Sat.Jun 22, 2024 - Fri.Jun 28, 2024

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Three months into bird flu outbreak in U.S. dairy cows, experts see deep-rooted problems in response

STAT

Three months since an outbreak of avian influenza in U.S. dairy cattle was declared, the country is failing to take the necessary steps to get in front of the virus and possibly contain its spread among cows, according to interviews with more than a dozen experts and current and former government officials. The country still does not have a sufficient testing infrastructure in place, nor a full understanding of how the virus is moving within herds and to new herds, experts say.

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Trick of the Trade: Ultrarapid adenosine push for SVT with a pressure bag

ALiEM - Pharm Pearls

With some things in life, speed is everything. Adenosine is one of those things. With an ultrafast half-life estimated to be between 0.6 to 10 seconds [1], parenterally administered adenosine needs to reach the cells of the AV-node and cardiac pacemaker cells in an expedited fashion to facilitate the termination of supraventricular tachycardias (SVTs).

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Can Moderna’s COVID-flu combo shot improve flagging vaccination rates?

PharmaVoice

A COVID and flu duo could ease manufacturing and administration, potentially driving higher vaccination rates, said Moderna’s VP of North American medical affairs.

Vaccines 276
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These microscopic tunnels are a goldmine for new medicines

BioPharma Dive

A growing cohort of biotechs, from Biohaven to Neurocrine to Jazz, hope research on ion channels will bring them new drugs and big business — much like it has done for Vertex.

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Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

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Surgeon general declares gun violence a public health crisis

STAT

Firearm violence is officially a public health crisis in the U.S. — Surgeon General Vivek Murthy says so. In a new advisory published on Tuesday, Murthy calls attention to the health toll of gun violence, describing the size of the crisis while laying out a roadmap of research and policy interventions to curb its effects. “My hope is that framing just the profound impact and pervasive impact of gun violence in our country … can firmly take it out of the realm of politics and

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EM Match Advice 44: Approaching your EM sub-internship clerkship – “Just gotta roll with it”

ALiEM - Pharm Pearls

Dr. Sara Krzyzaniak (podcast host and Stanford University PD) and Dr. Michelle Lin (ALiEM Founder/UCSF) are joined by Dr. Jessica Bod (Yale University Clerkship Director and 2024 CDEM Clerkship Director of the Year award winner) in this episode to discuss how one might approach their emergency medicine sub-internship. Dr. Bod shares her her wealth of experience and wisdom to provide not only general advice but also answers more detailed questions like: What are some things NOT to do on a rotatio

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‘Skinny jabs’: weight-loss drugs set for new boom as generic versions emerge

The Guardian - Pharmaceutical Industry

Alternatives to costly Wegovy and Saxenda will make such treatments more widely available worldwide Ozempic maker invests $4bn to meet US ‘skinny jab’ demand Medicines that enable dramatic weight loss are set to experience a new boom in uptake, experts have said, as the first generic versions hit the market this week at a lower cost than the original drugs.

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By the numbers: America’s alcohol-related health problems are rising fast

STAT

In the pit of the pandemic, with no one to see and nowhere to go, and horrors unfolding daily outside the front door, there was for many a reliable bright spot: the 5 p.m. drink that would mark the end of the workday. Drinking, which was already on the rise before 2020, became a coping mechanism for overburdened parents, burnt-out workers, the traumatized, and the bored.

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Zealand Pharma rakes in $1bn in funding for obesity drugs

pharmaphorum

Fresh from reporting encouraging results with its obesity drug candidate petrelintide, Zealand Pharma has raised an impressive $1 billion from a new share offering.The Danish biotech started the fundraising process earlier this week with an expectation of raising $900 million but easily overshot that target, evidence once again of huge investor interest in companies developing a new generation of obesity drugs.

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After 33 years, Geron’s first approval marks a turn in Nobel-winning science

PharmaVoice

The decades-long story of how a first-in-class blood cancer treatment went from bench to bedside.

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5 Reasons to Upgrade Your Pharmacy Management Software

Are you still using workarounds to manage your daily operations? To achieve peak performance, it's time to explore other options for specialty and infusion pharmacy software. Streamline pharmacy operations and improve clinical performance with automated processing, real-time data exchange, and electronic decision support. Download this helpful infographic to: Drive efficiency and patient adherence from referral receipt to delivery and ongoing care – all with our Pharmacy Cloud.

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AstraZeneca’s Tagrisso approved in Japan for lung cancer treatment

Pharmafile

AstraZeneca has announced that Tagrisso (osimertinib) in combination with pemetrexed and platinum-based chemotherapy has been approved in Japan for the first line treatment of adult patients with locally advanced or metastatic epidermal growth factor receptor-mutated (EGFRm) non-small cell lung cancer (NSCLC) whose tumours have exon 19 deletions or exon 21 mutations.

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STAT+: Supreme Court rejects Purdue bankruptcy plan

STAT

The U.S. Supreme Court rejected a controversial bankruptcy deal in which the owners of Purdue Pharma sought to contribute up to $6 billion in exchange for immunity from further lawsuits. The ruling means the company and its creditors — numerous states, cities and counties, as well as Native American governments — will have to negotiate a new settlement.

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Digital twins in healthcare and drug discovery: From idea to success stories

pharmaphorum

Explore how digital twins are transforming healthcare and drug discovery, with success stories showcasing their impact in the biopharma industry. Learn about their journey from concept to real-world applications.

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After an obesity deal with Novo, Omega’s new business head is on the hunt for more partners

PharmaVoice

With a career focused on striking deals, Kaan Cartel is hoping to lead the Flagship-backed biotech with an mRNA platform into its next phase of growth.

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Women with a common hormonal disorder have few good treatment options. Could GLP-1 drugs help?

BioPharma Dive

Obesity drugs like Wegovy are proving useful in many other diseases. Polycystic ovary syndrome, a chronic condition that can cause infertility, may be one.

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Infant deaths increased after Texas banned abortion in early pregnancy

STAT

Since Texas’ ban on abortion went into effect, infant deaths in the state increased by nearly 13%, according to a new analysis published on Monday in JAMA Pediatrics. In the rest of the country, infant mortality increased less than 2% over the same period. “We had read the literature that was showing an association [of infant death increases] with prior abortion restrictions or states that are hostile to abortion,” said lead author Alison Gemmill, a demographer and perinatal

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Debate: Trump lauds mifepristone ruling, Biden touts IRA win

pharmaphorum

In a US Presidential debate that was low on policy substance and high on hyperbole, falsehoods, and personal attacks, pharma industry issues played a minor role, but did crop up in ways both predictable (President Joe Biden touting the drug pricing provisions of the Inflation Reduction Act) and surprising (former President Donald Trump coming out in support of the Supreme Court's mifepristone ruling).

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Hack Your Hormones With Zenith Supplement | A Comprehensive Weight Loss Solution

Welltopia Pharmacy

Zenith supplement is a new and effective weight loss solution for people suffering from overweight problems. Weight loss is a significant health challenge that affects millions of people worldwide. The prevalence of obesity and overweight conditions has surged, leading to various health complications such as diabetes, cardiovascular diseases, and joint problems.

Diabetes 111
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PCPA president defends multidisciplinary team as doctors ask for ARRS funding

The Pharmacist

The president of the Primary Care Pharmacy Association (PCPA) has said he 'would not wish' Additional Roles Reimbursement Scheme (ARRS) or Pharmacy First funding 'to be subsumed' into core general practice funding, as called for recently by the Doctors' Association UK (DAUK). In a 10-point manifesto presented to prospective MPs last week, the DAUK’s GP […] The post PCPA president defends multidisciplinary team as doctors ask for ARRS funding appeared first on The Pharmacist.

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Michigan launches first effort of its kind to detect silent bird flu infections in farmworkers

STAT

Michigan has led the nation in making inroads with its farmers as it has worked to contain spread of H5N1 bird flu infections in dairy cows. Now the state’s health authorities are trying to do the same in looking for undetected infections among farmworkers. The Michigan Department of Health and Human Services is working with an undisclosed number of farms to try to assess the risk to workers of becoming infected with the virus, which has spread to at least 25 farms in the state in the pas

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We want your feedback!

pharmaphorum

Take part in the pharmaphorum reader survey 2024 and share your views on the latest trends and developments in the pharmaceutical industry. Your input helps us tailor our publication to meet your needs.

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First-of-its-kind Intellia data suggest CRISPR drug could be given more than once

BioPharma Dive

The findings provide early proof that multiple doses of a gene editing medicine can be safely administered with additive effects, overcoming a key constraint of the complex therapies.

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Analysis: Pharmacy closures risk exacerbating digital divides

The Pharmacist

EXCLUSIVE Pharmacy closures in deprived areas are not only impacting physical access to a local pharmacy. They may also be exacerbating health inequalities for those who are less likely to access online services. The Pharmacist’s exclusive mapping of pharmacy closures suggested that the most deprived areas in England have lost nearly five times as many […] The post Analysis: Pharmacy closures risk exacerbating digital divides appeared first on The Pharmacist.

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Opinion: To reduce suicide, primary care and mental health clinicians need to work together. Congress can help that happen

STAT

Suicide rates in the United States increased approximately 36% between 2000 and 2022, according to updated data from the National Center for Health Statistics. Suicide was responsible for just under 50,000 deaths in 2022 (the last year with complete statistics) — an all-time high. As this appalling trend continues, offering mental health assessments and care in primary care settings could help save lives.

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House committee backs some Medicare cover for obesity drugs

pharmaphorum

The House Ways and Means Committee in the US voted in favour of a new bill which would end a two-decade-long restriction on the coverage of drugs to treat obesity under Medicare.The Treat and Reduce Obesity Act of 2023 (TROA) was originally intended to overturn the restriction completely, but has been hugely scaled back in its scope.

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AstraZeneca’s Tagrisso receives approval in Japan for lung cancer

Pharmaceutical Technology

AstraZeneca has received Japanese approval for Tagrisso plus chemotherapy as first-line treatment for non-small cell lung cancer (NSCLC).

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Best Practices for Drug Patent Portfolio Management

Drug Patent Watch

Introduction Patent portfolios are critical assets for pharmaceutical companies, providing market exclusivity and protecting revenue streams for drug products. Effective management of drug patent portfolios requires strategic planning, ongoing evaluation, and adaptation to the evolving pharmaceutical landscape. This article explores key best practices for optimizing drug patent portfolios to maximize value and maintain competitive advantage.

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Stop blindly allowing MA plans to use AI to deny care, lawmakers urge Biden administration

STAT

A bipartisan group of lawmakers is urging the Biden administration to prohibit Medicare Advantage insurers from using artificial intelligence tools to deny care until it completes a systematic review of their accuracy and effects on patients. In a letter sent Tuesday, the lawmakers cited a STAT investigation in calling on the Centers for Medicare and Medicaid Services to beef up oversight of AI and algorithmic tools that discriminate against old and sick patients.

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Verona’s first-in-class COPD drug ‘could transform market’

pharmaphorum

Verona Pharma has claimed FDA approval for its chronic obstructive pulmonary disease (COPD) drug ensifentrine, which has been tipped as a future blockbuster.The first-in-class dual phosphodiesterase (PDE) 3/4 inhibitor – now given the somewhat tongue-twisting brand name of Ohtuvayre – is the first inhaled product with a novel mechanism of action available for the maintenance treatment of COPD in more than 20 years, according to Verona.

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Dr Reddy’s to acquire Nicotinell and related portfolio

Express Pharma

Dr. Reddy’s Laboratories announced that its subsidiary Dr. Reddy’s Laboratories SA has signed a definitive agreement with Haleon, a consumer healthcare company, for the purchase of shares of Northstar Switzerland SARL, a Haleon group company, to acquire Haleon’s global portfolio of consumer healthcare brands in the Nicotine Replacement Therapy (“NRT”) category outside of the United States.

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Supreme Court overturns Chevron doctrine, limiting reach of federal agencies

BioPharma Dive

Federal courts will no longer have to defer to agency regulations for interpretation of ambiguous statutes, a ruling that could have significant impact on the FDA and CMS.

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Journals issue corrections noting vaping researchers’ undisclosed ties to Juul

STAT

WASHINGTON — A journal published by the American Medical Association has corrected four articles from two of the nation’s top tobacco researchers, Ray Niaura and David Abrams, after STAT uncovered undisclosed ties the New York University professors had with the e-cigarette company Juul. The articles corrected Tuesday by JAMA Network Open include a highly cited study comparing the level of toxic substances users of e-cigarettes are exposed to versus smokers of combustible cigarettes

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Cell and gene therapies and the tricky question of patient support

pharmaphorum

Explore the complexities of patient support in the realm of cell and gene therapies. Learn about the challenges and strategies for providing effective patient assistance in this cutting-edge field.

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10th edition of PharmaLytica held in Hyderabad

Express Pharma

The 10th edition of PharmaLytica, organised by Informa Markets in India concluded at HITEX, Hyderabad. With a focus on redefining the pharmaceutical industry in the post-COVID era, PharmaLytica 2024 offered a platform for stakeholders to engage in discussions covering the full spectrum of pharma machinery and packaging, lab analytical and cleanroom solutions, and pharmaceutical ingredients.

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Pride in Pharmacy: confidence in providing equitable healthcare

The Pharmacist

Reuben Dunbar shares how the Pride in Pharmacy training and support programme aims to help pharmacy teams feel confident in the ways they can provide more equitable healthcare to LGBTQ+ people. Why is Pride in Pharmacy important for both pharmacy teams and patients? The aim of Pride in Pharmacy is for every LGBTQ+ person to […] The post Pride in Pharmacy: confidence in providing equitable healthcare appeared first on The Pharmacist.

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