Tue.Apr 30, 2024

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What we’re starting to learn about H5N1 in cows, and the risk to people

STAT

The H5N1 bird flu virus has been around for decades, and the damage it wreaks on chickens and other poultry is well documented. But the recent discovery that the virus has jumped into dairy cattle — whose udders seem to be where the virus either infects or migrates to — has dumbfounded scientists and agricultural authorities. Questions for which there are pretty clear answers when it comes to birds are suddenly unsettled science in cows.

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Cambridge study finds AI more accurately assesses eye problems compared to doctors

Pharma Times

GPT-4 is trained on datasets to offer eye-related advice, diagnosis and management suggestions

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Trending Sources

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With younger women getting breast cancer, national panel lowers mammogram screening age to 40

STAT

A national advisory panel significantly lowered the age recommendations for screening mammography on Tuesday, saying that all women should start breast cancer screening at age 40, rather than 50, and continue every other year until age 74. The previous recommendations from the panel, the United States Preventive Services Task Force, suggested that women make an individual choice on getting mammography from ages 40 to 49.

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MIT researchers find circadian rhythms in liver function influence drugs’ effectiveness

Pharma Times

An estimated 50% of human genes follow a circadian cycle, many of which are active in the liver

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Navigating Payroll Compliance: Future-Proofing Payroll in an Evolving Regulatory Landscape

Speaker: Jennifer Hill

Payroll compliance is a cornerstone of business success, yet for small and midsize businesses, it’s becoming increasingly challenging to navigate the ever-evolving landscape of federal, state, and local regulations. Mistakes can lead to costly penalties and operational disruptions, making it essential to adopt advanced solutions that ensure accuracy and efficiency.

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STAT+: In a big reversal, Walmart to shut down medical clinics and online care

STAT

Walmart had grand ambitions , back in 2019, to grow a network of cheaper primary care clinics attached to its ubiquitous stores. Those ambitions are now dead. The retail giant said Tuesday it is shuttering its 51 medical clinics across five states, as well as its virtual care offering. Walmart attributed the decision to low payments from health insurers and high costs to operate the clinics.

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STAT+: Eli Lilly raises earnings guidance as Zepbound sales beat expectations

STAT

Eli Lilly raised its full-year guidance on Tuesday while it reported strong first-quarter sales of Zepbound, even as the pharmaceutical company struggles to make enough of the obesity drug to meet the enormous demand. Lilly increased its adjusted earnings guidance for 2024 to a range of $13.50 to $14.00 per share, up from a prior forecast of $12.20 to $12.70 per share.

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Embracing new delivery models in the UK

pharmaphorum

Learn about the exciting developments in healthcare delivery in the UK, including the IDX2 trial, NHS initiatives, NIHR research, and the Digital Delivery Team. Explore how these new delivery models are revolutionising healthcare.

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Backers of menthol cigarette ban vow to keep up the fight, but concede it will be a long battle

STAT

WASHINGTON — Advocates of a federal ban on menthol cigarettes have spent the better part of the last decade trying everything — from federal lawsuits to holding mock funerals outside the White House — to convince Washington policymakers to remove the minty substance from cigarettes. Now, it seems, advocates may just have to sit around and wait.

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Walmart retreats from healthcare, closing clinics across US

pharmaphorum

For the last few years, Walmart has been promising to disrupt the US healthcare sector with a national network of clinics providing low-cost care and telehealth services. Now, it is reining back on those plans.

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From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

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DEA will move to reclassify marijuana in a historic shift, AP sources say

STAT

WASHINGTON — The U.S. Drug Enforcement Administration  will move to reclassify  marijuana  as a less dangerous drug, The Associated Press has learned, a historic shift to generations of American drug policy that could have wide ripple effects across the country. The DEA’s proposal, which still must be reviewed by the White House Office of Management and Budget, would recognize  the medical uses of cannabis  and acknowledge it has less potential for abuse th

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Enlaza gets JP Morgan, Regeneron backing for covalent biologics

BioPharma Dive

The funds will help the cancer-focused startup Enlaza bring “several development candidates” towards human testing in the next few years, its CEO said.

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Opinion: Protect the health of pregnant people and their children by including them in research

STAT

Imagine having to make this decision: Your health care provider recommends that you take a specific medicine for an illness or condition but then tells you it hasn’t been tested in people like you. Do you take the medication, or refuse it? That’s the position the 3.5 million women who give birth each year in the U.S. are in when being counseled about taking medicines.

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Lilly hikes revenue forecast by $2B as GLP-1 drug sales climb

BioPharma Dive

Supply continues to be tight, however, and the company anticipates further sales growth to be limited by how quickly it can bring on additional production capacity.

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Why Every Small Business Needs an HCM Solution: A Comprehensive Guide

Managing HR tasks like payroll, compliance, and employee data can overwhelm small businesses. That’s where a Human Capital Management (HCM) solution comes in. Our eBook, Why Every Small Business Needs an HCM Solution: A Comprehensive Guide , shows how an HCM system automates tedious processes, ensuring your business stays compliant and efficient. You’ll learn how to simplify payroll, eliminate costly errors, and empower your employees with self-service tools.

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Opinion: The medical loss ratio has become a barrier to preventive care

STAT

Health care regulations in the United States were not designed to keep Americans healthy. The best example of this is what’s known as the medical loss ratio (MLR). This federal requirement establishes how much a health plan can spend on non-medical related items. The goal was to ensure that insurance dollars are being spent on health care, not administrative costs.

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California to sell state-branded Narcan generic to cut costs

pharmaphorum

California will start selling its own generic of overdose reversal agent naloxone in another example of the use of government-level purchasing power to reduce drug prices

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FDA wants to hear your thoughts on advisory committees 

STAT

Want to stay on top of the science and politics driving biotech today?  Sign up  to get our biotech newsletter in your inbox. Hello, I’m up bright and early today to report on earnings, with the help of some coffee (with  pasteurized milk)  and the  soundtrack  for the new Challengers movie.

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Now a biopharma powerhouse, Vertex’s R&D bedrock could deliver tomorrow’s blockbusters

PharmaVoice

From its landmark CRISPR approval to its potential breakthrough drug for pain, Vertex’s development approach, led by chief scientific officer Dr. David Altshuler, is paying off.

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Best Practices to Streamline Compensation Management: A Foundation for Growth

Speaker: Joe Sharpe and James Carlson

Payroll optimization can be one of the most time-consuming and complex factors of small business management. Yet, organizations that crack the code on streamlining employee compensation often discover innovative avenues for growth. With the right strategies in place, outsourcing and streamlining payroll processes can result in substantial time and resource savings.

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STAT+: ‘Skinny labels’ on generic medicines saved Medicare $15 billion over a recent six-year period

STAT

A controversial provision of a federal law designed to speed copycat drugs to market and foster competition saved Medicare Part D nearly $15 billion from 2015 to 2021 on just 15 medicines during that period, according to a new analysis. The provision is known as skinny labeling, which refers to a move by a company that seeks regulatory approval to market a generic or biosimilar medicine for a specific use, but not for other patented uses for which the brand-name drug is prescribed.

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Tiffany Capps: A (CPESN) Beacon of Excellence

PioneerRx

“There's just so many things out there for pharmacies to maximize,” says Tiffany Capps, a pharmacy tech and CPESN’s Pharmacy Operations and Communications Lead.

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STAT+: Akili to lay off 46% of its staff, explore strategic options amid sluggish sales

STAT

Akili Interactive on Tuesday announced it will lay off 46% of its staff and evaluate strategic alternatives amid sluggish sales of its prescription video game treatment for attention deficit hyperactivity disorder. The announcement comes ahead of the company’s first-quarter earnings release on May 14. Akili’s hunt for options follows dismal outcomes for other prescription digital therapeutics companies that have thrown in the towel after failing to build sustainable businesses.

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Pharma Pulse 4/30/24: Advocating For Weight Loss Medication, AI Start-Ups Face Rough Financial Reality Check & more

Pharmaceutical Commerce

The latest news for pharma industry insiders.

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Enhance Healthcare Efficiency With Top Payroll & HCM Services

Running a healthcare facility requires precision and care, not just for patients but also for your staff. Our guide, "A Buyer’s Guide to Payroll & HCM Services," helps healthcare providers choose the best provider. Efficient payroll management ensures timely, accurate payments, critical for maintaining staff morale and trust. Compliance support helps navigate complex healthcare regulations and avoid costly fines.

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STAT+: Former MIT biologist David Sabatini, forced out after sexual harassment accusations, to lead new Boston team

STAT

Former MIT and Whitehead Institute star biologist David Sabatini, who lost his lofty positions after being accused of violating sexual harassment policies in 2021, is rejoining the Boston scientific community as head of a research group at a new laboratory under the umbrella of a Czech-based scientific institute. Sabatini, who has denied harassing anyone and filed litigation over the claims, has been working since last October in a senior research position at the Institute of Organic Chemistry a

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Merck KGaA Financially Commits $322 Million Toward Research Center

Pharmaceutical Commerce

The complex will research solutions for manufacturing antibodies, mRNA applications, and more.

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San Diego’s life sciences sector struggles for financial security

STAT

LA JOLLA, Calif. — About a half century ago, a barren ocean bluff here started sprouting research institutions, turning a backwater Navy town into a much-envied icon of high-tech jobs and biomedical discoveries. But after years of plunging federal grants and nagging national economic difficulties, the independent institutes on Torrey Pines Mesa are at a crossroads.

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Prime editing comes of age as FDA clears human trials

pharmaphorum

Prime Medicine has been given the go-ahead by the FDA for the first human trial of its prime editing technology, which promises to deliver one-shot therapies for a range of severe genetic diseases.

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Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.