Sat.Nov 26, 2022 - Fri.Dec 02, 2022

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5 enduring mysteries of the Barry and Honey Sherman murders

PharmaVoice

After nearly five years, the homicide case involving pharma billionaires continues to perplex investigators.

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STAT+: Alzheimer’s researchers try out an unfamiliar sensation: optimism

STAT

SAN FRANCISCO — Scientific meetings about Alzheimer’s disease can be funereal affairs, with researchers from around the world gathering in hopes that the latest in a long line of negative clinical trials might light the path to a long-awaited success. This year was different. Nearly 2,000 people showed up to the Clinical Trials in Alzheimer’s Disease meeting, a conference record, to hear about lecanemab, a drug from Eisai and Biogen that appears to have broken the decades-lo

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Five Things Pharmacists Should Know About Ventilator Associated Pneumonia (VAP)

ID Stewardship

In this article a pharmacist with advanced training and experience in infectious diseases discusses five things pharmacists should know about ventilator associated pneumonia (VAP). Authored By: Lucia Rose, PharmD, BCIDP. Article Posted 1 December 2022. It was the fall of 2009; I was a proud PGY-1 resident at UMass Medical Center rounding with a large team in the ICU.

Hospitals 139
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Touchlight receives funding to develeop DNA vaccine platform

Pharma Times

Bill & Melinda Gates Foundation grant will boost potential of nanoparticle-formulated doggybone DNA

Vaccines 129
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Navigating Payroll Compliance: Future-Proofing Payroll in an Evolving Regulatory Landscape

Speaker: Jennifer Hill

Payroll compliance is a cornerstone of business success, yet for small and midsize businesses, it’s becoming increasingly challenging to navigate the ever-evolving landscape of federal, state, and local regulations. Mistakes can lead to costly penalties and operational disruptions, making it essential to adopt advanced solutions that ensure accuracy and efficiency.

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Non-toxic and addiction free: The promise of a new pain med

PharmaVoice

Why South Rampart Pharma’s novel new molecule could be a key to solving the global pain epidemic.

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After three years in prison, ‘CRISPR babies’ scientist is attempting a comeback

STAT

He Jiankui, the Chinese biophysicist who created the first gene-edited children , had been quiet since completing a three-year prison sentence in April, leaving many to wonder whether he had plans to return to scientific research. Earlier this month, we got his answer. On Nov. 9, He posted photos to Twitter of himself sitting at a computer in a white office.

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More Trending

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Eisai and Biogen present promising lecanemab study results

Pharma Times

Phase 3 research shows that Alzheimer’s disease treatment meets primary and secondary endpoints

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Avoiding a ‘bad trip’ in psychedelic clinical trials

PharmaVoice

Psychedelic drug trials pose a number of challenges, but researchers can take these steps to boost patient safety.

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STAT+: Detailed data on Alzheimer’s therapy from Eisai, Biogen hold up to scientific scrutiny

STAT

SAN FRANCISCO — A closely watched new treatment for Alzheimer’s disease held up to scrutiny in a detailed scientific presentation Tuesday, as its developers, partners Eisai and Biogen, begin the lengthy process of turning this medicine into what they hope could be a groundbreaking therapy. The drug, lecanemab, slowed the cognitive and functional decline of patients with early-stage Alzheimer’s by 27% relative to placebo in a roughly 2,000-volunteer clinical trial.

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Word of the Month: What is TRIPS?

PhRMA

What is TRIPS?

Vaccines 117
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From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

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C4XD signs NRF2 Activator deal with AstraZeneca

Pharma Times

C4XD will receive milestone payments worth up to $16m ahead of the first clinical trial

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Healthcare tech’s biggest busts

PharmaVoice

The metaverse, blockchain, DCTs and more — here are some of the most recent fails in healthcare tech.

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Opinion: Congress: Close the gap between funding for nutrition research and the toll diet-related disease takes on Americans

STAT

You are what you eat. Every year, new scientific discoveries make clear that food is critical to health. In recent years, nutrition research trials have shown that a Mediterranean diet reduces cardiovascular disease; ultra-processed foods increase weight gain; omega-3 fatty acids improve IQ in preterm babies; cocoa prevents heart attacks; and vitamin D supplements do — well, almost nothing.

Immunity 331
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First adaptive clinical trial for flu

European Pharmaceutical Review

A £2.9 million, UK-wide adaptive platform trial (APT) has been launched to find effective treatments for people hospitalised with severe flu for the first time, testing multiple options simultaneously in thousands of people then modifying treatments quickly. The research aims to find treatments that reduce deaths from flu and prevent patients needing intensive care.

Hospitals 115
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Why Every Small Business Needs an HCM Solution: A Comprehensive Guide

Managing HR tasks like payroll, compliance, and employee data can overwhelm small businesses. That’s where a Human Capital Management (HCM) solution comes in. Our eBook, Why Every Small Business Needs an HCM Solution: A Comprehensive Guide , shows how an HCM system automates tedious processes, ensuring your business stays compliant and efficient. You’ll learn how to simplify payroll, eliminate costly errors, and empower your employees with self-service tools.

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Healthcare leaders warn about unsustainable pressure on mental health services

Pharma Times

Patients and service users routinely struggle to access mental healthcare across the NHS

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5 final FDA action dates to watch this year

PharmaVoice

A potential flurry of regulatory activity could be on the horizon yet this year — and several key drug approvals are at stake.

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Opinion: Breakthrough Therapies Act: Good idea, wrong solution

STAT

The Breakthrough Therapies Act , recently proposed by Senators Rand Paul (R-Ky.) and Cory Booker (D-N.J.) as a way to expand access for therapeutic purposes to potentially beneficial but highly regulated Schedule I substances like psilocybin and LSD, has the right underlying idea but provides a solution that is wrong. The act would automatically reclassify to Schedule II any experimental medicine designated by the Drug Enforcement Agency as a Schedule I controlled substance — defined as a

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Steps to building a more patient-centric industry

pharmaphorum

Lack of access, strict regulations, and demanding schedules have made it extremely difficult for patients to participate in clinical trials. A 2018 NIH survey found that patients felt clinical trial participation to be inconvenient and burdensome, and nearly half (49.0%) said it disrupted their daily routine. In 2021, a CISCRIP Perceptions and Insights Study reported more disruption to daily routines compared to previous years, citing length of visits, travel, and diagnostic tests as top burdens

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Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

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Immutep in clinical trail collaboration with Merck KGaA and Pfizer

Pharma Times

Research will focus on eftilagimod alpha and avelumab for the treatment of urothelial cancer

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Evommune’s unique method of drug discovery is more than skin deep

PharmaVoice

The biotech is using human skin squares from plastic surgery to find the best immunological molecules for solving conditions like dermatitis.

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In Philadelphia, ‘tranq’ is leaving drug users with horrific wounds. Other communities are bracing for the same

STAT

PHILADELPHIA — The volunteers were handing out the staples of harm reduction: safe injection and smoking kits, condoms, and Narcan, the opioid overdose reversal medication. Down the line, they were distributing hats, socks, coats, and blankets to the people who use drugs who came to this outreach event on a recent Saturday, a bright, cold morning a few days before Thanksgiving.

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AstraZeneca enters $320m deal to acquire Neogene

Pharmaceutical Technology

AstraZeneca has signed an agreement for the acquisition of all outstanding equity of clinical-stage biotechnology firm Neogene Therapeutics in a deal totalling up to $320m. Neogene focuses on discovering, developing and producing next-generation T-cell receptor therapies (TCR-Ts) that provide a new cell therapy approach for fighting cancer. TCR-Ts can detect intracellular targets such as cancer-specific mutations to unlock targets which were not accessible earlier using cell therapies.

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Best Practices to Streamline Compensation Management: A Foundation for Growth

Speaker: Joe Sharpe and James Carlson

Payroll optimization can be one of the most time-consuming and complex factors of small business management. Yet, organizations that crack the code on streamlining employee compensation often discover innovative avenues for growth. With the right strategies in place, outsourcing and streamlining payroll processes can result in substantial time and resource savings.

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Respiratory vaccination candidate tested in German hospitals

Pharma Times

Novel tuberculosis vaccine tested in a large phase 3 trial against severe respiratory infection disease

Vaccines 117
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10 of our most popular articles in 2022

PharmaVoice

Methadone, rock ‘n’ roll, clinical trial overhauls — here’s a look at our most-read stories of the year.

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STAT+: AAM’s Dan Leonard, president of generic drug lobby, ousted

STAT

The generic drug industry’s lobbying group, the Association for Accessible Medicines, fired its president Dan Leonard, two sources familiar with the decision said Friday evening. It was not immediately clear why Leonard was fired, and AAM didn’t immediately respond to a request for comment. The sources said its members were frustrated that it was late to engage when Congress was debating the Inflation Reduction Act, which gives Medicare the power to negotiate drug prices.

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Supporting the era of green pharmaceuticals in the UK

pharmaphorum

According to a report by the Office of Health Economics (OHE), commissioned by the Association of the British Pharmaceutical Industry (ABPI), immediate action must be taken by governments, health systems, and companies to secure the era of green pharmaceuticals. ‘Supporting the era of green pharmaceuticals in the UK’ highlights that, while Britain can play a leading role in the sustainability agenda for pharmaceuticals, action must also be taken on a global scale to ensure impact.

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Enhance Healthcare Efficiency With Top Payroll & HCM Services

Running a healthcare facility requires precision and care, not just for patients but also for your staff. Our guide, "A Buyer’s Guide to Payroll & HCM Services," helps healthcare providers choose the best provider. Efficient payroll management ensures timely, accurate payments, critical for maintaining staff morale and trust. Compliance support helps navigate complex healthcare regulations and avoid costly fines.

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Almirall joins project to allow study participants to use trial data

Pharma Times

Project involves 27 partners including patient associations, hospitals and universities

Hospitals 116
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Woman of the Week: Surface Oncology’s Dr. Alison O’Neill

PharmaVoice

With more than two decades of experience in oncology R&D, Dr. Alison O’Neill is helping Surface unlock the potential of next-gen immunotherapies by targeting the tumor microenvironment.

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Stanford is investigating its president over allegations of research misconduct

STAT

Stanford University has opened an investigation into its president, Marc Tessier-Lavigne, a renowned neuroscientist and former biotech executive, for research misconduct after experts alleged papers on which he was an author included altered images, the university confirmed. The university’s board will oversee the investigation.

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Expanding ketamine’s horizons to treat rare neurological disorders

Pharmaceutical Technology

For several decades, researchers have been investigating the role of ketamine in treating depression. Now, efforts are underway to study ketamine’s effects in Parkinson’s disease, fibromyalgia, and Rett syndrome. On November 14, the Canadian developer PharmaTher announced positive data from a Phase I/II study where ketamine was used to treat levodopa-induced dyskinesia in Parkinson’s disease.

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5 Reasons to Upgrade Your Pharmacy Management Software

Are you still using workarounds to manage your daily operations? To achieve peak performance, it's time to explore other options for specialty and infusion pharmacy software. Streamline pharmacy operations and improve clinical performance with automated processing, real-time data exchange, and electronic decision support. Download this helpful infographic to: Drive efficiency and patient adherence from referral receipt to delivery and ongoing care – all with our Pharmacy Cloud.