Tue.May 28, 2024

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STAT+: Gene therapies for deafness dredge up an old question: Do deaf people want a ‘cure’?

STAT

When Yilai Shu was training to be an otolaryngologist in Shanghai, in the mid 2000s, he often met parents with congenitally deaf kids. “They always asked me, ‘Do you have any drugs to treat our kids?’ said Shu, who is hearing and a professor at Fudan University in China. “That’s what really inspired me to think about developing a drug.

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As weight loss booms, drugmakers look for an edge with oral options

PharmaVoice

Supply of GLP-1 medications falls well short of demand, and oral versions of the drugs loom over Eli Lilly and Novo Nordisk’s dominance.

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Trending Sources

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At Las Vegas conference, methadone clinics blast idea of doctors prescribing directly

STAT

LAS VEGAS — Mark Parrino, the longtime leader of the U.S. methadone clinic industry, kicked off his organization’s conference here last week with a simple message: Allowing addiction doctors to prescribe the medication directly to their patients is “not a good idea.”  It was a revealing warning both in timing and tone.

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Early spike in demand for insect bites advice, suggests NHSE

The Pharmacist

Visits to the NHS England (NHSE) insect bites and stings web page were three times higher in the first three weeks of this month than in the same time period last year, suggesting an early spike in interest, a deputy chief nursing officer (CNO) has said. According to NHSE, the page received a total of […] The post Early spike in demand for insect bites advice, suggests NHSE appeared first on The Pharmacist.

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From Payroll Pains to Growth Gains: Streamlining Payroll & HR for Success

Speaker: Joe Sharpe and James Carlson

In the world of small business management, the challenge of managing payroll & HR efficiently while scaling operations can be overwhelming. Yet, with the right strategies in place, these challenges can become opportunities for growth and innovation. In this session, Joe Sharpe, Senior Director of Managed Payroll Services at IRIS, will reveal practical methods and expert insights for outsourcing and streamlining payroll processes, resulting in substantial time and resource savings.

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Heat waves associated with increased risk of preterm birth in the U.S.

STAT

Heat waves are becoming more frequent and more intense, posing more of a health risk around the world. High temperatures can be deadly, and are especially dangerous for those with cardiovascular and chronic disease — but they begin affecting human lives even before birth. Several studies have identified an increased risk of preterm delivery and stillbirth after heat exposure around the world.

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Lignin-based drug delivery system may improve chemotherapeutics

European Pharmaceutical Review

Researchers have defined the conditions to formulate novel polyelectrolyte complexes (PECs) based on a sustainable hemicellulose-rich lignosulphonate. Their findings suggest potential applications in drug delivery. Novel biomaterials based on PECs are being investigated in the industry as drug delivery systems, due to PECs being able to “to entrap drugs under mild conditions and control their release”.

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AI is coming and regulators are getting prepared

pharmaphorum

The rise of AI is shaking up the healthcare industry. Learn how the MHRA is working to ensure the safe and effective use of AI in drugs and medical devices.

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Opinion: Achieving telehealth equity for people with hearing loss

STAT

Gen Z has made captioning cool. Captions are now widely available in social media, entertainment channels, and web conferencing platforms, including YouTube, Hulu, and Zoom. Yet, there is one extremely important place where captions are not regularly available: telehealth visits. This disproportionately affects people with hearing loss. A friend of ours with hearing loss, whom we will call Cheryl, recently told us about her disappointing telehealth visit.

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Ampoules packaging market forecast to 2033

European Pharmaceutical Review

A report by The Brainy Insights has predicted that the ampoules packaging market will value $9.83 billion by 2033. This is expected to be largely driven by increasing demand for this packaging type. A higher incidence of chronic diseases will propel growth of the market between 2024 and 2033, according to the data. Prospects of the ampoules packaging market On the other hand, advancements in ampoule packaging, as well as sustainability measures and manufacturing innovations such as automation an

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STAT+: Airway disease drug from Insmed succeeds in one of the year’s most anticipated trials

STAT

An experimental drug from Insmed Incorporated successfully reduced lung problems among patients with an airway disease in a closely watched Phase 3 trial, sending the company’s share price soaring early Tuesday.   The drug, brensocatib, reduced so-called pulmonary exacerbations by roughly 20% versus placebo in patients with bronchiectasis, hitting the trial’s primary endpoint.

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Enhance Healthcare Efficiency With Top Payroll & HCM Services

Running a healthcare facility requires precision and care, not just for patients but also for your staff. Our guide, "A Buyer’s Guide to Payroll & HCM Services," helps healthcare providers choose the best provider. Efficient payroll management ensures timely, accurate payments, critical for maintaining staff morale and trust. Compliance support helps navigate complex healthcare regulations and avoid costly fines.

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MRC awards two medical research units at University of Cambridge £30m in funding

Pharma Times

The MRC BRC and the MDU will use the funding and cutting-edge research to improve public health until March 2029

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STAT+: Japanese conglomerate to buy Calliditas Therapeutics, maker of a kidney disease drug

STAT

LONDON — Seeking to build up its pharma business, the Japanese conglomerate Asahi Kasei is moving to buy Swedish biotech Calliditas Therapeutics in a nearly $1.1 billion cash deal, the companies said Tuesday.   The firm’s offer of $19.68 per share amounts to an 83% premium versus Calliditas’ closing price on a Swedish exchange Monday.

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CG Oncology Reveals Promising Results from Phase II CORE-001 Clinical Trial for the Treatment of BCG-Unresponsive High-Risk Non-Muscle Invasive Bladder Cancer

Pharmaceutical Commerce

Results from the CORE-001 clinical trial are expected to be presented at the American Society of Clinical Oncology (ASCO) 2024 Annual Meeting.

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STAT+: Pharmalittle: We’re reading about the Cencora data breach, a failed pandemic treaty, and more

STAT

Good morning, everyone, and welcome to another working week. We hope the weekend respite — which was extended on this side of the pond thanks to a holiday — was relaxing and invigorating. Now, though, the time has come to resume the usual routines of online meetings, phone calls, and what-not. After all, the world continues to spin, although it remains a bit wobbly where we are after losing a Pharmalot ancestor, which explains our recent disappearance.

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Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

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Bicycle Therapeutics secures $555M in private placement equity financing

Outsourcing Pharma

This funding round includes participation from both new and existing accredited investors, reinforcing confidence in Bicycle's innovative approach to precision-guided therapeutics.

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Biotech’s most interesting fundraisings from the last week

STAT

Want to stay on top of the science and politics driving biotech today?  Sign up  to get our biotech newsletter in your inbox. Hi, biotech friends. As we gear up for ASCO, we cogitate on some interesting questions. For instance: Gene therapy carries great potential to cure certain forms of congenital deafness, but does the community actually want that?

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LifeArc and ALS TDI announce partnership to develop new clinical tools for ALS and MND

Pharma Times

The project will validate two minimally invasive biomarkers for ALS: MMP-9 and TIMP-1

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ASCO 2024: the latest in cancer research

STAT

The ASCO annual meeting is widely considered one of the largest and most prestigious cancer research conferences in the world. From May 31-June 4, more than 40,000 oncology professionals will gather in Chicago for an event featuring 200 professional sessions and the presentation of more than 5,000 abstracts. STAT will host a kickoff event May 31, featuring top experts in oncology, and will offer a live wrap-up broadcast on June 5.

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5 Reasons to Upgrade Your Pharmacy Management Software

Are you still using workarounds to manage your daily operations? To achieve peak performance, it's time to explore other options for specialty and infusion pharmacy software. Streamline pharmacy operations and improve clinical performance with automated processing, real-time data exchange, and electronic decision support. Download this helpful infographic to: Drive efficiency and patient adherence from referral receipt to delivery and ongoing care – all with our Pharmacy Cloud.

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Pharmacists across primary care want next government to support community pharmacy

The Pharmacist

EXCLUSIVE Pharmacists across primary care are united in wanting support for community pharmacy to be a top priority for the next government, our snapshot survey has suggested. For pharmacists across general practice and community, support for community pharmacy ranked as a high priority issue, alongside better pay for all NHS staff. The 100 pharmacists across […] The post Pharmacists across primary care want next government to support community pharmacy appeared first on The Pharmacist.

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FDA accepts Sanofi’s Sarclisa sBLA for priority review

Pharmaceutical Technology

The US FDA has accepted for priority review Sanofi's sBLA for Sarclisa regimen for transplant-ineligible newly diagnosed multiple myeloma.

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Trial readout sets up filings for Insmed bronchiectasis drug

pharmaphorum

Shares in Insmed double as phase 3 trial sets up filings for brensocatib, aiming to become the first approved drug for bronchiectasis

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QUT team receives US DoD funding for Parkinson’s treatment

Pharmaceutical Technology

Scientists of QUT have secured A$4m ($2.65m) grant from the US DoD for developing new treatments for Parkinson's disease.

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HealthWell Foundation Unveils Fund to Help Patients Living with MASH

Pharmaceutical Commerce

Among its benefits, the fund will provide up to $8,000 in medication copayment or insurance premium assistance.

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Ex-Jazz, Sunesis exec Swisher takes over at NodThera

pharmaphorum

NLRP3-focused biotech NodThera has named former Jazz Pharma and Sunesis executive Dan Swisher as its new CEO.

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Agios cashes in on cancer drug again with $905M Royalty Pharma deal

BioPharma Dive

The deal involves royalties for a brain cancer drug Agios previously sold off and that Royalty Pharma thinks could generate more than $1 billion in U.S. sales.

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Parental permission, child assent, and adolescent autonomy in clinical research

pharmaphorum

Navigating the ethical landscape of clinical research with minors: exploring the HHS and FDA regulations around parental permission, child assent, and adolescent autonomy under CFR 46. Learn how to ethically and legally involve young participants in studies.

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Insmed shares double as lung drug data convince Wall Street

BioPharma Dive

After reporting positive clinical trial results for its drug brensocatib, Insmed plans to later this year file for U.S. approval in bronchiectasis that’s not associated with cystic fibrosis.

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Atropos Health secures $33M series B funding to enhance generative AI in healthcare

Outsourcing Pharma

Atropos Health announced last week the successful completion of its $33 million Series B funding round.

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Roche’s Sabry retires; Duchenne drug fails confirmatory test

BioPharma Dive

The veteran executive will be replaced by Boris Zaïtra. Elsewhere, Nippon Shinyaku shared negative Phase 3 data and Merck unveiled new breast cancer results for Keytruda.

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RevolKa signs deal with Daiichi Sankyo for functional proteins

Pharmaceutical Business Review

Under the terms of the agreement, RevolKa will utilise its protein engineering platform, aiProtein, integrated with artificial intelligence (AI), to create and deliver highly functional proteins. The companies did not disclose the financial details of the deal. aiProtein is an AI-powered method for the directed evolution of proteins. Proteins, which are naturally occurring polymers of amino acids, fold into complex tertiary structures to exhibit biological functions.

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The future of medicine: AI’s role in uncovering new drugs

BioPharma Dive

Artificial intelligence (AI) has sparked a revolution in the pharmaceutical industry, reshaping the way we approach complex biological challenges.

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Eli Lilly increases manufacturing investment to $9bn at new Indiana site

Pharmafile

Eli Lilly has announced that it has more than doubled its investment at its Lebanon, Indiana, US manufacturing site with a new $5.3bn investment, totalling its investment at this site to $9bn from its original $3.7bn. The post Eli Lilly increases manufacturing investment to $9bn at new Indiana site appeared first on Pharmafile.

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Swixx BioPharma expands to Latin America through strategic acquisition of Biopas

Outsourcing Pharma

Swixx BioPharma AG, a platform dedicated to unlocking access to e medicines, has announced its strategic expansion into Latin America.

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