Fri.Nov 01, 2024

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Lawsuit to fix pulse oximeter bias makes progress with device manufacturers

STAT

In 2022, Noha Aboelata noticed something troubling. The founding CEO of a health clinic that serves a predominantly Black and brown population, she realized that the racial biases built in pulse oximeters were hurting her patients in Oakland, California. The devices overestimate blood oxygen in people with darker skin tones, making them appear healthier than they are.

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A sickle cell cure exists. But patients need more than just gene therapy.

PharmaVoice

Almost a year after two historic approvals, Pfizer is pulling a sickle cell disease treatment from the market, and the outlook for patients feels shakier. But there’s still hope in the pipeline.

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STAT+: With new Wegovy data in hand, Novo Nordisk will file for approval in MASH

STAT

Novo Nordisk’s weight loss drug Wegovy helped people with a fatty liver disease called MASH experience improvements in liver scarring and achieve symptom resolution, results the company sees as supporting regulatory approval. After 72 weeks in a Phase 3 trial, 37% of patients on Wegovy experienced an improvement in liver scarring, or fibrosis, with no worsening of their disease.

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SAEM Clinical Images Series: Clot in Transit

ALiEM - Pharm Pearls

A 67-year-old male with a past medical history of CHF, MI, hypertension, and diabetes presented to the ED with complaints of headache, chest pain, and dyspnea for the past four days. He stated that he has been without his medications for the past few months due to cost. He denied any past surgical history. He stated that he primarily presented because he felt like “my blood pressure is high” Additional Images Physical Exam Cardiovascular : Tachycardic, 2+ pedal edema bilaterally Re

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From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

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Opinion: Doctors: To get your patients to share, stop judging them when they do

STAT

If you are a doctor, the odds are that your patients think or do things you don’t agree with. Nearly  half of Americans  believe at least one health-related conspiracy theory,  people routinely lie  to their doctors about how much they drink, and  many  act on health information they find on social media without checking with their doctor first.

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Novo, with new results, to seek approval for obesity drug in MASH

BioPharma Dive

The Phase 3 findings position semaglutide to become the first drug of its kind for the liver disease. But they also confirm GLP-1s aren't a "silver bullet" for MASH, one analyst argued.

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NICE trumpets new standard for health AI evaluations

pharmaphorum

With artificial intelligence technologies for healthcare on the rise, UK health technology assessment (HTA) agency NICE has published an economic evaluation standard that it says will help inform coverage and reimbursement decisions.

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Opinion: STAT+: Precision medicine can’t fulfill its promise without better diagnostics

STAT

It’s been 13 years since  the term “precision medicine” was coined , and its promise — the ability to treat the right patient with the right medicine in the right dose at the right time — remains as compelling as ever. But we haven’t yet fulfilled this promise. Why? In my previous role as head of precision medicine at Novartis, I realized the biggest challenge to making precision medicine a reality was not the development of the medicines themselves

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What does this week's Budget mean for pharmacists in general practice?

The Pharmacist

In the Autumn Budget this week, chancellor Rachel Reeves committed to providing an additional £22.6bn to the ‘day-to-day health budget’ – including £100m to use on upgrades to 200 general practice estates in England. The budget also outlined minimum wage increases which may have a knock-on impact across the board, but are currently unfunded in […] The post What does this week's Budget mean for pharmacists in general practice?

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STAT+: Key senators propose using ‘site-neutral’ pay to boost rural hospitals

STAT

WASHINGTON — The hospital industry has pushed back against Medicare payment reforms for years, arguing that the policies would financially hurt rural hospitals.  Two key senators on Friday released a plan to get around that issue by reinvesting some of the money saved from payment reforms to help rural and safety-net hospitals. Hospitals that keep providing services like trauma centers, labor and delivery units, and burn units would get financial bonuses, too.

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Why Every Small Business Needs an HCM Solution: A Comprehensive Guide

Managing HR tasks like payroll, compliance, and employee data can overwhelm small businesses. That’s where a Human Capital Management (HCM) solution comes in. Our eBook, Why Every Small Business Needs an HCM Solution: A Comprehensive Guide , shows how an HCM system automates tedious processes, ensuring your business stays compliant and efficient. You’ll learn how to simplify payroll, eliminate costly errors, and empower your employees with self-service tools.

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The quest for quality continues

Express Pharma

Quality was once again in the spotlight at two recent industry meets. While regulators kept their sights on raising the compliance bar, industry chiefs pledged adherence to these codes. Not surprisingly, most speakers focused on the importance of trust. At the Indian Pharmaceutical Alliance’s (IPA) virtual 9th Advanced Good Manufacturing Practices (GMP) Workshop Dr Rajeev Raghuvanshi, Drugs Controller General of India, CDSCO, Government of India commented, “At the heart of the pharmaceutic

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A setback for the tau approach to Alzheimer’s

STAT

This story first appeared in The Readout newsletter.  Sign up for The Readout  and receive STAT’s award-winning biotech news delivered straight to your inbox.  Morning! Today, we discuss Madrigal’s impressive launch of its MASH drug Rezdiffra, see psychedelics player Compass Pathways shed 30% of its staff, and more.

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Verastem Oncology submits NDA for ovarian cancer treatment

Pharmaceutical Technology

Verastem Oncology has concluded the rolling submission of a new drug application (NDA) to the US Food and Drug Administration (FDA) for a combination of avutometinib and defactinib for low-grade serous ovarian cancer (LGSOC).

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STAT+: Up and down the ladder: The latest comings and goings

STAT

Hired someone new and exciting? Promoted a rising star? Finally solved that hard-to-fill spot? Share the news with us, and we’ll share it with others. That’s right. Send us your changes, and we’ll find a home for them. Don’t be shy. Everyone wants to know who is coming and going. And here is our regular feature in which we highlight a different person each week.

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Best Practices to Streamline Compensation Management: A Foundation for Growth

Speaker: Joe Sharpe and James Carlson

Payroll optimization can be one of the most time-consuming and complex factors of small business management. Yet, organizations that crack the code on streamlining employee compensation often discover innovative avenues for growth. With the right strategies in place, outsourcing and streamlining payroll processes can result in substantial time and resource savings.

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Lexicon's type 1 diabetes drug voted down by FDA adcomm

pharmaphorum

FDA advisors vote against Lexicon Pharma's type 1 diabetes and chronic kidney disease therapy sotagliflozin ahead of December verdict

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STAT+: Pharmalittle: We’re reading about pharma risks in China, mitigating shortages, and more

STAT

And so, another working week will soon draw to a close. Not a moment too soon, yes? This is, you may recall, our treasured signal to daydream about weekend plans. Our agenda is still shaping up, but will almost certainly include tidying up the Pharmalot grounds, promenading with the official mascots, and catching up on our reading. We also hope to hold another listening party, where the rotation will likely include this , this , this , this and this.

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Towards a healthier, more equitable and innovative Indian healthcare sector

Express Pharma

In the past few years, the Indian government has strengthened its focus and allocation to healthcare. The Union Health Ministry received an allocation of about Rs 90,650 crores in the recent budget of 2024-25, a 12.5 per cent increase over 2023-24. Specific highlights of the budget for the sector include an increase in outlay for research and development and for the Ayushman BharatPradhan Mantri Jan Arogya Yojana (PM-JAY), the government’s universal health coverage scheme, which saw a 10 p

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Report: Medicare Part D Premiums Rise an Average of 11% Nationwide

Pharmaceutical Commerce

Analysis finds that while basic Part D coverage costs have decreased by 4%, mid- and high-tier plans have seen hikes of 4% and 21%, respectively.

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Enhance Healthcare Efficiency With Top Payroll & HCM Services

Running a healthcare facility requires precision and care, not just for patients but also for your staff. Our guide, "A Buyer’s Guide to Payroll & HCM Services," helps healthcare providers choose the best provider. Efficient payroll management ensures timely, accurate payments, critical for maintaining staff morale and trust. Compliance support helps navigate complex healthcare regulations and avoid costly fines.

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Green manufacturing in pharma: Sustainable oligonucleotide production on an industrial scale

Express Pharma

Oligonucleotides are at the forefront of modern medicine and have emerged as powerful tools in treating diseases in recent years. Oligonucleotides – short DNA or RNA molecules that host a range of applications in genetic testing, research, and forensics – have seen a marked growth in significance as therapeutics. As their clinical application widens, methods of production must be robust to ensure demand is met.

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'Budget could lead to simmering tensions between practices and their pharmacists'

The Pharmacist

Katie Collin, partner at healthcare tax and accountancy firm Ramsay Brown LLP, explores the impact of this year's Autumn Budget on GP practices and their pharmacists Rachel Reeves’ first Budget has come and gone, and while I’ll admit it’s not been as catastrophic as some of the speculation hinted at, the chancellor’s decisions will still […] The post 'Budget could lead to simmering tensions between practices and their pharmacists' appeared first on The Pharmacist.

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Top 10 rare disease pharma sees 10.4% rise in therapy start

Outsourcing Pharma

A new case study released by AllazoHealth reveals that a leading rare disease pharmaceutical company achieved a 10.4% increase in therapy initiation, driven by AI-enabled patient outreach and personalized communications.

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The GP Awards shortlist: St Austell Healthcare Group Clinical Pharmacist Team

The Pharmacist

We caught up with the Pharmacist/Pharmacy Team of the Year Award shortlist ahead of this year’s General Practice Awards ceremony to be held on 6 December at the Novotel London West. The St Austell Healthcare Group Clinical Pharmacist Team has established itself as a beacon in patient care within its local area. Over the past […] The post The GP Awards shortlist: St Austell Healthcare Group Clinical Pharmacist Team appeared first on The Pharmacist.

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Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

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2024 PharmaVoice 100s: Cancer Care Visionaries

PharmaVoice

Leaders who envision a world without cancer through oncology innovation.

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How Field Reimbursement Services Help Overcome Coverage Barriers and Improve Patient Outcomes

Drug Channels

Today’s guest post comes from Kimberley Chiang, Vice President of Biopharma Commercial Solutions at CoverMyMeds Kimberley highlghts the crucial roles of field reimbursement managers in removing access and reimbursement barriers. She then identifies the keys to successful implementation of field reimbursement services. To learn more, register for CoverMyMeds' November 13, 2024, webinar: Specialty Therapies & Field Reimbursement Services: Driving Better Outcomes for Brands and Patients.

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PharmaVoice 100s: Cancer Care Visionaries

PharmaVoice

Leaders who envision a world without cancer through oncology innovation.

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Drug Repurposing: Unlocking access to rare solutions

Express Pharma

In the marathon of drug development, where billions of dollars and over a decade of research are the norm, drug repurposing is quietly reshaping the landscape. This approach is particularly beneficial for rare diseases, where the treatment options are woefully limited. For conditions affecting fewer than 200,000 individuals, traditional development is economically daunting and repurposing emerges as a pivotal strategy, offering faster, affordable solutions for conditions that have long been left

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5 Reasons to Upgrade Your Pharmacy Management Software

Are you still using workarounds to manage your daily operations? To achieve peak performance, it's time to explore other options for specialty and infusion pharmacy software. Streamline pharmacy operations and improve clinical performance with automated processing, real-time data exchange, and electronic decision support. Download this helpful infographic to: Drive efficiency and patient adherence from referral receipt to delivery and ongoing care – all with our Pharmacy Cloud.

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Abzena’s advanced drug development showcased at CPHI Milan

Outsourcing Pharma

At CPHI Milan 2024, Abzena showcased its latest innovations in cell line development and ADC manufacturing, featuring the advanced AbZelectPRO platform and ThioBridge linker technology.

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GSK enters agreement to acquire CMG1A46 from Chimagen Biosciences to expand immunology pipeline

World Pharma News

GSK plc (LSE/NYSE: GSK) and Chimagen Biosciences (Chimagen), a privately held biotechnology company, announced an agreement for GSK to acquire CMG1A46, a clinical-stage dual CD19 and CD20-targeted T cell-engager (TCE), from Chimagen for $300 million upfront. GSK plans to develop and commercialise CMG1A46 with a focus on B cell-driven autoimmune diseases, such as systemic lupus erythematosus (SLE) and lupus nephritis (LN), with potential to expand into related autoimmune diseases.

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Regeneron battles Wall Street uncertainty; Madrigal extends fast launch of MASH drug

BioPharma Dive

Regeneron shares continued to decline on growing concerns about Eylea’s future. Elsewhere, new details emerged about Lundbeck’s Longboard buyout and PTC continued a quixotic quest.

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US court upholds Avadel’s narcolepsy drug approval amid exclusivity battle 

Pharmaceutical Technology

The US District Court upholds the FDA’s approval of Avadel’s Lumryz, dismissing Jazz’s challenge over market exclusivity for its own drug.

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Eisai, Biogen eye 2025 approval for Leqembi autoinjector

pharmaphorum

Eisai and Biogen complete their rolling application in the US for a subcutaneous formulation of Alzheimer's disease therapy Leqembi

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