Mon.Jun 03, 2024

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STAT+: Physicians take Medicare Advantage to task for rural patients’ care gaps

STAT

In the rural California town where physician Atashi Mandal sees patients, Medicare Advantage is popular among the older residents, many of whom have multiple chronic health conditions. Problem is, there aren’t any in-network providers for several hundred miles. “My patients seem to be unaware of this major deficiency regarding participation in Medicare Advantage plans,” Mandal wrote in a recent letter to the Centers for Medicare and Medicaid Services.

Hospitals 360
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Merck and Moderna’s cancer vaccine snags a clinical win in a field decades old

PharmaVoice

Cancer vaccines are taking off in the clinic, and a partnership between Merck and Moderna is at the forefront of a new wave of immunotherapy.

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Trending Sources

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STAT+: Elevance PBM’s president out as customers complain of prescription chaos

STAT

Paul Marchetti, the head of insurer Elevance Health’s pharmacy benefit manager, has left the company amid a wave of consumer complaints about patients receiving incorrect medicines or being unable to get their prescriptions filled. Elevance did not confirm Marchetti’s departure as the president of CarelonRx, but according to his Linkedin profile, he left the company in May.

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In an era of big patent losses, drug launches need years of runway

PharmaVoice

Jim Lang, CEO of Eversana, explains the shifting commercial environment and how past drug launch failures are informing the future.

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Navigating Payroll Compliance: Future-Proofing Payroll in an Evolving Regulatory Landscape

Speaker: Jennifer Hill

Payroll compliance is a cornerstone of business success, yet for small and midsize businesses, it’s becoming increasingly challenging to navigate the ever-evolving landscape of federal, state, and local regulations. Mistakes can lead to costly penalties and operational disruptions, making it essential to adopt advanced solutions that ensure accuracy and efficiency.

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Opinion: Antibiotic innovation is ailing. ‘Brain drain’ may kill it

STAT

In today’s labor market, good help is hard to find. For companies developing antibiotics, it’s becoming nearly impossible. Three years ago, I became CEO of the AMR Action Fund , which is investing approximately $1 billion in biotech companies developing treatments for antimicrobial-resistant infections, a growing global health crisis that now contributes to 4.9 million deaths every year.

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Opinion: Shifting the focus from loneliness to social health

STAT

It’s been one year since the U.S. surgeon general issued a national warning about an epidemic of loneliness. Other countries recognized the problem earlier: the United Kingdom appointed a minister for loneliness in 2018; Japan did the same in 2021. These initiatives have brought attention to — and spurred action around — an important problem with serious health consequences, which include increased risks of heart disease, dementia, and premature death.

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International KCL research project to develop SMARTdrugs for aggressive cancers

Pharma Times

The platform will be used to diagnose and treat cancers, including lung and brain tumours

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STAT+: ASCO24: AstraZeneca won cancer’s big meeting — again. Will that help it fulfill its $80 billion ambition?

STAT

CHICAGO — AstraZeneca’s head of cancer research and development, Susan Galbraith , is British, and prone to a particularly British style of understatement. She doesn’t boast loudly. But she did come to this year’s annual meeting of the American Society of Clinical Oncology wearing a small lapel pin with the numeral 6 and the “AZ” corporate logo.

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After two Big Pharma deals, Nimbus looks to keep the hits coming

PharmaVoice

With the billion-dollar-plus deals under its belt with Gilead and Takeda, the biotech’s CEO explains where the company is going next.

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From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

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STAT+: At ASCO, AstraZeneca says its CAR-T therapy shrank solid liver tumors in early trial

STAT

CHICAGO — A next-generation CAR-T therapy was able to substantially shrink tumors in patients with liver cancer in early clinical data presented Monday at the American Society of Clinical Oncology annual meeting. The study, though preliminary and small with only 24 patients, represents a triad of firsts for one of the trial’s sponsors.

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Pharmacogenomics and IVDR: Overcoming transition challenges

pharmaphorum

Understanding the challenges and opportunities in transitioning to IVDR for pharmacogenomics can be complex. Learn more about how to overcome these challenges effectively.

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STAT+: Structure Therapeutics oral GLP-1 drug led to weight loss in two studies

STAT

Structure Therapeutics reported Monday that its oral GLP-1 drug led to weight loss in two small studies, leading shares to surge in pre-market trading. In a 12-week Phase 2a study, the daily pill in a capsule formulation led to 6.2% placebo-adjusted weight loss. In a separate 12-week pharmacokinetics study, the company tested a new tablet formulation of the drug, called GSBR-1290, and it led to placebo-adjusted weight loss of up to 6.9%.

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EMCrit Wee – Controlled Automated Reperfusion of the Whole Body (CARL) ECPR / ECLS Yields Amazing Results

EMCrit Project

Today, we talk about a paper that showed impressive neurologically intact survival for all-rhythms presenting in cardiac arrest, both OHCA and IHCA. It uses a new set of strategies and technologies called CARL. The Paper Treatment of Refractory Cardiac Arrest by Controlled Reperfusion of the Whole Body: A Multicenter, Prospective Observational Study Supplemental Material […] EMCrit Project by Scott Weingart, MD FCCM.

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Why Every Small Business Needs an HCM Solution: A Comprehensive Guide

Managing HR tasks like payroll, compliance, and employee data can overwhelm small businesses. That’s where a Human Capital Management (HCM) solution comes in. Our eBook, Why Every Small Business Needs an HCM Solution: A Comprehensive Guide , shows how an HCM system automates tedious processes, ensuring your business stays compliant and efficient. You’ll learn how to simplify payroll, eliminate costly errors, and empower your employees with self-service tools.

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STAT+: Which hospital systems will join Kaiser’s Risant next?

STAT

More than a year ago, Kaiser Permanente made waves when it said it was creating a new, sprawling entity of nonprofit hospitals and doctors with Geisinger as its first takeover — the latest example of health care companies bulking up in an already highly consolidated industry. Nothing has happened since then, at least publicly. Geisinger’s 10 hospitals and 1,700 employed physicians are now officially part of the group, known as Risant Health.

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ASCO: DREAMM-8 data puts GSK’s Blenrep back on track

pharmaphorum

GSK planning to refile anti-BCMA drug Blenrep in the US for multiple myeloma after reporting positive results from the DREAMM-8 trial at ASCO

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STAT+: Leading CRO to pay record fine for badly neglecting hundreds of beagles in breeding facility

STAT

A leading contract research organization has agreed to pay $35 million — including the largest-ever fine for violating the Animal Welfare Act — as part of a criminal plea for badly neglecting hundreds of beagles in a breeding facility. The investigation into Inotiv, which provides drug discovery and development services to the pharmaceutical industry, drew national attention in May 2022 after U.S.

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ASCO: AstraZeneca’s triple whammy in lung and breast cancer

pharmaphorum

AstraZeneca's ASCO 'super sunday' delivers new data for Tagrisso and Imfinzi in lung cancer and Enhertu in breast cancer

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Best Practices to Streamline Compensation Management: A Foundation for Growth

Speaker: Joe Sharpe and James Carlson

Payroll optimization can be one of the most time-consuming and complex factors of small business management. Yet, organizations that crack the code on streamlining employee compensation often discover innovative avenues for growth. With the right strategies in place, outsourcing and streamlining payroll processes can result in substantial time and resource savings.

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STAT+: Delfi Diagnostics announces key data, study design for its liquid biopsy test

STAT

CHICAGO — Delfi Diagnostics, a company seeking to develop liquid biopsy tests to help screen for lung cancer, published a scientific paper on Monday describing key aspects of the test and unveiled the design of a key clinical trial. Delfi also announced that the Merck Global Health Innovation Fund, the VC arm of the drug giant, has made an investment of an undisclosed amount in the company.

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US-Chinese relations put the brakes on biotech cooperation

pharmaphorum

The BIOSECURE Act is a proposed legislation that reflects the current strained US-Chinese relations, impacting biotech cooperation. Learn more about the implications and challenges.

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STAT+: Becton Dickinson to buy Edwards patient monitoring unit for $4.2 billion

STAT

Becton Dickinson plans to pay $4.2 billion for Edwards Lifesciences’ critical care business, which sells technology that monitors the heart conditions of critically ill patients. Edwards had told investors in December 2023 that it planned to spin off the business in order to focus more sharply on addressing structural defects in the heart. BD, meanwhile, wants to increase its monitoring presence in hospitals.

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Summary care records application to switch off from today

The Pharmacist

The technology that allows pharmacists to view summary care records changes to a new service from today. The Summary Care Record application (SCRa) will be fully switched off and replaced by the National Care Record Service (NCRS), which provides access to more than 63 million records. Users will automatically be redirected to NCRS, according to NHS England.

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Enhance Healthcare Efficiency With Top Payroll & HCM Services

Running a healthcare facility requires precision and care, not just for patients but also for your staff. Our guide, "A Buyer’s Guide to Payroll & HCM Services," helps healthcare providers choose the best provider. Efficient payroll management ensures timely, accurate payments, critical for maintaining staff morale and trust. Compliance support helps navigate complex healthcare regulations and avoid costly fines.

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STAT+: Illumina board agrees to spin off Grail, as divestment plans proceed

STAT

Illumina said Monday afternoon that its board of directors had approved a spin-off of its cancer test subsidiary Grail, signaling that a nearly four-year-long, $8 billion saga will finally draw to a close this month. Shares in the newly independent Grail are expected to be distributed on June 24, Illumina said in a statement. Illumina will retain a 14.5% stake in the company, which will trade under the ticker $GRAL.

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Structure pill leads to competitive weight loss in obesity study

BioPharma Dive

Shares in the company soared by more than 50% as study data showed the pill led to similar levels of weight loss as a rival drug being developed by Eli Lilly.

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STAT wants to know your pick for a great summer read or listen

STAT

S TAT is putting together a list of books and podcasts that deal with health, medicine, and the life sciences that would be great to check out this summer. We invite our readers to fill out the form below, and you may see your pick in our upcoming annual roundup. To get a little inspiration, check out our past lists from 2023 , 2022 , and 2021.

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BIO 2024 - Live Coverage Day 1

pharmaphorum

Join us for live coverage of BIO 2024, featuring Viola Davis and Brooke Baldwin on Day 1. Stay tuned for exclusive updates and highlights from the event.

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Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

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STAT+: Agios drug reduces blood transfusions in patients with beta-thalassemia, study shows

STAT

Agios Pharmaceuticals said Monday that its drug called mitapivat reduced the need for blood transfusions in patients with a severe form of beta-thalassemia, an inherited blood disorder. The results achieved the primary goal of a placebo-controlled Phase 3 clinical trial, and if the drug is eventually cleared by regulators, could accelerate sales. In the study, 30% of participants responded to treatment with mitapivat compared to 12% of participants offered a placebo.

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GSK shares dive on Zantac court case ruling

pharmaphorum

Shares in GSK plummet after Delaware court says litigation claiming Zantac can cause cancer is cleared to go ahead

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STAT+: A short-lived Medicaid freakout sends insurers’ stocks diving

STAT

You’re reading the web version of Health Care Inc., STAT’s weekly newsletter following the flow of money in medicine. Sign up to get it in your inbox every Monday. What’s next for Risant? Kaiser Permanente grabbed everyone’s attention last year when it said it was creating Risant Health, a new and vague entity that acquired Geisinger and had plans to scoop up at least four more health systems that are focused on “value-based care.

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