Wed.Oct 16, 2024

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Is it time to freak out about bird flu?

STAT

If you’re aware of the H5N1 bird flu outbreak in U.S. dairy cattle — you may have seen some headlines or read something on social media — perhaps you are wondering what the fuss is about. Yes, there have been nearly a couple dozen human cases, but all have had mild symptoms. The virus does not decimate herds in the way it does poultry flocks; most — though not all — of the infected cows come through the illness OK.

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Want to launch a blockbuster? An AstraZeneca exec breaks it down.

PharmaVoice

Even drugs with “blockbuster potential” often fall short of expectations. Here’s what can help a new medication pass the $1 billion mark.

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Trending Sources

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STAT+: Inside UnitedHealth’s strategy to pressure physicians: $10,000 bonuses and a doctor leaderboard

STAT

The emails from UnitedHealth Group managers were filled with exclamation marks and pleasantries about the weather. But the underlying message to doctors in late 2020 was persistent and urgent: Hit your targets to see more patients. We need to bring in more money. At the time, deaths from Covid-19 were surging, and no vaccine was available.

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Rising Pharmaceutical Costs: A Major Challenge for Managed Healthcare

Drug Patent Watch

One issue continues to loom large in healthcare: the skyrocketing costs of pharmaceuticals. This challenge has become a significant hurdle for managed healthcare organizations, patients, and policymakers alike.

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Navigating Payroll Compliance: Future-Proofing Payroll in an Evolving Regulatory Landscape

Speaker: Jennifer Hill

Payroll compliance is a cornerstone of business success, yet for small and midsize businesses, it’s becoming increasingly challenging to navigate the ever-evolving landscape of federal, state, and local regulations. Mistakes can lead to costly penalties and operational disruptions, making it essential to adopt advanced solutions that ensure accuracy and efficiency.

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Veteran vaccine developer says U.S. response to bird flu outbreak in cattle is ‘frustrating’

STAT

Barney Graham, who for decades helped lead U.S. vaccine development efforts , said Wednesday that the lack of cooperation among U.S. agencies is hindering the country’s response to the H5N1 bird flu outbreak among dairy cattle, echoing criticisms that have been building over the past six months.  “The USDA and the CDC and the NIH are not sharing and coordinating,” Graham said, referring to the federal agriculture department, the Centers for Disease Control and Preventio

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‘Failure to rescue’: Study suggests why women fare worse than men after cardiovascular surgery

STAT

They call it “failure to rescue,” which means a surgical patient died from complications that might have been averted if recognized and treated. New research suggests that’s why women are less likely to survive high-risk cardiovascular surgery than men. Female patients who underwent four common but serious procedures —  abdominal aortic aneurysm repair, coronary artery bypass surgery, or atrial or mitral valve replacements — later developed complications a

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Wave sees RNA editing validation in early trial results

BioPharma Dive

The results provide the first clinical evidence of RNA editing, a burgeoning field that's drawn interest from biotechs and pharmaceutical companies alike.

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Their research may be transformative. They worry patients won’t be able to access it

STAT

Inspiration for a career in science can come from any number of sources. For Diane Shao , a neurogeneticist at Boston Children’s Hospital and general partner at Legacy Venture Capital, her mother motivated her to take the plunge into biotech. For Jorge Diego Martin-Rufino , a physician scientist at the Broad Institute and Boston Children’s Hospital, it was the pioneering geneticist Eric Lander, who advised him during his Ph.D.

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Weight-loss drug firm accused of prioritising profits after halting insulin pen production

The Guardian - Pharmaceutical Industry

Novo Nordisk’s decision will force people in developing countries to use outdated glass vials and syringes, warn campaigners The pharmaceutical company behind injectable weight-loss drugs has been accused of prioritising profits over the health of people in developing countries by halting production of its insulin pens. People living with type 1 diabetes who are reliant on the human insulin produced by Novo Nordisk, will instead be given glass vials and syringes – which they say are inconvenient

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From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

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Opinion: Mark Cuban has no doubt he can disrupt health care

STAT

If it weren’t for Martin Shkreli, better known as the Pharma Bro, Mark Cuban might not have gone into the drug business. That’s what he told me in this week’s episode of the “First Opinion Podcast.” He first started speaking with Alex Oshmyansky — the radiologist who would become his co-founder in Mark Cuban Cost Plus Drugs — around when Shkreli was heading to prison.

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Pfizer sticks $1.5bn on Triana's molecular glue tech

pharmaphorum

Pfizer partners with US biotech Triana Biomedicines in a deal focusing on molecular glue degraders that could be worth $1.

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STAT+: Q&A: FDA chief on why our hearts are less healthy, how obesity drugs impress him, and what worries him

STAT

Robert Califf, a cardiologist and commissioner of the U.S. Food and Drug Administration, has been deeply involved in cardiovascular research: investigating health outcomes, health care quality, and clinical research in large, complex studies. In a recent conversation with STAT, though, he invoked his role as a grandfather, challenged in a grocery store checkout line to resist the ultra-processed foods marketed to American children and adults.

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NIH study backs Bavarian Nordic mpox jab for adolescents

pharmaphorum

NIH study finds Bavarian Nordic's mpox vaccine is effective in adolescents, a particularly vulnerable group amid the ongoing outbreak

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Why Every Small Business Needs an HCM Solution: A Comprehensive Guide

Managing HR tasks like payroll, compliance, and employee data can overwhelm small businesses. That’s where a Human Capital Management (HCM) solution comes in. Our eBook, Why Every Small Business Needs an HCM Solution: A Comprehensive Guide , shows how an HCM system automates tedious processes, ensuring your business stays compliant and efficient. You’ll learn how to simplify payroll, eliminate costly errors, and empower your employees with self-service tools.

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Buoyed by clinical success, Onward Medical charts future of neurostimulation

STAT

Onward Medical is betting big on neurostimulation as a tool to improve the quality of life for people with paralysis, said CEO Dave Marver. Bullish after recent clinical success, Marver spoke about the Swiss company’s future plans at the 2024 STAT Summit in Boston, including a device that can better regulate an underactive bladder.

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Contractors and practices urged to adopt NHSE sexual misconduct framework

The Pharmacist

NHS England (NHSE) has launched a package of support to help staff report sexual misconduct at work, including an anonymous form. And it urged contractors to adopt and adapt its policy framework, as legal changes come into force this month requiring employers to take ‘reasonable steps’ to prevent sexual harassment. But NHSE confirmed to The Pharmacist that […] The post Contractors and practices urged to adopt NHSE sexual misconduct framework appeared first on The Pharmacist.

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STAT+: Ahead of public meeting, FDA signals flexibility in evaluating smoking cessation treatments

STAT

Food and Drug Administration leaders are signaling new flexibility in the agency’s approach to evaluating new therapies to help people stop smoking.  In a perspective paper published with the National Institutes of Health this week, the agency labeled the effort to help Americans quit smoking a top priority and said it was willing to consider broader endpoints in clinical trials of smoking cessation products.

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Analyzing the impact of biosimilars on biologic drug development pipelines

Drug Patent Watch

Biosimilars, which are biologic drugs that are highly similar to an already approved biologic drug, are transforming the pharmaceutical industry. As patents for original biologic drugs expire, biosimilars are becoming increasingly important, offering more affordable treatment options for patients and healthcare systems.

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Best Practices to Streamline Compensation Management: A Foundation for Growth

Speaker: Joe Sharpe and James Carlson

Payroll optimization can be one of the most time-consuming and complex factors of small business management. Yet, organizations that crack the code on streamlining employee compensation often discover innovative avenues for growth. With the right strategies in place, outsourcing and streamlining payroll processes can result in substantial time and resource savings.

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Morning Rounds: How UnitedHealth pressured doctors on diagnoses

STAT

Get your daily dose of health and medicine every weekday with STAT’s free newsletter Morning Rounds.  Sign up here. Good morning! My editor said that the uncertainty in my write-up below on Helen’s story (“ Is it time to freak out about bird flu? “) reminded her of this iconic moment from NBC’s “30 Rock.

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Access to genomic surveillance: Open science and public health

pharmaphorum

The pandemic served as a catalyst for a revolution in genomic surveillance for tracking pathogens. The technology proved vital in aiding understanding of the evolution of and spread of virus in real time to inform public health measures, ultimately accelerating drug and vaccine development.

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STAT+: Pharmalittle: We’re reading about using Lilly obesity drug to reduce sick days, Sanofi workers striking, and more

STAT

Hello, everyone, and how are you today? We are doing just fine, thank you, especially since the middle of the week is upon us. After all, we have made it this far, so we are determined to hang on for another couple of days. And why not? The alternatives — at least those we can identify — are not so appetizing. And what better way to make the time fly than to keep busy.

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GPhC: 'Managers must listen when pharmacists speak up'

The Pharmacist

Managers and leaders must listen to and learn from concerns raised by pharmacists, the chief executive of the General Pharmaceutical Council (GPhC) has said. In a video message for Speak Up Month, organised by the National Guardian's Office, Duncan Rudkin said he had been 'quite rightly' told by unions that 'it's all very well to […] The post GPhC: 'Managers must listen when pharmacists speak up' appeared first on The Pharmacist.

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Enhance Healthcare Efficiency With Top Payroll & HCM Services

Running a healthcare facility requires precision and care, not just for patients but also for your staff. Our guide, "A Buyer’s Guide to Payroll & HCM Services," helps healthcare providers choose the best provider. Efficient payroll management ensures timely, accurate payments, critical for maintaining staff morale and trust. Compliance support helps navigate complex healthcare regulations and avoid costly fines.

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A controversial approval for Novocure’s device

STAT

This story first appeared in The Readout newsletter.  Sign up for The Readout  and receive STAT’s award-winning biotech news delivered straight to your inbox.  Good morning. I’ve arrived in Boston for our annual STAT summit , and I successfully guilted my colleague Adam Feuerstein into baking me a cheesecake.

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FDA puts Novavax flu vaccine trials on hold

BioPharma Dive

The hold, which was made in response to a serious adverse event report, could impact the company’s plans to start a Phase 3 trial of a combination shot for COVID-19 and influenza.

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COPD market to reach $30.8 billion in 7MM by 2033: GlobalData

Express Pharma

The chronic obstructive pulmonary disease (COPD) market in the seven major markets (7MM*) is set to grow from $11.5 billion in 2023 to $30.8 billion in 2033, driven by the launch of the first biologic for COPD, and other pioneering pipeline agents, forecasts GlobalData. GlobalData’s latest report, “COPD in Major Markets, Disease Management, Epidemiology, Pipeline Assessment, Unmet Needs and Drug Forecast to 2033,” reveals that the growth will be supported by approval from the FDA and EMA for Sa

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GSK claims Moderna infringed mRNA vaccine patents

BioPharma Dive

The pharma’s lawsuit focuses on scientific work that helped clear the path for creating mRNA vaccines to fight the COVID-19 pandemic.

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Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.