Sat.May 25, 2024 - Fri.May 31, 2024

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NIH documents show how $1.6 billion long Covid initiative has failed so far to meet its goals

STAT

More than three years ago, the National Institutes of Health launched a $1 billion-plus initiative to find the root causes and potential treatments for long Covid , the chronic disease that has quickly changed the lives of millions of Americans. But a lack of visible progress from the initiative, called RECOVER, has drawn months of criticism from patient advocates, researchers, and lawmakers, including at a Senate hearing last week on the NIH’s budget.

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As Senate’s gaze lands on patents, a former US PTO chief calls the effort a ‘broad misunderstanding’

PharmaVoice

To lower drug prices, lawmakers are turning to the drug patent system to outlaw some common practices — but a former patent agency director says it’s the wrong way to go.

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Interview: Has Cybin hit the biggest breakthrough in 40 years to treat psychiatric disorders?

Outsourcing Pharma

In an intriguing interview with Cybinâs CEO, Doug Drysdale, OSP senior editor, Liza Laws found out how second-generation psychedelics could be the biggest breakthrough in psychiatry in 40 years.

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COVID-19 vaccinations now ‘alarmingly low’ in Europe

pharmaphorum

COVID-19 vaccination rates have fallen precipitously in Europe and should be ramped up this autumn so they are at least in line with influenza vaccine uptake.

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From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

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A third U.S. farm worker infected with bird flu is the first to experience respiratory symptoms

STAT

A third human case of H5 bird flu tied to the ongoing U.S. outbreak in cattle has been detected in a farm worker in Michigan, state health authorities confirmed on Thursday. The unnamed individual worked on a dairy farm and was in close contact with infected cows, the state health department said in a statement. The farm involved is different from the one where an earlier human case was detected last week.

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Can robots break the cell therapy bottleneck?

PharmaVoice

A partnership between the cell therapy delivery specialist Portal Biotechnologies and precision robotics maker Multiply Labs could bring the manufacturing bottleneck under control, the CEOs said.

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More Trending

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Short reads, big impact: How genomics is revolutionising cancer research

pharmaphorum

Discover how genomics is transforming cancer research through the study of DNA, RNA, and ctDNA. Learn about the latest breakthroughs in the field in this insightful short read.

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The new menstruation: Girls are getting their periods earlier and less regularly

STAT

Menstruation is a critical indicator of health. Whether and when someone with a uterus gets their period — for the first time, and throughout their life — can reflect not only their reproductive health, but their risk of cardiovascular disease, cancer, miscarriage, and premature death. That also makes menstruation a useful measure of population health.

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As weight loss booms, drugmakers look for an edge with oral options

PharmaVoice

Supply of GLP-1 medications falls well short of demand, and oral versions of the drugs loom over Eli Lilly and Novo Nordisk’s dominance.

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From Healing to Harm: The Unintended Consequences of Polypharmacy in Seniors

PharmD Live

Polypharmacy, or the concurrent use of at least five medications, can be essential for individuals with multiple chronic conditions. When medications are prescribed with clear therapeutic objectives, optimized to minimize adverse drug reactions (ADRs), and the patient adheres to the regimen, polypharmacy can be appropriate and beneficial. However, it often becomes excessive and hazardous when medications are unnecessary, fail to meet therapeutic goals, pose a high risk of ADRs, or when the patie

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Why Every Small Business Needs an HCM Solution: A Comprehensive Guide

Managing HR tasks like payroll, compliance, and employee data can overwhelm small businesses. That’s where a Human Capital Management (HCM) solution comes in. Our eBook, Why Every Small Business Needs an HCM Solution: A Comprehensive Guide , shows how an HCM system automates tedious processes, ensuring your business stays compliant and efficient. You’ll learn how to simplify payroll, eliminate costly errors, and empower your employees with self-service tools.

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AZ’s Dato-DXd misses survival endpoint in lung cancer trial

pharmaphorum

The overall survival (OS) data has come in from the TROPION-Lung01 study of AstraZeneca and Daiichi Sankyo’s datopotamab deruxtecan (Dato-DXd) in lung cancer – and the result likely isn’t what they were hoping for.

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Opinion: The world needs the new pandemic treaty

STAT

At the height of the Covid-19 pandemic, 25 heads of government issued an extraordinary call for a new international treaty for preventing, preparing for, and responding to pandemics. For two years, World Health Organization member states have been negotiating an international agreement scheduled for adoption at the World Health Assembly this month. Yet, late Friday in Geneva, negotiations ground to a halt.

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FTC request may signal trouble for Novo/Catalent deal

PharmaVoice

As Novo Nordisk aims to secure its manufacturing foothold for GLP-1s, regulators are digging for clues of anti-competitive behavior.

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Improving stem cell transplantation success in high-risk blood cancers

European Pharmaceutical Review

Repurposing cyclophosphamide may enable more patients with high-risk blood cancers to receive transplanted stem cells from unrelated, partially matched donors, new research suggests. These new findings, which are part of an ongoing Phase II study , will be presented at the 2024 American Society of Clinical Oncology (ASCO) meeting and the European Hematology Association ( Abstract #6503 ).

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Best Practices to Streamline Compensation Management: A Foundation for Growth

Speaker: Joe Sharpe and James Carlson

Payroll optimization can be one of the most time-consuming and complex factors of small business management. Yet, organizations that crack the code on streamlining employee compensation often discover innovative avenues for growth. With the right strategies in place, outsourcing and streamlining payroll processes can result in substantial time and resource savings.

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US Congress passes bill to end Parkinson’s disease

pharmaphorum

The US Congress has passed the first-ever federal bill dedicated to ending Parkinson’s disease, modelled on similar legislation for Alzheimer’s enacted in 2011

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STAT+: Gene therapies for deafness dredge up an old question: Do deaf people want a ‘cure’?

STAT

When Yilai Shu was training to be an otolaryngologist in Shanghai, in the mid 2000s, he often met parents with congenitally deaf kids. “They always asked me, ‘Do you have any drugs to treat our kids?’ said Shu, who is hearing and a professor at Fudan University in China. “That’s what really inspired me to think about developing a drug.

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Can robots break the cell therapy bottleneck?

BioPharma Dive

A partnership between cell therapy delivery specialist Portal Biotechnologies and precision robotics maker Multiply Labs could address manufacturing hurdles, the CEOs said.

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Major manufacturing investment to support API production for tirzepatide

European Pharmaceutical Review

A new $5.3 billion investment for Eli Lilly and Company ’s manufacturing site in Lebanon, Indiana, US, increases the firm’s total investment there from $3.7 billion to $9 billion. This expansion will expand manufacturing capacity of active pharmaceutical ingredients (APIs) for Zepbound ® (tirzepatide) injection and Mounjaro ® (tirzepatide) injection.

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Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

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Working for a mature form of genomic medicines

pharmaphorum

In a new episode of the pharmaphorum podcast, Rahul Kakkar, CEO of gene editing company Tome, speaks with web editor Nicole Raleigh about programmable genomic integration (PGI) technology.

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At Las Vegas conference, methadone clinics blast idea of doctors prescribing directly

STAT

LAS VEGAS — Mark Parrino, the longtime leader of the U.S. methadone clinic industry, kicked off his organization’s conference here last week with a simple message: Allowing addiction doctors to prescribe the medication directly to their patients is “not a good idea.”  It was a revealing warning both in timing and tone.

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Neurology remains key therapeutic area for Japan pharma majors: GlobalData

Express Pharma

In the dynamic landscape of healthcare, key neurological disorders like Alzheimer’s disease, epilepsy, Parkinson’s disease, and depression pose significant challenges, particularly in the Asia-Pacific (APAC) region, where prevalence is high. The World Health Organization stated in March 2024 that “over 80 per cent of neurological deaths and health losses occur in low- and middle-income countries, and access to treatment varies widely.

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Lignin-based drug delivery system may improve chemotherapeutics

European Pharmaceutical Review

Researchers have defined the conditions to formulate novel polyelectrolyte complexes (PECs) based on a sustainable hemicellulose-rich lignosulphonate. Their findings suggest potential applications in drug delivery. Novel biomaterials based on PECs are being investigated in the industry as drug delivery systems, due to PECs being able to “to entrap drugs under mild conditions and control their release”.

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Enhance Healthcare Efficiency With Top Payroll & HCM Services

Running a healthcare facility requires precision and care, not just for patients but also for your staff. Our guide, "A Buyer’s Guide to Payroll & HCM Services," helps healthcare providers choose the best provider. Efficient payroll management ensures timely, accurate payments, critical for maintaining staff morale and trust. Compliance support helps navigate complex healthcare regulations and avoid costly fines.

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Digital therapeutics firm Akili agrees $34 million takeover

pharmaphorum

More consolidation in the digital health sector as Akili agrees a $34m takeover by Virtual Therapeutics, returning to private hands.

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Opinion: Stigma and the return of syphilis

STAT

Syphilis, one of the oldest infections known to humans, has returned to the U.S. at epidemic rates that have been climbing since 2001. In 2022, the last year with complete data, the highest number of infections were recorded in more than 70 years. It’s not yet clear why syphilis is spreading faster than other sexually transmitted infections. Recent shortages of single injection penicillin needed to treat this infection threatens to make matters worse.

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Drug shortage in the US to prove beneficial for Indian pharma companies

Express Pharma

India Ratings and Research (Ind-Ra) expects US-focused pharma companies to sustain their revenue improvement trend in FY25 on account of heightened drug shortages in the US market. This will not only provide potential for volume growth, but also limit price erosion to single digits over the next 12-18 months, leading to improved returns. Also, given the limited original abbreviated new drug application (ANDA) filings and delays in approvals provided by the USFDA, the drug shortage in the US prov

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GP referrals 'key' to Pharmacy First success, analysis suggests

The Pharmacist

Referrals from GP practices and NHS services are ‘key’ to the success of Pharmacy First, the Company Chemists' Association (CCA) has suggested, following its analysis of Pharmacy First consultations around the country. Latest analysis of the number of Pharmacy First consultations in CCA pharmacies across England has suggested disparity between the success of the service […] The post GP referrals 'key' to Pharmacy First success, analysis suggests appeared first on The Pharmacist.

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5 Reasons to Upgrade Your Pharmacy Management Software

Are you still using workarounds to manage your daily operations? To achieve peak performance, it's time to explore other options for specialty and infusion pharmacy software. Streamline pharmacy operations and improve clinical performance with automated processing, real-time data exchange, and electronic decision support. Download this helpful infographic to: Drive efficiency and patient adherence from referral receipt to delivery and ongoing care – all with our Pharmacy Cloud.

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ASCO: Novartis’ Scemblix aces first-line CML study

pharmaphorum

Novartis’ Scemblix could be headed for first-line use in chronic myeloid leukaemia after outperforming TKI drugs in the ASC4FIRST study presented at ASCO.

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STAT+: For one rare type of lung cancer, Pfizer pill reduces progression by 81%

STAT

There are a lot of reasons why updated data on Pfizer’s Lorbrena, a treatment for non-small cell lung cancer, might not seem to be a big deal. The results are an update on the clinical trial that resulted in the Food and Drug Administration granting Lorbrena full approval in 2001, so in a sense they are not even that new. For Pfizer investors, Lorbrena isn’t that big a deal, either.

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UK-based company selling breakthrough cannabis-based medicines now supplying the US

Outsourcing Pharma

UK based Celadon Pharmaceuticals Plc, that specializes in the development, production, and sale of breakthrough cannabis-based medicines, announced that it has begun shipping to the US.

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Early spike in demand for insect bites advice, suggests NHSE

The Pharmacist

Visits to the NHS England (NHSE) insect bites and stings web page were three times higher in the first three weeks of this month than in the same time period last year, suggesting an early spike in interest, a deputy chief nursing officer (CNO) has said. According to NHSE, the page received a total of […] The post Early spike in demand for insect bites advice, suggests NHSE appeared first on The Pharmacist.

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AstraZeneca throws its hat into the oral PCSK9 ring

pharmaphorum

AstraZeneca has reported the first clinical data with its oral PCSK9 inhibitor AZD0780, which it hopes could offer an alternative to current injectable drugs used to lower cholesterol.

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