Wed.Jul 10, 2024

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Researchers identify ‘molecular switch’ in lupus that could stymie harmful immune response

STAT

Lupus, in superhero terms, tells a devastating story. A loyal hero turns villain and works to destroy his own people. But new research asks the question: What if immune cells could be turned back into good guys, and actually help save tissue damaged by autoimmune disease?  Lupus is complicated because it wields the body’s own defenses against itself, generating a continuous immune misfire.

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Pfizer research chief Dolsten to step down, with company at a crossroads

PharmaVoice

The company has begun searching for a successor to Dolsten, who oversaw more than 35 drug and vaccine approvals alongside notable setbacks during his time as Pfizer’s top scientist.

Vaccines 245
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Trending Sources

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STAT+: FTC plans to sue PBMs over the high cost of insulin and other medicines

STAT

The U.S. Federal Trade Commission plans to sue the three largest pharmacy benefit managers over their negotiating tactics for various medicines, including insulin, that pushed patients toward higher-priced treatments, according to a source familiar with the matter. The step comes after the agency this week released a scathing report that found the three largest PBMs — Express Scripts, Caremark, and OptumRx — processed nearly 80% of the roughly 6.6 billion prescriptions that were di

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As the GLP-1 market booms, other healthcare companies are cashing in

PharmaVoice

As more Americans take obesity medications, adjacent businesses are offering supportive services to offset side effects, collect data and foster new health benefits.

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From Payroll Pains to Growth Gains: Streamlining Payroll & HR for Success

Speaker: Joe Sharpe and James Carlson

In the world of small business management, the challenge of managing payroll & HR efficiently while scaling operations can be overwhelming. Yet, with the right strategies in place, these challenges can become opportunities for growth and innovation. In this session, Joe Sharpe, Senior Director of Managed Payroll Services at IRIS, will reveal practical methods and expert insights for outsourcing and streamlining payroll processes, resulting in substantial time and resource savings.

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Free medical school tuition unlikely to have a major impact on the U.S. health care system

STAT

Most of Johns Hopkins University’s medical school students will have free tuition starting this fall, thanks to a $1 billion gift from Bloomberg Philanthropies, a longtime donor of the university, whose school of public health is named after Michael Bloomberg. The largesse is striking, but, even combined with other recent moves to relieve future doctors of crushing medical debt, the move may not reverberate to bring improvements to the broader health care system, experts say.

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Streeting looks to healthcare to provide economic boost for UK

The Pharmacist

The health sector can be a source of economic growth rather than government expenditure, according to new health and social care secretary Wes Streeting. Speaking at an event for the Tony Blair Institute for Global Change, Mr Streeting said his ambition was to ‘end the begging bowl culture’ where the Department of Health and Social […] The post Streeting looks to healthcare to provide economic boost for UK appeared first on The Pharmacist.

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Turning pilots into production: How to create, scale, and succeed with GenAI

pharmaphorum

Learn how to successfully transition pilots into production with GenAI in the pharmaceutical industry. Discover strategies to create, scale, and achieve success with this innovative technology.

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STAT+: VC Flagship Pioneering raises $3.6 billion in new funds

STAT

Flagship Pioneering, one of the largest firms investing in and creating new biotech companies, said Wednesday that it has raised $3.6 billion in new funding. The Cambridge, Mass.-based organization raised $2.6 billion for Flagship Pioneering Fund VIII, as well as $1 billion for what it described as side funds and sector-specific strategic partnerships.

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Three-quarters of GP pharmacists plan to stay in practice

The Pharmacist

Almost three-quarters (72%) of primary care pharmacists and pharmacy technicians say they can see themselves working in the same GP practice in five years' time, a snapshot survey has shown. In the same survey, pharmacy teams generally reported high levels of job satisfaction, often exceeding other direct patient care roles within general practice. Around 100 […] The post Three-quarters of GP pharmacists plan to stay in practice appeared first on The Pharmacist.

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STAT+: Novo Nordisk’s weekly insulin rejected by FDA

STAT

The Food and Drug Administration rejected Novo Nordisk’s weekly insulin for the treatment of diabetes in a rare setback for the pharmaceutical giant. The agency has requests related to the manufacturing process and the use of the insulin specifically in type 1 diabetes patients, Novo said in a statement Wednesday. The company, which had submitted an application for the drug for both type 1 and type 2 patients, said it does not expect to be able to fulfill the requests this year.

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Enhance Healthcare Efficiency With Top Payroll & HCM Services

Running a healthcare facility requires precision and care, not just for patients but also for your staff. Our guide, "A Buyer’s Guide to Payroll & HCM Services," helps healthcare providers choose the best provider. Efficient payroll management ensures timely, accurate payments, critical for maintaining staff morale and trust. Compliance support helps navigate complex healthcare regulations and avoid costly fines.

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UK DRI and NHS collaborate on digitally enabled dementia care platform

Pharma Times

Around one in five dementia hospitalisations are due to potentially preventable causes

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STAT+: Biden administration ignores calls to bolster hospital price transparency

STAT

The federal government will not modify regulations that dictate how hospitals publish their prices for consumers, ignoring pleas from patient advocates who have said hospitals still are not fully complying with the 3-year-old law. The Biden administration on Wednesday proposed an annual rule that sets payment rates for hospitals. This document is where the government has in the past rolled out changes to the so-called hospital price transparency rule, but the Biden administration did not address

Hospitals 281
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Pharmacy bodies pen letter to new health secretary calling for urgent funding

The Pharmacist

Reform and investment in community pharmacy can help address the issue of waiting times for GP and hospital appointments, a group of industry bodies have told the new health and social care secretary. In a joint letter seen by The Pharmacist, Community Pharmacy England, the Company Chemists’ Association, the Independent Pharmacies Association, the National Pharmacy […] The post Pharmacy bodies pen letter to new health secretary calling for urgent funding appeared first on The Pharmacist.

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Opinion: Expand community-based research to make clinical trials more diverse

STAT

Innovations in clinical trial designs and tools have the potential to unlock a new era of research that is more convenient for patients, more reflective of real-world treatment conditions, and more likely to enable participation of a diverse set of individuals. But a recent study reveals how far the U.S. is from realizing this potential: regions of the country with the worst social drivers of health are the least likely to host clinical trials.

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Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

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The Current Landscape of Drug Shortages

Pharmaceutical Commerce

In an interview with Pharma Commerce editor Nicholas Saraceno, Peter Ax, UpScriptHealth, founder and CEO, offers his thoughts surrounding the lack of supply.

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STAT+: Pharmalittle: We’re reading about biopharma layoffs, Purdue bankruptcy talks, and more

STAT

Hello, everyone, and how are you today? We are doing just fine, thank you, especially since the middle of the week is upon us. After all, we have made it this far, so we are determined to hang on for another couple of days. And why not? The alternatives — at least those we can identify — are not so appetizing. And what better way to make the time fly than to keep busy.

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After FDA delay, Arcutis gets Zoryve OK in atopic dermatitis

pharmaphorum

After short but worrying delay, Arcutis gets FDA approval for flagship drug Zoryve in atopic dermatitis, which could further unlock sales growth

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STAT+: Sanford Health aims to shake off a run of failed deals by snapping up a $3 billion Wisconsin health system

STAT

Fourth time’s the charm? Sanford Health is hoping so. Less than a year after scrapping its proposed merger with a Minnesota health system — its third failed deal since 2019 — South Dakota’s Sanford is attempting a new, multibillion-dollar mashup. The $7 billion, 45-hospital system plans to absorb Marshfield Clinic Health System, a $3 billion system of 11 hospitals across Wisconsin and northern Michigan.

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5 Reasons to Upgrade Your Pharmacy Management Software

Are you still using workarounds to manage your daily operations? To achieve peak performance, it's time to explore other options for specialty and infusion pharmacy software. Streamline pharmacy operations and improve clinical performance with automated processing, real-time data exchange, and electronic decision support. Download this helpful infographic to: Drive efficiency and patient adherence from referral receipt to delivery and ongoing care – all with our Pharmacy Cloud.

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Healey platform data to pave phase III path for Prilenia’s pridopidine: GlobalData

Express Pharma

Developing disease-modifying treatments for amyotrophic lateral sclerosis (ALS), a rare and aggressive disease, has proven challenging. The high failure rate in ALS clinical trials is often attributed to the disease’s unclear etiology and complex pathophysiology. At the 10th Congress of the European Academy of Neurology (EAN) 2024, Prilenia Therapeutics presented promising results from the additional analyses of the Phase II Healey ALS Platform Trial evaluating pridopidine in ALS patients.

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uniQure shares soar on Huntington’s data

STAT

Want to stay on top of the science and politics driving biotech today?  Sign up  to get our biotech newsletter in your inbox. Good morning. It’s been a challenging time for workers in the biopharma industry. We’ve seen companies announce layoffs one after another, and people online talk about how it seems increasingly difficult to secure a new job.

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Prioritised investments from pharma companies shaping competitive pipeline landscape of bronchiectasis: GlobalData

Express Pharma

Recent studies have allowed the unexplored field of bronchiectasis to be further investigated by shedding light on the mechanisms behind the disease’s pathophysiology. In recent years, bronchiectasis has garnered a significant amount of attention, with pharmaceutical companies prioritising their investments in the development of promising pipeline agents to treat the disease through various mechanisms of action (MOAs).

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Overcoming barriers to opioid treatment: Challenges and innovations in methadone and buprenorphine

Outsourcing Pharma

The growing opioid crisis in the US has been exacerbated by various systems and biases, preventing individuals from accessing critical treatments like methadone and buprenorphine.

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Viagra’s Resilience in the Face of Generic Competition: A Pharmaceutical Market Analysis

Drug Patent Watch

This is an example from the DrugPatentWatch AI Research Assistant, which is available with DrugPatentWatch subscriptions.

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Institutions to lead £1.7m-funded network to support people at risk of dementia

Pharma Times

The neurodegenerative condition currently affects more than 944,000 people in the UK

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Delaying diabetes with diet and exercise for 4 years results in better long-term health

World Pharma News

Individuals diagnosed with prediabetes can reduce their long-term risk of death and diabetes-related health complications if they delay the onset of diabetes for just four years through diet and exercise. Guangwei Li of the China-Japan Friendship Hospital and colleagues report these findings in a new study published July 9th in the open-access journal PLOS Medicine.

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Emcure makes a premium of 31.5 per cent over IPO price

Express Pharma

Emcure Pharmaceuticals shares made a debut on July 10 after listing at Rs 1,325.05, a premium of 31.5 per cent over the issue price of Rs 1,008. The successful Initial Public Offering (IPO) gathered significant investor interest. Emcure’s IPO ran from July 3 to July 5 and is a book-built issue valued at Rs 1,952.03 crores. The price band per share was Rs 960- Rs 1008.

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NICE recommends Ebglyss for atopic dermatitis patients

Pharmaceutical Technology

Almirall’s Ebglyss is predicted to hit blockbuster status in two years in the crowded atopic dermatitis market.

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Top 3 Drugs That Change Urine Color

Med Ed 101

My pee is orange! What’s wrong with me? Medications can cause some goofy side effects. One of the most unique adverse effects is the change in urine color. In this blog post, I will outline my top 5 drugs that change urine color. Antibiotics That Change Urine Color Nitrofurantoin is an antibiotic used for the […] The post Top 3 Drugs That Change Urine Color appeared first on Med Ed 101.

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uniQure rockets on Huntington’s gene therapy result

pharmaphorum

Shares in Dutch biotech uniQure shoot up after Huntington’s candidate AMT-130 slows disease progression by 80% two years after dosing.

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Amylyx, with GLP-1 buy, doubles down on blood sugar drugs

BioPharma Dive

Having recently withdrawn its only product from the market, Amylyx hopes to rebound with a drug that regulates GLP-1 activity and is poised to enter pivotal testing early next year.

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The next frontier: Global leadership in biopharma

Express Pharma

India has traced a journey of grit and glory to emerge as a major supplier of generic drugs and vaccines globally. Today, it is a key player in the global pharma landscape. However, as healthcare demands and the life sciences landscape evolves, it is now time to conquer new frontiers and expand its horizons far beyond generics. With advancements in biotechnology, robust scientific capabilities, cost-effective manufacturing processes, a large workforce and a shift towards more complex biologic dr

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Evotec and Pfizer announce drug discovery collaboration

Pharmaceutical Technology

Evotec and Pfizer have entered a multi-year partnership that will focus initially on early discovery research.

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The State of Patient Support Services in Today’s Landscape

Pharmaceutical Commerce

Why these programs require a hybrid approach that combines technology and human connection.

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