Wed.Nov 29, 2023

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STAT+: UnitedHealth Group now employs or is affiliated with 10% of all physicians in the U.S.

STAT

UnitedHealth Group has about 90,000 employed or affiliated doctors, approximately 10% of all physicians in the U.S. The number — disclosed Wednesday at the company’s investor day by Amar Desai, the CEO of UnitedHealth’s Optum Health division — means the company acquired or hired 20,000 doctors in the past year alone. The rapid growth of UnitedHealth’s physician base underscores how the company, which already is the country’s largest private health insure

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ACMT Toxicology Visual Pearl: Needle to Necrosis

ALiEM - Pharm Pearls

Which of the following agents, when injected along with heroin, is associated with the skin changes pictured? Cocaine Fentanyl Methamphetamine Xylazine Photo by Dr. Matthew Salzman Reveal the Answer 4. Xylazine Background Xylazine is a synthetic substance approved by the U.S. Food and Drug Administration for veterinary use, specifically for its muscle relaxant, sedative, and analgesic effects [1].

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STAT+: Colon cancer prevention paradox: Higher-risk patients pay more for colonoscopy

STAT

Ashley Conway-Anderson was prepared for a lot of things when it came to her first colonoscopy. She sought out tips to make the daylong prep more bearable. She braced herself mentally for what the doctors would find; her mother, after all, was just a couple years out of recovery from colorectal cancer. When she awoke from the procedure, she said, things seemed relatively fine.

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Pharma benefited from basing business overseas. An international tax effort could spur a rethink.

PharmaVoice

U.S. tax law changes six years ago slashed large pharma companies' rates and saved them billions. Now, a push for an international floor could disrupt their R&D accounting.

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From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

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With latest tranche, U.K. Biobank has genome sequences from 500,000 people available for research

STAT

LONDON — Data from half a million people’s whole genome sequences are now available to researchers worldwide, as the U.K. Biobank on Thursday debuted the latest addition to what it aims to be the world’s most comprehensive health data resource. The Biobank has been building its collection over 20 years, with 500,000 volunteers recruited to provide survey responses about their health, medical records, tests of molecular markers, and imaging scans.

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Octave Bioscience is navigating the Parkinson’s labyrinth with Michael J. Fox’s help

PharmaVoice

A grant from the notorious Parkinson’s foundation has sped up Octave’s timeline to further advance biomarker development in the field.

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FDA names chief scientist Bumpus as Woodcock’s successor

BioPharma Dive

Bumpus, a former Johns Hopkins professor, named “creating a new model” for the FDA’s Office of Regulatory Affairs as one of her priorities when she steps into the role.

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STAT+: Cigna, Humana in talks to merge into health insurance giant, per report

STAT

Cigna and Humana are in discussions to merge, a potential move that would create a health insurance and prescription drug benefits titan with approximately $300 billion of annual revenue. A proposed transaction would almost certainly prompt a close review from antitrust enforcers at the Department of Justice and the Federal Trade Commission. A merged Cigna-Humana would further consolidate the market for pharmacy benefit managers.

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Milner Therapeutics to establish new genomics laboratory for drug discovery

Pharma Times

The new state-of-the-art facility is set to be operational in early 2024 - News - PharmaTimes

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STAT+: FDA chief scientist to replace Woodcock

STAT

WASHINGTON — The Food and Drug Administration’s chief scientist will replace retiring Janet Woodcock as principal deputy commissioner of the agency next year, the FDA commissioner announced Wednesday. Namandjé N. Bumpus was named chief scientist in June of last year. The chief scientist works closely with the FDA’s product centers, and Bumpus played a big role in the expansion of the agency’s regulation of cosmetics.

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Why Every Small Business Needs an HCM Solution: A Comprehensive Guide

Managing HR tasks like payroll, compliance, and employee data can overwhelm small businesses. That’s where a Human Capital Management (HCM) solution comes in. Our eBook, Why Every Small Business Needs an HCM Solution: A Comprehensive Guide , shows how an HCM system automates tedious processes, ensuring your business stays compliant and efficient. You’ll learn how to simplify payroll, eliminate costly errors, and empower your employees with self-service tools.

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Ferring reveals long-term data for cancer gene therapy

European Pharmaceutical Review

Following the US Food and Drug Administration (FDA)’s approval of Ferring Pharmaceuticals’ gene therapy Adstiladrin ® (nadofaragene firadenovec-vncg) in December 2022, new long-term follow up data has been revealed. Adstiladrin is the first FDA-approved intravesical gene therapy to be authorised for adults with high-risk Bacillus Calmette-Guérin (BCG)-unresponsive non-muscle invasive bladder cancer (NMIBC) with carcinoma in situ (CIS) with or without papillary tumours.

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STAT+: Blood cancers may arise from CAR-T cells, but experts think only in very rare cases

STAT

The announcement on Tuesday that the Food and Drug Administration was investigating whether CAR-T immunotherapy had itself caused blood cancers initially appeared to be a significant blow to one of the brightest spots in cancer care. But experts quickly cautioned that risk of this complication is probably minuscule compared to the known risk of secondary cancers from other cancer therapies like chemotherapy and radiation.

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FDA Investigating Risk of Secondary Cancers in Patients Administered CAR T-Cell Therapy

PharmExec

The FDA will investigate all currently approved CAR T-cell treatments, as well as BCMA-directed and CD19-directed genetically modified autologous CAR T-cell therapies, for the risk of secondary T-cell malignancies.

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Opinion: Listen: What we take for granted after 30 years of Prozac

STAT

When Prozac first entered the psychiatry scene in in the late ’80s, the profession was still Freud’s territory. Many considered taking medication to treat depression a failure. But that was all about to change, as early stewards like psychiatrist Peter Kramer refused to shy away from the new drug’s potential. These days, he says that people take for granted all of the progress that’s been made with antidepressant treatment in the past three decades.

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Best Practices to Streamline Compensation Management: A Foundation for Growth

Speaker: Joe Sharpe and James Carlson

Payroll optimization can be one of the most time-consuming and complex factors of small business management. Yet, organizations that crack the code on streamlining employee compensation often discover innovative avenues for growth. With the right strategies in place, outsourcing and streamlining payroll processes can result in substantial time and resource savings.

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16th CPHI & PMEC India 2023 redefines pharma landscape

Express Pharma

South Asia’s largest Trade Fair for pharma brought together over 50,000 visitors from across the globe, more than 1,500 exhibitors showcasing 10,000+ products and representation from over 80 countries Initiating a groundbreaking expedition to reshape the landscape of pharma manufacturing, CPHI & PMEC India 2023 commenced yesterday at the India Expo Centre in Greater Noida, Delhi-NCR.

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STAT+: Saudi VC loops Novo Nordisk, other biotech VCs into new longevity incubator

STAT

The Hevolution Foundation, a Saudi investment firm focused on aging science, said Wednesday that it is launching an incubator that will bring together experts from the scientific community, pharma, and multiple biotech VCs. The incubator, called the Breakthrough Innovation Alliance, will give up to $1 million apiece to 10 different research initiatives over the next three years, allowing scientists and entrepreneurs to run preclinical research to determine whether the ideas hold any promise.

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Pharma unite to secure renewable energy in key manufacturing markets

European Pharmaceutical Review

For the first time, companies across the global healthcare sector, including AstraZeneca , GSK, Novo Nordisk and Roche, have united to discuss with energy providers in China and India, about scaling renewable power across their supply chains. This step is important as these countries are key markets for pharmaceuticals manufacturing. Based on data on sales/value-based shares from various companies for APIs and Chemicals, India and China are estimated to account for up to half of materials for me

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U.S. life expectancy rose in 2022, but it remains below its pre-pandemic level

STAT

NEW YORK — U.S. life expectancy rose last year — by more than a year — but still isn’t close to what it was before the Covid-19 pandemic. The 2022 rise was mainly due to the waning pandemic, Centers for Disease Control and Prevention researchers  said Wednesday. But even with the large increase, U.S. life expectancy is only back to 77 years, 6 months — about what it was two decades ago.

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Enhance Healthcare Efficiency With Top Payroll & HCM Services

Running a healthcare facility requires precision and care, not just for patients but also for your staff. Our guide, "A Buyer’s Guide to Payroll & HCM Services," helps healthcare providers choose the best provider. Efficient payroll management ensures timely, accurate payments, critical for maintaining staff morale and trust. Compliance support helps navigate complex healthcare regulations and avoid costly fines.

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BioMarin secures hemophilia gene therapy coverage in Germany

BioPharma Dive

Drawn-out negotiations led to a lower price than initially expected, but analysts called the agreement a step forward for the biotech company.

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Flagship Pioneering crosses the pond, opens a European front

STAT

Want to stay on top of the science and politics driving biotech today?  Sign up  to get our biotech newsletter in your inbox. Good morning, everyone. Damian here with the latest twist for a futuristic cancer therapy, big money for longevity research, and a dispatch from London.

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CSL, Arcturus get first approval for self-assembling RNA jab

pharmaphorum

Japan’s medicines regulator has approved the first vaccine based on self-assembling RNA, a spin on the mRNA technology used in current shots, which is designed to deliver greater efficacy with a lower dose.

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10th edition of India Pharma Awards at CPHI celebrates a decade of excellence and innovation in pharma industry

Express Pharma

The selection process was guided by EY and evaluated by a distinguished jury, including a Preliminary Online Jury meet and finalist presentations The India Pharma Week 2023, started from 28 th November till 30 th November on the sidelines of the CPHI show. Day one marked the 10 th annual India Pharma Awards, hosted by Informa Markets, and CEO roundtable discussion.

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Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

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Gilead to lay off staff at cell therapy unit Kite

BioPharma Dive

The cuts will impact 7% of the cancer drug division’s employees, although about 90 new roles will be created around “areas of growth.

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GP surveillance to increase after human swine flu case

The Pharmacist

A new strain of swine flu has been detected in humans for the first time in the UK, picked up via routine testing by the patient’s GP. The UK Health Security Agency (UKHSA) will now ‘increase surveillance’ at GP surgeries in this area. There have been 50 human cases of the influenza A(H1N2)v strain globally […] The post GP surveillance to increase after human swine flu case appeared first on The Pharmacist.

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Japan grants approval for CSL and Arcturus’ Covid-19 vaccine 

Pharmaceutical Technology

Japan’s MHLW has approved CSL and Arcturus Therapeutics’ self-amplifying mRNA (sa-mRNA) Covid-19 vaccine, ARCT-154.

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Learning Clinical Microbiology Using Podcasting: The Let’s Talk Micro Podcast

ID Stewardship

In this article the host of the Let’s Talk Micro Podcast (Luis Plaza Rios) is interviewed about his experience and learning clinical microbiology using podcasting via the Let’s Talk Micro podcast. Interviewee: Luis Plaza Interviewer: Timothy P. Gauthier, Pharm.D., BCPS, BCIDP Article Posted 1 December 2023 Podcasting has emerged as an incredible way to reach a global audience and discuss scientific information.

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5 Reasons to Upgrade Your Pharmacy Management Software

Are you still using workarounds to manage your daily operations? To achieve peak performance, it's time to explore other options for specialty and infusion pharmacy software. Streamline pharmacy operations and improve clinical performance with automated processing, real-time data exchange, and electronic decision support. Download this helpful infographic to: Drive efficiency and patient adherence from referral receipt to delivery and ongoing care – all with our Pharmacy Cloud.

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FDA kicks off review of Karuna’s schizophrenia drug KarXT

pharmaphorum

Karuna Therapeutics said this morning that the FDA has formally started its review of KarXT, aiming to become the first drug to reach the market for schizophrenia with a new mechanism of action in decades.

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'High Severity' Flu Season Among Children Spotlights Importance of Vaccination

PharmExec

The CDC’s Morbidity and Mortality Weekly Report show pediatric influenza hospitalization rates returned to levels that preceded the COVID-19 pandemic.

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AbbVie cues up filing for c-Met ADC in lung cancer

pharmaphorum

AbbVie is preparing to file for accelerated approval of telisotuzumab vedotin (Teliso-V) as a treatment for some patients with lung cancer after the drug hit the mark in a pivotal phase 2 trial.

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VPAS is dead, long live VPAG—could the UK’s new clawback revision save the day?    

Pharmaceutical Technology

After months of negotiations, the UK's DHSC and the Association of the British Pharmaceutical Industry emerged with a plan on to replace VPAS.

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GP and pharmacy bus project steers Newcastle health drive

The Pharmacist

A partnership between Newcastle GP Services and Newcastle University’s School of Pharmacy has seen the launch of a community health bus, providing the city’s residents with a range of healthcare services. The purpose-built bus will be visiting a variety of locations in the city, staffed by registered nurses, Newcastle pharmacy students and Northumbria University nursing […] The post GP and pharmacy bus project steers Newcastle health drive appeared first on The Pharmacist.

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