Mon.May 13, 2024

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CDC launching wastewater dashboard to track bird flu virus spread

STAT

Reluctance among dairy farmers to report H5N1 bird flu outbreaks within their herds or allow testing of their workers has made it difficult to keep up with the virus’s rapid spread , prompting federal public health officials to look to wastewater to help fill in the gaps. On Monday, the Centers for Disease Control and Prevention is expected to unveil a public dashboard tracking influenza A viruses in sewage that the agency has been collecting from 600 wastewater treatment sites around the

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5 trends impacting drug spend in the U.S.

PharmaVoice

Key factors changing how much Americans spend on prescriptions.

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Trending Sources

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Opinion: A dose of reality on adult vaccinations

STAT

The number of children who received their routine vaccinations declined during the pandemic, so public health officials have been focusing on getting kids back up to date. They should also be paying attention to adults as a new, first-of-its-kind report quantifying the economic impact of adult immunizations makes clear. Researchers at the nonprofit Office of Health Economics , based in London, analyzed four adult vaccine programs — for the flu, pneumonia, respiratory syncytial virus (RSV)

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PEM POCUS Series: Soft Tissue Ultrasound

ALiEM - Pharm Pearls

Read this tutorial on the use of point of care ultrasonography (POCUS) for pediatric soft tissue ultrasonography. Then test your skills on the ALiEMU course page to receive your PEM POCUS badge worth 2 hours of ALiEMU course credit. Take the ALiEMU PEM POCUS: Soft Tissue Quiz Case Goals List the indications of performing a pediatric soft tissue point-of-care ultrasound (POCUS).

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Navigating Payroll Compliance: Future-Proofing Payroll in an Evolving Regulatory Landscape

Speaker: Jennifer Hill

Payroll compliance is a cornerstone of business success, yet for small and midsize businesses, it’s becoming increasingly challenging to navigate the ever-evolving landscape of federal, state, and local regulations. Mistakes can lead to costly penalties and operational disruptions, making it essential to adopt advanced solutions that ensure accuracy and efficiency.

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After decades fighting Big Tobacco, Cliff Douglas now leads a foundation funded by his former adversaries

STAT

“Does it trouble you to answer that question?” one of New York’s highest paid attorneys asked Cliff Douglas, then a 36-year-old activist who had found himself at the center of a $10 billion libel lawsuit brought by the cigarette giant Philip Morris. Philip Morris’ lawyer Herbert Wachtell demanded to know: Were cigarette companies intentionally killing people?

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STAT+: FDA is criticized for taking a ‘ministerial’ role in sorting out some pharma patents

STAT

When it comes to a crucial controversy over pharmaceutical patents, the FDA has been MIA. For nearly 20 years, drug companies have asked the Food and Drug Administration for guidance on listing patents for drug-and-device combination products, such as asthma inhalers and auto-injectors for diabetes treatments, in an obscure, but highly important agency registry.

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BREAKING: Government publishes hub and spoke consultation response

The Pharmacist

Hub and spoke dispensing between pharmacies owned by different legal entities will be allowed from 1 January 2025, subject to parliamentary approval, the government has announced. In its consultation response published today, the government proposed introducing two models of hub and spoke dispensing across legal entities. In one model the hub would directly supply the […] The post BREAKING: Government publishes hub and spoke consultation response appeared first on The Pharmacist.

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Opinion: Congress: Close Medicare’s dangerous gaps in coverage for addiction treatment

STAT

While many people immediately picture young adults when thinking about the current addiction and overdose epidemic, this crisis is affecting all generations. In fact, more than 7 million older Americans struggle with substance use disorders. Opioid use disorder, in particular, has skyrocketed among Medicare beneficiaries , with opioid overdose death rates rising higher among people 65 and older than in any other age group.

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Biosimilars are gaining ground. The IRA could push them even further next year.

PharmaVoice

As commercial momentum builds, coverage incentives for the Medicare market are expected to favor biosimilars in 2025.

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From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

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STAT+: Late-stage results set up Cytokinetics heart drug to compete with Bristol

STAT

Late-stage results of Cytokinetics’ drug for a rare heart disease suggest it can compete with a similar treatment sold by Bristol Myers Squibb on efficacy and safety, and can also be dosed more conveniently, potentially making it a more attractive option for doctors if approved. The 24-week Phase 3 trial tested the drug, a daily pill called aficamten, in patients with obstructive hypertrophic cardiomyopathy, or oHCM, a disease in which the heart has more difficulty pumping blood and patie

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Thinking inside the box: How SmartLabs is transforming laboratories for modern science and accelerating innovation

PharmaVoice

SmartLabs offers the first integrated platform combining re-configurable lab infrastructure, operations and scientific expertise.

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STAT+: Can AI build custom ‘n-of-1’ drugs faster? Maybe not yet, new case study suggests

STAT

Two years ago, Yiwei Shi was searching desperately for someone to build a drug for her newborn son, Leo. Leo was born with a very small head, a symptom of many severe diseases. After a seizure at two months, doctors sequenced his genome and found a single misspelling in a gene called TNPO2.  Little was known about the gene, except that it was involved in neurodevelopment.

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Ajax, aiming for a better JAK drug, raises $95M to begin first tests

BioPharma Dive

Goldman Sachs and Eli Lilly are among those backing the startup, which claims its prospect could be more potent than the myelofibrosis therapies that have come to market in recent years.

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Why Every Small Business Needs an HCM Solution: A Comprehensive Guide

Managing HR tasks like payroll, compliance, and employee data can overwhelm small businesses. That’s where a Human Capital Management (HCM) solution comes in. Our eBook, Why Every Small Business Needs an HCM Solution: A Comprehensive Guide , shows how an HCM system automates tedious processes, ensuring your business stays compliant and efficient. You’ll learn how to simplify payroll, eliminate costly errors, and empower your employees with self-service tools.

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STAT+: The stories that shaped our understanding of the health care system

STAT

You’re reading the web version of Health Care Inc., STAT’s weekly newsletter following the flow of money in medicine. Sign up to get it in your inbox every Monday. We did something a little different for this issue: We wanted to share some of the stories that explain the machinations of the U.S. health care system — stories that really influenced how we think about and report on this industry.

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Transforming clinical trials with open-source tech

pharmaphorum

Think open-source is just for software? Think again. Learn how clinical researchers are embracing open data and tools to overhaul the drug development process.

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Genetic variant common among West African descendants contributes to large cardiovascular disease burden

STAT

Among cardiologists, it’s known that transthyretin cardiac amyloidosis, a type of heart disease, is caused by the misfolding of a protein called transthyretin, which builds up in the walls of the heart, causing the muscle to get thicker and stiffer. One reason this can happen is because of a genetic mutation caused by the gene variant V142I, which is commonly found in people of West African descent.

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BBSRC invests £48m in Babraham Institute to advance lifelong health research

Pharma Times

The funding will help to support research across epigenetics, immunology and cell signalling

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Best Practices to Streamline Compensation Management: A Foundation for Growth

Speaker: Joe Sharpe and James Carlson

Payroll optimization can be one of the most time-consuming and complex factors of small business management. Yet, organizations that crack the code on streamlining employee compensation often discover innovative avenues for growth. With the right strategies in place, outsourcing and streamlining payroll processes can result in substantial time and resource savings.

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STAT+: Sandoz disavows U.K. trade group over dispute about promoting a biosimilar for multiple sclerosis

STAT

In an unusual move, Sandoz is no longer cooperating with a U.K. industry trade group following a dispute over allegations that the company inappropriately marketed a biosimilar medicine. At issue was an anonymous complaint filed in May 2023 by a physician who contended that Sandoz unfairly attempted to promote a biosimilar version of Tysabri for treating multiple sclerosis as an affordable option.

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MIT’s new MRI brain light-detecting technique could support brain cell studies

Pharma Times

Bioluminescence used MRI to observe the dilation of luciferase in engineered blood vessels

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STAT+: Pharmalittle: We’re reading about FDA dithering on pharma patents, WHO pandemic talks, and more

STAT

Good morning, everyone, and welcome to another working week. We hope the weekend respite was invigorating and inspiring, because that oh-too predictable routine of online meetings, phone calls, and deadlines has returned. But what can you do? The world, such as it is, continues to spin. So to give it a nudge in a better direction, we are firing up the coffee kettle to brew some cups of stimulation.

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Is digital therapeutics innovation enough for a sustainable future?

pharmaphorum

Digital therapeutics are transforming healthcare, but are they enough for a sustainable future? This post discusses whether innovation in digital therapeutics that empower patients is sufficient for long-term sustainability.

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Enhance Healthcare Efficiency With Top Payroll & HCM Services

Running a healthcare facility requires precision and care, not just for patients but also for your staff. Our guide, "A Buyer’s Guide to Payroll & HCM Services," helps healthcare providers choose the best provider. Efficient payroll management ensures timely, accurate payments, critical for maintaining staff morale and trust. Compliance support helps navigate complex healthcare regulations and avoid costly fines.

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We now know Tome’s gene editing target

STAT

Want to stay on top of the science and politics driving biotech today?  Sign up  to get our biotech newsletter in your inbox. Hello! Today we learn whether AI might help hasten the development of n-of-1 therapies (hint: not yet), explore why the FDA hasn’t offered Orange Book guidance on drug-device combinations, and talk about CRISPR.

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Who delays NICE technology appraisals anyway?

pharmaphorum

NICE technology appraisals for cancer drugs are often delayed - but who's really to blame? This post investigates how the DHSC contributes to hold-ups in access to innovative cancer treatments.

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Melinda French Gates resigns as Gates Foundation co-chair

STAT

Melinda French Gates will step down as co-chair of the  Bill & Melinda Gates Foundation , the nonprofit she and her ex-husband Bill Gates founded and built into one of the world’s largest philanthropic organizations over the past 20 years. “This is not a decision I came to lightly,” French Gates posted on the X platform on Monday.

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MSD has another TIGIT programme setback

pharmaphorum

A phase 3 trial of MSD’s TIGIT antibody has been abandoned after a high rate of discontinuations rendered the study futile

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Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

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Rise of drug-resistant superbugs could make Covid pandemic look ‘minor’, expert warns

The Guardian - Pharmaceutical Industry

Common infections will kill millions if drug resistance through misuse of antibiotics is not curbed, says England’s ex-chief medical officer What is antimicrobial resistance and how big a problem is it? The Covid-19 pandemic will “look minor” compared with what humanity faces from the growing number of superbugs resistant to current drugs, Prof Dame Sally Davies, England’s former chief medical officer, has warned.

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PharmaTimes MSEA and NIEA awards are open for entry

Pharma Times

Both awards are open for entry until 17 May 2024 and the live awards ceremony will take place on 11 July 2024

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When Worlds Collide: The Theory of Real-World Evidence Meets Reality

FDA Law Blog: Biosimilars

By Jeffrey N. Gibbs & Ana Loloei & Véronique Li, Senior Medical Device Regulation Expert — FDA has long touted the use of real-world evidence ( RWE ). Extolling RWE, FDA has said “RWE can be leveraged to bring new products to market, evaluate the safety and effectiveness of existing products for new uses, and assess the continued performance and safety of products once on the market.