Thu.Aug 08, 2024

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As Covid deaths drop, heart disease and cancer remain leading causes of death

STAT

Since its emergence in 2020, Covid has jumbled the list of the 10 leading causes of deaths in the United States. It roared into third place in 2020 but has now fallen to 10th place, the National Center for Health Statistics reported Thursday.  Heart disease and cancer remained the first and second leading causes of death, followed by unintentional injuries as No. 3.

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Market share shakeup: Big Pharma’s bestselling drugs drive industry shifts in 2024’s first half

PharmaVoice

The top drugs at each of the world’s most valuable pharma companies tell the story of just how much the industry has changed over the course of a few years.

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Scientists are starting to uncover how neighborhood can affect the biology of cancer

STAT

Where you live has a relationship to your odds of getting cancer and surviving cancer. Epidemiologists studying this link they see in the data have focused on so-called social determinants of health — poor access to transportation, for example, could make it harder for residents to see a doctor. Places lacking grocery stores with fresh food could mean worse nutrition for locals.

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Roche licenses Sangamo’s technology for another shot at Alzheimer’s drugs

PharmaVoice

Through a new deal, Roche has exclusive rights to Sangamo molecules designed to repress the gene that makes “tau,” a protein many scientists view as a main driver of Alzheimer’s.

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Why Every Small Business Needs an HCM Solution: A Comprehensive Guide

Managing HR tasks like payroll, compliance, and employee data can overwhelm small businesses. That’s where a Human Capital Management (HCM) solution comes in. Our eBook, Why Every Small Business Needs an HCM Solution: A Comprehensive Guide , shows how an HCM system automates tedious processes, ensuring your business stays compliant and efficient. You’ll learn how to simplify payroll, eliminate costly errors, and empower your employees with self-service tools.

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STAT+: AI drug developers Recursion, Exscientia to merge

STAT

Two of the leading companies in the AI drug development field, Recursion Pharmaceuticals and Exscientia, said Thursday that they will merge into one company. The new company will continue using the Recursion name and be led by Recursion co-founder and CEO Chris Gibson. Exscientia’s interim CEO, David Hallett, will serve as the company’s science chief.

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Lilly boosts outlook on rising Zepbound revenue

BioPharma Dive

Sales of the in-demand obesity drug crested $1 billion in the second quarter as improved Lilly production helped the company fulfill wholesaler backorders.

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Study reveals AI insights can predict development of disease a decade in advance

Pharma Times

The study predicted the development of conditions including Alzheimer’s and heart disease

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How experiencing famine in the womb may shape people’s health as adults

STAT

Hunger killed an estimated 4 million people in Ukraine between 1932 and 1933 — the result of Holodomor, a famine inflicted by the Stalin-led Soviet regime. New research shows how the harm experienced during famines can extend even to people who haven’t yet been born. The study , published Thursday in Science, strengthens the link between fetal exposure to famine and increased risk for type 2 diabetes later on in life.

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Zepbound shortages ease, but Lilly cautions pharmacy availability may remain ‘choppy’

BioPharma Dive

After months of supply strains, Lilly has begun to catch up with demand. Consumers may still need to wait for their prescriptions to be filled, however.

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STAT+: Eli Lilly boosts 2024 revenue guidance by $3 billion on Mounjaro, Zepbound sales

STAT

Eli Lilly raised its full-year revenue guidance by $3 billion, driven by massive sales of its GLP-1-based diabetes and obesity drugs Mounjaro and Zepbound. The pharma giant on Thursday boosted its forecast for 2024 sales to a range of $45.4 billion to $46.6 billion from the previously guided range of $42.4 to $43.6 billion. It also raised its guidance for adjusted earnings per share to a range of $16.10 to $16.60 from the previously guided $13.50 to $14.00.

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Best Practices to Streamline Compensation Management: A Foundation for Growth

Speaker: Joe Sharpe and James Carlson

Payroll optimization can be one of the most time-consuming and complex factors of small business management. Yet, organizations that crack the code on streamlining employee compensation often discover innovative avenues for growth. With the right strategies in place, outsourcing and streamlining payroll processes can result in substantial time and resource savings.

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Merck discontinues Phase 3 trial for lung cancer combo drug

Express Pharma

Merck announced the discontinuation of the Phase 3 KeyVibe-008 trial based on the recommendation of an independent Data Monitoring Committee (DMC). The trial is evaluating the investigational fixed-dose combination (coformulation) of vibostolimab, an anti-TIGIT antibody, and pembrolizumab (KEYTRUDA), Merck’s anti-PD-1 therapy, in combination with chemotherapy compared to atezolizumab in combination with chemotherapy, for the first-line treatment of patients with extensive-stage small cell lung c

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STAT+: Big Health gets FDA nod for its digital therapy for insomnia

STAT

Digital Therapeutics developer Big Health this week received Food and Drug Administration clearance for SleepioRx, a prescription treatment for insomnia. Big Health already sells a wellness version of the app, called Sleepio, to employers and health plans that make the product available to their members. The app delivers a specialized type of cognitive behavioral therapy for insomnia and the company boasts that it is backed by dozens of studies.

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A Breadcrumb of Serialized Data

Pharmaceutical Commerce

In this part of his Pharma Commerce video interview, Michael Rowe, Two Labs’ Senior Director of DSCSA/Serialization Compliance Services, discusses the state of affairs surrounding the Drug Supply Chain Security Act, along with opportunities for improvement.

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Watch: How drug patents pave the way to profit

STAT

This is Part 3 of “Behind the Counter,” an in-depth video series demystifying the complex world of patents and drug pricing. Discovering a new drug is a big win for a pharmaceutical company, but selling it for lots of money with no competition? The cherry on top. This kind of market exclusivity is only possible because of patents.

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Enhance Healthcare Efficiency With Top Payroll & HCM Services

Running a healthcare facility requires precision and care, not just for patients but also for your staff. Our guide, "A Buyer’s Guide to Payroll & HCM Services," helps healthcare providers choose the best provider. Efficient payroll management ensures timely, accurate payments, critical for maintaining staff morale and trust. Compliance support helps navigate complex healthcare regulations and avoid costly fines.

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DCGI waives off local trials for drugs approved in well-regulated markets

Express Pharma

The CDSCO, with approval from the Central government, has notified a list of countries under rule 101 of the New Drugs and Clinical Trial Rules, 2019 that would, subject to conditions, consider the waiver of local clinical trials for several drugs if already approved in well-regulated markets. The countries on the list include the US, UK, Japan, Australia, Canada and the European Union.

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STAT+: Orlando Health, a $6 billion Florida powerhouse, is expanding into Alabama

STAT

As for-profit Tenet Healthcare slims its hospital portfolio, it found an unlikely buyer for its Alabama hospitals: Florida’s Orlando Health.   Orlando Health draws more than $6 billion in annual revenue and has a profit margin that surpasses most of its peers. A hospital system executive system leader said crossing state lines to buy five Birmingham-area hospitals is part of its focus on serving the Southeastern U.S., even though most of its 17 existing hospitals are still in Fl

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Pharmacies can play a vital role in encouraging blood donations

The Pharmacist

The shortage of blood stocks, particularly group O red cells, remains acute, and the NHS’s amber alert remains in place. Pharmacies have a role to play in encouraging more blood donors, says Dr Avinash Hari Narayanan, clinical lead at the London Medical Laboratory The NHS continues to appeal for people with O-type blood to donate, […] The post Pharmacies can play a vital role in encouraging blood donations appeared first on The Pharmacist.

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STAT+: A U.K. trade group scolds Novo again — this time for remarks made by its CEO

STAT

Once again, Novo Nordisk has been admonished by a U.K. trade group for violating voluntary marketing codes and discrediting the entire pharmaceutical industry — and the move comes just one year after the company was suspended from the organization for the way it promoted an obesity drug. In the latest episode, the company was cited for “misleading” and “unbalanced” comments made by its chief executive officer, Lars Fruergaard Jørgensen, to The Sunday Times

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Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

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Nutraceutical brand Aurelle Health launches in India

Express Pharma

Aurelle Health, a D2C Nutraceutical brand aimed to prioritise women’s hormonal health, has been launched in India. Taking its lineage from Balaxi Pharmaceuticals, the inception of the brand is based on the statistics that 1 out of every 5 Indian women suffer from hormonal issues like Polycystic Ovary Syndrome (PCOS). The brand further aims to educate women about their hormone health.

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Listen: VC struggles, drug pricing negotiations, & Novo’s abrupt Wegovy decision

STAT

Why did Novo Nordisk pull its paperwork to expand the use of Wegovy for a common type of heart failure? How will we know if the the government gets a good deal in the first round of drug pricing negotiations? And has Allison thought about anything other than venture capital for the last couple of months? We discuss all that and more on this week’s episode of “The Readout LOUD.

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Another baby dies from whooping cough as cases surpass 10,000

The Pharmacist

A further baby died from whooping cough in England in June, bringing the total to 10 since the start of the latest outbreak in November last year. New data published today by the UK Health Security Agency (UKHSA) also revealed laboratory confirmed cases during the outbreak has now surpassed 10,000. In response, UKHSA reiterated advice […] The post Another baby dies from whooping cough as cases surpass 10,000 appeared first on The Pharmacist.

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STAT+: Medicare paid substantially more for J&J’s Stelara when it was covered under Part D than under Part B

STAT

A popular biologic medicine used to combat autoimmune diseases cost Medicare and its beneficiaries considerably more when the injectable treatment was obtained at pharmacies rather than injected in physician offices due to different methods for determining payment, a new analysis found. The drug in question is Stelara, which is made by Johnson & Johnson and approved to combat psoriasis, psoriatic arthritis, Crohn’s disease, and ulcerative colitis.

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5 Reasons to Upgrade Your Pharmacy Management Software

Are you still using workarounds to manage your daily operations? To achieve peak performance, it's time to explore other options for specialty and infusion pharmacy software. Streamline pharmacy operations and improve clinical performance with automated processing, real-time data exchange, and electronic decision support. Download this helpful infographic to: Drive efficiency and patient adherence from referral receipt to delivery and ongoing care – all with our Pharmacy Cloud.

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You’re trusted less than a waiter and more than a pilot, but why?

pharmaphorum

Discover why pharmaceutical companies are trusted less than a waiter, but more than a pilot, and explore the role of Patient Advocacy Groups (PAGs) in shaping trust in the pharmaceutical industry.

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Talkspace earnings, a framework for detecting AI hallucination, and trends in telehealth abortions

STAT

You’re reading the web edition of STAT’s Health Tech newsletter, our guide to how technology is transforming the life sciences.  Sign up to get it delivered in your inbox every Tuesday and Thursday. How UnitedHealth used a questionable artery-screening program to boost payments My colleagues’ relentless examination of the nation’s largest health insurer has turned up yet another problematic practice: Pushing clinicians to use a thinly tested medical device to scr

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How Universal Brain is using neuroscience to transform psychiatric care

Outsourcing Pharma

In the evolving landscape of precision psychiatry, Universal Brain stands at the forefront, focusing on neuroscience and technology to transform the standard of care for psychiatric conditions.

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STAT+: Pharmalittle: We’re reading about a Purdue overdose-reversal device, a discontinued Merck trial, and more

STAT

Top of the morning to you, and a fine one it is, despite the gray skies hovering over the Pharmalot campus. We are doing our best to maintain sunny spirits, though, because once again, we recall some helpful wisdom from the Morning Mayor, who taught us that “Every new day should be unwrapped like a precious gift.” To celebrate the notion, we are brewing still more cups of stimulation and inviting you to join us.

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Obesity drug tirzepatide approval in China strengthens market position amid GLP-1 agonist competition: GlobalData

Express Pharma

Eli Lilly’s tirzepatide (Mounjaro) has recently been approved by the National Medical Products Administration (NMPA) for treating obesity. This approval, based on the positive results from the SURMOUNT-CN clinical trial, makes tirzepatide the first dual glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptor agonist approved for obesity treatment in China, which is expected to enhance its market positioning in the country, says GlobalData.

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STAT+: A strong start for Madrigal’s MASH drug launch

STAT

This is the online edition of Adam’s Biotech Scorecard, a subscriber-only newsletter. STAT+ subscribers can sign up  here  to get it delivered to their inbox. I fractured my elbow over the weekend. I’ll spare you all the details except to say scampering across slippery rocks is not a great idea. Perhaps my biggest mistake was believing that I’m nimble enough to scamper over anything.

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AI biotechs Exscientia and Recursion agree $688m merger

pharmaphorum

Recursion Pharma has agreed to merge with rival AI-powered drug discovery firm Exscientia in an all-stock deal valued at $688 million

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Purdue receives clearance for opioid overdose injector for younger individuals

Pharmaceutical Technology

Coming in response to a rise in teenage overdoses across the US, the Purdue auto-injector device is designed to be used by anyone.

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Pharma Pulse 8/8/24: Addressing Maternal Health Disparities and Driving Change, Abacavir Increases Cardiovascular Risk in Patients With HIV & more

Pharmaceutical Commerce

Business strategies and top news in the biotech / biopharma industry, including market access, supply chain distribution and more.

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Does Roche have buyer's remorse for Flatiron takeover?

pharmaphorum

Roche is said to be considering a sale of cancer data specialist Flatiron Health, just a few years after it bought the company for $1.

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