareness of the impact of funding cuts on the sector. It comes as the NPA has announced plans to escalate its action and ballot its members on 'working to rule'. Gordons […] The post Protest action hoped to spotlight pharmacy plight appeared first on The Pharmacist.

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STAT+: Express Scripts sues FTC over a ‘biased’ report about pharmacy benefit managers

STAT

Express Scripts, one of the largest pharmacy benefit managers in the U.S., filed a lawsuit on Tuesday demanding that a recent Federal Trade Commission report accusing industry middlemen of raising drug prices be vacated. In scathing language, the company argued the report was “seventy-four pages of unsupported innuendo leveled … under a false and defamatory headline.