Tue.Jul 09, 2024

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The untold story of the Human Genome Project: How one man’s DNA became a pillar of genetics

STAT

STAT is co-publishing this investigation by Undark. They numbered 20 in all — 10 men and 10 women who came to a sprawling medical campus in downtown Buffalo, N.Y., to volunteer for what a news report had billed as “the world’s biggest science project.

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Could pharma’s blockbuster immunotherapies work in dogs?

PharmaVoice

Vetigenics believes it’s found a way to make pricey antibody-based technologies more accessible for animals.

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Opinion: Everyone deserves addiction treatment that works — including those in jail

STAT

The overdose crisis is claiming lives across the United States, but it reaches new depths of despair in the criminal justice system. Overdose is the leading cause of death among people returning to their communities after being in jail or prison. Providing addiction treatment in these settings could change that. Roughly 60% of people who are incarcerated have a substance use disorder, in many cases an opioid use disorder.

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FDA approval is just the beginning. Now Lilly’s Kisunla faces the tough Alzheimer’s market.

PharmaVoice

Recent history suggests an Alzheimer’s approval doesn’t necessarily translate to market triumph. Perhaps for Eli Lilly’s Kisunla, this time could be different.

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From Payroll Pains to Growth Gains: Streamlining Payroll & HR for Success

Speaker: Joe Sharpe and James Carlson

In the world of small business management, the challenge of managing payroll & HR efficiently while scaling operations can be overwhelming. Yet, with the right strategies in place, these challenges can become opportunities for growth and innovation. In this session, Joe Sharpe, Senior Director of Managed Payroll Services at IRIS, will reveal practical methods and expert insights for outsourcing and streamlining payroll processes, resulting in substantial time and resource savings.

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STAT+: FTC report finds PBMs profit at the expense of patients and independent pharmacies

STAT

In stark terms, the Federal Trade Commission found in a report released Tuesday that pharmacy benefit managers — the opaque middlemen in the pharmaceutical supply chain — wield such “enormous power” that these companies can affect the ability of many Americans to access and afford their medicines. The agency noted that the three largest PBMs processed nearly 80% of the roughly 6.6 billion prescriptions dispensed by U.S. pharmacies in 2023.

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Pfizer research chief Dolsten to step down, with company at a crossroads

BioPharma Dive

The company has begun searching for a successor to Dolsten, who oversaw more than 35 drug and vaccine approvals but also some notable setbacks during his time as Pfizer’s top scientist.

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Discover Vitamin D3 Foods | A Comprehensive Guide

Welltopia Pharmacy

Vitamin D3 Foods play a crucial role in ensuring optimal health by providing a vital nutrient that supports bone strength, immune function, and overall well-being. Vitamin D3, also known as cholecalciferol, is one of the most crucial nutrients for maintaining optimal health.

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STAT+: Mikael Dolsten, Pfizer CSO who could take on Covid but not Wall Street, to step down

STAT

Five years ago — before the pandemic — Pfizer’s head of research and development, Mikael Dolsten, told STAT he kept a chess set in his office that he got as a gift from a former CEO of the company. It was a memento delivered to Dolsten after he cautioned his boss that research and development was a long process, like a chess match, not something that would happen quickly.

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Chromatography analysis for nitrosamine quantitation in pharmaceutical manufacturing water

European Pharmaceutical Review

Researchers have developed an ultrasensitive analytical method for quantifying nitrite quantity in process water for pharmaceutical products. The team tested various samples two ion chromatography analytical methods. This included a range of water types eg, purified and potable water, according to the paper. Kumar et al. explained that “accurate determination of nitrite content in process water will support an understanding of the potential for nitrosamine formation from nitrite in process water

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Lilly’s obesity drug looks more potent than Novo’s in observational study

STAT

Want to stay on top of the science and politics driving biotech today?  Sign up  to get our biotech newsletter in your inbox. Good morning. STAT published an investigation this morning on the untold story of the Human Genome Project and ethics concerns surrounding the ambitious project. Check it out  here.

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Enhance Healthcare Efficiency With Top Payroll & HCM Services

Running a healthcare facility requires precision and care, not just for patients but also for your staff. Our guide, "A Buyer’s Guide to Payroll & HCM Services," helps healthcare providers choose the best provider. Efficient payroll management ensures timely, accurate payments, critical for maintaining staff morale and trust. Compliance support helps navigate complex healthcare regulations and avoid costly fines.

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Francis Crick and ICL spinout raises £90m to clinically develop cancer treatments

Pharma Times

Myricx Bio’s therapies include treatments for breast, lung and colorectal cancer

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Opinion: STAT+: Private equity and neuroscience: a novel approach to developing new treatments for neurological disorders

STAT

Neurological diseases are now the leading cause of poor health and disability worldwide. An estimated 3.4 billion people, or 40% of the world’s population, are affected by neurological disorders such as Alzheimer’s disease and other dementias, stroke, migraine, depression, anxiety, neonatal encephalopathy, and more. Efforts to expand research that can lead to new and more effective treatments for neurological diseases are sorely needed.

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SMC accepts Boehringer/Lilly’s Jardiance for CKD within NHS Scotland

Pharma Times

The serious, progressive kidney disease affects nearly 850 million people worldwide

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A rare voice box transplant helped a cancer patient speak again, part of a pioneering study

STAT

WASHINGTON — A Massachusetts man has regained his voice after surgeons removed his cancerous larynx and, in a pioneering move, replaced it with a donated one. Transplants of the so-called voice box are extremely rare, and normally aren’t an option for people with active cancer. Marty Kedian is only the third person in the U.S. ever to undergo a total larynx transplant – the others, years ago, because of injuries – and one of a handful reported worldwide.

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Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

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How to find low-competition generic drug opportunities

Drug Patent Watch

To find low-competition generic drug opportunities, focus on drugs with limited competition due to small patient populations, complex formulations, or […] Source

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Novo Holdings co-leads £90 million Series A financing for Myricx Bio

Express Pharma

Novo Holdings announces that it has co-led a £90 million ($114 million) Series A financing for Myricx Bio, the largest European biotech Series A financing this year. Myricx Bio is a UK biotech company focusing on the discovery and development of a novel payload class for antibody-drug conjugates (ADCs). The funds will be used to advance Myricx’s proprietary pipeline of N-Myristoyltransferase inhibitor (NMTi) ADCs through clinical proof of concept, targeting clinically validated tumour-associat

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Digital health financing shows signs of recovery in H1

pharmaphorum

After languishing in the doldrums for a few quarters, there are signs that the winds of investment are starting to blow again in the US digital health sector.

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Health and social care ministers appointed

The Pharmacist

The Department of Health and Social Care has confirmed the appointment of two new ministers – one for health and one for social care. Karin Smyth, MP for Bristol South for almost 10 years and previously a non-executive director of a primary care trust, will take on the role as minister of state for health. […] The post Health and social care ministers appointed appeared first on The Pharmacist.

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5 Reasons to Upgrade Your Pharmacy Management Software

Are you still using workarounds to manage your daily operations? To achieve peak performance, it's time to explore other options for specialty and infusion pharmacy software. Streamline pharmacy operations and improve clinical performance with automated processing, real-time data exchange, and electronic decision support. Download this helpful infographic to: Drive efficiency and patient adherence from referral receipt to delivery and ongoing care – all with our Pharmacy Cloud.

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FTC report finds PBM power has “dire consequences”

pharmaphorum

A long-awaited report from the US Federal Trade Commission (FTC) on pharmacy benefit managers (PBMs) is out – and will make uncomfortable reading for the pharma supply chain middlemen.Its central message is clear. The six largest PBMs in the US manage nearly 95% of all prescriptions filled in the US, a “concentrated market structure” that has allowed them to “profit at the expense of patients and independent pharmacists,” according to the financial regulator.

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Lupin gains tentative FDA approval for Empagliflozin, Linagliptin, Metformin Hydrochloride ER tablets

Express Pharma

Lupin announced that it has received tentative approval from the United States Food and Drug Administration for its Abbreviated New Drug Application for Empagliflozin, Linagliptin and Metformin Hydrochloride Extended-Release (ER) Tablets, 5 mg/2.5 mg/1,000 mg, 10 mg/5 mg/1,000 mg, 12.5 mg/2.5 mg/1,000 mg, and 25 mg/5 mg/1,000 mg, to market a generic equivalent of Trijardy XR Extended-Release Tablets, 5 mg/2.5 mg/1,000 mg, 10 mg/5 mg/1,000 mg, 12.5 mg/2.5 mg/1,000 mg, and 25 mg/5 mg/1,000 mg, of

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Unified Patent Court Reshapes European Patent Landscape

Drug Patent Watch

In a seismic shift for European intellectual property, the Unified Patent Court (UPC) is rapidly transforming how businesses approach patent […] Source

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FDA updates guidance to address spread of misinformation

Express Pharma

The US Food and Drug Administration aims to advance its mission of ensuring the public has access to accurate, up-to-date science-based information to inform decisions about FDA-regulated medical products to maintain and improve their health. The agency is providing updated recommendations to empower industry seeking to voluntarily address misinformation about or related to their approved/cleared medical products.

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Opportunity costs of gene therapies. Where do we go from here?

pharmaphorum

Learn about the opportunity costs of gene therapies like Beqvez. Discover the obstacles and potential paths forward in the evolving field of gene therapy.

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J&J receives full approval from US FDA and European Commission for SIRTURO

Express Pharma

Johnson & Johnson announced that the USFood and Drug Administration (FDA) has issued traditional approval for SIRTURO (bedaquiline) as part of combination therapy in adult and pediatric patients (5 years and older and weighing at least 15 kg) with pulmonary tuberculosis (TB) due to Mycobacterium tuberculosis resistant to at least rifampicin and isoniazid.

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Coroner investigates death after 'huge' quantity of drugs bought online

The Pharmacist

A coroner investigating an overdose death has raised ‘grave concerns’ about online drug sales, including the lack of communication with a patient’s GP. The same case suggested failings in communication between hospital and community pharmacy, which the coroner said she was satisfied have since been resolved. 'Huge' quantity of drugs bought online Last month, coroner […] The post Coroner investigates death after 'huge' quantity of drugs bought online appeared first on The Pharmaci

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The impact of biosimilars on biologic drug distribution models

Drug Patent Watch

The introduction of biosimilars has significantly altered the landscape of biologic drug distribution models.

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A spectrum of obesity requires precision

pharmaphorum

In this latest pharmaphorum podcast, web editor Nicole Raleigh speaks with Michael Kyle, chief medical officer at Currax Pharmaceuticals – a company working to advance a greater understanding of how to effectively treat obesity – about perceptions and options beyond the bounds of GLP-1s, including evolution of hypertension treatments.

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After a harrowing summer, will Bengaluru’s water future change?

Express Pharma

Bengaluru recently bore a severe water crisis, and its scars are fresh for those whose lives were upended. From the hush in school corridors to the solemn whispers of hospital wards, from the hurried rituals of crematoriums to the humble routines of household chores, and the fading rumble of factories, the spectre of a city drying out haunts our collective consciousness.

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YSEOP transforms pharma industry with AI-powered solutions for efficient document workflows

Outsourcing Pharma

In an in-depth interview with Liza Laws, Senior Editor of Outsourcing-Pharma (OSP), Tim Martin, a key figure at YSEOP, shared insights on the company's recent advancements and activities in AI and drug discovery, and how their solutions are transforming the pharmaceutical industry.

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Roche will relaunch AMD implant Susvimo after update

pharmaphorum

Roche will reintroduce its Susvimo implant wet AMD, which was withdrawn from sale in 2022 due to manufacturing defects.

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Vector Labs' Pam James - from failed 'experiments' with dad to a doctorate in immunology

Outsourcing Pharma

Her grandmother was in a marching band in the early 1900s and mom was only ond of two in her graduating class as a pharmacist and her dad, an inventor with more than 30 patents.

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UniQure stock surges on data for Huntington’s gene therapy

BioPharma Dive

The biotech’s stock rose more than 60% as fresh data appeared to alleviate some investor concerns about the therapy’s effectiveness and reliability.

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dsm-firmenich launches CBtru, revolutionizing CBD drug development with enhanced bioavailability

Outsourcing Pharma

dsm-firmenich has announced the launch of CBtru â an advanced formulated cannabidiol (CBD) drug product intermediate designed for oral solid delivery formats.