Thu.Jan 30, 2025

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STAT+: Vertex, U.K. reach reimbursement deal for CRISPR-based medicine for sickle cell disease

STAT

LONDON — People in England with sickle cell disease will now be able to access the world’s first CRISPR-based medicine under a pricing and reimbursement agreement reached between U.K. health officials and Vertex Pharmaceuticals.  The deal is notable because the U.K.’s cost-effectiveness watchdog initially raised concerns about the durability of the treatment, called Casgevy, in a preliminary ruling last year, saying it wasn’t yet recommending the therapy.

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Vertex’s non-opioid pain drug gets FDA approval in milestone for company and research

BioPharma Dive

Despite high demand for an option like Journavx, doctors fear the drug’s price could be a major hangup for insurers, potentially limiting patients’ ability to access it.

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Cargo to lay off staff after CAR-T data show safety concerns

STAT

Want to stay on top of the science and politics driving biotech today?  Sign up  to get our biotech newsletter in your inbox. Good morning, today we look at RFK Jr.’s first day of confirmation hearings and the latest biotech news.

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RFK Jr. faces reconciliation of past vaccine statements at Senate HHS hearing

PharmaVoice

“Are you supportive of these onesies?” Sen. Bernie Sanders asked Kennedy, pointing to infant clothing stamped with anti-vaccine slogans — and more from yesterday’s confirmation hearing.

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Navigating Payroll Compliance: Future-Proofing Payroll in an Evolving Regulatory Landscape

Speaker: Jennifer Hill

Payroll compliance is a cornerstone of business success, yet for small and midsize businesses, it’s becoming increasingly challenging to navigate the ever-evolving landscape of federal, state, and local regulations. Mistakes can lead to costly penalties and operational disruptions, making it essential to adopt advanced solutions that ensure accuracy and efficiency.

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What your mouth might say about your stroke risk

STAT

Get your daily dose of health and medicine every weekday with STAT’s free newsletter Morning Rounds.  Sign up here. Good morning! It’s Thursday. Friday eve. Can you believe it?

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Focus on minor ailments risks 'underutilising' pharmacists' skills, warns PDA

The Pharmacist

A focus on using community pharmacies to relieve the burden on primary care could lead to the 'unintended consequence' that pharmacists' unique medicines skills are not utilised, the Pharmacists' Defence Association (PDA) has warned. In a report reflecting on the first year of Pharmacy First in England, the PDA highlighted that providing more clinical services […] The post Focus on minor ailments risks 'underutilising' pharmacists' skills, warns PDA appeared first on The Pha

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How are we doing with Pharmacy First?

The Pharmacist

Its been a year of amazing achievements and significant progress, but Pharmacy First has really only just got started, says Shilpa Shah of Community Pharmacy North East London (CP NEL) A year on, and how are we doing with Pharmacy First? The answer is that its a mixed picture. Some surgeries have embraced this service […] The post How are we doing with Pharmacy First?

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Could an ECG spot people at risk of cognitive decline?

pharmaphorum

UK Biobank study suggests someone's risk of premature ageing or cognitive decline could be predicted using a simple ECG reading supported by an AI

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Weekend demand shows value of Pharmacy First access

The Pharmacist

Pharmacies are seeing 'double' the demand for Pharmacy First consultations on Sundays than would be expected in line with reduced opening hours, a new report from the Company Chemists' Association (CCA) has suggested. The CCA said a 'surprising volume' of weekend consultations demonstrated the value of access to the service out-of-hours. Today marks the one […] The post Weekend demand shows value of Pharmacy First access appeared first on The Pharmacist.

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23andMe considers a sale as cash runs low

BioPharma Dive

The testing company ended last year with $79 million and told investors it will need to raise money to fund its operations and financial commitments.

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From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

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Government keeping GP referrals to Pharmacy First 'under review'

The Pharmacist

The government is aware of reports that some GPs have been unwilling to direct patients to Pharmacy First, and will 'keep it under review', a Lords parliamentary under-secretary for health and social care has said. In a House of Lords debate earlier this week (28 January) Labour peer Baroness Winterton of Doncaster highlighted reports 'that […] The post Government keeping GP referrals to Pharmacy First 'under review' appeared first on The Pharmacist.

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RFK Jr. fumbles Medicare basics during second confirmation hearing

BioPharma Dive

Robert F. Kennedy Jr., nominated to be health secretary, seemed unfamiliar with the particulars of the massive insurance program he'd oversee in exchanges with senators Thursday.

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Analysis: The rise of practice pharmacists

The Pharmacist

An explosion in practice pharmacists has proven fruitful for GP practices across England that have turned to the profession for its expertise and support in medication reviews and patient consultations. And it seems the benefits are reciprocated, with pharmacists among the most content profession within general practice teams and looking to stay long term.

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Metsera, Maze secure combined $415 million in IPOs

BioPharma Dive

The offerings reflect an increase in IPO activity that could continue, as four other biotechs recently outlined plans to go public.

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Why Every Small Business Needs an HCM Solution: A Comprehensive Guide

Managing HR tasks like payroll, compliance, and employee data can overwhelm small businesses. That’s where a Human Capital Management (HCM) solution comes in. Our eBook, Why Every Small Business Needs an HCM Solution: A Comprehensive Guide , shows how an HCM system automates tedious processes, ensuring your business stays compliant and efficient. You’ll learn how to simplify payroll, eliminate costly errors, and empower your employees with self-service tools.

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Industry Outlook 2025: Shifting Political Landscapes

PharmaTech

Pharmaceutical Technology sat down with Adam Sherlock, CEO of Qinecsa, to discuss the changing political landscapes in the US and Europe and how that may affect the bio/pharma industry.

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Christophe Weber, veteran Takeda CEO, to retire next year

BioPharma Dive

Julie Kim, currently Takeda’s U.S. head, will replace Weber in June 2026 and become one of the few female CEOs of a top drugmaker.

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FDA Approves Suzetrigine, New Alternative to Opioids for Acute Pain

Pharmacy Times

The drug is a selective NaV1.8 pain signal inhibitor and is the first new class of medication to treat acute pain in over 20 years.

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Sustainability in Inhalation and Small-Molecule Drugs

PharmaTech

Pharmaceutical Technology spoke with Andy Burns, vice president, MDI Business Development at Kindeva, about how sustainability requirements are impacting contract development and manufacturing organizations, specifically for the development and manufacture of inhalation drugs.

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Best Practices to Streamline Compensation Management: A Foundation for Growth

Speaker: Joe Sharpe and James Carlson

Payroll optimization can be one of the most time-consuming and complex factors of small business management. Yet, organizations that crack the code on streamlining employee compensation often discover innovative avenues for growth. With the right strategies in place, outsourcing and streamlining payroll processes can result in substantial time and resource savings.

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Cargo to drop lead CAR-T therapy, lay off staff after study setback

BioPharma Dive

Safety concerns and disappointing efficacy results have led Cargo to stop testing the treatment, cut 50% of its workforce and evaluate strategic alternatives.

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Harnessing generative AI to treat undruggable diseases

World Pharma News

Biomedical engineers at Duke University have developed an AI-based platform that designs short proteins, termed peptides, capable of binding and destroying previously undruggable disease-causing proteins. Inspired by OpenAIs image generation model, their new algorithm can rapidly prioritize peptides for experimental testing. The work appeared Jan. 22 in the journal Science Advances.

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Digoxin Effectively Reduces Circulating Tumor Cell Clusters in Metastatic Breast Cancer, Study Finds

Pharmacy Times

Digoxen is the active ingredient found in the foxglove plant and is commonly used to treat heart failure.

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Are Staffing Issues Quietly Sabotaging Patient Care?

The Script

Did you know that staffing shortages can potentially sabotage patient care? Our team at Rx relief breaks down some of our top insights.

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Enhance Healthcare Efficiency With Top Payroll & HCM Services

Running a healthcare facility requires precision and care, not just for patients but also for your staff. Our guide, "A Buyer’s Guide to Payroll & HCM Services," helps healthcare providers choose the best provider. Efficient payroll management ensures timely, accurate payments, critical for maintaining staff morale and trust. Compliance support helps navigate complex healthcare regulations and avoid costly fines.

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Zentalis to Cut 40% of Workforce Under Strategic Restructuring Plan

PharmaTech

The reduction is expected to be substantially completed, the San Diego-based company said, in the second quarter of 2025.

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MHRA launches refreshed ILAP to speed up NHS drug access

Pharmaceutical Technology

The pathway allows medicine developers to work with the regulators, the NHS and health technology assessment bodies.

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Dust mite allergy sufferers set for a new NHS treatment

pharmaphorum

ALK-Abello's Acarizax for dust mite allergy should soon be available through the NHS in England, Wales, and Northern Ireland, but not in Scotland.

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Takeda announces appointment of Julie Kim as CEO

Pharmaceutical Technology

Takeda has announced the appointment of Julie Kim as the successor to Christophe Weber, effective from June 2026.

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Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

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Takeda CEO succession confirmed as Weber plans retirement

pharmaphorum

Takeda's long-serving chief executive Christophe Weber has said he will retire next year, after 12 years at the Japanese drugmaker.

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Leveragen and Moonlight Bio unite for T-cell therapy development

Pharmaceutical Technology

Leveragen has announced a strategic partnership with Moonlight Bio, targeting the development of T-cell therapies for challenging cancers.

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Pharma Pulse 1/30/25: Treating Disruptive Symptom’s in Crohn’s Patients, Majority of Americans Support Medicare and Medicaid & more

Pharmaceutical Commerce

The latest news for pharma industry insiders.

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Acellera and Psivant partner for AI-driven drug discovery

Pharmaceutical Technology

Acellera and Psivant have announced a strategic research partnership aimed at developing computational drug discovery approaches.

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5 Reasons to Upgrade Your Pharmacy Management Software

Are you still using workarounds to manage your daily operations? To achieve peak performance, it's time to explore other options for specialty and infusion pharmacy software. Streamline pharmacy operations and improve clinical performance with automated processing, real-time data exchange, and electronic decision support. Download this helpful infographic to: Drive efficiency and patient adherence from referral receipt to delivery and ongoing care – all with our Pharmacy Cloud.