Sat.Aug 05, 2023 - Fri.Aug 11, 2023

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What pharma companies are getting wrong about drug repositioning

PharmaVoice

Children’s Tumor Foundation president Annette Bakker is working to teach the industry the crucial difference between drug repurposing and drug repositioning.

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Kim Kardashian sparks debate on the benefits of full-body MRI scans

STAT

The last time Kim Kardashian posted about medical imaging, it was to prove her butt was real. Now, she’s praising its ability to find aneurysms and cancers before they turn deadly. Kardashian’s Instagram post this week about Prenuvo, which sells full-body MRI scans that can run in the thousands of dollars, has renewed a long-running debate about whether the tests are actually valuable or just run the risk of clogging hospitals with false positives and unnecessary follow-ups from we

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PEM POCUS Series: Pediatric Lung Ultrasound

ALiEM - Pharm Pearls

Read this tutorial on the use of point of care ultrasonography (POCUS) for pediatric lung ultrasound. Then test your skills on the ALiEMU course page to receive your PEM POCUS badge worth 2 hours of ALiEMU course credit. Take the ALiEMU PEM POCUS: Pediatric Lung Ultrasound Quiz Module Goals List indications for performing a pediatric lung point-of-care ultrasound (POCUS).

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HIV cell therapy startup Addimmune heads to Wall Street via blank-check merger

BioPharma Dive

The deal will help fund a cell-based treatment that completed Phase 1 testing last year and is designed to provide a “functional cure” for patients with HIV infections.

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From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

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In the era of blockbuster obesity drugs, a personalized approach could boost outcomes

PharmaVoice

Ozempic and Wegovy have become household names for weight loss. But obesity is complex, and Phenomix Sciences is looking to bring a personalized medicine approach to the field.

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Bird flu researchers turn to Finland’s mink farms, tracking a virus with pandemic potential

STAT

HELSINKI — It was the quiet that stood out to Tarja Sironen at the fur farm. A specialist in emerging infectious diseases, Sironen has conducted research at fur farms for years. She helped develop a Covid vaccine that was deployed to the country’s mink population during the pandemic. She knows the industry well.

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More Trending

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How To Get Accurate Lab Tests When Taking Thyroid Medications

The Thyroid Pharmacist

Thyroid hormones are “Goldilocks” hormones: the dose has to be “just right” for us to feel optimal. Doses that are too high or too low can result in symptoms. I get tons of messages from people who report that they had begun to feel hypothyroid symptoms after having their thyroid medications reduced, based on a faulty lab interpretation. One lady began to lose her hair in clumps; another became nearly bedridden!

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Pharma’s rocky love affair with oxytocin

PharmaVoice

Although research on using oxytocin as a drug has varied, Tonix Pharmaceuticals is banking on the “love hormone” to treat autism, anxiety and more.

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STAT+: Telehealth companies are driving a large share of weight loss drug prescriptions, claims data suggest

STAT

As a new class of obesity medications has soared in popularity, so have the online outlets built to get them in the hands of patients. A new analysis of claims data from Trilliant Health suggests that collectively, telehealth companies — in particular, cash-pay options that market directly to consumers — could account for nearly half of the patients with insurance claims for GLP-1 prescriptions in 2022.

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Bridging the Divide: Medical's Omnichannel Momentum

PharmExec

How pharma medical affairs and commercial teams are synchronizing their capabilities to boost omnichannel marketing strategies and better understand customer engagement needs.

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Why Every Small Business Needs an HCM Solution: A Comprehensive Guide

Managing HR tasks like payroll, compliance, and employee data can overwhelm small businesses. That’s where a Human Capital Management (HCM) solution comes in. Our eBook, Why Every Small Business Needs an HCM Solution: A Comprehensive Guide , shows how an HCM system automates tedious processes, ensuring your business stays compliant and efficient. You’ll learn how to simplify payroll, eliminate costly errors, and empower your employees with self-service tools.

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Your Next Leadership Step – Stay Put!

The Honest Apothecary

Have you ever asked yourself this question: “What is the next step in my leadership journey?” It is a good question. Leadership is like climbing a mountain that has no pea or a ladder that has no top rung. Real leaders are generally hungry for the next challenge. They take a tough opportunity, give it their best, then start looking for the next giant to go after.

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A pioneering approach to biotherapeutic antibody discovery

PharmaVoice

Immunotherapy has revolutionized cancer treatment, yet the drug discovery process to develop new biotherapeutic antibodies remains arduous.

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STAT+: Anavex, maker of rare disease drug, keeps shifting the goalposts in its clinical trials

STAT

Anavex Life Sciences is in a tough spot. The serial dissembler of clinical trial results might be forced, finally, to tell the truth when it reads out its next study in Rett syndrome. What sets Anavex apart from all the other biotechs on my radar screen is its habit of shifting the goalposts on clinical trials. Twice last year, first in February and then in December , Anavex announced “positive” outcomes from studies of its drug called blarcamesine — except the results were

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A Fierce Focus On Unmet Need

PharmExec

From public defender to spearheading the adoption of innovative drugs, Wendy Short Bartie, senior VP and general manager for the hematology and cell therapy division at Bristol Myers Squibb, has remained a steadfast patient advocate—working to fulfill unmet medical needs and bring treatments to as many people as possible.

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Best Practices to Streamline Compensation Management: A Foundation for Growth

Speaker: Joe Sharpe and James Carlson

Payroll optimization can be one of the most time-consuming and complex factors of small business management. Yet, organizations that crack the code on streamlining employee compensation often discover innovative avenues for growth. With the right strategies in place, outsourcing and streamlining payroll processes can result in substantial time and resource savings.

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J&J grows cancer drug portfolio with newly approved bispecific

BioPharma Dive

The drug, which will be sold under the brand name Talvey, is now cleared by the FDA to treat multiple myeloma, a blood cancer that J&J has identified as a research priority.

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Antibiotic Interactions: Combinations to Avoid for Safe Medication

FADIC

Antibiotic Interactions: Avoid for Safe Medication Antibiotic Interactions: Combinations to Avoid for Safe Medication 🧵Some combinations of antibiotics and non-antibiotics that should be avoided💊🚫 1. Flucloxacillin β-lactams are considered to be less prone to drug interactions. Flucloxacillin, however, may ⬇️ tacrolimus concentration, presumably through enzyme induction The same can occur with flucloxacillin and broad-spectrum azoles (vori/posa) LINK 2

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Study mapping how SARS-CoV-2 disrupts mitochondria suggests a cause for long Covid

STAT

In yet another example of Covid’s seemingly limitless reach into our bodies, new research maps out how the SARS-CoV-2 virus disrupts mitochondria, the power plants in all our cells. The extent of the damage, spanning the lungs, heart, liver, kidneys, and brain, could potentially be one explanation for the lengthy list of persistent symptoms of long Covid , from fatigue to brain fog.

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Top Ten Tips for Taking the NBSTSA Surgical Technology Exam

Board Vitals - Pharmacist

The journey to becoming a certified surgical technologist is a noble one, filled with dedication, perseverance, and a commitment to excellence. At the heart of this journey lies a crucial milestone – the NBSTSA Surgical Technology Exam. This comprehensive exam contains 175 questions (150 graded) with a pass rate of just 73.7% in 2020. How can you best prepare for the CST exam ?

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Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

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Multiple myeloma bispecific antibody granted accelerated approval

European Pharmaceutical Review

The US Food and Drug Administration (FDA) has granted accelerated approval of TALVEY (talquetamab-tgvs) to treat multiple myeloma. Janssen Pharmaceutical Companies of Johnson & Johnson’s first-in-class bispecific T-cell engaging antibody showed an overall response rate (ORR) of over 70 percent in heavily pre-treated multiple myeloma. Based on this data, TALVEY is indicated for adults with relapsed or refractory multiple myeloma who have received at least four prior lines of therapy, includin

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GLP-1 Agonists and Gastroparesis

Med Ed 101

There’s always this voice in the back of my head that always cautions me that all that glitters is not gold. After being heralded as the next savior in weight loss by the media, the GLP-1 Agonists/GIP agonists have come under more scrutiny lately in the news. A recent article on CNN details patients who […] The post GLP-1 Agonists and Gastroparesis appeared first on Med Ed 101.

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‘Underwhelming’: NIH trials fail to test meaningful long Covid treatments — after 2.5 years and $1 billion

STAT

More than 2.5 years after the National Institutes of Health received a $1 billion mandate from Congress to study and treat long Covid , the agency has finally launched clinical trials for the often-debilitating condition. But both scientists who study long Covid and patients who have struggled with it say the trials are unlikely to deliver meaningful treatments, suggesting the federal government’s landmark Covid research effort may have been wasted.

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Q&A: Dr. Daniel Hernandez, Director of Medical Affairs and Hispanic Outreach, Global Healthy Living Foundation

PharmExec

Hernandez details how the non-profit organization advocates for improved access to care at the community, state, and federal levels, and amplifies education and awareness efforts within its social media communities.

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Enhance Healthcare Efficiency With Top Payroll & HCM Services

Running a healthcare facility requires precision and care, not just for patients but also for your staff. Our guide, "A Buyer’s Guide to Payroll & HCM Services," helps healthcare providers choose the best provider. Efficient payroll management ensures timely, accurate payments, critical for maintaining staff morale and trust. Compliance support helps navigate complex healthcare regulations and avoid costly fines.

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ADC oncology therapy market to value over $36b by 2029

European Pharmaceutical Review

According to research from GlobalData, the pharmaceutical industry is shifting towards development of antibody-drug conjugates (ADC) as oncology treatments. The data showed that Daiichi Sankyo , Seagen and Roche are currently three of the most important companies in the ADC market. Daiichi Sankyo was predicted to remain the dominant player in this market.

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Emergent to lay off around 400 in pivot away from contract manufacturing

BioPharma Dive

The job cuts will affect “all areas of the company” and, combined with other cost-reduction efforts, lead to annualized savings of over $100 million, Emergent said.

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Study shows autistic people are more likely to engage in self-harm — but not because of autism

STAT

Autistic people are at a much higher risk of self-harm leading to emergency care or suicide, according to a recent study published in JAMA Network Open. In particular, the study found, autistic females had an 83% increased risk of self-harm compared to non-autistic females, while for males, the increased risk compared to non-autistic individuals was 47%.

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Embracing Programmatic Advertising to Enhance Targeting of HCPs

PharmExec

The precision of programmatic advertising is reshaping the way life sciences brands engage with healthcare professionals, offering enhanced personalization, scale, and optimization in today's digital landscape.

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5 Reasons to Upgrade Your Pharmacy Management Software

Are you still using workarounds to manage your daily operations? To achieve peak performance, it's time to explore other options for specialty and infusion pharmacy software. Streamline pharmacy operations and improve clinical performance with automated processing, real-time data exchange, and electronic decision support. Download this helpful infographic to: Drive efficiency and patient adherence from referral receipt to delivery and ongoing care – all with our Pharmacy Cloud.

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European Commission revokes marketing authorisation for Novartis’ crizanlizumab

European Pharmaceutical Review

The European Commission has revoked the conditional marketing authorisation (MA) for Novartis’ sickle cell medicine crizanlizumab in the European Union (EU) and EEA. The decision follows a May recommendation from the European Medicine Agency’s Committee for Medicinal Products for Human Use (CHMP). Crizanlizumab is a once-a-month, humanised monoclonal antibody infusion, indicated for the prevention of recurrent vaso‑occlusive crises (pain crises) in sickle cell disease patients aged 16 yea

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Lilly market value soars on higher sales, obesity drug potential

BioPharma Dive

The Indianapolis drugmaker is now worth more than $500 billion, higher than any other pharmaceutical company, as analysts project lucrative markets for its obesity and Alzheimer's drugs.

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Senators push IRS to launch nonprofit hospital probe

STAT

WASHINGTON — A bipartisan group of senators wants federal tax regulators to probe nonprofit hospitals’ compliance with community benefit requirements, ratcheting up a longtime campaign to hold the tax-exempt providers accountable. Nonprofit hospitals are often subsidized by state or federal funding and exempt from many taxes. In exchange, they are required to aid their surrounding area through public health programs and providing free or discounted care to low-income patients.

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AI and Drug 'Re-Innovation'

PharmExec

The application of artificial intelligence is steadily finding a home in the pharma industry, but these tools may have unprecedented potential in a more nascent niche along the life sciences continuum: drug development.

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Semaglutide demonstrates cardiovascular benefit

European Pharmaceutical Review

Headline results from Novo Nordisk’s “landmark” SELECT trial in cardiovascular outcomes has demonstrated a 20 percent reduction in major adverse cardiovascular events (MACEs) for semaglutide 2.4mg (Wegovy ® ) compared to a placebo. “People living with obesity have an increased risk of cardiovascular disease but to date, there are no approved weight management medications proven to deliver effective weight management while also reducing the risk of heart attack, stroke or cardio