Fri.Dec 22, 2023

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STAT+: AAFP’s CEO on how to keep primary care doctors in the field

STAT

In ten years, the United States could be short as many as 48,000 primary care doctors. The specialty is underpaid, to a point that doctors are lobbying Medicare to pay it extra. Even medical residents who chose the specialty are leaving primary care ; some 45% of residents who planned to be generalists changed their mind during their residencies. But R.

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As ALS research booms, one treatment center finds itself in the spotlight

PharmaVoice

The Healey center is at the front of ALS research and care, earning acclaim from patients, doctors and scientists. Still, the complexities of the disease and of drug development have brought hard-felt losses.

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Opinion: The unique pain and joy of celebrating Christmas with a child in the pediatric intensive care unit

STAT

In the days leading up to Christmas in the pediatric intensive care unit (PICU), medical teams work to send as many children home as they can. Kids should be with their people for the holidays. And it makes sense. But for parents of children receiving in-home care — parents like me — it can be a relief to surrender to the hospital’s siren song.

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SAEM Clinical Images Series: Enigmatic Traumatic Hip Pain

ALiEM - Pharm Pearls

An 84-year-old female presented with a chief complaint of right hip pain after a fall 12 hours prior to presentation. The patient reported a history of falls resulting in shoulder, rib, and left hip fractures in the past. The patient stated that upon getting out of bed, she took 4-5 steps, lost her balance, and fell backward onto the bedroom floor. She denied loss of consciousness.

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From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

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3 issues to watch in global health in 2024

STAT

As we enter the fifth year of this challenging decade, life finally appears to be inching toward normal — a new normal — on the infectious diseases front. Humans and the SARS-CoV-2 virus seem to be making progress toward a detente with each other. Covid is still a major disruptor, a significant cause of illness and death. But the massive disease waves of the early 2020s have calmed down.

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Federal Court Enters Consent Decree Against Pharmasol for Distributing Adulterated Drugs

LifeProNow

December 14, 2023: “The U.S. District Court for the District of Massachusetts has entered a consent decree of permanent injunction ordering Pharmasol Corporation, a Massachusetts-based company, and President Marc L. Badia to stop distributing drugs until the company complies with the Federal Food, Drug, and Cosmetic (FD&C) Act and other requirements listed in the consent decree.

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GSK enters exclusive license agreement with Hansoh for HS-20093

LifeProNow

December 20, 2023: “GSK plc and Hansoh Pharma, a Chinese biopharmaceutical company committed to discovering and developing life-changing medicines to help patients conquer serious diseases and disorders” announced that they have entered into an exclusive license agreement for HS-20093, a B7-H3 targeted antibody-drug conjugate (ADC) utilising a clinically validated topoisomerase inhibitor (TOPOi) payload.

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STAT+: Venture capital is still pouring into drug research despite Medicare price negotiation

STAT

WASHINGTON — Venture capitalists are still pouring money into drug research in spite of Medicare’s new power to negotiate drug prices, according to Congress’ nonpartisan budget experts. The Inflation Reduction Act includes two measures that directly lower drug prices. Medicare price negotiation is the most controversial of the two.

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10 of our most read articles in 2023

PharmaVoice

A presidential candidate, a changing biotech market and an enduring murder mystery — here are PharmaVoice’s most-read articles this year.

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STAT+: FDA alters warning label for Carvykti CAR-T, although link to secondary cancers is unclear

STAT

The Food and Drug Administration issued a change to the warning label for Legend Biotech and Janssen’s myeloma CAR-T, Carvykti or cilta-cel, adding that some secondary blood cancers have occurred following treatment for multiple myeloma with the cell therapy.  While the label means that physicians will have to have a conversation about secondary malignancies occurring after Carvykti treatment, oncologists and CAR-T experts said the label update won’t change anything about the

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Why Every Small Business Needs an HCM Solution: A Comprehensive Guide

Managing HR tasks like payroll, compliance, and employee data can overwhelm small businesses. That’s where a Human Capital Management (HCM) solution comes in. Our eBook, Why Every Small Business Needs an HCM Solution: A Comprehensive Guide , shows how an HCM system automates tedious processes, ensuring your business stays compliant and efficient. You’ll learn how to simplify payroll, eliminate costly errors, and empower your employees with self-service tools.

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Sanofi stops development of lung cancer drug

European Pharmaceutical Review

French pharmaceutical giant Sanofi announced that it is ending the development programme evaluating tusamitamab ravtansine as a monotherapy for certain patients with metastatic non-squamous, non-small cell lung cancer (NSCLC). The decision comes after interim analysis from a Phase III clinical trial , CARMEN-LC03, did not meet a primary end point. CARMEN-LC03, a randomised, open-label study was evaluating tusamitamab ravtansine as monotherapy compared to docetaxel in patients with metastatic non

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STAT+: Pharmalittle: Bristol Myers to buy schizophrenia-drug maker; Servier found guilty of fraud

STAT

And so, another working week will soon come to a close. Not a moment too soon, yes? This is, you may recall, our treasured signal to daydream about weekend plans. Our agenda is still shaping up, but we expect to promenade with the official mascots, catch up on our reading, and hang with a relative or two. We also hope to hold another listening party with Mrs.

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The Transformative Potential of AI and Machine Learning in Biomedical Research and Healthcare

PharmExec

Oxford Academic report explores the positive improvements these technological capabilities could bring to the industry.

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The clock is ticking, and Cytokinetics is running out of December

STAT

Want to stay on top of the science and politics driving biotech today?  Sign up  to get our biotech newsletter in your inbox. Hello, everyone. Damian here with the final edition of this newsletter for 2023. We’re taking a break for the holidays and will be back in your inbox bright and early on Jan. 3.

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Best Practices to Streamline Compensation Management: A Foundation for Growth

Speaker: Joe Sharpe and James Carlson

Payroll optimization can be one of the most time-consuming and complex factors of small business management. Yet, organizations that crack the code on streamlining employee compensation often discover innovative avenues for growth. With the right strategies in place, outsourcing and streamlining payroll processes can result in substantial time and resource savings.

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A look back at 2023: Smith + Nephew

pharmaphorum

This year brought about a whole gambit of news and developments, of conferences and launches, all coming in thick and fast and excited about the pharmaceutical industry and healthcare system. Not least of these was Smith + Nephew’s opening of a new state-of-the-art surgical innovation and training centre in the heart of Munich, Germany, on 11th October.

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Morning Rounds: Our newsroom’s favorite stories of 2023

STAT

Understand how science, health policy, and medicine shape the world everyday. Sign up for our Morning Rounds newsletter  here. Health data breaches set a record this year “We’re writing to inform you of a cybersecurity incident”: If you’ve gotten a message like this from your health care organization, you’re not alone.

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BMS strikes $14bn deal for Karuna Therapeutics

European Pharmaceutical Review

Bristol Myers Squibb (BMS) has agreed to acquire Karuna Therapeutics for a total of $14.0 billion, strengthening its neuroscience portfolio. Under the terms of the deal, BMS will acquire all outstanding shares of Karuna Therapeutics common stock for $330.00 per share in cash. This represents a 53 percent premium on Karuna’s closing stock price on 21 December 2023.

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Vibrating pill may give dieters a feeling of fullness, study suggests

The Guardian - Pharmaceutical Industry

Research carried out on pigs showed they ate almost 40% less food after ingesting the capsule Dieters everywhere know that, no matter how inventive a chef you may be, nothing leaves you buzzing like sugary or fatty food. Now science might have the answer: a vibrating pill, swallowed before eating, that creates feelings of fullness. Continue reading.

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Enhance Healthcare Efficiency With Top Payroll & HCM Services

Running a healthcare facility requires precision and care, not just for patients but also for your staff. Our guide, "A Buyer’s Guide to Payroll & HCM Services," helps healthcare providers choose the best provider. Efficient payroll management ensures timely, accurate payments, critical for maintaining staff morale and trust. Compliance support helps navigate complex healthcare regulations and avoid costly fines.

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MeiraGTx sells XLRP gene therapy to Janssen

European Pharmaceutical Review

MeiraGTx has entered into an asset purchase agreement with Janssen Pharmaceuticals for the remaining interests in botaretigene sparoparvovec (bota-vec) a gene therapy for the treatment of X-linked retinitis pigmentosa (XLRP). Under the agreement, MeiraGTx is to receive $130 million in upfront and near-term milestone payments. The company will receive up to an additional $285 million in cash payments upon first commercial sales of bota-vec in the US and EU, as well as for manufacturing technology

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2023 in review: Cancer vaccines dose up on advances with tailored approaches 

Pharmaceutical Technology

As the number of patients with cancers continues to grow globally, research into personalised cancer vaccines is vital.

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FDA approves Ionis, AZ’s Wainua for ATTR polyneuropathy

pharmaphorum

AstraZeneca and Ionis get first approval for ATTR polyneuropathy drug Wainua (eplontersen), a rival to drugs from Alnylam and Pfizer

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Lupin launches Softovac Liquifibre

Express Pharma

With this, the company enters the Indian liquid laxative market with this innovative product that is a formulation of Isabgol fibre in liquid form and natural actives such as Sonamukhi, Harad, Mulethi, Saunf, Amaltas and Gulab Dal LupinLife, the consumer healthcare business of Lupin has announced the launch of Softovac Liquifibre , Ayurvedic liquid laxative.

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Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

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3 ways to make 2024 the year of the patient

pharmaphorum

Discover three key strategies to make 2024 the year of the patient in healthcare. Learn how revolutionising trial design, embracing technology, and breaking down silos can improve patient care and outcomes.

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EMCrit Wee – Zero Warning Resuscitation – Mind of the Resuscitationist

EMCrit Project

Is your mind ready for no preparation critical care? EMCrit Project by Scott Weingart, MD FCCM.

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AI and the human touch: Embracing a symbiotic future

pharmaphorum

Discover how AI is transforming the healthcare industry by automating boring and mundane tasks, allowing healthcare professionals to focus on more interesting and important aspects of patient care.

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Bristol Myers to acquire brain drug developer Karuna for $14B

BioPharma Dive

The deal would hand Bristol Myers, which has newly made neuroscience a therapeutic focus, an experimental treatment for schizophrenia.

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5 Reasons to Upgrade Your Pharmacy Management Software

Are you still using workarounds to manage your daily operations? To achieve peak performance, it's time to explore other options for specialty and infusion pharmacy software. Streamline pharmacy operations and improve clinical performance with automated processing, real-time data exchange, and electronic decision support. Download this helpful infographic to: Drive efficiency and patient adherence from referral receipt to delivery and ongoing care – all with our Pharmacy Cloud.

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Which pharmaceutical drugs have the most drug patents in Cyprus?

Drug Patent Watch

This chart shows the drugs with the most patents in Cyprus. Patents must be filed in each country (or, in some cases regional patent office) where patent protection is desired.… The post Which pharmaceutical drugs have the most drug patents in Cyprus? appeared first on DrugPatentWatch - Make Better Decisions.

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Sarepta tests FDA flexibility with bid to expand Duchenne gene therapy’s approval

BioPharma Dive

The biotech is asking the agency to clear its treatment Elevidys in more patients with the disease, despite a confirmatory trial that missed its main goal.

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New patent expiration for Esperion Theraps drug NEXLIZET

Drug Patent Watch

Annual Drug Patent Expirations for NEXLIZET Nexlizet is a drug marketed by Esperion Theraps Inc and is included in one NDA. It is available from one supplier. There are ten… The post New patent expiration for Esperion Theraps drug NEXLIZET appeared first on DrugPatentWatch - Make Better Decisions.

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SELLAS receives orphan drug designation for PTCL therapy

Pharmaceutical Business Review

Currently, SLS009 is under evaluation in a Phase Ib/II trial for patients with r/r PTCL. The study, which is open-label and single-arm, plans to enrol up to 95 patients to assess the drug’s safety and efficacy. If successful, the results may lead to a registrational study. This PTCL trial is fully funded by GenFleet Therapeutics and is being carried out in China.

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New patent for Ucb Inc drug FINTEPLA

Drug Patent Watch

Annual Drug Patent Expirations for FINTEPLA Fintepla is a drug marketed by Ucb Inc and is included in one NDA. It is available from one supplier. There are twelve patents… The post New patent for Ucb Inc drug FINTEPLA appeared first on DrugPatentWatch - Make Better Decisions.

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