Fri.May 17, 2024

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STAT+: Data integrity watchdogs call for stronger safeguards in scientific journals

STAT

SAN FRANCISCO — According to Elisabeth Bik, a scientific watchdog who has discovered thousands of errors in scientific papers, the problem of fraud, errors, or data mishandling in the scientific literature seems to be getting worse. In the last couple of years, Bik’s been seeing an influx of AI-generated papers in the scientific record that are “nonsensical and clearly low quality.

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Why H5N1 has scientists and regulators on edge

PharmaVoice

The strange — and difficult — aspects of the recent influenza outbreak in cattle and its potential threat to humans.

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Animal studies lend support to an innovative HIV vaccine strategy — but there’s still a long way to go

STAT

HIV has long stumped immunologists looking to develop an effective vaccine. All of the most promising approaches pioneered in the past three and a half decades have ultimately failed, and only a few months ago, the last trial expected to potentially deliver a vaccine within this decade was shut down. But HIV scientists are nothing if not resilient, and used to trying one new approach after another.

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Hub and spoke discussions in Scotland won’t start until funding agreed, says CPS

The Pharmacist

Community pharmacy negotiators in Scotland will not begin conversations about how new hub and spoke legislation will affect NHS dispensing until the sector has its funding in place for 2024/25, Community Pharmacy Scotland (CPS) has confirmed to The Pharmacist. Meanwhile, negotiators in Northern Ireland have expressed disappointment that the government has proceeded with the spoke-hub-patient […] The post Hub and spoke discussions in Scotland won’t start until funding agreed, says CPS appea

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From Payroll Pains to Growth Gains: Streamlining Payroll & HR for Success

Speaker: Joe Sharpe and James Carlson

In the world of small business management, the challenge of managing payroll & HR efficiently while scaling operations can be overwhelming. Yet, with the right strategies in place, these challenges can become opportunities for growth and innovation. In this session, Joe Sharpe, Senior Director of Managed Payroll Services at IRIS, will reveal practical methods and expert insights for outsourcing and streamlining payroll processes, resulting in substantial time and resource savings.

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STAT+: ChatGPT for genomes: introducing a CRISPR-designing generative AI

STAT

In 2018, during her chemistry Nobel Prize lecture, Frances Arnold noted that scientists had arrived at a point where they could read, write, and edit any sequence of DNA. But composing whole genes or even whole genomes from scratch — that was something only evolution could do. A few years later, not long after helping to launch the Arc Institute, a nonprofit research center in the Bay Area, molecular engineer Patrick Hsu wondered if it was possible to imitate the forces of evolution

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FDA approves Amgen’s Imdelltra for extensive-stage small cell lung cancer

Pharmafile

Amgen has announced that the US Food and Drug Administration (FDA) has approved Imdelltra (tarlatamab-dlle) for the treatment of adult patients with extensive-stage small cell lung cancer (ES-SCLC) who have had disease progression on or after platinum-based chemotherapy. The post FDA approves Amgen’s Imdelltra for extensive-stage small cell lung cancer appeared first on Pharmafile.

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Lung disease imaging AI from Brainomix gets FDA nod

pharmaphorum

Brainomix gets FDA approval for e-Lung, an AI tool that assists in the diagnosis and assessment of patients with interstitial lung diseases (ILDs) from medical images.

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Opinion: Hurricane season is approaching fast. We need to talk about health care resilience

STAT

Extreme weather fueled by accelerating climate change puts patients, providers, and health care facilities at severe risk, jeopardizing lives. Unpredictable shifts in weather patterns are creating new regional extremes , and communities have to adjust to survive. During climate crises, health care providers and facilities must be ready to quickly adapt to shifting needs.

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Liverpool and McMaster University announce £300,000 institutional strategic research partnership

Pharma Times

Areas include health research across life stages, from paediatrics to health ageing and resilience

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STAT+: Wearable devices generate powerful data but it’s not useful to doctors, yet

STAT

Just because the Food and Drug Administration has given the Apple Watch and other wearable devices the OK to market the health benefits of their tracking and algorithms doesn’t mean that the data they generate are useful for either patients or their doctors, experts said Thursday at the STAT Breakthrough Summit West in San Francisco. “Yesterday, I saw a patient with type 2 diabetes who has a continuous glucose monitor, and so she’s been tracking her blood sugar every five mi

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Enhance Healthcare Efficiency With Top Payroll & HCM Services

Running a healthcare facility requires precision and care, not just for patients but also for your staff. Our guide, "A Buyer’s Guide to Payroll & HCM Services," helps healthcare providers choose the best provider. Efficient payroll management ensures timely, accurate payments, critical for maintaining staff morale and trust. Compliance support helps navigate complex healthcare regulations and avoid costly fines.

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GLP-1R agonists’ type 2 diabetes and obesity market to reach $125 billion in 7MM by 2033: GlobalData

Express Pharma

Glucagon-like peptide-1 (GLP-1) receptor agonists are a class of incretin mimetic medicines for the treatment of type 2 diabetes and obesity. With the obesity and type 2 diabetes markets growing at unprecedented rates, the GLP-1 receptor agonists market is also growing. GLP-1 receptor agonist sales for the type 2 diabetes and obesity markets are forecast to reach over $125 billion in the seven major markets (7MM*) by 2033, according to GlobalData.

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STAT+: To bolster global health, Wellcome Trust’s new CEO thinks Big Tech should get involved

STAT

LONDON — The key groups involved in addressing global health problems often include governments, foundations, and pharmaceutical companies. But to John-Arne Røttingen, the new head of the Wellcome Trust , one of the world’s top private funders of biomedical research, there’s another sector that should be getting involved — the tech industry.

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A greener catalysis: Talking sustainable, scalable chemistry with KCL

pharmaphorum

Explore sustainable catalysis and its potential to transform chemical reactions in drug discovery. Learn how green chemistry plays a pivotal role in shaping the future of catalysis.

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STAT+: Venture capitalist Bob Kocher on generative AI startups, Change Healthcare cyberattack

STAT

SAN FRANCISCO — Health tech investor Bob Kocher has seen some bad AI-related startup pitches in his time. The worst typically involve AI chatbots masquerading as romantic partners to improve people’s mental health. “They pitch it to me as a mental health improvement model,” Kocher, a partner at venture capital firm Venrock, said.

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Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

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Pharmacy First: No plans to replace referral requirement with walk-in approach

The Pharmacist

There are currently no plans to replace the referral requirement of Pharmacy First with a walk-in approach, NHS England (NHSE) has suggested. At the Clinical Pharmacy Congress last week, NHSE’s clinical strategy for community pharmacy lead Pallavi Dawda confirmed that it was not considering removing the need for a GP referral for minor illnesses and […] The post Pharmacy First: No plans to replace referral requirement with walk-in approach appeared first on The Pharmacist.

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STAT+: Amid acquisition speculation, Cytokinetics CEO stresses company can launch heart drug on its own

STAT

As Cytokinetics faces pressure to sell itself to a large pharma company following positive late-stage results of its heart drug, CEO Robert Blum maintains that the biotech can launch the treatment — what would be its first approved medication — on its own. Cytokinetics reported top-line results of its drug, aficamten, in obstructive hypertrophic cardiomyopathy, or oHCM, last December, sending its shares up on speculation the company would get acquired.

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FDA approves Amgen T-cell engager for small cell lung cancer

European Pharmaceutical Review

The US Food and Drug Administration (FDA) has approved Amgen’s Imdelltra (tarlatamab-dlle), a bispecific T-cell engager, for the treatment of adult patients with extensive-stage small cell lung cancer (ES-SCLC). The drug received accelerated regulatory approval based on the “encouraging response rate and duration of response (DoR) observed in clinical studies,” Amgen said.

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STAT+: Pharmalittle: We’re reading about an Amgen drug for lung cancer, a Novo plant fire, and more

STAT

And so, another working week will soon draw to a close. Not a moment too soon, yes? This is, you may recall, our treasured signal to daydream about weekend plans. Our agenda is still shaping up, but we expect to promenade with the official mascots, take in a moving picture, and hold another listening party, where the rotation will likely include this , this , this , this and this.

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5 Reasons to Upgrade Your Pharmacy Management Software

Are you still using workarounds to manage your daily operations? To achieve peak performance, it's time to explore other options for specialty and infusion pharmacy software. Streamline pharmacy operations and improve clinical performance with automated processing, real-time data exchange, and electronic decision support. Download this helpful infographic to: Drive efficiency and patient adherence from referral receipt to delivery and ongoing care – all with our Pharmacy Cloud.

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Effective data quality governance: challenging five common myths

European Pharmaceutical Review

Everything in the pharmaceutical industry now seems to rely increasingly heavily on effective organisation and handling of data. But what needs to happen so that users/process owners can fully trust data’s quality, integrity, reliability, etc? Steve Gens (SG): The more critical data becomes to regulatory procedures, to safety processes, to clinical research, to manufacturing, and ultimately connecting all of those parts of the value chain more seamlessly, the greater the need for formal and cons

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AstraZeneca antibody reduced Covid-19 risk in immunocompromised

STAT

Want to stay on top of the science and politics driving biotech today?  Sign up  to get our biotech newsletter in your inbox. Asking again! Could you tell us what you think of The Readout? Fill out this  survey !

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EMA recommends suspension of hydroxyprogesterone caproate medicines

European Pharmaceutical Review

EMA’s Pharmacovigilance Risk Assessment Committee (PRAC) has recommended the suspension of the marketing authorisations for medicines containing 17-hydroxyprogesterone caproate (17-OHPC) in the European Union. The recommendation follows a review by the PRAC , which concluded that there is a “possible but unconfirmed risk of cancer in people exposed to 17-OHPC in the womb.

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STAT+: Up and down the ladder: The latest comings and goings

STAT

Hired someone new and exciting? Promoted a rising star? Finally solved that hard-to-fill spot? Share the news with us, and we’ll share it with others.  That’s right. Send us your changes, and we’ll find a home for them. Don’t be shy. Everyone wants to know who is coming and going. And here is our regular feature in which we highlight a different person each week.

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Sanders issues warning to Novo Nordisk amid GLP-1 drug price investigation

Pharmaceutical Technology

The US Senator took another swipe at the US prices of Novo Nordisk’s blockbuster GLP-1 receptor agonist drugs Ozempic and Wegovy.

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Overcoming challenges with maternal vaccine trials

pharmaphorum

Navigating maternal vaccine trials: addressing safety, efficacy, and preterm birth risks. Insights on vaccines for pregnant women and maternal health.

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Study finds link between malaria parasites developing antimalarial drug resistance

Pharma Times

The mosquito-borne disease affected around 249 million people globally in 2022

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Pharma Pulse 5/17/24: Apple Watch's Afib App certified by FDA, Learning Telehealth Platforms Benefits Pharmacy Students & more

Pharmaceutical Commerce

Business strategies and top news in the biotech / biopharma industry, including market access, supply chain distribution and more.

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Glenmark receives ANDA approval for Brimonidine Tartrate and Timolol Maleate Ophthalmic Solution, 0.2%|0.5%

Express Pharma

Glenmark Pharmaceuticals has received final approval by the USFDA for Brimonidine Tartrate and Timolol Maleate Ophthalmic Solution, 0.2%|0.5%. Glenmark’s Brimonidine Tartrate and Timolol Maleate Ophthalmic Solution, 0.2%|0.5% has been determined by the FDA to be bioequivalent and therapeutically equivalent (1) to Combigan (2) Ophthalmic Solution, 0.2%|0.5%, of AbbVie, and will be distributed in the US by Glenmark Pharma Inc., USA.

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Amgen adds BiTE to its cancer range as FDA clears Imdelltra

pharmaphorum

Amgen gets FDA approval for Imdelltra as a treatment for small cell lung cancer, becoming the first DLL3-targeted drug and the company's second BiTE therapy.

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Growth Guardians | Sailesh Sigatapu, General Partner at Anthill Ventures

Express Pharma

In this special edition of the Express Pharma-NutrifyToday Boardroom Series, we introduce you to Sailesh Sigatapu, Partner, Anthill Ventures, one of the six Growth Guardians who will judge the merit of the contestants during the Nutrify C Suite Sumflex – Innovation Battlefield. Sigatapu leads fundraising and investor relations for Anthill Ventures, leveraging nearly two decades of experience, particularly in sustainability and green building technology.

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J&J reels in bispecific specialist Proteologix in $850m deal

pharmaphorum

Johnson & Johnson has agreed a $850m deal to acquire Proteologix that will give it a pair of early-stage bispecific antibodies for atopic dermatitis and asthma.

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Biogen, Ionis terminates development of ALS investigational drug

Express Pharma

Biogen and Ionis Pharmaceuticals announced the decision to terminate development of BIIB105 (ION541) an investigational antisense oligonucleotide (ASO) for amyotrophic lateral sclerosis (ALS) based on topline results from the Phase 1/2 ALSpire study. BIIB105 was designed to reduce expression of ataxin-2 (ATXN2) protein and demonstrated statistically significant cerebrospinal fluid (CSF) ATXN2 protein reductions in the study.

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AI-powered WhatsApp messaging cleared for NHS pilot

pharmaphorum

An artificial intelligence-driven WhatsApp messaging platform for scheduling cervical cancer screening appointments is being piloted in London to see if it can improve take-up rates. The pilot of the Asa AI assistant – cleared by the NHS North Central London Integrated Care Board (ICB) – will take place at the Islington GP Federation in London.

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Exploring Multimodal Biomanufacturing and Its Drivers

PharmaTech

A combination of rapid sterility methods with the industry standard compendial method should ensure maximum safety.

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