STAT

SEPTEMBER 10, 2024

Novo Nordisk on Tuesday reported that its new obesity pill that targets the amylin hormone led to substantial weight loss in an early study, boosting the company’s pipeline of next-generation candidates that may be more effective than Wegovy. In a Phase 1 trial, a 50-mg dose of the daily pill called amycretin, which activates receptors of both the amylin and GLP-1 hormones, led to 10.4% weight loss at about three months after the start of treatment.

Diabetes 356

Diabetes 356

PharmaVoice

SEPTEMBER 10, 2024

Over the past 10 years, PD1-blocking medicines have transformed cancer care. But the steady expansion of their use has slowed and, despite much trying, pharmaceutical companies have largely failed to top the drugs’ successes.

Pharmaceutical Companies 245

Pharmaceutical Companies Pharmaceutical Companies 245

STAT

SEPTEMBER 10, 2024

Amid calls to expand access to medicines in low- and middle-income countries, a new analysis finds that most of the world’s 20 largest pharmaceutical companies have taken steps to reach patients, but many efforts are yielding decidedly mixed results. On the one hand, 19 companies have established methods for providing treatments to these countries — but only nine of the drugmakers created comprehensive plans.

Pharmaceutical Companies 344

Pharmaceutical Companies Pharmaceutical Companies 344

PharmaVoice

SEPTEMBER 10, 2024

Quality-adjusted life years are an important tool to frame a drug’s cost effectiveness, but they leave out other determinants of health.

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STAT

SEPTEMBER 10, 2024

PROVIDENCE, R.I. — In a cavernous converted chapel at Brown University, physician and data scientist Leo Celi observed from the sidelines as a tableful of high school students passed around a plastic, crocodilian device. The pulse oximeter clamped down on one student’s fingertip: Ninety-seven, he read out loud, before handing it off to the student next to him.

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The Pharmacist

SEPTEMBER 10, 2024

The General Pharmaceutical Council (GPhC) will release a consultation on changes to guidance for online pharmacies 'within the next couple of weeks', chief executive Duncan Rudkin has said. Proposed changes will emphasise the importance of a 'two-way dialogue between patients and prescriber', which may require further interaction beyond an asynchronous questionnaire, Mr Rudkin suggested.

Online Pharmacies 108

Online Pharmacies 108

Pharmaceutical Commerce

SEPTEMBER 10, 2024

A pooled analysis of the SWIFT-1 and SWIFT-2 trials found 54% reduction in exacerbation rates over 52 weeks in patients with severe asthma with type 2 inflammation treated with depemokimab.

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STAT

SEPTEMBER 10, 2024

For months, investors have been asking Roivant Sciences chief executive Matt Gline to reveal the next drug it planned to buy with some of the $6 billion made from last year’s Roche deal. On Tuesday, Gline obliged. Roivant has acquired from Bayer, the German pharma company, an experimental drug called mosliciguat that will be developed as a treatment for certain types of pulmonary hypertension, a family of serious lung diseases in which high blood pressure affects the arteries in the lungs

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Outsourcing Pharma

SEPTEMBER 10, 2024

Creyon Bio Inc., a clinical-stage biotechnology company specializing in AI and machine learning-enabled oligonucleotide-based medicines (OBMs), recently announced the issuance of its second US patent.

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STAT

SEPTEMBER 10, 2024

Two former Verily executives say that they are starting a new initiative, Highlander Health, to push forward an effort decades in the making: making it so that the records collected in hospitals can be used in real-time to advance science, decreasing the cost of conducting clinical trials and speeding medical progress while helping patients get the right drug for them.

Hospitals 309

Hospitals 309

Speaker: Joe Sharpe and James Carlson

In the world of small business management, the challenge of managing payroll & HR efficiently while scaling operations can be overwhelming. Yet, with the right strategies in place, these challenges can become opportunities for growth and innovation. In this session, Joe Sharpe, Senior Director of Managed Payroll Services at IRIS, will reveal practical methods and expert insights for outsourcing and streamlining payroll processes, resulting in substantial time and resource savings.

The Pharmacist

SEPTEMBER 10, 2024

Community Pharmacy England (CPE) is concerned that local pharmacies may walk away from delivering Pharmacy First consultations if they cannot reach the thresholds for the £1,000 monthly payment. Speaking at the Avicenna Heathrow conference this weekend (8 September), CPE's director of NHS services Alastair Buxton said the number of clinical pathway consultations required for the […] The post CPE concerned pharmacies will 'walk away' from Pharmacy First appeared first on The Pharm

Community Pharmacies 106

Community Pharmacies 106

STAT

SEPTEMBER 10, 2024

This is Part 4 of “ Behind the Counter ,” an in-depth video series demystifying the complex world of patents and drug pricing. Years ago, when a brand-name medication’s patent expired, consumers had to wait a long time for a more affordable generic version to come to market. But in 1984, a little-known law put an end to that waiting period and paved the way for the large quantity of generic drugs available today.

Drug Pricing 299

Drug Pricing 299

World Pharma News

SEPTEMBER 10, 2024

Bothnia dystrophy is a form of hereditary blindness, prevalent in the region Västerbotten in Sweden. A new study at Karolinska Institutet published in Nature Communications shows that gene therapy can improve vision in patients with the disease. Bothnia dystrophy occurs mainly in the region Västerbotten in Sweden, but the disease has also been identified in other parts of the world.

Communication 95

Communication 95

STAT

SEPTEMBER 10, 2024

Seven years after the FDA approved Luxterna , scientists have yet to bring another congenital blindness treatment to the market. A team of researchers from the Perelman School of Medicine at the University of Pennsylvania aims to change this. The group recently published a study in The Lancet documenting their success using gene therapy to treat an inherited retinal blindness that affects as many as 100,000 people globally.

Documentation 294

Documentation 294

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Express Pharma

SEPTEMBER 10, 2024

As per GlobalData report, in August 2024, the healthcare sector experienced a notable decrease in deal value. The total deal value dropped by 29.6 per cent compared to August 2023. The industry reported 66 deals worth $7.5 billion, a significant decline from the average of 94 deals worth $18 billion in the previous 12-month period from August 2023 to July 2024.

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STAT

SEPTEMBER 10, 2024

What does it cost to have a baby in the United States? This question has always vexed me. I’ve tried unsuccessfully to prospectively price deliveries for family and friends over the years. After insurance, deliveries can range from a few hundred dollars to a couple of thousand. If you’re underinsured or have a more complex birth, it can cost more than $10,000 out of pocket.

Hospitals 294

Hospitals 294

Express Pharma

SEPTEMBER 10, 2024

Biogetica, known for its integrative approach to medicine, has reinforced its commitment to advancing evidence-based natural treatments in both the Indian and US markets. The company combines supplements, nutraceuticals, herbs, and homoeopathy to address health across all dimensions of human existence. Biogetica’s methods are founded on blending the strengths of different medical systems, ensuring that each product undergoes scientific validation.

Immunity 100

Immunity Immunization 100

STAT

SEPTEMBER 10, 2024

WASHINGTON – Powerful House lawmakers from both parties are skeptical of the Food and Drug Administration’s pitch to start collecting fees from e-cigarette companies, similar to how the agency assesses them on tobacco firms. FDA officials say that the fees, which e-cigarette companies would pay when filing applications with the agency, would give regulators resources to tackle the thousands of illegal vapes lining store shelves.

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Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

Express Pharma

SEPTEMBER 10, 2024

Detailed results from one of AstraZeneca’s key lung cancer trials released recently showed that its experimental precision drug did not significantly improve overall survival results for patients in the trial. The overall survival, or OS rates, in the TROPION-Lung01 trial “did not reach statistical significance”, the company said in a presentation at the World Conference on Lung Cancer in San Diego.

Chemotherapy 98

Chemotherapy 98

STAT

SEPTEMBER 10, 2024

Sanofi and Regeneron’s blockbuster drug Dupixent successfully treated patients with chronic spontaneous urticaria, an inflammatory skin disease, in a late-stage trial, the companies announced on Wednesday, bringing the firms closer to securing Food and Drug Administration approval after the agency rejected their application last year. In the Phase 3 trial, dubbed Liberty-Cupid Study C, patients took antihistamines, the current standard of care, and Dupixent or a placebo.

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Pharmaceutical Technology

SEPTEMBER 10, 2024

Baltimore opted out of a national settlement last year, instead pursuing its own claim against the opioid manufacturer.

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STAT

SEPTEMBER 10, 2024

You’re reading the web edition of STAT’s Health Tech newsletter, our guide to how technology is transforming the life sciences.  Sign up to get it  delivered in your inbox every Tuesday and Thursday. Flare Capital ‘s new examination of 4,000 healthcare AI venture capital deals looked at where investment has actually created value — that is, what early-stage, venture-backed technology matures enough to impact the health care ecosystem?

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Pharmacy Management

PioneerRx

SEPTEMBER 10, 2024

ER prescriptions requires a different kind urgency and attention to detail compared to maintenance medications — so let’s get on the right foot.

Prescription Management 95

Prescription Management 95

STAT

SEPTEMBER 10, 2024

Elevance Health, the parent of more than a dozen state Blue Cross Blue Shield plans, is purchasing Indiana University Health’s insurance business in a deal that would increase its dominance in several key cities in the state. IU Health’s decision to sell is the latest and most prominent example of hospital systems giving up on the idea that they can be both a provider and payer of care.

Health Insurance Companies 269

Health Insurance Companies Hospitals 269

Express Pharma

SEPTEMBER 10, 2024

The market for weight-loss treatments is expected to see 16 new drugs vying for a slice of the lucrative business currently dominated by Novo Nordisk and Eli Lilly, according to estimates from analysts at Morningstar and Pitchbook. In a joint report published on Monday, analysts estimated the market for obesity treatments could expand to $200 billion by 2031.

Diabetes 95

Diabetes Pharmaceutical Companies Pharmaceutical Companies Drug Development 95

STAT

SEPTEMBER 10, 2024

Get your daily dose of health and medicine every weekday with STAT’s free newsletter Morning Rounds.  Sign up here. Hello, happy Tuesday. Temperatures are projected to be in the 50s every morning this week in Boston, per a glance at my phone. Is it officially fall? Where can I get a good apple cider donut? What stories should we report before the end of the year creeps up on us?

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Pharma Times

SEPTEMBER 10, 2024

Molecular imaging agent 99mTc-maraciclatide to aid in disease prognostication

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STAT

SEPTEMBER 10, 2024

Morning! Today, we’ll keep riding the bispecific wave, and tell you what Verily and FDA alum Amy Abernethy is up to next. Oh, and a programming note: The annual ESMO meeting opens this weekend, and we’ve got a pop-up newsletter. Sign up if you’re interested. The need-to-know this morning Roivant Sciences acquired from Bayer , the German pharma company, an experimental drug called mosliciguat that will be developed as a treatment for certain types of pulmonary hypertension, a

Drug Pricing 259

Drug Pricing Drug Development 259

Express Pharma

SEPTEMBER 10, 2024

The migraine market across the seven major markets (7MM*) is forecast to grow from $9.2 billion in 2023 to $16.4 billion by 2033 at a compound annual growth rate (CAGR) of 6.0 per cent, according to GlobalData. GlobalData’s latest report, “Migraine: Seven-Market Drug Forecast and Market Analysis,” reveals that primarily driven by increased prescription of calcitonin gene-related peptide (CGRP) antagonists—monoclonal antibodies (mAbs) for prevention and oral gepants for both acute and preventive

Compounding 83

Compounding 83

STAT

SEPTEMBER 10, 2024

Viridian Therapeutics said Tuesday that an experimental treatment improved the signs and symptoms of thyroid eye disease — results that achieved the primary goals of a Phase 3 clinical trial and compared favorably to a similar drug already approved and sold by Amgen.  In the 15-week study, 70% of participants responded to treatment with Viridian’s drug called VRDN-001, compared to 5% in the placebo group.

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BioPharma Dive

SEPTEMBER 10, 2024

A small, early study produced what one analyst called “highly compelling” results that lifted the company’s shares by as much as 15% Tuesday.

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STAT

SEPTEMBER 10, 2024

Top of the morning to you and a fine one it is. Blue skies, cool breezes and plenty of chirping birds are enveloping the comfy Pharmalot campus, which is cause to fire up the coffee kettle for yet another cup of stimulation. Our choice today is pecan pie — sweets for the sweet, you know. Meanwhile, we have assembled the latest menu of tidbits for you to peruse.

Pharmaceutical Companies 159

Pharmaceutical Companies Pharmaceutical Companies 159