Thu.May 02, 2024

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Scientists spot an orangutan using a plant to treat his own wound in the wild

STAT

When male Sumatran orangutans let out a long call, they’re usually trying to grab female attention. But the sounds — a booming blend of roars and grunts — can end up attracting unwanted attention from other males, too. Things can get tense. Which is likely how Rakus, an adult male orangutan frequently seen in Gunung Leuser National Park in South Aceh, Indonesia, acquired a face wound in June 2022.

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$4M+ gene therapies? How payers can adapt to a new reality of pricey ‘cures’

PharmaVoice

Pricey gene therapies promise great benefit to patients but pose a threat to the payer landscape — ICER and a Tufts think tank are offering potential solutions.

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Trending Sources

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Tracking bird flu virus changes in cows is stymied by missing data, scientists say

STAT

Another upload of genetic sequence data from the H5N1 bird flu outbreak in dairy cattle has exacerbated the scientific community’s frustration with the U.S. Department of Agriculture after the agency again failed to include basic information needed to track how the virus is changing as it spreads. Like a large tranche of sequences that the USDA uploaded to a public database on April 21, this week’s data dump did not include information about where and when the sequenced samples wer

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Nova’s Xromi approved in UK and EU for vaso-occlusive complications of SCD

Pharma Times

The inherited disorder is caused by genetic mutations that affects haemoglobin production

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Navigating Payroll Compliance: Future-Proofing Payroll in an Evolving Regulatory Landscape

Speaker: Jennifer Hill

Payroll compliance is a cornerstone of business success, yet for small and midsize businesses, it’s becoming increasingly challenging to navigate the ever-evolving landscape of federal, state, and local regulations. Mistakes can lead to costly penalties and operational disruptions, making it essential to adopt advanced solutions that ensure accuracy and efficiency.

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Bird flu virus circulated in cows for four months before outbreak confirmed by USDA, analysis shows

STAT

As agricultural authorities and epidemiologists try to get their arms around the scope of the latest confounding chapter in the decades-long story of the H5N1 avian influenza virus — its j ump into U.S. herds of dairy cattle — they’re turning to the genetic breadcrumbs the virus leaves behind in the animals’ nose, lungs, and, primarily, milk.

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STAT+: Biological clocks could be the key to longer, healthier lives. But scientists don’t yet agree on what ‘aging’ is

STAT

It’s no secret that a lucky few seem to glide into old age, the years settling gracefully on their bodies, while others appear to have been dragged through time tied to a metaphorical garbage truck. Biologists have been developing numerous ways to measure the rate an individual ages — often called an accelerated or decelerated “biological age” — and trying to translate it into a heightened or reduced risk of the morbidity and mortality that comes with aging.

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New patient card to be introduced for finasteride

The Pharmacist

A patient alert card warning of potential psychiatric and sexual side effects of finasteride will be introduced into packs the medicine this year, following a review into the drug’s safety. Finasteride is used by men as a 1mg dose under the brand name Propecia to treat hair loss, and as a 5mg dose under the […] The post New patient card to be introduced for finasteride appeared first on The Pharmacist.

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STAT+: Amgen goes all in on injectable obesity drug as it scraps early-stage pill

STAT

Amgen said Thursday that it will no longer develop an early-stage obesity pill, and will instead focus on a more advanced injectable candidate that’s seen as a potential competitor to Novo Nordisk’s Wegovy and Eli Lilly’s Zepbound. The injectable drug, called MariTide, is in a Phase 2 trial for obesity, and Chief Executive Bob Bradway said on an earnings call that “we are very encouraged with the results” from an interim analysis of that trial.

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The top pharmaceutical companies by R&D expenditure

Pharmaceutical Technology

From Merck & Co to Sanofi, Pharmaceutical Technology lists the leading pharmaceutical companies spending the most on R&D in 2023.

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From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

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Opinion: Why isn’t there agreement on when women need to start getting mammograms?

STAT

If, after reading the latest recommendation on breast cancer screening by the United States Preventive Services Task Force (USPSTF), you feel like your head is spinning, that’s understandable. The task force’s newest advice , which gives a “B” grade in favor of routine mammograms for women in their 40s, reverses its 2016 statement saying the test should be optional for such women.

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Pace, acceleration, and precision are the name of the game

pharmaphorum

Security and privacy within biotech are critical points of consideration and discussion as the industry continues to innovate at speed, and it is such aspects that are central to today’s podcast with Zach Powers, chief information security officer at Benchling, the R&D cloud platform for the biotech industry.

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Opinion: The U.S. needs a reliable supply of baby formula. A new bill in Congress can help

STAT

Families in America should never have to scrounge for baby formula. The United States needs a diverse and resilient supply of infant formula. Boosting the ability of smaller companies to compete in this market against the three large formula makers — Abbott, Mead Johnson, and Nestlé Gerber — could help make shortages a thing of the past.

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Long-acting antibody demonstrates promising efficacy in infant RSV

European Pharmaceutical Review

Interim results of an ongoing study published in The Lancet have reported that Beyfortus (nirsevimab) reduced respiratory syncytial virus (RSV) hospitalisations by 82 percent in infants under six months, compared to infants who received no RSV intervention. Sanofi noted that as a long-acting antibody, Beyfortus has been shown to provide rapid protection, helping to prevent lower respiratory tract disease caused by RSV without the immune system needing activation.

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Why Every Small Business Needs an HCM Solution: A Comprehensive Guide

Managing HR tasks like payroll, compliance, and employee data can overwhelm small businesses. That’s where a Human Capital Management (HCM) solution comes in. Our eBook, Why Every Small Business Needs an HCM Solution: A Comprehensive Guide , shows how an HCM system automates tedious processes, ensuring your business stays compliant and efficient. You’ll learn how to simplify payroll, eliminate costly errors, and empower your employees with self-service tools.

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STAT+: Novartis extends radiopharma plans with $1 billion acquisition

STAT

Novartis already produces the leading drug in the radiopharmaceutical field. Now, it is devoting even more attention to these cancer treatments with a new acquisition.  Novartis is paying $1 billion upfront and up to an additional $750 million if certain milestones are met to acquire startup Mariana Oncology, the latter company announced Thursday.

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Reunion raises over $100M to build a better psychedelic drug

BioPharma Dive

The funding will help Reunion pay for a mid-stage study testing its most advanced medicine — essentially a synthetic version of the hallucinogenic psilocin — in women with postpartum depression.

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STAT+: Gilead gets a boost from California court in a case over slow-walking an HIV drug

STAT

In a boost for Gilead Sciences, the California Supreme Court agreed to review a contentious legal theory that thousands of HIV patients have used in a closely watched case to argue drugmakers can be held negligent for failing to develop a medicine. Earlier this year, a state appeals court ruled the company could be held liable for halting further development of an HIV medicine that was safer than an HIV drug it was already selling.

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Delphia starts up with $67M to make a new type of cancer drug

BioPharma Dive

Delphia is developing medicines designed to overstress certain cellular pathways to the point tumor cells die, an approach the biotech calls “activation lethality.

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Best Practices to Streamline Compensation Management: A Foundation for Growth

Speaker: Joe Sharpe and James Carlson

Payroll optimization can be one of the most time-consuming and complex factors of small business management. Yet, organizations that crack the code on streamlining employee compensation often discover innovative avenues for growth. With the right strategies in place, outsourcing and streamlining payroll processes can result in substantial time and resource savings.

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STAT+: Transcarent, Glen Tullman’s health tech unicorn, raises $126 million

STAT

Transcarent, the fast-moving company helmed by health tech investor and former Livongo CEO Glen Tullman, today announced $126 million in Series D funding valuing the company at $2.2 billion. The investment round was led by venture capital giant General Catalyst and 7wireVentures, where Tullman is a managing partner. Transcarent will use the funding to support development of artificial intelligence capabilities across the enterprise, growing its business, and pursuing acquisitions, Tullman told S

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Mobile app guides patients through surgical recovery

pharmaphorum

Hospital staff in the UK have developed and piloted an app that can help patients monitor their progress to recovery after surgeries.

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STAT+: Novo Nordisk defends Ozempic’s price in face of Senate scrutiny

STAT

Novo Nordisk defended the prices of its blockbuster diabetes and obesity drugs Ozempic and Wegovy amid a Senate probe into what the company charges. Speaking on an earnings call Thursday, CEO Lars Fruergaard Jørgensen said the company launched the treatments at similar prices to earlier generations in the drug class, despite their having greater efficacy, making them “an attractive value proposition.

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RNA glioblastoma vaccine shows promise in first human trial

pharmaphorum

A personalised vaccine for the aggressive brain cancer glioblastoma developed has shown encouraging signs of efficacy in its first human trial.

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Enhance Healthcare Efficiency With Top Payroll & HCM Services

Running a healthcare facility requires precision and care, not just for patients but also for your staff. Our guide, "A Buyer’s Guide to Payroll & HCM Services," helps healthcare providers choose the best provider. Efficient payroll management ensures timely, accurate payments, critical for maintaining staff morale and trust. Compliance support helps navigate complex healthcare regulations and avoid costly fines.

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STAT+: BridgeBio spins out oncology company as it focuses on heart drug

STAT

BridgeBio Pharma is spinning out its oncology subsidiary into a fully independent company, as it concentrates its resources on an anticipated launch of its pivotal heart drug. The subsidiary, a company called TheRAS that is developing treatments for cancers with mutations in the KRAS gene, will become BridgeBio Oncology Therapeutics. The spinout is backed by $200 million in private financing led by Cormorant Asset Management and Omega Funds, with participation from other firms including Deerfiel

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MHRA publishes strategy on AI regulation

European Pharmaceutical Review

The Medicines and Healthcare products Regulatory Agency (MHRA) has published a policy paper on its strategic approach to artificial intelligence (AI). It summarises the MHRA’s view on the UK government’s white paper on AI regulation published in 2023. Following publication of this white paper, the government requested that the MHRA outline the steps the agency is working on in relation to its expectations.

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STAT+: Lawmakers unlikely to permanently extend telehealth flexibilities this year

STAT

WASHINGTON — Members of Congress appear poised to advance another short-term extension of pandemic-era telehealth flexibilities instead of permanently addressing the issue, seven sources familiar with the talks said. During the Covid-19 pandemic, lawmakers allowed Medicare patients to access telehealth services in more places and for a greater variety of providers than before, but some of those flexibilities are set to expire at the end of the year.

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Unravelling the impact of ICH E6(R3) on Good Clinical Practice

pharmaphorum

The updated ICH E6(R3) Good Clinical Practice guidelines are here - discover what's changed and how clinical trials will need to adapt. This in-depth post unravels the key impacts of E6(R3).

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Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

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STAT+: Novartis’ $3 billion MorphoSys boondoggle

STAT

This is the online edition of Adam’s Biotech Scorecard, a new subscriber-only newsletter. STAT+ subscribers can sign up  here  to get it delivered every Thursday to their inbox. Boston-area beaches are closed to dogs starting May 1, so Bo got one last chance this past weekend to dig and play in the sand. Pssst: You can sneak your dog to Wingaersheek Beach on summer nights, after the parking monitors leave at 5 p.m.

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Educating on the rewards of a career in life sciences

pharmaphorum

Pursue your passion for science with a rewarding career in life sciences. Learn how a job in biology, biotech, or health sciences offers intellectual stimulation and the chance to improve lives.

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The biotech news you need to read this morning

STAT

Want to stay on top of the science and politics driving biotech today?  Sign up  to get our biotech newsletter in your inbox. Good morning, we’re nearing the end of my second week writing this newsletter. I want to know what you think! Share your feedback in  this survey  if you haven’t already.