December, 2024

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Opinion: The DEA’s 2025 quotas for opioids will leave seriously ill patients in pain

STAT

A woman sat in our emergency department in agonizing pain, feeling shaky, nauseous, and weak — drug withdrawal was setting in. But she wasn’t a “junkie” or even a recreational drug user. She was in her mid-60s with advanced cancer in her ovaries that had spread to her abdomen, causing unbearable pain. She was my patient — let’s call her Teresa.

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A biotech’s race to tackle the most severe hepatitis

PharmaVoice

Bluejay Therapeutics is one of just a handful of companies developing treatments for hepatitis D.

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SAEM Clinical Images Series: Not Your Average Eczema

ALiEM - Pharm Pearls

A 3-year-old male with a history of severe atopic dermatitis presented for facial rash and hand pain. Mom had been applying Aquaphor and Vaseline several times a day. On the day of presentation, he woke up with a new rash over his face and hands which prompted the ED visit. He is up to date on childhood immunizations and is not prescribed any oral medications.

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Four in ten contractors warn their pharmacy may not survive the winter

The Pharmacist

Four in 10 pharmacy owners are worried that their business may not survive the winter, recent polling by Community Pharmacy England (CPE) suggests. Some 39% of contractors said they were 'very concerned' about their pharmacy business going into winter, warning that they were worried about having to close permanently. Meanwhile, 81% warned of longer waiting […] The post Four in ten contractors warn their pharmacy may not survive the winter appeared first on The Pharmacist.

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From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

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Bridging the gap between pharmaceutical research and market application: The role of universities for students

Express Pharma

The pharmaceutical industry is vital to healthcare, fostering innovation for life-saving medications and therapies. However, the journey from research to market application is complex, creating a gap between discoveries and their practical use in patient care. In this context, universities play a crucial role by equipping students with the skills and knowledge needed to translate pharmaceutical research into real-world applications.

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Genmab expands its pipeline with $630m Scancell deal

pharmaphorum

Genmab has licensed another anti-glycan antibody for cancer from UK biotech Scancell as it continues to expand its in-house pipeline.

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With Makary set to face FDA commissioner hearings, how deep do his industry ties run?

PharmaVoice

Dr. Marty Makary’s conflicts of interest could come into question before he is confirmed as the next FDA commissioner.

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SAEM Clinical Images Series: My Mom Could Not See

ALiEM - Pharm Pearls

An 87-year-old female with a history of hypertension, hyperlipidemia, chronic kidney disease stage IIIB, type 2 diabetes mellitus, and schizophrenia presented for evaluation due to sudden visual loss in her right eye, which began 12 hours before she arrived at the emergency department. She has experienced a sudden loss of vision in her right eye for more than six hours.

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EMCrit 389 – Massive Transfusion Update and Hemostatic Resuscitation

EMCrit Project

John Holcomb, author of the PROPPR trial, on massive transfusion in 2024 EMCrit Project by Scott Weingart, MD FCCM.

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Race for approval of first oral GLP-1R drug in obesity intensifies with four in phase III trials: GlobalData

Express Pharma

In recent years, GLP-1 receptor (GLP-1R) products have gained immense popularity. Currently, four innovative GLP-1Rs are approved worldwide for obesity, all of which are injectables. This leaves a gap in the obesity market for an oral GLP-1R product. 63 drugs are in active development, with four Phase III products racing to earn the inaugural approval in this untapped market, says GlobalData.

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Why Every Small Business Needs an HCM Solution: A Comprehensive Guide

Managing HR tasks like payroll, compliance, and employee data can overwhelm small businesses. That’s where a Human Capital Management (HCM) solution comes in. Our eBook, Why Every Small Business Needs an HCM Solution: A Comprehensive Guide , shows how an HCM system automates tedious processes, ensuring your business stays compliant and efficient. You’ll learn how to simplify payroll, eliminate costly errors, and empower your employees with self-service tools.

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Leriglitazone meets endpoint in trial for cerebral adrenoleukodystrophy

Pharma Times

Promising results set stage for European marketing authorization

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CDC finds no evidence of bird flu virus in California toddler

STAT

Testing of samples taken from a child in California thought to have contracted H5N1 bird flu after drinking raw milk turned up no evidence of influenza viruses, the Centers for Disease Control and Prevention said Thursday.  A test run on a sample from the child — who went to a Marin County emergency department last week with a fever and vomiting — had been positive there for flu A.

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Merck’s RSV antibody could soon paddle into the rough waters of a crowded market

PharmaVoice

A new antibody from Merck would join a market teeming with new entries, but plenty of regulatory and financial uncertainty.

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Lilly’s Zepbound beats Novo’s Wegovy in high-stakes obesity drug trial

BioPharma Dive

Results from the head-to-head study showed treatment with Zepbound resulted in 47% greater relative weight loss than Wegovy, a finding that could advantage Lilly in the companies’ market competition.

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Best Practices to Streamline Compensation Management: A Foundation for Growth

Speaker: Joe Sharpe and James Carlson

Payroll optimization can be one of the most time-consuming and complex factors of small business management. Yet, organizations that crack the code on streamlining employee compensation often discover innovative avenues for growth. With the right strategies in place, outsourcing and streamlining payroll processes can result in substantial time and resource savings.

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Deadline looms for post-Brexit label changes for UK meds

pharmaphorum

The MHRA has reminded pharma companies that from 1st January all medicines sold in the UK will have to comply with new labelling requirements

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Reprieve for Chinese biotechs as BIOSECURE Act left out of key bill

Pharmaceutical Technology

Shares in WuXi AppTec, one of those implicated in the Chinese biotech blacklisting legislation, surged following the omission.

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Cellenkos presents promising phase 1b data for CK0804 in myelofibrosis

Pharma Times

New cell therapy shows potential in treating advanced blood disorder

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STAT+: Next-gen obesity treatment from Novo Nordisk misses mark in pivotal trial

STAT

Novo Nordisk’s next-generation obesity candidate led patients to lose a substantial amount of weight in a pivotal study but fell short of expectations, results that cast into doubt the future competitiveness of the company in the booming weight loss market. The treatment, called CagriSema, led patients to lose 20% of their weight at 68 weeks in a late-stage study when looking at all participants, including those who dropped out, Novo said Friday.

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Enhance Healthcare Efficiency With Top Payroll & HCM Services

Running a healthcare facility requires precision and care, not just for patients but also for your staff. Our guide, "A Buyer’s Guide to Payroll & HCM Services," helps healthcare providers choose the best provider. Efficient payroll management ensures timely, accurate payments, critical for maintaining staff morale and trust. Compliance support helps navigate complex healthcare regulations and avoid costly fines.

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Will the ‘anti-woke’ movement derail DEI efforts in pharma?

PharmaVoice

Amid the DEI backlash in corporate America, pharma leaders are quietly adjusting tactics.

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Novo’s next-gen obesity drug misses expectations in closely watched trial

BioPharma Dive

Novo shares lost nearly a quarter of their value after an experimental combination treatment called cagrisema fell short of the bar set by executives.

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Targeted therapies and improved diagnostics remain needs unmet in T2-low asthma

Express Pharma

Despite advances in biologic therapies for severe asthma, significant unmet needs in asthma management remain, specifically with T-helper cell type 2 (T2)-low asthma, a subtype lacking typical inflammatory biomarkers. T2-low asthma presents unique challenges due to the absence of eosinophils and immunoglobulin E (IgE), which complicates both diagnosis and treatment.

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'Concerning reports' of scam websites targeting weight loss and other shortage meds

The Pharmacist

Fake online pharmacies are targeting vulnerable patients whose medicines are in short supply, including obesity drugs, ADHD medication and hormone replacement therapy (HRT), the Royal Pharmaceutical Society (RPS) has reported. The Medicines and Healthcare products Regulatory Agency (MHRA) said such fraudulent supply was the work of 'organised criminal gangs', while the General Pharmaceutical (GPhC) warned […] The post 'Concerning reports' of scam websites targeting weight loss an

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Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

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Antag Therapeutics secures €80 million in weight loss therapy financing

Pharma Times

Versant Ventures leads investment round to advance drug

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STAT+: AI versus AI: The emerging arms race over health insurance denials

STAT

Like many Americans, Holden Karau said she was fed up with health insurance. The software engineer’s disillusionment began in 2019, when her insurer, UnitedHealthcare, balked at covering physical therapy after she was hit by a car and could not walk. She said the hassles piled on stress, forced her to pay more out of pocket, and delayed access to care she needed to recover from multiple broken bones.

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Milk-based therapies could be coming. This biotech CEO is aiming to lead the way.

PharmaVoice

Intrinsic Medicines is entering phase 2 trials in Parkinson’s disease and IBS for its human milk oligosaccharide drug candidates next year.

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Diabetes advocacy group discourages use of compounded GLP-1 drugs

BioPharma Dive

The ADA recommended doctors avoid prescribing unapproved, off-brand versions of drugs like Wegovy, wading into a dispute that has gripped the FDA and compounding pharmacies over the past few months.

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5 Reasons to Upgrade Your Pharmacy Management Software

Are you still using workarounds to manage your daily operations? To achieve peak performance, it's time to explore other options for specialty and infusion pharmacy software. Streamline pharmacy operations and improve clinical performance with automated processing, real-time data exchange, and electronic decision support. Download this helpful infographic to: Drive efficiency and patient adherence from referral receipt to delivery and ongoing care – all with our Pharmacy Cloud.

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How automating flow cytometry is revolutionising cancer diagnosis and treatment

pharmaphorum

Discover how the automation of flow cytometry is transforming cancer diagnosis and treatment for breast, prostate, endometrial, pancreatic, kidney, and melanoma cancers. Explore the latest advancements in the field.

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SAEM Clinical Images Series: This Rash Came Out of No Where

ALiEM - Pharm Pearls

A 26-year-old male with a past medical history of eczema presented to the Emergency Department with a rash for two days. The patient stated he first noticed a rash on his right arm that rapidly spread to his face, chest, and left arm. He reported having similar rashes before but never to this extent. The patient stated he was given Bactrim and amoxicillin about one month ago for another rash, though he was unsure of the diagnosis.

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NICE endorses Neuraxpharm’s ublituximab for treating MS

Pharma Times

New antibody therapy shows promise in managing condition

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STAT+: Ohio court sides with CVS, Walmart, and Walgreens in opioid case

STAT

The Ohio Supreme Court ruled that three of the largest pharmacy chain operators in the U.S. could not be held liable under a state nuisance law for contributing to the long-running opioid crisis. In a 5-to-2 vote, the court determined that the law barred two Ohio counties from obtaining a $650.9 million judgement that was won in a federal court against CVS Health, Walgreens, and Walmart.

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Big Pharma’s new DTC play: partnering with digital health providers

PharmaVoice

The pharma giant is looking for another edge in the competitive weight loss market through DTC expansion.

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