Mon.Jun 17, 2024

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New Merck pneumococcal vaccine wins FDA approval

STAT

The Food and Drug Administration on Monday approved Merck’s new pneumococcal vaccine for adults 18 and older. The vaccine, which will be sold under the name Capvaxive, is designed to protect against pneumococcal pneumonia, which hospitalizes about 150,000 adults in the United States every year and kills about 1 in 20 who develop it, according to the National Foundation for Infectious Diseases.

Vaccines 363
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The hunt for the brain’s biomarkers

PharmaVoice

How Roche is finding better ways to diagnose brain conditions like Alzheimer’s and Parkinson’s disease.

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Trending Sources

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Bird flu snapshot: A critic of the U.S. response speaks out, and USDA tries to ‘corner the virus’

STAT

Bird flu snapshot: This is the first in a series of regular updates on H5N1 avian flu that STAT is publishing on Monday mornings. To read future updates you can also subscribe to STAT’s Morning Rounds newsletter. Seth Berkley, the former head of Gavi, the Vaccine Alliance, gave voice last week to a point of view STAT has been hearing for a while about the U.S. response to the H5N1 bird flu outbreak in dairy cows.

Vaccines 363
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Leuko device to remotely monitor cancer patients during chemotherapy

Pharma Times

Cancer was estimated to be responsible for more than 18 million cases worldwide in 2020

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Navigating Payroll Compliance: Future-Proofing Payroll in an Evolving Regulatory Landscape

Speaker: Jennifer Hill

Payroll compliance is a cornerstone of business success, yet for small and midsize businesses, it’s becoming increasingly challenging to navigate the ever-evolving landscape of federal, state, and local regulations. Mistakes can lead to costly penalties and operational disruptions, making it essential to adopt advanced solutions that ensure accuracy and efficiency.

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Vaping is just as good as Chantix at helping people quit cigarettes, new study finds

STAT

WASHINGTON — E-cigarettes were about as effective at helping people quit smoking as the gold-standard pharmaceutical drug, varenicline, according to a clinical trial published Monday in JAMA Internal Medicine. The trial randomized 458 people who smoked daily and wanted to quit to receive either a nicotine-containing e-cigarette and placebo tablets, varenicline and an e-cigarette without nicotine, or a placebo tablet and a nicotine-free e-cigarette for 12 weeks.

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Novavax seeks FDA approval for updated Covid-19 vaccine

Pharmaceutical Technology

Novavax has sought US FDA approval for an updated JN.1 version of its Covid-19 vaccine, NVX-CoV2705, for individuals aged 12 years and above.

Vaccines 145

More Trending

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Ten-minute brain scan could improve diagnosis for paediatric brain cancer

Pharma Times

Medulloblastoma is responsible for around 52 new cases in children in the UK every year

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What’s the evidence for the Surgeon General’s proposed social media warning?

STAT

United States Surgeon General Vivek Murthy wants to add a warning label on social media. “It is time to require a surgeon general’s warning label on social media platforms, stating that social media is associated with significant mental health harms for adolescents,” he wrote in an op-ed published on Monday in the New York Times, calling on Congress to take action to add the warning, which would be along the lines of the ones issued against tobacco and alcohol consumption.

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New data showcase promise, growing pains of CAR-T in autoimmune disease

BioPharma Dive

One expert described trial results presented at EULAR last week as “unprecedented.” But reports of relapses in some patients drew questions about the therapies’ ultimate potential.

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STAT+: Former medical device CEO who sold fake plastic parts sentenced to 6 years in prison

STAT

The former CEO of Stimwave, a company that sold pain-relief devices with dummy pieces of plastic, was sentenced Monday by a New York judge to six years in prison.  Stimwave sold nerve stimulation devices to combat pain. Under CEO Laura Perryman’s leadership, the company warped the design of their devices to earn more reimbursement money from insurers, resulting in unnecessary plastic parts that allowed doctors to claim around $18,000 more than they previously could.

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From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

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How can you prepare pharmaceutical data for AI consumption?

PharmaVoice

While AI has exploded in popularity across various industries, including pharma and life sciences, many companies have launched models that haven't delivered on their full potential.

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Opinion: I’m a hypochondriac. Here’s how the health care system needs to deal with people like me

STAT

A late-night Flomax commercial is sometimes all it takes for me to start spinning in a cycle of anxiety. If I don’t need Flomax to help me pee better, then I imagine I probably need a screening for prostate cancer. I’m a hypochondriac. I’m also a health care executive with insight into how the U.S. health care system works — and doesn’t work — which may contribute to my hyper focus on health.

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PulmCrit: Bilevel Sequence Intubation (BSI) – The new standard

EMCrit Project

introduction Bilevel Sequence Intubation (BSI) refers to initiation of noninvasive bilevel positive pressure ventilation with a backup rate prior to intubation (either using a BiPAP machine or a full-featured mechanical ventilator). BSI is distinct from traditional rapid sequence intubation (RSI), since BSI involves the delivery of machine-initiated, pressure-controlled breaths following administration of sedation and paralytics. […] EMCrit Project by Josh Farkas.

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STAT+: Under pressure to thwart pharma patent abuse, the PTO proposes a new rule. But will it fly?

STAT

In a bid to prevent the patent system from being abused, the U.S. Patent and Trademark Office has proposed a new rule designed to stem the use of so-called patent thickets , which are wielded by pharmaceutical companies to delay the arrival of lower-cost generic medicines in the marketplace. Essentially, thickets are collections of numerous patents that add only incremental changes to a drug and, therefore, produce little to no additional benefit to patients.

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Why Every Small Business Needs an HCM Solution: A Comprehensive Guide

Managing HR tasks like payroll, compliance, and employee data can overwhelm small businesses. That’s where a Human Capital Management (HCM) solution comes in. Our eBook, Why Every Small Business Needs an HCM Solution: A Comprehensive Guide , shows how an HCM system automates tedious processes, ensuring your business stays compliant and efficient. You’ll learn how to simplify payroll, eliminate costly errors, and empower your employees with self-service tools.

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Could Amazon or Google hold the key to the future of public health diagnostics?

pharmaphorum

Discover how leading tech giants such as Amazon, Google, Apple, and Microsoft are shaping the future of public health diagnostics through MedTech innovations. Explore the potential impact on healthcare and stay informed on the latest developments.

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STAT+: Why health care spending keeps climbing

STAT

You’re reading the web version of Health Care Inc., STAT’s weekly newsletter following the flow of money in medicine. Sign up to get it in your inbox every Monday. Putting your money where your mouth is Large companies rarely switch health insurance vendors. It’s a pain in the butt for everyone involved, even if the current setup is a raw deal.

Hospitals 297
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Upscaling your brand strategy: New ways of planning

pharmaphorum

Learn how to upscale your brand strategy with new and innovative ways of planning. Discover effective brand planning strategies to take your brand to the next level.

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STAT+: Why a big California employer ditched Elevance for some of its health plans

STAT

The California Public Employees’ Retirement System is making a drastic change to one of its major health insurance plans for the state’s employees and retirees: It’s switching health insurance carriers, and forcing its new partners to earn their fees instead of automatically getting them. The new contract could serve as a model for other large employers that are fully on the hook for their workers’ health care costs and want their insurance companies to do more to kee

Hospitals 297
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Best Practices to Streamline Compensation Management: A Foundation for Growth

Speaker: Joe Sharpe and James Carlson

Payroll optimization can be one of the most time-consuming and complex factors of small business management. Yet, organizations that crack the code on streamlining employee compensation often discover innovative avenues for growth. With the right strategies in place, outsourcing and streamlining payroll processes can result in substantial time and resource savings.

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New data at EHA backs Sanofi, Innate’s NK cell engager

pharmaphorum

Sanofi and Innate Pharma NK cell engager therapy SAR443579 shows promising efficacy in AML patients in a phase 1/2 trial reported at EHA.

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FDA offers new guidelines for Covid-19 vaccine

STAT

Want to stay on top of the science and politics driving biotech today?  Sign up  to get our biotech newsletter in your inbox. Hello! Today, we talk about the uptick in physicians using ctDNA to determine if resected cancers are truly gone, we see the FDA offering new guidelines for Covid-19 vaccines, and more.

Vaccines 280
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Address the impact of trending health information with conversation data

pharmaphorum

Explore the impact and influence of trending health information, like Ozempic and the Eddy Effect on platforms like TikTok, through conversation data analysis. Learn more about these trends and their implications.

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STAT+: Pharmalittle: We’re reading about an ‘unaffordable’ Novartis drug, a proposed patent rule, and more

STAT

Good morning, everyone, and welcome to another working week. We hope the weekend respite was relaxing and invigorating, because that oh-so-familiar routine of deadlines, online meetings, and hustling about has predictably returned. But what can you do? The world, such as it is, continues to spin. So to nudge it in a direction that is a bit less wobbly, we are brewing a cup of stimulation.

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Enhance Healthcare Efficiency With Top Payroll & HCM Services

Running a healthcare facility requires precision and care, not just for patients but also for your staff. Our guide, "A Buyer’s Guide to Payroll & HCM Services," helps healthcare providers choose the best provider. Efficient payroll management ensures timely, accurate payments, critical for maintaining staff morale and trust. Compliance support helps navigate complex healthcare regulations and avoid costly fines.

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CALQUENCE plus chemoimmunotherapy reduced the risk of disease progression or death by 27% vs. standard of care in patients with untreated mantle cell lymphoma in ECHO Phase III trial

Express Pharma

The recent results from the ECHO Phase III trial showed AstraZeneca’s CALQUENCE (acalabrutinib) in combination with bendamustine and rituximab demonstrated an improvement in progression-free survival (PFS) and showed a favourable trend in overall survival (OS) compared to standard-of-care chemoimmunotherapy (bendamustine plus rituximab) in previously untreated patients with mantle cell lymphoma (MCL).

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Epilepsy fail hands late-stage pipeline blow to Takeda

pharmaphorum

Takeda’s experimental epilepsy drug soticlestat has failed phase 3 trials in Dravet syndrome and Lennox-Gastaut syndrome

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Ascentage Pharma signs option agreement with Takeda

Express Pharma

Ascentage Pharma, a global biopharmaceutical company engaged in developing therapies for cancer, chronic hepatitis B (CHB), and age-related diseases, recently announced the signing of an option agreement with Takeda to enter into an exclusive licence agreement for olverembatinib, an oral, BCR-ABL tyrosine kinase inhibitor (TKI), which is currently in development for chronic myeloid leukaemia (CML) and other haematological cancers.

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Telehealth firm fraud charges may worsen ADHD drug shortage

pharmaphorum

Two executives at telehealth startup Done Global have been arrested and face allegations of fraud involving the distribution of medicines for ADHD

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Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

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Divisional Patent Minefields: Navigating Big Pharma’s Patent Extension Strategies

Drug Patent Watch

The article “The devil is in the divisional: an analysis of divisional patents, deadlines, declarations and suggestions for future practice” by Mieke Filler provides a comprehensive analysis of the strategic use of divisional patents in the pharmaceutical sector to delay generic and biosimilar market entry.

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The critical role of comprehensive RNA sequencing in liquid biopsy for biomarker discovery and clinical trials

BioPharma Dive

Elevate precision medicine: dose optimization and immune monitoring through advanced liquid biopsies.

Immunity 109
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Innovative Approaches to Extend the Life of Drug Patents

Drug Patent Watch

Pharmaceutical companies employ various strategies to extend the commercial life and patent protection of successful drugs. Here are some key approaches with examples: New Formulations One common strategy is to develop and patent new formulations of the existing drug compound to provide benefits like reduced dosing frequency, easier administration, improved bioavailability, or reduced side effects.

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Study finds low secondary cancer risk with CAR-Ts

pharmaphorum

Stanford Medicine study finds risk of secondary cancers with CAR-T therapies is low and likely unrelated to the treatments themselves

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5 Reasons to Upgrade Your Pharmacy Management Software

Are you still using workarounds to manage your daily operations? To achieve peak performance, it's time to explore other options for specialty and infusion pharmacy software. Streamline pharmacy operations and improve clinical performance with automated processing, real-time data exchange, and electronic decision support. Download this helpful infographic to: Drive efficiency and patient adherence from referral receipt to delivery and ongoing care – all with our Pharmacy Cloud.