Sat.Dec 03, 2022 - Fri.Dec 09, 2022

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Opinion: If you think health care is dysfunctional now, just wait until after January 1

STAT

Doctors across the country, especially those in primary care, have been up in arms about Medicare’s proposed cuts in reimbursement that are scheduled to go into effect on January 1. They are concerned — rightfully so — that these cuts will be ruinous to their practices and compromise the care they can provide to their patients. As an emergency physician, I worry about the cuts for a different reason: emergency departments might soon be filled with more and more people who ca

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Woman of the Week: Simcha Therapeutics’ Beatrice McQueen

PharmaVoice

From sea sponges to cytokines, the chief operating officer’s career has come full circle as she pursues a new approach to treating cancer via the immune system.

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Kite and Daiichi Sankyo update cell therapy licensing agreement

Pharmaceutical Technology

Kite Pharma and Daiichi Sankyo have updated a partnership agreement signed in 2017 for the former’s CAR T-cell therapy, Yescarta (axicabtagene ciloleucel). Under the prior deal, Daiichi Sankyo acquired exclusive rights for the development, manufacturing and commercialisation of Yescarta in Japan. Subsequently, in the same year, Gilead Sciences acquired Kite.

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Investigation launched into alleged animal welfare violations at Neuralink

pharmaphorum

Elon Musk’s brain computer interface (BCI) company Neuralink is being investigated by law enforcement authorities in the US amid allegations of animal welfare violations in its testing facilities. Neuralink’s BCI is intended to treat conditions like blindness and spinal cord injury, as well as provide a way to interact with digital devices using the brain and, according to Musk, is on the brink of moving into the human testing stage.

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From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

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Opinion: Victims of domestic abuse should get the same top-notch concussion care as athletes

STAT

Two vastly different experiences — serving as a “guest coach” on the sidelines for a Division I football team and volunteering in a busy emergency department — showed me just how unequal and damaging the lack of care provided for women who are victims of domestic violence can be. In the first decade of the 2000s, one of the benefits of being a professor at Wake Forest University was the opportunity I received nearly every year to serve as a guest coach.

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For Duchenne-focused Sarepta, gene therapy is the natural next step

PharmaVoice

The company with three marketed RNA drugs for Duchenne muscular dystrophy is taking the logical leap into gene therapies with a candidate under review at the FDA.

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The promise of telomerase inhibitors for treating blood cancer

European Pharmaceutical Review

Geron’s CEO Chip Scarlett spoke to EPR to explain the science behind Imetelstat, the company’s leading telomerase inhibitor candidate. If successful, imetelstat could become the first-ever cancer treatment based on the inhibition of telomerase, helping to treat lower-risk myelodysplastic syndromes (LR MDS) , which leaves many patients dependent on blood transfusions.

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Opinion: Artificial intelligence: crossing the border between health care and tech

STAT

There’s been significant investment in companies creating artificial intelligence (AI) applications for health and health care over the last decade. But while there have been successes, notably in the area of medical imaging, the industry is known more for not yet living up to its potential — think IBM Watson. The slow pace of AI adoption in health care stems from the fact that health AI sits on the border between two large industries, health care and tech.

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A historic approval could transform CSL from being ‘the biggest company no one has ever heard of’

PharmaVoice

The company’s head of R&D on its profile-raising FDA approval of a gene therapy that’s now the world’s most expensive drug.

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WHO/PAHO launch free digital health assistant to cut alcohol-related diseases

pharmaphorum

A digital health assistant that can help people at risk of becoming dependent on alcohol has been launched in Belize, its first country, by the World Health Organisation (WHO) and Pan-American Health Organisation (PAHO). The artificial intelligence-powered assistant – called Pahola and available as a free online chat-based site – is designed to provide information and guidance to help people reduce their alcohol consumption, helping to prevent more than 200 health conditions linked to excessive

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Why Every Small Business Needs an HCM Solution: A Comprehensive Guide

Managing HR tasks like payroll, compliance, and employee data can overwhelm small businesses. That’s where a Human Capital Management (HCM) solution comes in. Our eBook, Why Every Small Business Needs an HCM Solution: A Comprehensive Guide , shows how an HCM system automates tedious processes, ensuring your business stays compliant and efficient. You’ll learn how to simplify payroll, eliminate costly errors, and empower your employees with self-service tools.

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Nkarta data supports natural killer cells in cancer treatment

Pharmafile

San Francisco, US-based Nkarta have been assessing the power of natural killer (NK) cells in oncology treatments. The treatment is as-yet unproven but appears hopefully at this early stage. Nkarta has just reported results from an early-stage trial of its CAR-NK therapies, which looks likely to generate enthusiasm to this area of research. read more.

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Cancer patients endure an overlooked financial burden: hospital parking fees

STAT

For many patients, one of the most antagonizing parts of a hospital visit is paying for parking. Those parking fees aren’t just an annoyance for the sick and injured, according to a new paper in the Journal of Medical Imaging and Radiation Sciences. The charges are actually eating into their financial well-being, particularly for people who have cancer and have to make frequent visits to the hospital for treatments like radiation and chemotherapy.

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Dr. Sy Pretorius, Eversana’s new COO, is flipping the script on his career

PharmaVoice

With a long history in the clinical space, Pretorius is now applying those deep insights to the commercial side of the business.

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Dostarlimab combination facilitates promising lung cancer survival

European Pharmaceutical Review

Phase II trial results from the largest global head-to-head trial of programmed death receptor (PD-1) inhibitors in patients with metastatic non-squamous non-small cell lung cancer ( NSCLC ), showed a median progression-free survival (mPFS) of 8.8 months for patients treated with Jemperli (dostarlimab) plus chemotherapy versus 6.7 months for those given pembrolizumab and chemotherapy.

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Best Practices to Streamline Compensation Management: A Foundation for Growth

Speaker: Joe Sharpe and James Carlson

Payroll optimization can be one of the most time-consuming and complex factors of small business management. Yet, organizations that crack the code on streamlining employee compensation often discover innovative avenues for growth. With the right strategies in place, outsourcing and streamlining payroll processes can result in substantial time and resource savings.

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Business and Passion

PharmExec

Kimberly Moran, head of rare diseases in the US for UCB, started off working in medicine but quickly learned the importance of the business side of industry—and its role in helping improve the diagnosis and access paths for underserved patient segments.

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Eli Lilly tightens access to diabetes drug, frustrating some people with obesity

STAT

Touted by celebrities, raved about by TikTok users and advertised by med spas, a new class of drugs for treating diabetes and obesity has exploded in popularity for its weight-loss effects, leading to rippling shortages across several of the medications. Amid the surge in demand, Eli Lilly and pharmacies have started to tighten access to the latest of this type of drug, tirzepatide, focusing on giving it to people with type 2 diabetes, the only population it’s authorized for so far.

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AI company zeros in on compounds to treat addiction by rewiring the brain

PharmaVoice

GATC Health is driving a novel approach it believes could work for several major neurological conditions.

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Health Canada approves Novavax’s Covid-19 vaccine for adolescents

Pharmaceutical Technology

Health Canada has granted approval for a supplement to a New Drug Submission (sNDS) of Novavax ’s Covid-19 vaccine (Recombinant protein, Adjuvanted), Nuvaxovid (NVX-CoV2373), for use in adolescents aged 12 to 17 years. The vaccine is indicated to be administered as a primary regimen comprising two doses for active immunisation to prevent Covid-19 in adolescents of this age group.

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Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

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Pluvicto™ offers survival benefits for metastatic prostate cancer

European Pharmaceutical Review

Novartis has announced its Phase III PSMAfore study with Pluvicto , lutetium (177Lu) vipivotide tetraxetan, demonstrated improved radiographic progression-free survival (rPFS) in patients with prostate-specific membrane antigen (PSMA)–positive metastatic castration-resistant prostate cancer (mCRPC) after androgen-receptor pathway inhibitor (ARPI) therapy, compared to a change in ARPI.

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Opinion: Deferral of primary care signals a troubled future for Americans’ health

STAT

Americans may be returning to their pre-pandemic habits , but most have not returned to their primary care doctors. Primary care visits are down 10.3% on average across U.S. cities relative to pre-pandemic levels. That, combined with more people with chronic diseases like diabetes, obesity, and cancer, and accelerating health care costs as inflation soars, signal a troubled future for the health of Americans and the U.S.

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10 noteworthy pharma leadership shake-ups this year

PharmaVoice

From GSK to Roche to Biogen, these were the most impactful executive changes at leading pharma companies in 2022.

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Elon Musk’s Neuralink brain interface chip set for human trials

pharmaphorum

Clinical trials of a wireless brain chip developed by Elon Muck’s Neuralink company will be tested in human volunteers within the next six months – and Musk himself says he intends to have one implanted for a future demo event. Neuralink has been promising that the technology will be ready for clinical trials soon for some time – first saying they were around the corner back in 2019 – so the latest announcement by Musk at an update last week may be met with some scepticism.

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Enhance Healthcare Efficiency With Top Payroll & HCM Services

Running a healthcare facility requires precision and care, not just for patients but also for your staff. Our guide, "A Buyer’s Guide to Payroll & HCM Services," helps healthcare providers choose the best provider. Efficient payroll management ensures timely, accurate payments, critical for maintaining staff morale and trust. Compliance support helps navigate complex healthcare regulations and avoid costly fines.

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What is Stiff-Person Syndrome? 

Board Vitals - Pharmacist

World-renowned singer, Celine Dion, recently announced on her Instagram the cancellation of tour dates due to her diagnosis of Stiff-Person Syndrome. What is Stiff-Person Syndrome (SPS), and how is it diagnosed and treated? . What is SPS? Stiff-Person Syndrome (SPS) is an extremely rare disease , affecting only one out of every million people. In fact, many neurologists will go their entire careers and only see one or two instances of the condition.

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Psychedelic therapy is moving to the next frontier: workplace perk

STAT

Acupuncture and chiropractic care weren’t always the common fixtures of employer benefit plans they are today. It took clamoring from workers, the accumulation of evidence, and the slow realization by businesses that those perks would be popular with workers. A similar evolution could be in store for psychedelic-assisted therapy for mental health conditions.

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Chasing a ‘holy grail’ cancer gene

PharmaVoice

Omega Therapeutics’ president and CEO Mahesh Karande on its attempts to drug the elusive c-Myc gene.

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Ex-Theranos exec Sunny Balwani gets 13 years for fraud

pharmaphorum

Ramesh “Sunny” Balwani, the former business partner of Theranos founder Elizabeth Holmes, has been sentenced to nearly 13 years in prison after being convicted of wire fraud. His sentencing comes after ex-Theranos chief executive Holmes was given more than 11 years in prison last month after also being found guilty of defrauding investors in Theranos, which said it had developed technology that could diagnose a host of diseases with just a few drops of blood taken with a finger prick, rather tha

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5 Reasons to Upgrade Your Pharmacy Management Software

Are you still using workarounds to manage your daily operations? To achieve peak performance, it's time to explore other options for specialty and infusion pharmacy software. Streamline pharmacy operations and improve clinical performance with automated processing, real-time data exchange, and electronic decision support. Download this helpful infographic to: Drive efficiency and patient adherence from referral receipt to delivery and ongoing care – all with our Pharmacy Cloud.

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Pharma and RWE: Hitting Its Stride

Pharmaceutical Commerce

Stakeholders are investing heavily in their ability to curate appropriate data sets and devise advanced data-analytics capabilities to harness real-world evidence (RWE) across the entire pharma lifecycle—from drug discovery and development through product launch and commercialization.

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Opinion: Pediatricians and parents on the brink: This is their March 2020

STAT

In March 2020, as the Covid-19 pandemic swept across the United States, the nation’s pediatric providers and pediatric units immediately pitched in to treat adults sickened by this then-mysterious and deadly disease. But now that the pediatric community is facing its own March 2020 with the confluence of Covid-19, influenza, and respiratory syncytial virus (RSV), the response from outside this community has been slow.

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With FDA filing on the horizon, Karuna appoints new CEO

PharmaVoice

Allergan alum Bill Meury will take the helm as current CEO Steve Paul transitions to lead R&D.

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Addressing leadership barriers for women in tech and pharma

pharmaphorum

Contrary to Big Tech, historically the pharmaceutical industry has had a good reputation for being a female-positive industry. However, both industries share a common problem: failure to provide women with C-suite opportunities. In fact, women hold only 11% of executive positions at Silicon Valley companies. The biopharma industry is worse, with women only accounting for 8% of CEO roles.

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Oligonucleotide synthesis market to reach $16.7 billion by 2027

European Pharmaceutical Review

According to a new market report by ResearchAndMarkets, the global oligonucleotide synthesis market is projected to reach $16.7 billion by 2027 during the forecast period, due to the rise in ongoing clinical trials for oligonucleotide-based therapies in key therapeutic sectors such as oncology. The research projected a compound annual growth rate (CAGR) of 16.8 percent from $7.7 billion in 2022.