Sun.Dec 08, 2024

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STAT+: BIOSECURE Act, aimed at Chinese drug manufacturers, is dealt a major blow

STAT

WASHINGTON — Legislation to restrict U.S. drugmakers from using key Chinese contract manufacturers was dealt a major blow when senators left it out of a must-pass defense budget bill this weekend. The BIOSECURE Act would prohibit pharmaceutical and biotechnology companies from using services or equipment from Chinese “companies of concern,” including WuXi AppTec and WuXi Biologics, in work that is contracted or funded by the U.S. federal government.

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Handling Drug Patent Invalidity Claims

Drug Patent Watch

The pharmaceutical industry is heavily reliant on patents to protect intellectual property and maintain market exclusivity. However, with the increasing competition from generic and biosimilar manufacturers, patent invalidity claims have become a significant challenge for pharmaceutical companies.

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STAT+: Pfizer’s abrupt withdrawal of sickle cell drug Oxbryta called ‘tone deaf’ at ASH conference

STAT

SAN DIEGO — Pfizer’s abrupt withdrawal of its sickle cell drug Oxybryta over safety concerns was called “tone deaf” during a panel discussion among sickle cell experts Saturday at STAT@ASH , which took place during the American Society of Hematology’s annual meeting. They said patients were despondent over how suddenly the drug was pulled from the market in September because there had been no clear indication of problems in advance of the announcement.

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M&A in pharma sees deals worth $14.8 bn, in Nov 2024

Express Pharma

In November 2024, the pharma and healthcare industry reported 95 deals worth $14.8 billion, compared to the last 12-month (November 2023 to October 2024) average of 102 deals worth $16.8 billion. Hoffmann-La Roche, to acquire Poseida Therapeutics, a clinical-stage allogeneic cell therapy and genetic medicine company for an equity value of $1.5 billion; Ampersand Capital Partners and GHO Capital Partners, to acquire Avid Bioservices, a biologics contract development and manufacturing organisation

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Navigating Payroll Compliance: Future-Proofing Payroll in an Evolving Regulatory Landscape

Speaker: Jennifer Hill

Payroll compliance is a cornerstone of business success, yet for small and midsize businesses, it’s becoming increasingly challenging to navigate the ever-evolving landscape of federal, state, and local regulations. Mistakes can lead to costly penalties and operational disruptions, making it essential to adopt advanced solutions that ensure accuracy and efficiency.

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Episode 981: Tranexamic Acid to Control Iatrogenic Bleeding During Flexible Bronchoscopy

Pharmacy Joe

In this episode, Ill discuss tranexamic acid for controlling iatrogenic bleeding during flexible bronchoscopy. Subscribe on iTunes , Android , or Stitcher While pharmacists are not typically present when a bronchoscopy takes place, medications are involved both to help the patient tolerate the procedure and to address issues that come up as a result of the procedure.

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ASHP: Identify and Counsel Patients at High Risk for Severe COVID-19

Pharmacy Times

By identifying patients at high risk for progressing to severe disease and counseling them on their treatment options, pharmacists empower patients to make informed decisions about their treatment.

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Integrating Advanced Technologies for Pharma Analysis

PharmaTech

Automation technologies provide real potential to improve responsiveness and decision-making in drug development.

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Fixed-Duration Acalabrutinib and Venetoclax Regimens Redefine First-Line Treatment Options for Patients With CLL

Pharmacy Times

The phase 3 AMPLIFY trial demonstrates that fixed-duration regimens of acalabrutinib and venetoclax, with or without obinutuzumab, significantly improve progression-free survival and deliver manageable safety profiles compared to chemoimmunotherapy in treatment-naive chronic lymphocytic leukemia (CLL).

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Study paints clearer picture of disadvantaged leukemia patients’ struggle to get bone marrow transplants

STAT

SAN DIEGO — Bone marrow transplants can be lifesaving for patients with acute myeloid leukemia, but new research reveals how socioeconomic factors create barriers to treatment and higher death rates for people living in disadvantaged communities. A scientific team led by researchers at Fred Hutchinson Cancer Center tracked AML patients across academic and community treatment centers.

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From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

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ASHP Midyear: Opioid Use Disorder in Critically Ill Patients Has Unique Challenges

Pharmacy Times

In hospital and critical care settings, pharmacists can play a significant role in educating other health care providers about treatment options, proper dosing, and more.

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Biopharma leaders lay out vision for the future of blood cancer treatment

STAT

(This roundup of news from the ASH 2024 conference first appeared in STAT’s “ASH in 30” newsletter. To get future editions,  sign up here.) When in San Diego, eat tacos. Amazing. Adam, Jonathan, Meghana, and Angus are back for your Sunday ASH rundown. And thanks to everyone who packed the room last night for our STAT @ ASH event.

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ASH 2024: Rapid Uptake of Bispecific Antibodies for R/R Multiple Myeloma Observed in Community Oncology Settings

Pharmacy Times

Ira Zackon, MD explains his analysis of bispecific antibody utilizaton for relapsed or refractory multiple myeloma in community oncology centers.

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The Sighing Christian

The Honest Apothecary

Rejoicing is a Christian duty and privilege. In fact, it is to be a perpetual ornament of the character of every believer in Christ Jesus. “Rejoice in the Lord always”, says Paul to the Philippians in chapter 4:4 of that epistle, “and again I say, rejoice!” And there is much for us to be joyful […] The post The Sighing Christian appeared first on The Honest Apothecary.

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Why Every Small Business Needs an HCM Solution: A Comprehensive Guide

Managing HR tasks like payroll, compliance, and employee data can overwhelm small businesses. That’s where a Human Capital Management (HCM) solution comes in. Our eBook, Why Every Small Business Needs an HCM Solution: A Comprehensive Guide , shows how an HCM system automates tedious processes, ensuring your business stays compliant and efficient. You’ll learn how to simplify payroll, eliminate costly errors, and empower your employees with self-service tools.

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ASHP Midyear: Pharmacists Play Key Role in Optimizing Continuous Glucose Monitoring for Diabetes Management

Pharmacy Times

Pharmacists can leverage continuous glucose monitoring data to personalize diabetes management, overcome clinical inertia, and improve glycemic control for patients.

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WHO sheds some light on factors possibly at play in DRC outbreak

STAT

The cause of an outbreak of illness in a remote part of the Democratic Republic of the Congo that has garnered substantial international attention is still not known. But a statement released Sunday by the World Health Organization both sheds some light on why the source of the illness hasn’t yet been identified and what the illness — or illnesses — might be.

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ASH: Zanubrutinib Demonstrates Long-Term Efficacy in Patients With Waldenström Macroglobulinemia

Pharmacy Times

Shirley D'Sa, MD, highlights the long-term efficacy and tolerability of zanubrutinib in patients with Waldenstrm macroglobulinemia, as seen in the long-term extension of ASPEN.

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Trump suggests he shares some of RFK Jr.’s concerns about childhood vaccines

STAT

President-elect Donald Trump suggested in a television interview on Sunday that he shares some of the concerns voiced by Robert F. Kennedy Jr., his choice to be secretary of health and human services, about the safety of some common childhood vaccines. The comments, made on NBC’s Meet the Press , represent an increased sign of support for RFK Jr. taking action on that topic if he is confirmed by the Senate.

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Best Practices to Streamline Compensation Management: A Foundation for Growth

Speaker: Joe Sharpe and James Carlson

Payroll optimization can be one of the most time-consuming and complex factors of small business management. Yet, organizations that crack the code on streamlining employee compensation often discover innovative avenues for growth. With the right strategies in place, outsourcing and streamlining payroll processes can result in substantial time and resource savings.

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ASH 2024: New Treatments in Trial Pipeline Show Promising Survival Rates in R/R Multiple Myeloma

Pharmacy Times

Robert Rifkin, MD, FACP, discusses multiple abstracts featuring drugs demonstrating efficacy in patients with relapsed/refractory multiple myeloma.

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Daratumumab Demonstrates Significant Benefit in High-Risk Smoldering Myeloma: Results from the Phase 3 AQUILA Study

Pharmacy Times

The AQUILA study demonstrates that early treatment with daratumumab significantly delays progression to symptomatic multiple myeloma, improves survival outcomes, and offers a well-tolerated alternative to traditional observation.

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ASHP Midyear: Expert Highlights New Non-Statin Medication and Combination Therapy Strategies

Pharmacy Times

Both statins and newer non-statin medications are important in combination to effectively lower atherogenic lipid levels and reduce cardiovascular risk.

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