Fri.Aug 16, 2024

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As climate changes, scorching summers bring deadly heat for people with disabilities

STAT

Degree by degree, the earth’s temperature ticks up. Heat records fall as reliably as the sun sets. In July, the East Coast broiled. This week, Texas and its neighbors are feeling the burn. It’s been an absolute scorcher in the United States, the hottest summer on record. This summer might also be one of the coolest summers for the rest of your life.

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The drugs hit hardest by Medicare price negotiations

PharmaVoice

The final negotiations slash drug prices between 38% and 79% for Medicare’s 2026 calendar year.

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STAT+: Pfizer and BioNTech effort to develop Covid-influenza combination vaccine sees setback

STAT

Pfizer and BioNTech said Friday that their combined mRNA vaccine candidate against influenza and Covid-19 showed a lower immune response against one type of influenza, influenza B, in a Phase 3 trial, a setback for the vaccine. The combination vaccine met its goal in generating an immune response against influenza A and against the SARS-CoV-2 virus, which causes Covid, the companies said in a statement.

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Not if, but when: Pandemic preparedness is crucial

pharmaphorum

On Wednesday, 14th August, the World Health Organization (WHO) announced the mpox outbreak in Africa as a public health emergency of international concern (PHEIC). By Thursday, 15th August, the first case of the severe variant was reported in Sweden, marking its emergence outside of Africa.

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From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

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More than 70 babies have been born from uterus transplants: ‘It’s a complete new world’

STAT

The first modern attempt at transferring a uterus from one human to another occurred at the turn of the millennium. But surgeons had to remove the organ, which had become necrotic, 99 days later. The first successful transplant was performed in 2011 — but even then, the recipient wasn’t immediately able to get pregnant and deliver a baby.

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Pfizer, BioNTech stumble in effort to develop combination flu, COVID shot

BioPharma Dive

The vaccine didn’t spur a strong enough immune response against a particular flu strain in a Phase 3 trial, leading the companies to ponder adjustments.

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October vaccination start could stretch pharmacy capacity, IPA warns

The Pharmacist

The October start date for Covid and flu vaccinations will cause 'problems with capacity' for community pharmacies as they juggle increased prescriptions and seasonal ailments alongside the vaccination programme, the chief executive of the Independent Pharmacies Association (IPA) has warned. This comes as NHS England (NHSE) confirmed this week that the main flu and Covid […] The post October vaccination start could stretch pharmacy capacity, IPA warns appeared first on The Pharmacist.

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The story of the giraffe, its neck, and a possible treatment for human heart disease

STAT

For much of Barbara Natterson-Horowitz’s career, her work has revolved around one idea: The field of human medicine has suffered from being too human-centered. Natterson-Horowitz is a cardiologist, psychiatrist, and evolutionary biologist who co-authored the 2012 book “ Zoobiquity: The Astonishing Connection Between Human and Animal Health.

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Keeping Counterfeit Goods Out of the Supply Chain

Pharmaceutical Commerce

In the final part of his Pharma Commerce video interview, Michael Rowe, Two Labs’ Senior Director of DSCSA/Serialization Compliance Services, comments on other ways to limit ‘bad actors’ attempts to sneak counterfeit drugs into the supply chain, aside from the DSCSA.

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Opinion: Gilead must be held accountable for the harm caused by ‘patent hopping’ an HIV treatment

STAT

Gilead Sciences, a pharma company that dominates the market for HIV treatments, agreed in June to settle a case in federal court for $40 million that had been brought by 2,625 people living with HIV. But as a similar and far larger case looms in California courts, right-leaning, big-business-can-do-no-wrong opinion columnists and editorial boards are claiming the lawsuit threatens to destroy the pharmaceutical industry’s ability to innovate.

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Why Every Small Business Needs an HCM Solution: A Comprehensive Guide

Managing HR tasks like payroll, compliance, and employee data can overwhelm small businesses. That’s where a Human Capital Management (HCM) solution comes in. Our eBook, Why Every Small Business Needs an HCM Solution: A Comprehensive Guide , shows how an HCM system automates tedious processes, ensuring your business stays compliant and efficient. You’ll learn how to simplify payroll, eliminate costly errors, and empower your employees with self-service tools.

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FOPE and Pharma State Academy focus on Quality Risk Management in latest PULSE session

Express Pharma

FOPE and Pharma State Academy recently hosted, third session of their PULSE series on August 11, 2024, spotlighting “Quality Risk Management (QRM)” with a special focus on the Revised Schedule M. The session drew significant participation from across the pharmaceutical industry, underscoring the critical importance of risk management in ensuring product safety and regulatory compliance.

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The story of the giraffe, its neck, and a possible treatment for human heart disease

STAT

For much of Barbara Natterson-Horowitz’s career, her work has revolved around one idea: The field of human medicine has suffered from being too human-centered. Natterson-Horowitz is a cardiologist, psychiatrist, and evolutionary biologist who co-authored the 2012 book “ Zoobiquity: The Astonishing Connection Between Human and Animal Health.

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Medicare Unveils Results of First-Round Drug Price Negotiations

Pharmaceutical Commerce

By 2026, the first 10 drugs for individuals with Part D coverage—whose medications are mainly used to treat cancer, diabetes, and heart disease—will see discounts off of list prices ranging from 38-79%.

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Opinion: STAT+: What the newly released Medicare prices for 10 drugs do and don’t tell us

STAT

For many of us, Thursday was Health-Policy-Wonk Festivus.  The Centers for Medicare & Medicaid Services released the Maximum Fair Prices (MFPs) for the first 10 drugs subject to negotiation under the Inflation Reduction Act. This is an important moment in prescription drug pricing policy. For the first time, CMS had the opportunity to analyze current clinical evidence, unmet needs, and other related considerations as they negotiated the prices of these 10 drugs.

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Best Practices to Streamline Compensation Management: A Foundation for Growth

Speaker: Joe Sharpe and James Carlson

Payroll optimization can be one of the most time-consuming and complex factors of small business management. Yet, organizations that crack the code on streamlining employee compensation often discover innovative avenues for growth. With the right strategies in place, outsourcing and streamlining payroll processes can result in substantial time and resource savings.

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With FDA okay, AZ takes on MSD in early-stage lung cancer

pharmaphorum

AstraZeneca has claimed FDA approval for its immunotherapy Imfinzi before and after surgery for non-small cell lung cancer, setting up a contest with MSD's rival Keytruda.PD-L1 inhibitor Imfinzi (durvalumab) has been cleared for use in adult patients who need surgery for early-stage (IIA-IIIB) NSCLC and have no ALK or EGFR mutations that would make them suitable for targeted therapies.

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STAT+: Up and down the ladder: The latest comings and goings

STAT

Hired someone new and exciting? Promoted a rising star? Finally solved that hard-to-fill spot? Share the news with us, and we’ll share it with others.  That’s right. Send us your changes, and we’ll find a home for them. Don’t be shy. Everyone wants to know who is coming and going. And here is our regular feature in which we highlight a different person each week.

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Public health warning over rising rates of antibiotic-resistant gonorrhoea

The Pharmacist

Public health officials are warning of a concerning rise in antibiotic-resistant gonorrhoea infections in England. Data from the UK Health Security Agency shows there have been 15 new confirmed cases of ceftriaxone-resistant Neisseria gonorrhoeae between June 2022 and May 2024. This includes five cases which were extensively drug-resistant to first and second line antibiotics as well […] The post Public health warning over rising rates of antibiotic-resistant gonorrhoea appeared first on T

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STAT+: Pharmalittle: We’re reading about a Covid-flu shot setback, mpox vaccine supplies, and more

STAT

And so, another working week will soon draw to a close. Not a moment too soon, yes? This is, you may recall, our treasured signal to daydream about weekend plans. Our agenda is fairly modest. We hope to hang with a couple of our short people, spend time with our Pharmalot ancestor, and promenade with the official mascots. We also hope to hold another listening party, where the rotation will likely feature this , this , this , this and this.

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Enhance Healthcare Efficiency With Top Payroll & HCM Services

Running a healthcare facility requires precision and care, not just for patients but also for your staff. Our guide, "A Buyer’s Guide to Payroll & HCM Services," helps healthcare providers choose the best provider. Efficient payroll management ensures timely, accurate payments, critical for maintaining staff morale and trust. Compliance support helps navigate complex healthcare regulations and avoid costly fines.

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AstraZeneca wins approval for Imfinzi in NSCLC perioperative setting

Pharmaceutical Technology

The FDA approval of Imfinzi in this indication comes a month after the agency called for an overhaul of perioperative lung cancer trials.

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‘Zoobiquity’: How animals have figured out disease better than humans

STAT

Want to stay on top of health news?  Sign up  to get our Morning Rounds newsletter in your inbox. On Thursday was my two-year STAT-iversary. I can’t believe I’ve been here for that long!

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Pharmacy numbers set to reach lowest level in 20 years, NPA warns

The Pharmacist

The number of community pharmacies is set to reach its lowest level in 20 years by the end of next month, the National Pharmacy Association (NPA) has warned. With an average of seven pharmacies closing a week so far this year, the NPA said that by the end of September, the current 10,054 could dip […] The post Pharmacy numbers set to reach lowest level in 20 years, NPA warns appeared first on The Pharmacist.

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Is pharma still fearful of the Inflation Reduction Act?

STAT

Want to stay on top of the science and politics driving biotech today?  Sign up  to get our biotech newsletter in your inbox. Good summer morning! Today, we discuss the big Medicare price negotiations (and the not-entirely-meaningful numbers the White House is touting), see a 75% personnel cut at Lykos Therapeutics, and more.

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Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

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Top 20 global biopharma companies report 4.3% growth in market capitalisation in Q2 2024, reveals GlobalData

Express Pharma

The biopharmaceutical industry remained resilient in the second quarter (Q2) of 2024 as global markets and investor optimism improved with anticipation of a potential interest rate cut from the US Federal Reserve. The top 20 global biopharmaceutical companies reported a total increase of 4.3 per cent in market capitalisation from $3.8 trillion as on 31 March 2024 to $4 trillion as on 30 June 2024, reveals GlobalData.

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Pfizer and BioNTech’s Covid-19/flu combination vaccine falters in Phase III readout

Pharmaceutical Technology

While the vaccine demonstrated high responses for neutralizing influenza A titers, it failed to show sufficient efficacy against influenza B.

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Researchers map interactions of 144 active substances to identify drug benefits

Pharma Times

The study yielded over one million dose-responsive curves for existing cancer drugs

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As WHO calls mpox emergency, NIH says only drug ineffective

pharmaphorum

As WHO declares mpox an emergency, the only recognised drug treatment for the virus, Siga's tecovirimat, fails a clinical trial.

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5 Reasons to Upgrade Your Pharmacy Management Software

Are you still using workarounds to manage your daily operations? To achieve peak performance, it's time to explore other options for specialty and infusion pharmacy software. Streamline pharmacy operations and improve clinical performance with automated processing, real-time data exchange, and electronic decision support. Download this helpful infographic to: Drive efficiency and patient adherence from referral receipt to delivery and ongoing care – all with our Pharmacy Cloud.

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The Genomic Medicine Revolution: Multi-Modality Approaches in Advanced Therapies 

Pharmaceutical Technology

Genomic medicines offer new techniques for treating conditions once thought to be intractable - a world of opportunity awaits.

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Overcoming regulatory hurdles to unleash breakthrough innovations: Cell and gene therapies and radiopharmaceuticals

pharmaphorum

Overcoming regulatory hurdles to unleash breakthrough innovations: Cell and gene therapies and radiopharmaceuticals Mike.

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Wanbury appoints Prakash Venkatraman as President of API business

Express Pharma

Wanbury has appointed Prakash Venkatraman as the President of its API business, bringing over three decades of experience in API operations, business strategy, and P&L management to the role. Prakash Venkatraman holds a Bachelor’s degree in Chemical Engineering and a Master’s degree in Management Studies from Mumbai University. His career includes key leadership roles in several prominent pharmaceutical companies.

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Lykos co-founder Doblin to step down after MDMA setback

pharmaphorum

Lykos Therapeutics is slashing staff after the FDA turned down its MDMA-assisted therapy for PTSD, while founder Rick Doblin is stepping down.

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Medicare drug price cuts could have limited early impact, but grow with time

BioPharma Dive

Some industry watchers described the level of price discounts announced by Medicare as a "relief," though they warned of bigger future implications for drug research.