Thu.Feb 20, 2025

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STAT+: How much weight loss is too much? Pharma is pushing the limit with new obesity drugs

STAT

In ongoing trials of Eli Lilly’s next-generation obesity drug, several trial participants are running into an issue they never expected: They are losing too much weight. One participant lost 22% of her weight in nine months — substantially faster than the rate seen with approved GLP-1 drugs like Wegovy or Zepbound. Her weight dropped so much that researchers reduced her dose of the treatment, called retatrutide.

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CDMO Live 2025 to spotlight the future of pharmaceutical outsourcing in Europe

Express Pharma

CDMO Live is set to take place on 7-8 May 2025 at Rotterdam’s World Trade Center, bringing together key decision-makers in pharmaceutical outsourcing. As the sector continues its rapid expansion, with a 7 per cent annual growth rate, the event will highlight the increasing reliance on contract development and manufacturing organisations (CDMOs) in bringing new therapies to market.

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Trending Sources

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Opinion: HHS’ national health security division must be preserved

STAT

Change has come to the Department of Health and Human Services. With the confirmation of Robert F. Kennedy Jr. as secretary, major shifts in organizational structure, staffing , and policy priorities across the department are already underway. But not all HHS agencies are created equal, and some deserve to be modified with a scalpel rather than a sledgehammer.

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How to Achieve High-Quality Standards in Generic Drugs

Drug Patent Watch

The Unseen Heroes of the Pharmaceutical Industry: Achieving High-Quality Standards in Generic Drugs As we navigate the complex world of healthcare, it's easy to overlook the unsung heroes who work tirelessly behind the scenes to bring affordable, high-quality medications to the masses. I'm talking about the generic drug manufacturers who play a vital role in making life-saving treatments accessible to people worldwide.

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Navigating Payroll Compliance: Future-Proofing Payroll in an Evolving Regulatory Landscape

Speaker: Jennifer Hill

Payroll compliance is a cornerstone of business success, yet for small and midsize businesses, it’s becoming increasingly challenging to navigate the ever-evolving landscape of federal, state, and local regulations. Mistakes can lead to costly penalties and operational disruptions, making it essential to adopt advanced solutions that ensure accuracy and efficiency.

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Opinion: The health policy cult’s misplaced faith in government

STAT

Mainstream policy analysts are convinced that government, and only government, can save us from the monster the U.S. health care system has become.  That’s why their recommended solutions to the system’s many problems all have government at their core.

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STAT+: Why biotech’s future is threatened by zombies

STAT

This story first appeared in Adam’s Biotech Scorecard, a subscriber-only newsletter. STAT+ subscribers can sign up  here  to get it delivered to their inbox. I was a bit worried last week’s angst-y rant on the bleak state of biotech investing would turn folks off. In fact, it was my most popular newsletter ever, with the version posted to STAT’s website delivering a ton of new subscribers.

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IGBA releases first global Intellectual Property and Competition Report

Express Pharma

The International Generic and Biosimilar Medicines Association (IGBA) has released a report titled “Gaming the System An Overview of Originator Companies Evergreening Strategies Used to Hinder Access to Generic and Biosimilar Products.” The report outlines market practices that delay the entry of generic and biosimilar medicines, affecting affordability and competition in global healthcare.

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A newly developed machine learning-based test could diagnose autoimmune diseases faster

STAT

Every time you get sick, your body keeps a record of it.

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FDA approves Deciphera’s Romvimza for rare tumour type

Pharma Times

Tenosynovial giant cell tumours can cause pain, stiffness, swelling and movement limitations

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From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

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The U.S. could face a national hospital bed shortage

STAT

Get your daily dose of health and medicine every weekday with STAT’s free newsletter Morning Rounds.  Sign up here. Good morning! Got a meaty newsletter for you today, so let’s dive in.

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Pharmacists’ Role in Optimizing Outcomes for Women With Complex Health Needs

Pharmacy Times

Panelists discuss how pharmacists play a crucial role in optimizing health outcomes for women with complex health needs through comprehensive medication management, personalized consultations, and interdisciplinary collaboration. They provide targeted medication therapy, monitor drug interactions, offer medication counseling, manage chronic conditions, support reproductive health, and help patients navigate complex treatment regimens with expertise and compassionate care.

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Risky weight loss, grad school acceptance cuts, and more major biotech news of the day

STAT

Want to stay on top of the science and politics driving biotech today?  Sign up  to get our biotech newsletter in your inbox. Good morning, let’s get straight into the news today — including one story I’ve been spending some time on.

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Lilly’s former M&A chief scours the landscape for potential deals as Immunocore’s new CFO

PharmaVoice

Travis Coy is using his Big Pharma bona fides to prioritize business development at the diversified and growing company.

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Why Every Small Business Needs an HCM Solution: A Comprehensive Guide

Managing HR tasks like payroll, compliance, and employee data can overwhelm small businesses. That’s where a Human Capital Management (HCM) solution comes in. Our eBook, Why Every Small Business Needs an HCM Solution: A Comprehensive Guide , shows how an HCM system automates tedious processes, ensuring your business stays compliant and efficient. You’ll learn how to simplify payroll, eliminate costly errors, and empower your employees with self-service tools.

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FDA cuts, zombie biotechs, and too much weight loss?

STAT

How will cuts to Food and Drug Administration staff affect the drug industry? Are companies pushing for too much weight loss from new drugs? And what will bring biotech out of its doldrums? We discuss all that and more on the latest episode of “The Readout LOUD.” Mizuho analyst Jared Holz joins to discuss Adam’s column on biotech’s dark period.

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AstraZeneca deepens China presence with FibroGen deal

BioPharma Dive

The $160 million acquisition of a FibroGen subsidiary expands AstraZeneca’s foothold in China while the company works through government investigations into its business practices there.

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Pharma and medtech industry reacts to FDA, CDC and NIH job cuts

Pharmaceutical Technology

The FDA, NIH and CDC has cut 5,200 probationary staff in a job cull across the HHS over the Valentine's Day weekend.

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In FDA job cuts, experts see threat of far-reaching impact

BioPharma Dive

"Any place that gets cut, it's going to have an impact, because there's not any spare personnel at FDA,” said former agency commissioner Robert Califf.

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Best Practices to Streamline Compensation Management: A Foundation for Growth

Speaker: Joe Sharpe and James Carlson

Payroll optimization can be one of the most time-consuming and complex factors of small business management. Yet, organizations that crack the code on streamlining employee compensation often discover innovative avenues for growth. With the right strategies in place, outsourcing and streamlining payroll processes can result in substantial time and resource savings.

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SMA treatment with Evrysdi 'could start prenatally'

pharmaphorum

SMA treatment with Evrysdi 'could start prenatally' Phil.

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CDC vaccine meeting, set to be first since RFK Jr. sworn in, is postponed

BioPharma Dive

Originally scheduled for next week, the meeting of agency advisers will be delayed to give more time for public comment, according to an HHS spokesperson.

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Boehringer eyes third quarter FDA verdict for oral HER2 drug

pharmaphorum

Boehringer Ingelheim's oral HER2 inhibitor zongertinib has started an FDA review as a lung cancer treatment with a decision due in the third quarter.

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Daily drug captures health benefits of high-altitude, low-oxygen living

World Pharma News

For the average person, living at high altitude - where oxygen is sparser than at sea level - can have health benefits ranging from lower rates of heart disease to increased endurance. But for those born with inherited mitochondrial diseases, who rarely survive past childhood, low-oxygen air like that found at mountain peaks could be life-saving, potentially extending their lifespan and eliminating their symptoms.

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Enhance Healthcare Efficiency With Top Payroll & HCM Services

Running a healthcare facility requires precision and care, not just for patients but also for your staff. Our guide, "A Buyer’s Guide to Payroll & HCM Services," helps healthcare providers choose the best provider. Efficient payroll management ensures timely, accurate payments, critical for maintaining staff morale and trust. Compliance support helps navigate complex healthcare regulations and avoid costly fines.

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UCB's non-cannabis drug for severe epilepsy gets NHS okay

pharmaphorum

Around 1,400 patients with Lennox-Gastaut Syndrome will be eligible for NHS treatment with UCB's Fintepla after a NICE recommendation

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Google Launches AI Co-Scientist System

PharmaTech

The AI co-scientist is a multi-agent AI system that can work as a virtual scientific collaborator.

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BridgeBio’s heart drug launch gets off to a fast start

BioPharma Dive

Prescription totals for Attruby, which is locked in a closely watched commercial battle with Pfizer’s tafamidis, have more than doubled since January and outpaced investor expectations.

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Ask the Expert: Complying with 21 CFR 211.110

PharmaTech

In this episode of the Ask the Expert video series, Susan J. Schniepp, distinguished fellow at Regulatory Compliance Associates, and Siegfried Schmitt, PhD, vice president, Technical at Parexel, discuss the implications of FDAs new draft guidance on complying with 21 CFR 211.110.

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Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.