February, 2023

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STAT+: In about-face, Moderna vows Americans won’t have to pay for its Covid-19 vaccine

STAT

In an unexpected shift, Moderna has decided not to ask Americans to pay for its Covid-19 vaccine, a move that follows intense criticism over initial plans to charge $110 to $130 per dose after the company pivots from government contracts to commercial distribution. The vaccine maker released a brief statement that it “remains committed” to ensuring everyone in the U.S. has access to its Covid-19 shot, regardless of whether they have health insurance coverage.

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As clinical trials face a hiring crunch, here’s how research organizations can pivot

PharmaVoice

Staffing shortages are causing inefficiencies in clinical trials, but one leading CRO is finding ways to adapt.

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ACMT Toxicology Visual Pearl: Is the Silver Bullet for Refractory Vasoplegia Really Blue?

ALiEM - Pharm Pearls

What is the proposed mechanism for the pictured antidote when used as a pressor for refractory vasoplegic shock? Alpha-1-adrenergic agonist Angiotensin II receptor antagonist Nitric oxide/cyclic GMP pathway inhibition Vasopressin-1 receptor agonist Reveal the Answer Answer 3 – Inhibition along the nitric oxide (NO)/cyclic GMP pathway Background Vasoplegic shock is a maldistribution of blood flow and inadequate oxygen delivery secondary to an abnormally low systemic vascular resistance [1].

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CSL’s first gene therapy for haemophilia B approved

Pharma Times

Boost for effected patients as HEMGENIX receives green light from European Commission

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Navigating Payroll Compliance: Future-Proofing Payroll in an Evolving Regulatory Landscape

Speaker: Jennifer Hill

Payroll compliance is a cornerstone of business success, yet for small and midsize businesses, it’s becoming increasingly challenging to navigate the ever-evolving landscape of federal, state, and local regulations. Mistakes can lead to costly penalties and operational disruptions, making it essential to adopt advanced solutions that ensure accuracy and efficiency.

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Virtual reality training in pharma: just a headset away?

European Pharmaceutical Review

The COVID-19 pandemic led to an unparalleled paradigm shift in the use of and the incorporation of new technologies into our workflows. This was particularly apparent in academia and the pharmaceutical industry, where we have seen words such as Teams and Zoom becoming part of our new lexicon of language for meetings. Now we reach for these types of online meetings without a second thought, due to the clear productivity benefits they provide over real in-person meetings. 1 However, notwithstandin

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Current treatments for cramps aren’t cutting it. Why aren’t there better options?

STAT

One day last fall, Kiran’s period cramps became so painful they woke her up from a nap. The 19-year-old took some ibuprofen, but found little relief. “The pain was so bad, it felt like someone was punching me,” said Kiran, who asked to be referred to by only her first name for privacy. It felt “like I was giving birth.

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Brian Fox is bringing ‘fresh eyes’ to ad agency Klick

PharmaVoice

Why the recently appointed president of commercial solutions sees near limitless potential to expand Klick’s footprint across the life sciences — and how generative AI is playing a role.

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SAEM Clinical Images Series: A Rare Cause of Post-traumatic Neck Pain

ALiEM - Pharm Pearls

A 15-year-old male presents to the pediatric Emergency Department (ED) for evaluation of neck pain for three weeks. The patient is vague as to the development of his symptoms, but his mother reveals patient was assaulted by peers three weeks ago and has had progressively worsening neck pain and stiffness. The patient states symptoms have gotten to the point where he is unable to turn his head but denies fevers, chills, nausea, vomiting, focal weakness, or sensory changes.

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Trio of COVID-19 treatments receive NICE nod

Pharma Times

Final draft guidance from NICE ensures people at highest risk will have access to COVID-19 therapies

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From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

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Medicinal cannabis: the route to good manufacturing practice registration

European Pharmaceutical Review

The UK medicinal cannabis sector has witnessed important regulatory advances in recent years. After the substance became legal in the UK in 2018, pharmaceutical companies have faced numerous obstacles to attain a fairer position in the industry. Crucially, January 2023 marked a key moment: the Medicines and Healthcare products Regulatory Agency (MHRA) granted Celadon Pharmaceuticals the first good manufacturing practice (GMP) registration since legalisation in 2018 for high Δ9-tetrahydrocannabin

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Black History Month: Pharmacy Trailblazers

Pharmacy Is Right For Me

February marks Black History Month in the United States. We want to take this opportunity to recognize some Black pharmacists who have made significant contributions to the pharmacy field. James McCune Smith James McCune Smith was born into slavery in 1813. He earned his medical degree from Glasgow University. He is recognized as the first African American to earn a medical degree, the first to be published in American medical journals, as well as the first African American to own and operate a

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Opinion: Disruptive science is leaping forward, not limping along

STAT

A recent study and accompanying news story in the preeminent journal Nature provocatively concludes that disruptive innovation in science has dramatically and mysteriously declined 90% since 1945. The study has prompted a wave of news coverage and tweets decrying the apparent languishing of modern science. We feel that the authors make interesting observations on publishing trends, but their conclusions seem to be quite disconnected from the valuable and transformative innovations that benefit h

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Multimillion-dollar therapies are changing how payers foot the bill

PharmaVoice

With more gene therapies headed to market, novel payment methods are emerging from regulators and academia.

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Why Every Small Business Needs an HCM Solution: A Comprehensive Guide

Managing HR tasks like payroll, compliance, and employee data can overwhelm small businesses. That’s where a Human Capital Management (HCM) solution comes in. Our eBook, Why Every Small Business Needs an HCM Solution: A Comprehensive Guide , shows how an HCM system automates tedious processes, ensuring your business stays compliant and efficient. You’ll learn how to simplify payroll, eliminate costly errors, and empower your employees with self-service tools.

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ACMT Toxicology Visual Pearl: Swollen Lips

ALiEM - Pharm Pearls

Photo used with permission The following physical finding would be most consistent with exposure to which of the following? Bee sting Household bleach Isopropyl alcohol Potassium hydroxide Reveal the Answer Answer 4 – Potassium hydroxide Background The markedly swollen lips and drooling in this photo are seen following a caustic ingestion. Potassium hydroxide, also known as potash, is a caustic substance found in fertilizers, cleaning supplies, and some hair products.

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Sangamo’s ST-920 demonstrates evidence of clinical benefit

Pharma Times

Phase 1/2 research shows that treatment could be very effective against Fabry disease

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First successful CAR-T treatment for muscle inflammation

European Pharmaceutical Review

University Hospital Erlangen in Germany is the first in the world to use chimeric antigen receptor (CAR) T-cells to successfully treat a patient suffering from a severe case of muscle inflammation (myositis). The researchers noted that risk of developing a very severe form of the autoimmune inflammatory disease is high. The patient who received the CAR T treatment was diagnosed with anti-synthetase syndrome.

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Celebrating 40 years of the Orphan Drug Act on Rare Disease Day

PhRMA

For over a decade, Rare Disease Day has been celebrated on February 28 to raise awareness and generate change for the more than 30 million patients in the U.S. living with a rare disease. This year’s Rare Disease Day is particularly special because this year also marks the 40 th anniversary of the Orphan Drug Act (ODA), allowing us to celebrate all the progress that’s come to patients because of it.

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Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

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Opinion: The haunting brain science of long Covid

STAT

Matt Fitzgerald used to bike up and down 3,500 feet through the Santa Ana Mountains on three-hour rides just for fun. Now, nine months after being infected with SARS-CoV-2, the virus that causes Covid-19, he can’t muster walking on flat surfaces for 20 minutes without days of exhaustion. “My long Covid life remains terrifying,” he told me.

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Tapping into the molecular fountain of youth

PharmaVoice

Kristen Fortney, CEO of BioAge Labs, wants to improve the human life span by focusing on the human health span.

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SAEM Clinical Images Series: Hey Doc, Can You Come Look at This Urine?

ALiEM - Pharm Pearls

A 4-year-old male with no significant past medical history presents as a transfer from an outside hospital for suspected inhalation burn secondary to a house fire. The patient was home with his father and sibling when the apartment caught fire from a suspected flame in the kitchen. The patient was evacuated from the building by fire rescue after an unknown period of time.

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Pfizer update Lyme disease vaccine candidate

Pharma Times

Research concerning candidate VLA15 has been discontinued across certain trial sites

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Best Practices to Streamline Compensation Management: A Foundation for Growth

Speaker: Joe Sharpe and James Carlson

Payroll optimization can be one of the most time-consuming and complex factors of small business management. Yet, organizations that crack the code on streamlining employee compensation often discover innovative avenues for growth. With the right strategies in place, outsourcing and streamlining payroll processes can result in substantial time and resource savings.

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Weight loss jabs to be sold via high street chemists in England

The Guardian - Pharmaceutical Industry

Appetite suppressant Wegovy, popular with celebrities, seen as breakthrough treatment but not permanent remedy Weekly weight-loss jabs that are popular with celebrities will soon be made available through high street chemists in England, despite controversy over their use. Many people struggle to tackle obesity through diet and exercise alone as they often find they regain the weight that they lose.

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What they are saying: Nonprofit hospitals are gaming the system at the expense of patients

PhRMA

There have been some alarming stories uncovered by the media on ways nonprofit hospitals — many of which participate in the 340B drug pricing program — are taking advantage of the system and their tax-exempt status to boost their bottom lines, at the expense of patients.

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STAT+: CRISPR pioneer Feng Zhang launches new genetic delivery startup with $193 million

STAT

Akin Akinc was scouring his email spam box last summer, looking for a missing message, when he stumbled across an unexpected email from a quite recognizable name: Feng Zhang. Zhang, one of the leading scientists in the groundbreaking field of genetic editing, had reached out two days prior to discuss a new company he was working on. Since helping to discover CRISPR-Cas9 — often referred to as molecular scissors that can cut into the genome and edit DNA — Zhang has founded at least

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Pheast’s new CEO on how its ‘don’t eat me’ platform could deliver next-gen precision immunotherapies

PharmaVoice

Jacopo Leonardi’s latest venture is in the burgeoning field of macrophage inhibitors that could target a wide range of cancers.

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Enhance Healthcare Efficiency With Top Payroll & HCM Services

Running a healthcare facility requires precision and care, not just for patients but also for your staff. Our guide, "A Buyer’s Guide to Payroll & HCM Services," helps healthcare providers choose the best provider. Efficient payroll management ensures timely, accurate payments, critical for maintaining staff morale and trust. Compliance support helps navigate complex healthcare regulations and avoid costly fines.