June, 2024

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STAT+: Supreme Court rejects Purdue bankruptcy plan

STAT

The U.S. Supreme Court rejected a controversial bankruptcy deal in which the owners of Purdue Pharma sought to contribute up to $6 billion in exchange for immunity from further lawsuits. The ruling means the company and its creditors — numerous states, cities and counties, as well as Native American governments — will have to negotiate a new settlement.

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From Collision to Clarity: PECARN cervical spine injury prediction rule for injured children

ALiEM - Pharm Pearls

For years, adult literature has provided clear guidelines for cervical spine imaging through the NEXUS and Canadian C-spine Rule (CCR) tools. These have been invaluable in helping clinicians decide when to image the neck in trauma patients. Similarly, the Pediatric Emergency Care Applied Research Network (PECARN) has developed robust tools for assessing blunt head trauma in children.

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Avoiding the pharma ‘junk pile’ with launch readiness, pipeline rigor and ‘quick kills’

PharmaVoice

Drug launches have underperformed expectations at a high rate, and pharmas need to get better at thinning the pipeline to make room for the real wins, says a life sciences consultant.

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Modifier gene therapy – clinical development and manufacturing considerations

European Pharmaceutical Review

Tell us about Ocugen’s lead programme, OCU400. What’s the latest and what’s next? OCU400 is a modifier gene therapy aimed at treating retinitis pigmentosa and Leber congenital amaurosis (LCA). In April 2024, Ocugen received US Food and Drug Administration (FDA) clearance to initiate the Phase III liMeliGhT clinical trial for OCU400 for retinitis pigmentosa.

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From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

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New data showcase promise, growing pains of CAR-T in autoimmune disease

BioPharma Dive

One expert described trial results presented at EULAR last week as “unprecedented.” But reports of relapses in some patients drew questions about the therapies’ ultimate potential.

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Pharmacists with a disability: Standing Up for Sitting Down campaign

The Pharmacist

When pharmacists with a disability told the Pharmacists’ Defence Association (PDA) they were having problems with suitable adjustments in their workplace, a campaign was launched to raise awareness of what employers need to consider. Liz Larkin reviews the issues. When members of the PDA’s Ability Network named their campaign against disability discrimination, ‘Standing Up for […] The post Pharmacists with a disability: Standing Up for Sitting Down campaign appeared first on The Pharmacist

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Novavax seeks FDA approval for updated Covid-19 vaccine

Pharmaceutical Technology

Novavax has sought US FDA approval for an updated JN.1 version of its Covid-19 vaccine, NVX-CoV2705, for individuals aged 12 years and above.

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Regenerative cell therapy biotech uses IPO to blast into human trials

PharmaVoice

Bucking conventional fundraising, FibroBiologics’ CEO Pete O’Heeron explains why the biotech company bet on themselves in the public market.

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2024 Commonwealth Pharmacists Day -Pharmacists developing resilient and sustainable health systems

Commonwealth Pharmacists Association

2024 Commonwealh Pharmacists Day -Pharmacists developing resilient and sustainable health systems About the Day Welcome to the official page for Commonwealth Pharmacists Day, celebrated every year on the 16th of June! This year, we have chosen the theme: “Pharmacists developing resilient and sustainable health systems”.

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These microscopic tunnels are a goldmine for new medicines

BioPharma Dive

A growing cohort of biotechs, from Biohaven to Neurocrine to Jazz, hope research on ion channels will bring them new drugs and big business — much like it has done for Vertex.

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Why Every Small Business Needs an HCM Solution: A Comprehensive Guide

Managing HR tasks like payroll, compliance, and employee data can overwhelm small businesses. That’s where a Human Capital Management (HCM) solution comes in. Our eBook, Why Every Small Business Needs an HCM Solution: A Comprehensive Guide , shows how an HCM system automates tedious processes, ensuring your business stays compliant and efficient. You’ll learn how to simplify payroll, eliminate costly errors, and empower your employees with self-service tools.

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Two-thirds of pharmacies slash opening hours amid funding pressures

The Pharmacist

Almost two-thirds of pharmacies in England have decreased their opening hours since 2015, latest analysis from the National Pharmacy Association (NPA) has suggested. The research, based on a sample of 110 pharmacies, found that on average there has been a 6.1-hour (10%) reduction in opening hours for every pharmacy. The findings come as up to […] The post Two-thirds of pharmacies slash opening hours amid funding pressures appeared first on The Pharmacist.

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Michigan launches first effort of its kind to detect silent bird flu infections in farmworkers

STAT

Michigan has led the nation in making inroads with its farmers as it has worked to contain spread of H5N1 bird flu infections in dairy cows. Now the state’s health authorities are trying to do the same in looking for undetected infections among farmworkers. The Michigan Department of Health and Human Services is working with an undisclosed number of farms to try to assess the risk to workers of becoming infected with the virus, which has spread to at least 25 farms in the state in the pas

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‘Skinny jabs’: weight-loss drugs set for new boom as generic versions emerge

The Guardian - Pharmaceutical Industry

Alternatives to costly Wegovy and Saxenda will make such treatments more widely available worldwide Ozempic maker invests $4bn to meet US ‘skinny jab’ demand Medicines that enable dramatic weight loss are set to experience a new boom in uptake, experts have said, as the first generic versions hit the market this week at a lower cost than the original drugs.

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Don’t call it a comeback: Biotech’s CNS resurgence forges Big Pharma connections

PharmaVoice

Neuroscience pipelines are reawakening as biotechs prove to the pharma giants that the field is still worth the investment.

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Best Practices to Streamline Compensation Management: A Foundation for Growth

Speaker: Joe Sharpe and James Carlson

Payroll optimization can be one of the most time-consuming and complex factors of small business management. Yet, organizations that crack the code on streamlining employee compensation often discover innovative avenues for growth. With the right strategies in place, outsourcing and streamlining payroll processes can result in substantial time and resource savings.

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PulmCrit: Bilevel Sequence Intubation (BSI) – The new standard

EMCrit Project

introduction Bilevel Sequence Intubation (BSI) refers to initiation of noninvasive bilevel positive pressure ventilation with a backup rate prior to intubation (either using a BiPAP machine or a full-featured mechanical ventilator). BSI is distinct from traditional rapid sequence intubation (RSI), since BSI involves the delivery of machine-initiated, pressure-controlled breaths following administration of sedation and paralytics. […] EMCrit Project by Josh Farkas.

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Duchenne approval exposes FDA rift over Sarepta gene therapy

BioPharma Dive

Peter Marks’ decision to override the objections of agency staff and broaden use of Elevidys could have a “lasting impact” on gene therapy as well as the FDA, one analyst wrote.

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Digital twins in healthcare and drug discovery: From idea to success stories

pharmaphorum

Explore how digital twins are transforming healthcare and drug discovery, with success stories showcasing their impact in the biopharma industry. Learn about their journey from concept to real-world applications.

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Surgeon general declares gun violence a public health crisis

STAT

Firearm violence is officially a public health crisis in the U.S. — Surgeon General Vivek Murthy says so. In a new advisory published on Tuesday, Murthy calls attention to the health toll of gun violence, describing the size of the crisis while laying out a roadmap of research and policy interventions to curb its effects. “My hope is that framing just the profound impact and pervasive impact of gun violence in our country … can firmly take it out of the realm of politics and

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Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

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Pharmacy closures nearly five times higher in more deprived areas

The Pharmacist

EXCLUSIVE The most deprived areas in England have lost nearly five times as many community pharmacy premises as the least deprived areas in the last five years, new analysis from The Pharmacist has found. The 10% most deprived areas saw a net loss of around 250 local pharmacies between March 2019 and April 2024, while […] The post Pharmacy closures nearly five times higher in more deprived areas appeared first on The Pharmacist.

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AstraZeneca’s Tagrisso approved in Japan for lung cancer treatment

Pharmafile

AstraZeneca has announced that Tagrisso (osimertinib) in combination with pemetrexed and platinum-based chemotherapy has been approved in Japan for the first line treatment of adult patients with locally advanced or metastatic epidermal growth factor receptor-mutated (EGFRm) non-small cell lung cancer (NSCLC) whose tumours have exon 19 deletions or exon 21 mutations.

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EMCrit 377 – Breaking News – The PREOXI Trial changes everything about Preoxygenation for Intubations in the Critically Ill

EMCrit Project

the PREOXI trial validates what I have been saying for 15 years about preoxygenation for the critically ill patient EMCrit Project by Scott Weingart, MD FCCM.

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In review of Lilly Alzheimer’s drug, FDA staff focus on safety, patient selection

BioPharma Dive

The agency is seeking input from an advisory panel on whether donanemab is effective across different groups of Alzheimer's patients, and on an unusual dosing strategy used by Lilly.

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Enhance Healthcare Efficiency With Top Payroll & HCM Services

Running a healthcare facility requires precision and care, not just for patients but also for your staff. Our guide, "A Buyer’s Guide to Payroll & HCM Services," helps healthcare providers choose the best provider. Efficient payroll management ensures timely, accurate payments, critical for maintaining staff morale and trust. Compliance support helps navigate complex healthcare regulations and avoid costly fines.

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Zealand Pharma rakes in $1bn in funding for obesity drugs

pharmaphorum

Fresh from reporting encouraging results with its obesity drug candidate petrelintide, Zealand Pharma has raised an impressive $1 billion from a new share offering.The Danish biotech started the fundraising process earlier this week with an expectation of raising $900 million but easily overshot that target, evidence once again of huge investor interest in companies developing a new generation of obesity drugs.

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Infant deaths increased after Texas banned abortion in early pregnancy

STAT

Since Texas’ ban on abortion went into effect, infant deaths in the state increased by nearly 13%, according to a new analysis published on Monday in JAMA Pediatrics. In the rest of the country, infant mortality increased less than 2% over the same period. “We had read the literature that was showing an association [of infant death increases] with prior abortion restrictions or states that are hostile to abortion,” said lead author Alison Gemmill, a demographer and perinatal

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Paul Rees: 'We need to keep the pressure up'

The Pharmacist

The Pharmacist caught up with National Pharmacy Association (NPA) chief executive Paul Rees during today's ‘day of action’ to save community pharmacies, at a branch of Green Light Pharmacy in central London. Paul, tell us how the Save Our Pharmacies day of action campaign has been going today? For the first time ever, community pharmacies […] The post Paul Rees: 'We need to keep the pressure up' appeared first on The Pharmacist.

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Dr Reddy’s to acquire Nicotinell and related portfolio

Express Pharma

Dr. Reddy’s Laboratories announced that its subsidiary Dr. Reddy’s Laboratories SA has signed a definitive agreement with Haleon, a consumer healthcare company, for the purchase of shares of Northstar Switzerland SARL, a Haleon group company, to acquire Haleon’s global portfolio of consumer healthcare brands in the Nicotine Replacement Therapy (“NRT”) category outside of the United States.

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5 Reasons to Upgrade Your Pharmacy Management Software

Are you still using workarounds to manage your daily operations? To achieve peak performance, it's time to explore other options for specialty and infusion pharmacy software. Streamline pharmacy operations and improve clinical performance with automated processing, real-time data exchange, and electronic decision support. Download this helpful infographic to: Drive efficiency and patient adherence from referral receipt to delivery and ongoing care – all with our Pharmacy Cloud.

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AstraZeneca’s Tagrisso receives approval in Japan for lung cancer

Pharmaceutical Technology

AstraZeneca has received Japanese approval for Tagrisso plus chemotherapy as first-line treatment for non-small cell lung cancer (NSCLC).

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After ‘sobering’ FDA panel, psychedelics supporters wonder what’s next

BioPharma Dive

A vote against MDMA-assisted therapy set back a high-profile treatment. Proponents argue the panel offered few solutions to longstanding problems, making the path forward unclear.

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Pharmacogenomics and IVDR: Overcoming transition challenges

pharmaphorum

Understanding the challenges and opportunities in transitioning to IVDR for pharmacogenomics can be complex. Learn more about how to overcome these challenges effectively.

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By the numbers: America’s alcohol-related health problems are rising fast

STAT

In the pit of the pandemic, with no one to see and nowhere to go, and horrors unfolding daily outside the front door, there was for many a reliable bright spot: the 5 p.m. drink that would mark the end of the workday. Drinking, which was already on the rise before 2020, became a coping mechanism for overburdened parents, burnt-out workers, the traumatized, and the bored.

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Analysis: Pharmacy closures risk exacerbating digital divides

The Pharmacist

EXCLUSIVE Pharmacy closures in deprived areas are not only impacting physical access to a local pharmacy. They may also be exacerbating health inequalities for those who are less likely to access online services. The Pharmacist’s exclusive mapping of pharmacy closures suggested that the most deprived areas in England have lost nearly five times as many […] The post Analysis: Pharmacy closures risk exacerbating digital divides appeared first on The Pharmacist.