Wed.Nov 22, 2023

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Opinion: Physician and Rep. Raul Ruiz: The infectious disease doctor shortage threatens future pandemic preparedness

STAT

In 2009, I was practicing in the emergency department when the H1N1 pandemic emerged. Then, I saw firsthand the vital role infectious disease physicians played in not only facilitating a coordinated public health response, but also helping patients, providers, and the public navigate the uncertainty that comes with confronting a novel virus. While on the frontlines of that pandemic, I depended on our community’s infectious disease specialists as I worked in real-time to provide patients w

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ACMT Toxicology Visual Pearl: Poison Dart Frog

ALiEM - Pharm Pearls

The toxin from the golden poison dart frog most resembles which of the following in its mechanism of action? Botulinum toxin Bufotoxin Grayanotoxin Palytoxin Tetrodotoxin Photo adapted from Wilfried Berns (Wikimedia Commons) Reveal the Answer 3. Grayanotoxin – a sodium channel opener Background The golden poison dart frog ( Phyllobates terribilis ), often considered one of the most poisonous animals on the planet, secretes onto its skin the lipophilic alkaloid batrachotoxin , which irreversibly

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Overdose deaths during pregnancy spiked over the past few years, study says

STAT

Overdose deaths among pregnant or postpartum people skyrocketed between 2018 and 2021, according to new research published Wednesday in JAMA Psychiatry. The study, conducted by the National Institute on Drug Abuse (NIDA) and the National Institutes of Health, compared the incidence of maternal deaths for overdose of commonly misused psychotropic drugs (such as heroin and other opioids, including synthetic ones, or cocaine) among girls and women aged 10 to 44.

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Organon’s chief medical officer wants to change how the world sees women’s health

PharmaVoice

Dr. Juan Camilo Arjona Ferreira joined Organon in September and says the company is “like a lighthouse in women’s health” in its visibility and focus.

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From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

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STAT+: U.S. Anesthesia Partners, Welsh Carson face class action over monopoly allegations

STAT

Union health plans that represent electricians and plumbers in Texas have filed a class-action lawsuit against physician group U.S. Anesthesia Partners and private equity firm Welsh, Carson, Anderson & Stowe. The lawsuit builds on the Federal Trade Commission’s complaint filed in September, which argued USAP and Welsh Carson illegally bought up anesthesia practices across Texas as a way to concentrate market power, gain negotiating leverage over health insurance companies, and raise p

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Flagship-backed microbiome biotech Evelo to shut down

BioPharma Dive

The company said it had not found “a viable alternative” to closing down in the months since it hit a clinical setback and laid off staff.

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More Trending

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Meet the Pharmacist of the Year Award shortlist: Mohammad M Rahman

The Pharmacist

We speak to the Pharmacist/Pharmacy Team of the Year Award shortlist ahead of this year’s General Practice Awards, to be held on 8 December in London. The first entry under the spotlight from this year’s shortlist of six is Mohammad M Rahman, principal pharmacist and head of medicines management at Lewes Primary Care Network and […] The post Meet the Pharmacist of the Year Award shortlist: Mohammad M Rahman appeared first on The Pharmacist.

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What’s behind the urge to scratch that itch? Harvard researchers have a theory

STAT

That itchy feeling isn’t just in your head, in some cases it might actually be all over you. And it may literally get on your nerves. New research published Wednesday in Cell indicates that a common skin bacterium — Staphylococcus aureus — can make you feel itchy by directly acting on nerve cells. Even though itchiness is an everyday sensation, its causes remain mysterious.

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Strides gets USFDA approval for generic Suprep Bowel Prep Kit

Express Pharma

Strides Pharma Science announced that its step‐ down wholly owned subsidiary, Strides Pharma Global Pte., Singapore, has received approval for Sodium Sulphate, Potassium Sulphate and Magnesium Sulphate Oral Solution 17.5g/ 3.13g/ 1.6g per 6 ounces (Product) from the United States Food & Drug Administration (USFDA). The product is bioequivalent and therapeutically equivalent to the Reference Listed Drug (RLD), Suprep Bowel Prep Kit Oral Solution 17.5g/ 3.13g/ 1.6g per 6 ounces of Braintree La

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STAT+: Evelo Biosciences, a microbiome company launched by Flagship, shuts down

STAT

Evelo Biosciences, a startup hoping to use the trillions of microbes in and on the human body to fight disease, is shutting down after running low on cash and seeing multiple drug trial failures. The biotech, which was based in Cambridge, Mass., launched in 2015 and was one of the first companies in the microbiome field, which seeks to treat disease by leveraging bacteria naturally found in and around the body.

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Why Every Small Business Needs an HCM Solution: A Comprehensive Guide

Managing HR tasks like payroll, compliance, and employee data can overwhelm small businesses. That’s where a Human Capital Management (HCM) solution comes in. Our eBook, Why Every Small Business Needs an HCM Solution: A Comprehensive Guide , shows how an HCM system automates tedious processes, ensuring your business stays compliant and efficient. You’ll learn how to simplify payroll, eliminate costly errors, and empower your employees with self-service tools.

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PREDICTOM trial backed by €21m for early Alzheimer’s detection

Pharma Times

The trial will use an AI screening platform to identify those most at risk of dementia - News - PharmaTimes

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Medtronic isn’t afraid of Wegovy’s potential to disrupt

STAT

Want to stay on top of the science and politics driving biotech today?  Sign up  to get our biotech newsletter in your inbox. Hello, everyone. Damian here with an update on biotech’s silly season, a looming showdown in Washington, and the latest twist in the Ozempic panic. This newsletter is taking the next couple days off in the spirit of the holiday, but we’ll be back in your inbox Monday morning.

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Eli Lilly supports Alto Neuroscience in $45m Series C round

Pharmaceutical Technology

The funding will go towards the development of the company's four CNS candidates, with Phase II study data readouts expected by early 2025.

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Opinion: Listen: Living in cancer limbo

STAT

Fifteen years ago, Mara Buchbinder and colleagues came up with the concept of the “patient in waiting.” The concept described a new category of patients created by cutting-edge testing — say, prenatal diagnostics that alerted parents to potential problems, even though they might not appear. The patient in waiting was, quite literally, someone who was waiting to see if they would become ill.

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Best Practices to Streamline Compensation Management: A Foundation for Growth

Speaker: Joe Sharpe and James Carlson

Payroll optimization can be one of the most time-consuming and complex factors of small business management. Yet, organizations that crack the code on streamlining employee compensation often discover innovative avenues for growth. With the right strategies in place, outsourcing and streamlining payroll processes can result in substantial time and resource savings.

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EC approves first-line ovarian cancer treatment

European Pharmaceutical Review

The European Commission (EC) has authorised a Type II variation for the poly (ADP-ribose) polymerase (PARP) inhibitor Rubraca ® (rucaparib). The small molecule treatment is indicated as a first-line maintenance treatment for individuals with advanced ovarian cancer regardless of their BRCA mutation status, who have responded to first-line platinum-based chemotherapy.

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Pharmalittle: European patent agency invalidates a Moderna mRNA patent; pharma ally Eshoo plans to retire

STAT

Good morning! This is Jonathan Wosen, West Coast biotech and life sciences reporter, filling in for Ed Silverman while he’s away from the Pharmalot campus. There won’t be a newsletter this Thursday or Friday because of the Thanksgiving holiday. Speaking of which, if you wake up tomorrow and realize that your turkey hasn’t thawed, never fear, you can safely cook a fully or partially frozen turkey, according to the U.S.

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Thousands of men to participate in UK trial for prostate cancer

Pharma Times

Prostate cancer is responsible for 12,000 deaths every year in the UK - News - PharmaTimes

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Talking techbio with NVIDIA: Accelerated computing, NLP, and GenAI in drug discovery

pharmaphorum

Talking techbio with NVIDIA: Accelerated computing, NLP, and GenAI in drug discovery Mike.

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Enhance Healthcare Efficiency With Top Payroll & HCM Services

Running a healthcare facility requires precision and care, not just for patients but also for your staff. Our guide, "A Buyer’s Guide to Payroll & HCM Services," helps healthcare providers choose the best provider. Efficient payroll management ensures timely, accurate payments, critical for maintaining staff morale and trust. Compliance support helps navigate complex healthcare regulations and avoid costly fines.

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Fully instrumented 3D printed small-scale bioreactor developed

European Pharmaceutical Review

Researchers have reported on the development of a small-scale 3D printed, single-use bioreactor suitable for a broad range of mammalian and microbial cultivation. Overall, the study described in a paper published in Processes , illustrated the possibility of additive manufacturing of radiation-sterilisable, single-use bioreactors. The paper explained that during upstream bioprocess development, small-scale instrumented bioreactors are required to investigate and optimise production processes in

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Lupin launches FDC drug Vilfuro-G for COPD management in India

Express Pharma

Lupin has launched a fixed-dose triple combination drug (FDC) under the brand name Vilfuro-G for management of chronic obstructive pulmonary disease (COPD) in India. The launch follows the approval granted by the Drug Controller General of India for the dry powder inhaler (DPI) product. A company statement informed, “Lupin Vilfuro-G is the only FDC that uniquely combines Vilanterol, Fluticasone Furoate and Glycopyrronium Bromide, for the long-term management and treatment of moderate to severe C

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Signal: Moderna mRNA patent revoked by EPO after Pfizer suit

Pharmaceutical Technology

Pfizer and BioNTech countersued Moderna following an initial August 2022 suit alleging that its patents were overly broad.

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Boris Bachmeier appointed new MD of Romaco Pharmatechnik GmbH

Express Pharma

Boris Bachmeier has just been named by Romaco Holding GmbH as the new Managing Director of the Romaco Pharmatechnik business unit in Karlsruhe (Germany). He will take over from Markus Regner, who has managed the company since 2018 and will be leaving at his own request at the end of November. All blister, heat sealing and rigid tube filling machines traded under the brand names Noack and Siebler are manufactured at the Romaco facility in Karlsruhe. “ I’m delighted to welcome Boris Bachmeier as n

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Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

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Investigating Industry Involvement in Modern Clinical Trials

Pharmaceutical Commerce

Study aims to find ways industry gets involved in the most influential clinical trials, and how transparent these trials are.

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MPs told of ‘huge differences’ pharmacists make in general practice

The Pharmacist

The ‘expertise and safety’ that pharmacists working in general practice can bring to patients has been spotlighted within a parliamentary inquiry. President of the Primary Care Pharmacy Association Dr Graham Stretch was giving evidence to the Health and Social Care Committee’s new inquiry into pharmacy when he highlighted the ‘huge differences’ practice pharmacists have made. […] The post MPs told of ‘huge differences’ pharmacists make in general practice appeared first on The Pharmacist.

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Navigating the shift from low-cost to highest value

Express Pharma

As we wind up another year and mark Express Pharma’s 29th anniversary, let us review the government’s expectations from the life science segment, which are both aspirational and inspirational. At the recent CII 5th Life Sciences Summit 2023, Arunish Chawla, Secretary, Department of Pharmaceuticals (DoP), Ministry of Chemicals & Fertilizers, said, “India has the potential to grow 3-4 times in value by achieving a shift from 10 per cent share of Pharma and MedTech in the manu

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Promising drug targets to be identified by game-changting technology at MIPS Australia

Outsourcing Pharma

An exciting new instrument that will help identify promising drug targets for academia and the pharma industry has been unveiled in Australia by The Monash Institute of Pharmaceutical Sciences (MIPS).

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5 Reasons to Upgrade Your Pharmacy Management Software

Are you still using workarounds to manage your daily operations? To achieve peak performance, it's time to explore other options for specialty and infusion pharmacy software. Streamline pharmacy operations and improve clinical performance with automated processing, real-time data exchange, and electronic decision support. Download this helpful infographic to: Drive efficiency and patient adherence from referral receipt to delivery and ongoing care – all with our Pharmacy Cloud.

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Skin bacteria can save lives

World Pharma News

Infections with antibiotic-resistant bacteria are a growing global problem. Part of the solution may lie in copying the bacteria's own weapons. The research environment in Tromsø has found a new bacteriocin, in a very common skin bacterium. Bacteriocin inhibits the growth of antibiotic-resistant bacteria that are often the cause of disease and can be difficult to treat.

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Genentech and NVIDIA enter generative AI-powered drug discovery deal

Pharmaceutical Technology

Genentech has entered a research partnership with NVIDIA to expedite the discovery and development of new drugs.

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AMR could kill 10 million in 2050, but there’s no profit in stopping it

pharmaphorum

AMR could kill 10 million in 2050, but there’s no profit in stopping it Mike.

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US Senate Committee calls pharma giants for another hearing on drug pricing

Pharmaceutical Technology

A US senate committee scheduled a hearing on prescription drug pricing with major pharmaceutical companies.

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Blow to Moderna as EU nixes mRNA vaccine patent

pharmaphorum

Blow to Moderna as EU nixes mRNA vaccine patent Phil.

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