Wed.Jul 03, 2024

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‘Visionary’ study finds inflammation, evidence of Covid virus years after infection

STAT

Remember when we thought Covid was a two-week illness? So does Michael Peluso, assistant professor of medicine at the University of California, San Francisco.  He recalls the rush to study acute Covid infection, and the crush of resulting papers. But Peluso, an HIV researcher, knew what his team excelled at: following people over the long term.

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In the rapidly shrinking COVID market, this company still sees opportunity

PharmaVoice

GeoVax is developing a next-gen COVID vaccine targeting a population that’s so far been elusive: immunocompromised patients.

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Study links Ozempic to higher risk of eye condition that can cause vision loss

STAT

A new observational study on Wednesday reported for the first time a potential link between Novo Nordisk’s GLP-1 drugs Ozempic and Wegovy and an eye condition that can cause vision loss. After hearing anecdotes of patients on the diabetes and obesity drugs experiencing nonarteritic anterior ischemic optic neuropathy, or NAION, researchers at Massachusetts Eye and Ear analyzed data from a registry of patients at their institution to see if there was a broad trend.

Diabetes 360
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DP World Mundra welcomes the maiden call of South East Asia-Western India-Middle East service

Express Pharma

DP World, a global provider of smart end-to-end supply chain solutions, welcomed the inaugural voyage of a new weekly mainline service, connecting South East Asia, India and Middle East at DP World Mundra. Marked by successful berthing of MV. ESL vessel, the service strengthens connectivity between key ports in Southeast Asia, India, and the Middle East, reaffirming DP World’s commitment to enhancing global trade.

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Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

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As bird flu spreads among U.S. cattle, veterinarians find themselves in a familiar position: the frontlines

STAT

When, in April, the federal government began requiring some cows to be tested for a strain of avian flu before their herds could be moved across state lines, it seemed like an obvious step to try to track and slow the virus that had started spreading among U.S. dairy cattle. But Joe Armstrong, a veterinarian at the University of Minnesota extension school, feared the U.S.

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5 FDA decisions to watch in the third quarter

BioPharma Dive

Multibillion-dollar buyouts from Bristol Myers Squibb and Gilead could yield new drugs for brain and liver diseases, while a new cell therapy may reach market.

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More Trending

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Dr Vinod P Shah inaugurated the new formulation development Lab at Ortiv-Q3, A Sotax Joint venture company at Ahmedabad on June 30, 2024

Express Pharma

On June 30, 2024, Dr Vinod P. Shah, a former US FDA official and Pharmaceutical Consultant, inaugurated the new Ortiv Q3 Formulation Development Lab in Ahmedabad, alongside, Dr L. Ramaswamy, Chairman & Managing Director of Sotax India, and members of the Board of Directors of Ortiv Q3. The ceremony was graciously attended by distinguished international luminaries like Dr Nikkoletta Fottaki from university of Bath.

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GSK buys mRNA-based Covid, flu vaccines from CureVac in restructured partnership

STAT

GSK and CureVac have restructured an ongoing partnership that gives the British pharma giant control over the development of experimental mRNA-based Covid and flu vaccines, the companies said Wednesday. CureVac, the German biotech that focuses on mRNA vaccines, will receive an initial payment of €400 million upfront ($430 million) from GSK, and is eligible for another €1.05 billion ($1.1 billion) in future payments if certain milestones are hit.

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Discover Vitamin B12 Types | An Essential Nutrient For Health

Welltopia Pharmacy

Vitamin B12 types are crucial for understanding how this nutrient impacts our health and how to choose the best form for supplementation. Vitamin B12, also known as cobalamin, is a crucial water-soluble vitamin that plays a vital role in various bodily functions. It is essential for DNA synthesis, red blood cell formation, and neurological function.

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Opinion: Listen: Why is eugenics still alive and well in scientific publishing?

STAT

While the bogus science of eugenics — the idea that the human race can be improved through selective reproduction — has been nearly universally discredited, remnants of this belief system are still alive and well in modern research. One of the most glaring examples of this is the work of academic psychologist Richard Lynn. Lynn’s work focused on researching human intelligence and the “national IQ” database he compiled on IQ scores from many countries has been c

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5 Reasons to Upgrade Your Pharmacy Management Software

Are you still using workarounds to manage your daily operations? To achieve peak performance, it's time to explore other options for specialty and infusion pharmacy software. Streamline pharmacy operations and improve clinical performance with automated processing, real-time data exchange, and electronic decision support. Download this helpful infographic to: Drive efficiency and patient adherence from referral receipt to delivery and ongoing care – all with our Pharmacy Cloud.

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CPE looking to secure ongoing Pharmacy First funding in core contract

The Pharmacist

The community pharmacy negotiator is looking to ensure that Pharmacy First funding is included within the contractual framework and uplifted for inflation, an increase in activity and service expansion. Janet Morrison, chief executive of Community Pharmacy England (CPE), described the service as ‘strategically significant’, a ‘success’, and the biggest investment in the sector for 10 […] The post CPE looking to secure ongoing Pharmacy First funding in core contract appeared first on The Ph

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STAT+: Pharmalittle: We’re reading about a GSK vaccine deal, an Alzheimer’s drug approval, and more

STAT

Top of the morning to you, and a fine one it is. The skies are clear, the sun is shining, and all sorts of birds are chirping outside our window. Moreover, there is a one-day break tomorrow on this side of the pond due to a holiday. So to celebrate, yes, we are firing up the coffee kettle to indulge in another cup of stimulation. Our choice today is maple bourbon.

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CPHI to return to Messe Frankfurt in 2025

Express Pharma

CPHI Europe, reportedly, the world’s largest pharmaceutical event, will return to Messe Frankfurt from October 28-30, 2025. The event will gather the entire supply chain, including ingredients, finished dosages, machinery, bio, and packaging. The exhibition will feature over 2,400 exhibitors and more than 62,000 attendees from 170 countries. CPHI events highlight industry trends, with analysts predicting growth in 2025.

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STAT+: New Medicare Advantage star ratings give extra bonuses to multiple insurers

STAT

More than two dozen Medicare Advantage insurers received higher quality marks for 2024, based on a STAT review of new data released July 2 by the federal government. Ten health insurance companies, including UnitedHealth Group’s UnitedHealthcare and CVS Health’s Aetna, received critical upgrades in some of their offerings that will allow them to earn hundreds of millions of dollars in extra taxpayer-funded bonuses.

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Constipation Polypharmacy

Med Ed 101

JE is a 77-year-old male. He reports significant constipation despite the use of three laxative medications. In this case summary, I will outline the most important medications that can contribute to constipation polypharmacy. Past medical history includes: The current constipation medications he is taking include: Other medications include: Constipation Polypharmacy Review The first thing I […] The post Constipation Polypharmacy appeared first on Med Ed 101.

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STAT+: What’s next for Cassava Sciences, and Cartesian Therapeutics has a novel excuse for dodgy data

STAT

This is the online edition of Adam’s Biotech Scorecard, a subscriber-only newsletter. STAT+ subscribers can sign up  here to get it delivered to their inbox. Taking time off is nice, but returning for a July 4-shortened workweek is a bit discombobulating. Speaking of which, I’m landing in your inbox a day early because of the holiday.

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Lilly gets FDA OK for Alzheimer’s drug, cites cost advantage

pharmaphorum

Eli Lilly finally has FDA approval for its amyloid-busting Alzheimer’s disease therapy donanemab and will launch it at a cost it claims could deliver savings compared to a rival therapy from Eisai/Biogen.

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STAT+: Regulating artificial intelligence doesn’t have to be complicated, some experts say

STAT

Artificial intelligence has the potential to revolutionize how drugs are discovered and change how hospitals deliver care to patients. But AI also comes with the risk of irreparable harm and perpetuating historic inequities. Would-be health care AI regulators have been spinning in circles trying to figure out how to use AI safely. Industry bodies, investors, Congress, and federal agencies are unable to agree on which voluntary AI validation frameworks will help ensure that patients are safe.

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Beacon lights up with $170m for retinal disease gene therapy

pharmaphorum

Beacon Therapeutics raises $170m for a pivotal trial of its gene therapy for X-linked retinitis pigmentosa, an inherited cause of blindness

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Study reveals cardiovascular health could be biggest risk factor for dementia

Pharma Times

Dementias, including Alzheimer’s disease, are estimated to affect 944,000 people in the UK

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GSK goes all-in on CureVac’s mRNA vaccines

pharmaphorum

GSK has upgraded its longstanding alliance with CureVac on mRNA-based vaccines for respiratory infections, paying €400 million ($429 million) upfront for global rights to its influenza and COVID-19 jabs.

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Study finds headache drug could prevent overuse of acute migraine medications

Pharma Times

Chronic migraine is a neurological condition estimated to affect up to 2.

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EU first to approve Dupixent for COPD

pharmaphorum

EU is first to approve Sanofi and Regeneron's Dupixent for COPD, ending a 10-year hiatus in new therapies

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Poll highlights public attention on pharmacy closures

The Pharmacist

Nearly one in five (18%) UK adults have seen at least one local pharmacy shut in the last twelve months, according to a recent survey by the National Pharmacy Association (NPA) and YouGov. And 6% said they had seen more than one pharmacy close locally. In the online poll of 2,183 UK adults surveyed between […] The post Poll highlights public attention on pharmacy closures appeared first on The Pharmacist.

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Left in limbo: When pharma halts rare disease research

Pharmaceutical Technology

Academic institutions and nonprofit organisations are jumping in to save access to complex gene therapies.

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NHSE: 'Odd' for GPs to turn off pharmacy update record

The Pharmacist

No 'imminent changes' are being made to prevent GP practices from turning off the functionality to allow pharmacies to send structured updates to patient records, NHS England (NHSE)'s director of primary care has said. But she commented that it would be 'odd' for any GP to choose to turn this service off as this would […] The post NHSE: 'Odd' for GPs to turn off pharmacy update record appeared first on The Pharmacist.

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GSK and CureVac to restructure collaboration into new licensing agreement

World Pharma News

GSK plc (LSE/NYSE: GSK) and CureVac N.V. (Nasdaq: CVAC) today announced they have restructured their existing collaboration into a new licensing agreement, allowing each company to prioritise investment and focus their respective mRNA development activities. Since 2020, GSK and CureVac have worked together to develop mRNA vaccines for infectious diseases.

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Eli Lilly’s Kisunla approved by FDA for Alzheimer’s treatment

Pharmafile

Eli Lilly has announced that the US Food and Drug Administration (FDA) has approved Kisunla (donanemab-azbt, 350mg/20ml once-monthly injection for IV infusion) for the treatment of adult patients with early symptomatic Alzheimer’s disease (AD). The post Eli Lilly’s Kisunla approved by FDA for Alzheimer’s treatment appeared first on Pharmafile.

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Advantage J&J in multiple myeloma CAR-T tussle with BMS

pharmaphorum

J&J’s multiple myeloma CAR-T Carvykti improves survival when used as a second-line or later therapy, raising the pressure on BMS’ rival Abecma

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GSK and CureVac to restructure collaboration into licensing agreement

Pharmafile

GSK and CureVac have announced that they have restructured their existing collaboration into a license agreement, which is intended to allow both companies to prioritise investment and focus their respective mRNA development programmes. The post GSK and CureVac to restructure collaboration into licensing agreement appeared first on Pharmafile.

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Frontiers Health 2024: The foundational pillars

pharmaphorum

Frontiers Health, a prominent event in health innovation, has unveiled the foundational pillars that will define its legacy and future trajectory. The announcement of these pillars precedes their global conference, scheduled for the 17th and 18th of October in Berlin.

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CureVac cuts jobs, licenses out vaccines to GSK

BioPharma Dive

The mRNA specialist plans to eliminate 30% of its workforce as part of a restructuring that will prioritize “high-value” projects like its cancer vaccines.

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New tentative approval for Alembic drug dabigatran etexilate mesylate

Drug Patent Watch

Dabigatran etexilate mesylate is the generic ingredient in two branded drugs marketed by Alkem Labs Ltd, Apotex, Hetero Labs Ltd Iii, and Boehringer Ingelheim and, and is included in five NDAs.

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FDA grants fast track status for Full-Life’s prostate cancer treatment

Pharmaceutical Business Review

A lead radiopharmaceutical of the company, 225 Ac-FL-020 acts on prostate-specific membrane antigen (PSMA). The fast track programme of the FDA aims to expedite the development and regulatory review of innovative treatments for serious ailments with unmet medical needs. mCRPC is a condition with limited effective treatments. 225 Ac-FL-020 uses alpha-radiotherapy to specifically attack cancer cells, minimising damage to healthy tissues.

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New patent for Janssen Biotech drug AKEEGA

Drug Patent Watch

Annual Drug Patent Expirations for AKEEGA Akeega is a drug marketed by Janssen Biotech and is included in one NDA. It is available from one supplier. There are eight patents protecting this drug.

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