Fri.Oct 25, 2024

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STAT+: For the behemoth UnitedHealth, a new threat to Medicare profits

STAT

For the nation’s largest health insurer, the evidence of abuse was stunning and unmistakable: UnitedHealth Group reaped billions from the federal Medicare program by diagnosing patients with serious chronic illnesses, and then delivering no follow-up care. The findings in the federal report reveal that UnitedHealth repeatedly sent clinicians into patients’ homes and pored over their medical charts to add diagnoses for illnesses such as vascular disease, heart failure, and diabetes.

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SAEM Clinical Images Series: When Needles Go Beyond Sewing and Acupuncture

ALiEM - Pharm Pearls

A 64-year-old male with a history of bipolar 1 disorder, PTSD, anxiety, depression, obsessive-compulsive disorder, GERD, and HTN presented to the ED with the chief complaint of foreign body and self-injury. He reported years of sticking sewing needles into his right arm, most recently yesterday. He explained that inserting needles makes him feel better with mild associated pain.

Vaccines 177
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In the era of GLP-1 drugs, demand for bariatric surgery plunges

STAT

For people with obesity, surgeries that shrink, reshape, or otherwise alter the anatomy of the stomach have long reigned supreme as the surest way to weight loss. But in the last few years, with the approval of GLP-1 drugs like Wegovy and Zepbound , more and more people are opting for obesity medicines over gold-standard surgical treatments.  “On a population level, among a subset of commercially insured individuals, that is the tradeoff that is happening” said Thomas Tsai, th

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GSK plans $800m US manufacturing investment

pharmaphorum

GSK has made another investment in its manufacturing network, setting aside $800 million to build two plants at its Marietta site in the US.The programme represents the largest capital spend by the UK drugmaker on production capacity to date and will double the size and capacity of GSK's existing medicines and vaccines facility in Marietta, Pennsylvania, creating around 200 new jobs.

Vaccines 101
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From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

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STAT+: Eli Lilly weight loss drug shortage underscores deeper issues with FDA oversight

STAT

A turbulent series of events surrounding the supply of Eli Lilly’s blockbuster weight loss treatment has raised concerns around how the Food and Drug Administration maintains its list of drug shortages and which sources it relies on, an issue that affects a growing number of Americans. Earlier this month, the FDA declared an end to the shortage of Lilly’s tirzepatide, sold as Mounjaro for diabetes and Zepbound for obesity, after almost two years.

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Dr Reddy’s Laboratories among top 15 biotech and pharma employers in Science Magazine Survey

Express Pharma

Dr Reddy’s Laboratories has been recognised among the top employers in the global biotech and pharma sectors, according to the 2024 Top Biotech and Pharma Employers Survey by Science magazine. This marks the third consecutive year that Dr Reddy’s has secured a place in the survey’s top rankings. Dr Reddy’s first entered the list in 2022, ranked 18th.

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J&J’s comeback kid Spravato heads for blockbuster status

PharmaVoice

After a slow start, the novel esketamine nasal spray for depression is now J&J’s fastest-growing medication.

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Being a patient can be a full-time job. This ICU nurse wants to make it easier

STAT

Michael Anne Kyle had just begun her Ph.D. in health policy and management at Harvard Business School when her friends started complaining about the health care system. Many of them were having children for the first time, and they’d never been to the doctor so much in their lives. They’d text Kyle, who is also an ICU nurse, with gripes.

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Intellia trumpets CRISPR drug data, but shares fall

pharmaphorum

Intellia reports a big reduction in hereditary angioedema attacks in patients treated with its one-shot CRISPR drug, but its share fall sharply

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STAT+: Eli Lilly weight loss drug shortage underscores deeper issues with FDA oversight

STAT

A turbulent series of events surrounding the supply of Eli Lilly’s blockbuster weight loss treatment has raised concerns around how the Food and Drug Administration maintains its list of drug shortages and which sources it relies on, an issue that affects a growing number of Americans. Earlier this month, the FDA declared an end to the shortage of Lilly’s tirzepatide, sold as Mounjaro for diabetes and Zepbound for obesity, after almost two years.

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Why Every Small Business Needs an HCM Solution: A Comprehensive Guide

Managing HR tasks like payroll, compliance, and employee data can overwhelm small businesses. That’s where a Human Capital Management (HCM) solution comes in. Our eBook, Why Every Small Business Needs an HCM Solution: A Comprehensive Guide , shows how an HCM system automates tedious processes, ensuring your business stays compliant and efficient. You’ll learn how to simplify payroll, eliminate costly errors, and empower your employees with self-service tools.

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Pharmacy minister gets flu jab at Bristol independent

The Pharmacist

Pharmacy minister and Labour MP for Aberafan Maesteg Stephen Kinnock received his annual winter flu vaccination on a visit to Bedminster Pharmacy in Bristol yesterday (24 October). He said he was 'delighted' to visit the pharmacy 'and see first-hand the fantastic work they do'. And he said he had 'heard about the challenges that pharmacies […] The post Pharmacy minister gets flu jab at Bristol independent appeared first on The Pharmacist.

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Opinion: Louisiana’s creative new ways to fight maternal mortality

STAT

You don’t have to be a public health professional to know that the U.S. has the  highest maternal mortality  rate of any high-income country. It’s chilling, sobering, and unacceptable. The situation is particularly dire for Black women, who are  four times more  likely to die than white women. Conditions are worse in Southern states.

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Single-use vapes to be banned from next summer

The Pharmacist

Single-use disposable vapes will be banned in England and Wales from summer next year, the government has confirmed. New legislation to prohibit the sales of single-use vapes will come into force on 1 June 2025, ministers said. Subject to parliamentary approval, businesses will have until then to sell any remaining stock and prepare for the […] The post Single-use vapes to be banned from next summer appeared first on The Pharmacist.

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Morning Rounds: Newborn screenings, radiation-proof tardigrades

STAT

Get your daily dose of health and medicine every weekday with STAT’s free newsletter Morning Rounds.  Sign up here. Fun fact: My Ph.D. dissertation was about destroying toxic “forever chemicals,” aka PFAS. This mostly means I am cursed with knowing too much about where these chemicals are used.

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Best Practices to Streamline Compensation Management: A Foundation for Growth

Speaker: Joe Sharpe and James Carlson

Payroll optimization can be one of the most time-consuming and complex factors of small business management. Yet, organizations that crack the code on streamlining employee compensation often discover innovative avenues for growth. With the right strategies in place, outsourcing and streamlining payroll processes can result in substantial time and resource savings.

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Trial highlights potential next-gen biologic for lung cancer

European Pharmaceutical Review

New clinical data has shown a potential best-in-class next-generation antibody-drug conjugate (ADC) can offer promising response rates in extensive-stage small cell lung cancer. The biologic ZL-1310 is being investigated in an ongoing Phase Ia/Ib study in these patients who have had at least one platinum-based chemotherapy regimen. Overall response rate was 74 percent in individuals with at least one post-treatment evaluation.

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STAT+: Pharmalittle: We’re reading about FDA oversight of shortages, AstraZeneca threats, and more

STAT

And so, another working week will soon draw to a close. Not a moment too soon, yes? This is, you may recall, our treasured signal to daydream about weekend plans. Our agenda is, so far, rather modest. We plan to manicure the Pharmalot grounds, promenade with the official mascots, and sample some natural wonders. We also hope to hold another listening party, where the rotation will likely include this , this , this , this , and this.

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Pharma companies must adapt to keep pace with AI developments, say experts

Pharmaceutical Technology

At the Outsourcing in Clinical Trials Conference, key opinion leaders shared predictions for workflow changes due to AI.

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STAT+: Up and down the ladder: The latest comings and goings

STAT

Hired someone new and exciting? Promoted a rising star? Finally solved that hard-to-fill spot? Share the news with us, and we’ll share it with others.  That’s right. Send us your changes, and we’ll find a home for them. Don’t be shy. Everyone wants to know who is coming and going. And here is our regular feature in which we highlight a different person each week.

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Enhance Healthcare Efficiency With Top Payroll & HCM Services

Running a healthcare facility requires precision and care, not just for patients but also for your staff. Our guide, "A Buyer’s Guide to Payroll & HCM Services," helps healthcare providers choose the best provider. Efficient payroll management ensures timely, accurate payments, critical for maintaining staff morale and trust. Compliance support helps navigate complex healthcare regulations and avoid costly fines.

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MSD buys Modifi for $1.3bn to boost oncology pipeline

pharmaphorum

MSD buys Modifi Bio in a $1.3bn deal, getting rights to a new class of drugs for difficult-to-treat cancers, including glioblastoma.

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Bayer and Dewpoint Therapeutics sign licensing agreement for heart disease program

World Pharma News

Bayer has entered into an exclusive licensing agreement with Dewpoint Therapeutics, Inc. for a heart disease program to treat dilated cardiomyopathy (DCM) patients, who are characterized through carrying specific mutations. This is the first option exercise under the research collaboration between Bayer and Dewpoint Therapeutics, Inc., which began in November 2019.

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Tech & Trials: Can AI save us from drowning in data?

pharmaphorum

Explore the potential of AI in navigating the vast amounts of data in clinical trials. Discover how this technology is revolutionising the healthcare industry, in a new Tech & Trials column.

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Top 20 employers in global biotech and pharma sectors revealed

Express Pharma

The 2024 Top Biotech and Pharma Employers Survey conducted by Science magazine has revealed the top 20 employers in the global biotech and pharmaceutical sectors. The survey gathered insights from employees working in biotechnology, biopharmaceutical, pharmaceutical, and related industries, highlighting the companies that stand out as preferred workplaces.

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Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

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GSK pumps up to $800m for US manufacturing site upgrade

Pharmaceutical Technology

A new vaccines drug substance facility and R&D pilot plant, completed by the end of 2028, will create over 200 new jobs.

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Pharmacies ‘losing out’ while government unsure how many dispense at a loss

The Pharmacist

The government does not hold information on how many and what proportion of community pharmacies have dispensed medications at a loss, the minister of state for care has said. But the National Pharmacy Association (NPA) has estimated this number at 85% of its independent contractor members and warned that 'frequently, pharmacies find themselves losing out'. […] The post Pharmacies ‘losing out’ while government unsure how many dispense at a loss appeared first on The Pharmacist.

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NICE backs two AIs for remote heart failure monitoring

pharmaphorum

NICE backs two AI algorithms from Boston Scientific and Medtronic for monitoring heart failure patients, but turns down others from Biotronik and Abbott.

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MHRA urges pharmacists to be alert to signs of GLP-1 RA ‘misuse’

The Pharmacist

The medicines regulator has urged pharmacists to be alert to signs of ‘misuse’ of GLP-1 receptor agonists for weight loss, such as semaglutide. Healthcare professionals should also ensure patients are aware of the side-effects of the diabetes and weight loss injections and report any adverse reactions through the Yellow Card reporting scheme, the Medicines and Healthcare […] The post MHRA urges pharmacists to be alert to signs of GLP-1 RA ‘misuse’ appeared first on The Pharmacist.

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5 Reasons to Upgrade Your Pharmacy Management Software

Are you still using workarounds to manage your daily operations? To achieve peak performance, it's time to explore other options for specialty and infusion pharmacy software. Streamline pharmacy operations and improve clinical performance with automated processing, real-time data exchange, and electronic decision support. Download this helpful infographic to: Drive efficiency and patient adherence from referral receipt to delivery and ongoing care – all with our Pharmacy Cloud.

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VALIANT phase 3 trial results highlight potential treatment for rare kidney diseases

Pharmafile

SOBI and Apellis Pharmaceuticals have announced the results from the VALIANT trial, which highlight that systemic pegcetacoplan treatment could benefit patients with C3 glomerulopathy (C3G) and primary immune complex membranoproliferative glomerulonephritis (IC-MPGN). The VALIANT trial is a double-blind, randomised, multi-centre and placebo-controlled study that aimed to evaluate the efficacy and safety of pegcetacoplan in 124 […] The post VALIANT phase 3 trial results highlight potential

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GSK invests $800M in manufacturing; Amgen sets small discount for Eylea biosimilar

BioPharma Dive

The British pharma is making what it calls its largest U.S. manufacturing investment. Elsewhere, AbbVie expanded a longstanding partnership and Marinus said it would lay off staff.

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Shawn Cross appointed as chief financial officer for Pacira Biosciences

Pharmafile

Pacira Biosciences, spcecialist in non-opioid pain therapies, has appointed Shawn Cross as their chief financial officer. In this role, Mr Cross will take over all responsibility for the company’s financial operations. “I am proud to join Pacira as I am strongly aligned with the company’s important mission to deliver innovative, non-opioid pain therapies.

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Sanofi earnings boosted by Beyfortus, earlier vaccine sales

BioPharma Dive

Sanofi and partner AstraZeneca recently increased production capacity for their RSV antibody shot, sales of which jumped during the third quarter.

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From molecule to market and beyond: Uniphar announces extended global commercialization platform

Pharmafile

22 October 2024 – Dublin, Ireland – Healthcare services business, Uniphar, has developed its full-service offering that harnesses Uniphar’s 55 years in the industry delivering specialist services to more than 200 international clients across 180 countries. Combining Uniphar’s established expertise and tailored strategies, the platform is designed to support pharmaceutical and biotech companies navigate the […] The post From molecule to market and beyond: Uniphar announces extended global c

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